{"disease":{"id":"restless-leg-syndrome","name":"restless leg syndrome"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05044520","title":"Clinical Features Associated With Restless Legs Syndrome.","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT01887613","title":"Specified Drug Use-Results Survey of Regnite","phase":"","overall_status":"COMPLETED","enrollment_count":1597,"lead_sponsor_name":"Astellas Pharma Inc","has_results":false},{"nct_id":"NCT01327339","title":"REQUIP RLS Post Marketing Surveillance","phase":"","overall_status":"COMPLETED","enrollment_count":755,"lead_sponsor_name":"GlaxoSmithKline","has_results":true},{"nct_id":"NCT04827329","title":"Anesthetic Management of Patients With Chronic Sleep Disorders","phase":"","overall_status":"COMPLETED","enrollment_count":700,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT04141891","title":"Advancing Understanding of Transportation Options","phase":"NA","overall_status":"COMPLETED","enrollment_count":529,"lead_sponsor_name":"University of Colorado, Denver","has_results":true},{"nct_id":"NCT07083492","title":"Non-invasive Detection of Iron Deficiency in Obstetrics","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Wuerzburg University Hospital","has_results":false},{"nct_id":"NCT05321355","title":"Mainz Register of Patients With Sleep Disorders","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Johannes Gutenberg University Mainz","has_results":false},{"nct_id":"NCT03053427","title":"A Study of Oral Dosing of Gabapentin Enacarbil in Japanese Restless Legs Syndrome Patients","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":375,"lead_sponsor_name":"Astellas Pharma Inc","has_results":true},{"nct_id":"NCT03457571","title":"Clinical Observational Study: IBD Patients With Restless-legs-syndrome and Iron Deficiency Syndrome","phase":"","overall_status":"COMPLETED","enrollment_count":353,"lead_sponsor_name":"Charite University, Berlin, Germany","has_results":false},{"nct_id":"NCT01538147","title":"Restless Leg Syndrome and Severe Preeclampsia","phase":"","overall_status":"COMPLETED","enrollment_count":310,"lead_sponsor_name":"Saint Thomas Hospital, Panama","has_results":false},{"nct_id":"NCT06684782","title":"Prevalence and Characteristics of Restless Leg Syndrome in Thai Patients With Parkinson's Disease","phase":"","overall_status":"RECRUITING","enrollment_count":310,"lead_sponsor_name":"Siriraj Hospital","has_results":false},{"nct_id":"NCT07117591","title":"Restless Legs Syndrome and Sleep Quality in Pes Planus","phase":"","overall_status":"COMPLETED","enrollment_count":242,"lead_sponsor_name":"Bozok University","has_results":false},{"nct_id":"NCT01823354","title":"Executive Dysfunction in Restless Legs Syndrome: Clinical Correlates and Outcome After Therapeutic Management","phase":"NA","overall_status":"RECRUITING","enrollment_count":176,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT04906486","title":"Autonomic Assessment in Patients With Restless Legs Syndrome","phase":"","overall_status":"COMPLETED","enrollment_count":155,"lead_sponsor_name":"Kocaeli Derince Education and Research Hospital","has_results":false},{"nct_id":"NCT00256854","title":"Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":135,"lead_sponsor_name":"GlaxoSmithKline","has_results":true},{"nct_id":"NCT04874155","title":"Noninvasive Peripheral Nerve Stimulation for Medication-Refractory Primary RLS (The RESTFUL Study)","phase":"NA","overall_status":"COMPLETED","enrollment_count":133,"lead_sponsor_name":"Noctrix Health, Inc.","has_results":true},{"nct_id":"NCT01823770","title":"Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs Syndrome","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":130,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT05985421","title":"Gut Microbiota and Bacterial Translocation in Restless Legs Syndrome","phase":"","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT04161027","title":"RCT for Pregabalin in Restless Legs Syndrome in South Korea","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":116,"lead_sponsor_name":"Seoul National University Hospital","has_results":false},{"nct_id":"NCT05908214","title":"The Application of Wide Pulse High Frequency Neuromuscular Electrical Stimulation in Disorders Associated With Motoneuron Hyperexcitability","phase":"NA","overall_status":"RECRUITING","enrollment_count":110,"lead_sponsor_name":"University of Lausanne","has_results":false},{"nct_id":"NCT05196828","title":"Extension Study Evaluating NTX100 Neuromodulation System for Medication-Refractory Primary RLS","phase":"NA","overall_status":"COMPLETED","enrollment_count":103,"lead_sponsor_name":"Noctrix Health, Inc.","has_results":true},{"nct_id":"NCT07292077","title":"Restless Legs Syndrome in Temporomandibular Joint Disorders","phase":"","overall_status":"COMPLETED","enrollment_count":102,"lead_sponsor_name":"Gulseren Demir Karakilic","has_results":false},{"nct_id":"NCT00051961","title":"Effect of Ropinirole on Spinal Cord Reflexes and Restless Legs Syndrome","phase":"","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"National Institute of Neurological Disorders and Stroke (NINDS)","has_results":false},{"nct_id":"NCT04786314","title":"The Effect of Hot and Cold Water Application on Pregnant Women With Restless Leg Syndrome","phase":"NA","overall_status":"UNKNOWN","enrollment_count":90,"lead_sponsor_name":"TC Erciyes University","has_results":false},{"nct_id":"NCT06468371","title":"Exercise Training Versus Ropinirole in Treating Restless Legs Syndrome Among Hemodialysis Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":84,"lead_sponsor_name":"Lahore General Hospital","has_results":false},{"nct_id":"NCT07199504","title":"A Self-Controlled Study on the Treatment of Restless Legs Syndrome in Uremia With Dipyridamole","phase":"PHASE2, PHASE3","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":80,"lead_sponsor_name":"Yunfeng Xia","has_results":false},{"nct_id":"NCT04759703","title":"Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD","phase":"PHASE2, PHASE3","overall_status":"TERMINATED","enrollment_count":75,"lead_sponsor_name":"Massachusetts General Hospital","has_results":true},{"nct_id":"NCT02826681","title":"Randomized, Placebo-controlled Trial of Ferric Carboxymaltose in RLS Patients With Iron-deficiency Anemia","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":70,"lead_sponsor_name":"American Regent, Inc.","has_results":true},{"nct_id":"NCT05795868","title":"The Effect of Compression Stockings on the Complaints of Pregnant Women With Restless Leg Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":70,"lead_sponsor_name":"TC Erciyes University","has_results":false},{"nct_id":"NCT06889324","title":"Efficacy of Vibration Therapy on Restless Legs Syndrome and Sleep Disturbances Among Patients Undergoing Hemodialysis","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":70,"lead_sponsor_name":"Amjed Abdulabbas Shraida","has_results":false},{"nct_id":"NCT05851001","title":"Effects of Progressive Muscle Relaxation Exercises During Pregnancy","phase":"NA","overall_status":"COMPLETED","enrollment_count":67,"lead_sponsor_name":"Ege University","has_results":false},{"nct_id":"NCT06156007","title":"Effect of Progressive Muscle Relaxation Exercises in Menopausal Women Experiencing RLS.","phase":"NA","overall_status":"COMPLETED","enrollment_count":62,"lead_sponsor_name":"Gazi University","has_results":false},{"nct_id":"NCT07224932","title":"Tolerability and Efficacy of CBD Extract for RLS Treatment","phase":"PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":60,"lead_sponsor_name":"University of Colorado, Denver","has_results":false},{"nct_id":"NCT05214963","title":"Noninvasive Peripheral Nerve Stimulation for Medication-Naive and Medication-Refractory RLS","phase":"NA","overall_status":"COMPLETED","enrollment_count":58,"lead_sponsor_name":"Noctrix Health, Inc.","has_results":false},{"nct_id":"NCT03818243","title":"Circadian Character of Food Compulsions and Impulses Control Disorders in Parkinsonian Patients With and Without Resting Leg Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":55,"lead_sponsor_name":"University Hospital, Clermont-Ferrand","has_results":false},{"nct_id":"NCT07276828","title":"Effect of Autogenic Training on Hemodialysis Patients","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":54,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT04853771","title":"The Effect of Progressive Muscle Relaxation Exercise Training Given to Pregnant Women With Restless Leg Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":52,"lead_sponsor_name":"Gazi University","has_results":false},{"nct_id":"NCT07110961","title":"The Suggested Immobilization Test With Exploratory Heart Rate Variability Analysis for Diagnosis of Restless Legs Syndrome","phase":"NA","overall_status":"RECRUITING","enrollment_count":52,"lead_sponsor_name":"Siriraj Hospital","has_results":false},{"nct_id":"NCT03806530","title":"DIalysis Symptom COntrol-Restless Legs Syndrome Trial","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":52,"lead_sponsor_name":"Population Health Research Institute","has_results":false},{"nct_id":"NCT06726785","title":"Observe Change in Nasal Swab DRD2 Gene Expression in Restless Legs Syndrome (RLS) Patients on Prolonged Dopamine Agonist Treatment","phase":"","overall_status":"RECRUITING","enrollment_count":50,"lead_sponsor_name":"HBC Immunology Inc","has_results":false},{"nct_id":"NCT05698420","title":"Investigation of the Effects of Medium Cut-off Dialyzers Versus High-Flux Dialyzers on Clinical and Laboratory Parameters of Prevalent Hemodialysis Patients","phase":"","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"Sanliurfa Mehmet Akif Inan Education and Research Hospital","has_results":false},{"nct_id":"NCT06631300","title":"A Randomized, Placebo-controlled Trial of Prednisone in Refractory Restless Legs Syndrome: a Pilot Study","phase":"PHASE1, PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":50,"lead_sponsor_name":"Scripps Health","has_results":false},{"nct_id":"NCT04145674","title":"A Proof of Concept, Phase 2, Double-blind, Randomized Trial With d-Methadone Product Versus Placebo","phase":"PHASE2","overall_status":"SUSPENDED","enrollment_count":50,"lead_sponsor_name":"Mauro Manconi","has_results":false},{"nct_id":"NCT07179406","title":"The Effect of Spinal Cord Stimulators on Restless Leg Syndrome","phase":"NA","overall_status":"RECRUITING","enrollment_count":50,"lead_sponsor_name":"University of Alabama at Birmingham","has_results":false},{"nct_id":"NCT04706091","title":"Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic Insomnia","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":46,"lead_sponsor_name":"Massachusetts General Hospital","has_results":true},{"nct_id":"NCT00074672","title":"Relationship Between Sensory and Motor Systems in Restless Leg Syndrome","phase":"","overall_status":"COMPLETED","enrollment_count":45,"lead_sponsor_name":"National Institute of Neurological Disorders and Stroke (NINDS)","has_results":false},{"nct_id":"NCT04700683","title":"Noninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":43,"lead_sponsor_name":"Noctrix Health, Inc.","has_results":false},{"nct_id":"NCT05787080","title":"Massage, Oxidative and Antioxidant Enzymes in Hemodialysis Patients With Restless Legs Syndrome(RLS)","phase":"NA","overall_status":"COMPLETED","enrollment_count":42,"lead_sponsor_name":"Baskent University","has_results":false},{"nct_id":"NCT03570515","title":"Yoga vs. Education for Restless Legs Syndrome: a Feasibility Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":41,"lead_sponsor_name":"West Virginia University","has_results":false},{"nct_id":"NCT06806891","title":"Restless Leg Syndrome: Is There a Response to Buddhist Walking Meditation in Hemodialysis","phase":"NA","overall_status":"RECRUITING","enrollment_count":40,"lead_sponsor_name":"Cairo University","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}