{"disease":{"id":"restless-legs-syndrome","name":"restless legs syndrome"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05044520","title":"Clinical Features Associated With Restless Legs Syndrome.","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT01887613","title":"Specified Drug Use-Results Survey of Regnite","phase":"","overall_status":"COMPLETED","enrollment_count":1597,"lead_sponsor_name":"Astellas Pharma Inc","has_results":false},{"nct_id":"NCT01327339","title":"REQUIP RLS Post Marketing Surveillance","phase":"","overall_status":"COMPLETED","enrollment_count":755,"lead_sponsor_name":"GlaxoSmithKline","has_results":true},{"nct_id":"NCT04827329","title":"Anesthetic Management of Patients With Chronic Sleep Disorders","phase":"","overall_status":"COMPLETED","enrollment_count":700,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT04141891","title":"Advancing Understanding of Transportation Options","phase":"NA","overall_status":"COMPLETED","enrollment_count":529,"lead_sponsor_name":"University of Colorado, Denver","has_results":true},{"nct_id":"NCT05321355","title":"Mainz Register of Patients With Sleep Disorders","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Johannes Gutenberg University Mainz","has_results":false},{"nct_id":"NCT03053427","title":"A Study of Oral Dosing of Gabapentin Enacarbil in Japanese Restless Legs Syndrome Patients","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":375,"lead_sponsor_name":"Astellas Pharma Inc","has_results":true},{"nct_id":"NCT03457571","title":"Clinical Observational Study: IBD Patients With Restless-legs-syndrome and Iron Deficiency Syndrome","phase":"","overall_status":"COMPLETED","enrollment_count":353,"lead_sponsor_name":"Charite University, Berlin, Germany","has_results":false},{"nct_id":"NCT06684782","title":"Prevalence and Characteristics of Restless Leg Syndrome in Thai Patients With Parkinson's Disease","phase":"","overall_status":"RECRUITING","enrollment_count":310,"lead_sponsor_name":"Siriraj Hospital","has_results":false},{"nct_id":"NCT07117591","title":"Restless Legs Syndrome and Sleep Quality in Pes Planus","phase":"","overall_status":"COMPLETED","enrollment_count":242,"lead_sponsor_name":"Bozok University","has_results":false},{"nct_id":"NCT01823354","title":"Executive Dysfunction in Restless Legs Syndrome: Clinical Correlates and Outcome After Therapeutic Management","phase":"NA","overall_status":"RECRUITING","enrollment_count":176,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT04906486","title":"Autonomic Assessment in Patients With Restless Legs Syndrome","phase":"","overall_status":"COMPLETED","enrollment_count":155,"lead_sponsor_name":"Kocaeli Derince Education and Research Hospital","has_results":false},{"nct_id":"NCT00256854","title":"Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":135,"lead_sponsor_name":"GlaxoSmithKline","has_results":true},{"nct_id":"NCT04874155","title":"Noninvasive Peripheral Nerve Stimulation for Medication-Refractory Primary RLS (The RESTFUL Study)","phase":"NA","overall_status":"COMPLETED","enrollment_count":133,"lead_sponsor_name":"Noctrix Health, Inc.","has_results":true},{"nct_id":"NCT01823770","title":"Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs Syndrome","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":130,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT05985421","title":"Gut Microbiota and Bacterial Translocation in Restless Legs Syndrome","phase":"","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT04161027","title":"RCT for Pregabalin in Restless Legs Syndrome in South Korea","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":116,"lead_sponsor_name":"Seoul National University Hospital","has_results":false},{"nct_id":"NCT05908214","title":"The Application of Wide Pulse High Frequency Neuromuscular Electrical Stimulation in Disorders Associated With Motoneuron Hyperexcitability","phase":"NA","overall_status":"RECRUITING","enrollment_count":110,"lead_sponsor_name":"University of Lausanne","has_results":false},{"nct_id":"NCT05196828","title":"Extension Study Evaluating NTX100 Neuromodulation System for Medication-Refractory Primary RLS","phase":"NA","overall_status":"COMPLETED","enrollment_count":103,"lead_sponsor_name":"Noctrix Health, Inc.","has_results":true},{"nct_id":"NCT07292077","title":"Restless Legs Syndrome in Temporomandibular Joint Disorders","phase":"","overall_status":"COMPLETED","enrollment_count":102,"lead_sponsor_name":"Gulseren Demir Karakilic","has_results":false},{"nct_id":"NCT04786314","title":"The Effect of Hot and Cold Water Application on Pregnant Women With Restless Leg Syndrome","phase":"NA","overall_status":"UNKNOWN","enrollment_count":90,"lead_sponsor_name":"TC Erciyes University","has_results":false},{"nct_id":"NCT00051961","title":"Effect of Ropinirole on Spinal Cord Reflexes and Restless Legs Syndrome","phase":"","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"National Institute of Neurological Disorders and Stroke (NINDS)","has_results":false},{"nct_id":"NCT06468371","title":"Exercise Training Versus Ropinirole in Treating Restless Legs Syndrome Among Hemodialysis Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":84,"lead_sponsor_name":"Lahore General Hospital","has_results":false},{"nct_id":"NCT04759703","title":"Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD","phase":"PHASE2, PHASE3","overall_status":"TERMINATED","enrollment_count":75,"lead_sponsor_name":"Massachusetts General Hospital","has_results":true},{"nct_id":"NCT06889324","title":"Efficacy of Vibration Therapy on Restless Legs Syndrome and Sleep Disturbances Among Patients Undergoing Hemodialysis","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":70,"lead_sponsor_name":"Amjed Abdulabbas Shraida","has_results":false},{"nct_id":"NCT02826681","title":"Randomized, Placebo-controlled Trial of Ferric Carboxymaltose in RLS Patients With Iron-deficiency Anemia","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":70,"lead_sponsor_name":"American Regent, Inc.","has_results":true},{"nct_id":"NCT05795868","title":"The Effect of Compression Stockings on the Complaints of Pregnant Women With Restless Leg Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":70,"lead_sponsor_name":"TC Erciyes University","has_results":false},{"nct_id":"NCT05851001","title":"Effects of Progressive Muscle Relaxation Exercises During Pregnancy","phase":"NA","overall_status":"COMPLETED","enrollment_count":67,"lead_sponsor_name":"Ege University","has_results":false},{"nct_id":"NCT06156007","title":"Effect of Progressive Muscle Relaxation Exercises in Menopausal Women Experiencing RLS.","phase":"NA","overall_status":"COMPLETED","enrollment_count":62,"lead_sponsor_name":"Gazi University","has_results":false},{"nct_id":"NCT05214963","title":"Noninvasive Peripheral Nerve Stimulation for Medication-Naive and Medication-Refractory RLS","phase":"NA","overall_status":"COMPLETED","enrollment_count":58,"lead_sponsor_name":"Noctrix Health, Inc.","has_results":false},{"nct_id":"NCT04853771","title":"The Effect of Progressive Muscle Relaxation Exercise Training Given to Pregnant Women With Restless Leg Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":52,"lead_sponsor_name":"Gazi University","has_results":false},{"nct_id":"NCT03806530","title":"DIalysis Symptom COntrol-Restless Legs Syndrome Trial","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":52,"lead_sponsor_name":"Population Health Research Institute","has_results":false},{"nct_id":"NCT06631300","title":"A Randomized, Placebo-controlled Trial of Prednisone in Refractory Restless Legs Syndrome: a Pilot Study","phase":"PHASE1, PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":50,"lead_sponsor_name":"Scripps Health","has_results":false},{"nct_id":"NCT04145674","title":"A Proof of Concept, Phase 2, Double-blind, Randomized Trial With d-Methadone Product Versus Placebo","phase":"PHASE2","overall_status":"SUSPENDED","enrollment_count":50,"lead_sponsor_name":"Mauro Manconi","has_results":false},{"nct_id":"NCT05698420","title":"Investigation of the Effects of Medium Cut-off Dialyzers Versus High-Flux Dialyzers on Clinical and Laboratory Parameters of Prevalent Hemodialysis Patients","phase":"","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"Sanliurfa Mehmet Akif Inan Education and Research Hospital","has_results":false},{"nct_id":"NCT04706091","title":"Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic Insomnia","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":46,"lead_sponsor_name":"Massachusetts General Hospital","has_results":true},{"nct_id":"NCT00074672","title":"Relationship Between Sensory and Motor Systems in Restless Leg Syndrome","phase":"","overall_status":"COMPLETED","enrollment_count":45,"lead_sponsor_name":"National Institute of Neurological Disorders and Stroke (NINDS)","has_results":false},{"nct_id":"NCT04700683","title":"Noninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":43,"lead_sponsor_name":"Noctrix Health, Inc.","has_results":false},{"nct_id":"NCT05787080","title":"Massage, Oxidative and Antioxidant Enzymes in Hemodialysis Patients With Restless Legs Syndrome(RLS)","phase":"NA","overall_status":"COMPLETED","enrollment_count":42,"lead_sponsor_name":"Baskent University","has_results":false},{"nct_id":"NCT03570515","title":"Yoga vs. Education for Restless Legs Syndrome: a Feasibility Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":41,"lead_sponsor_name":"West Virginia University","has_results":false},{"nct_id":"NCT06806891","title":"Restless Leg Syndrome: Is There a Response to Buddhist Walking Meditation in Hemodialysis","phase":"NA","overall_status":"RECRUITING","enrollment_count":40,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT04316052","title":"Aerobic And Strength Training Exercises For Restless Leg Syndrome In Patients With Diabetes","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"Riphah International University","has_results":false},{"nct_id":"NCT02929732","title":"Analysis of Sympathetic Activity in Willis-Ekbom Disease","phase":"NA","overall_status":"RECRUITING","enrollment_count":40,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT00530790","title":"Clinical Evaluation of Ropinirole CR-RLS ( SK&F101468)Tablets in Restless Legs Syndrome","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":35,"lead_sponsor_name":"GlaxoSmithKline","has_results":true},{"nct_id":"NCT00996944","title":"Clinical Evaluation of Ropinirole IR (Immediate Release) Tablets in Patients Who Are Diagnosed With Symptomatic Restless Legs Syndrome (RLS) Associated With Chronic Kidney Disease (CKD) Managed With Haemodialysis (Including Haemofiltration and Haemodiafiltration)","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":34,"lead_sponsor_name":"GlaxoSmithKline","has_results":true},{"nct_id":"NCT00419692","title":"Restless Legs Patient Study On Absorption, Distribution, Metabolism And Excretion Of Ropinirole And The Effect Of Food","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":32,"lead_sponsor_name":"GlaxoSmithKline","has_results":false},{"nct_id":"NCT05573711","title":"Restless Legs Syndrome in People With Neuromyelitis Optica Spectrum Disorder","phase":"","overall_status":"UNKNOWN","enrollment_count":30,"lead_sponsor_name":"Dokuz Eylul University","has_results":false},{"nct_id":"NCT03345953","title":"Clinical Trial Assessing the Efficacy and Safety of BP1.4979 in Restless Legs Syndrome","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":29,"lead_sponsor_name":"Bioprojet","has_results":false},{"nct_id":"NCT04887103","title":"The Effect of Hot Water Application in Pregnant Women With Restless Legs Syndrome: A Randomised Controlled Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":29,"lead_sponsor_name":"TC Erciyes University","has_results":false},{"nct_id":"NCT02526277","title":"A Study on the Use of the MMF07 Foot Massager and Heat Therapy Treatments for Restless Leg Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":28,"lead_sponsor_name":"Ariane Park","has_results":true}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}