{"disease":{"id":"respiratory-distress-syndrome-adult","name":"respiratory distress syndrome adult"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06430619","title":"Can Novel Oxygenation Indices Guide the Diagnosis of Acute Respiratory Distress Syndrome","phase":"","overall_status":"COMPLETED","enrollment_count":2000,"lead_sponsor_name":"Başakşehir Çam & Sakura City Hospital","has_results":false},{"nct_id":"NCT04378582","title":"Characteristics and Outcomes of Patients With COVID-19 Admitted to the ICU","phase":"","overall_status":"COMPLETED","enrollment_count":1589,"lead_sponsor_name":"University of Sao Paulo General Hospital","has_results":false},{"nct_id":"NCT02759770","title":"Risk Factors and Prediction Score of ARDS After Cardiac Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":1333,"lead_sponsor_name":"Beijing Anzhen Hospital","has_results":false},{"nct_id":"NCT03188770","title":"Practice of Ventilation in Middle-Income Countries","phase":"","overall_status":"COMPLETED","enrollment_count":1315,"lead_sponsor_name":"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","has_results":false},{"nct_id":"NCT03368092","title":"Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"University Hospital, Strasbourg, France","has_results":false},{"nct_id":"NCT05604430","title":"Pre-hospital Ventilation Clinical Study","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":500,"lead_sponsor_name":"Zoll Medical Corporation","has_results":false},{"nct_id":"NCT03236272","title":"Establishment of a Biomarkers-based Early Warning System of Acute Respiratory Distress Syndrome (ARDS)","phase":"","overall_status":"UNKNOWN","enrollment_count":376,"lead_sponsor_name":"Mingdong Hu","has_results":false},{"nct_id":"NCT04545424","title":"Trial of Therapeutic Hypothermia in Patients With ARDS","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":340,"lead_sponsor_name":"University of Maryland, Baltimore","has_results":false},{"nct_id":"NCT02622724","title":"Efficacy and Safety of FP-1201-lyo (Interferon Beta-1a) in Patients Having Acute Respiratory Distress Syndrome (ARDS)","phase":"PHASE3","overall_status":"TERMINATED","enrollment_count":301,"lead_sponsor_name":"Faron Pharmaceuticals Ltd","has_results":true},{"nct_id":"NCT06199141","title":"Multi-drug Resistant Gram-negative Bacteria and Veno-venous Extracorporeal Membrane Oxygenation (ECMO)","phase":"","overall_status":"COMPLETED","enrollment_count":279,"lead_sponsor_name":"University of Padova","has_results":false},{"nct_id":"NCT03971331","title":"The Value of Combined Critical Care Ultrasound and PAC Monitor Oriented Therapy Protocol to Patients of ARDS With ACP","phase":"NA","overall_status":"UNKNOWN","enrollment_count":236,"lead_sponsor_name":"Kang Yan","has_results":false},{"nct_id":"NCT06203405","title":"The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial","phase":"NA","overall_status":"RECRUITING","enrollment_count":214,"lead_sponsor_name":"Siriraj Hospital","has_results":false},{"nct_id":"NCT04635267","title":"Effects of Extravascular Lung Water on Prone Position Efficacy in Patients With ARDS","phase":"","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Bicetre Hospital","has_results":false},{"nct_id":"NCT04516486","title":"Coronavirus Studied by Metagenomics in ARDS COVID-19 Patients","phase":"","overall_status":"UNKNOWN","enrollment_count":180,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT03709199","title":"Long Term Follow up of Children Enrolled in the REDvent Study","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":176,"lead_sponsor_name":"Children's Hospital Los Angeles","has_results":false},{"nct_id":"NCT04139733","title":"Early Use of Prone Position in ECMO for Severe ARDS","phase":"","overall_status":"COMPLETED","enrollment_count":160,"lead_sponsor_name":"Beijing Chao Yang Hospital","has_results":false},{"nct_id":"NCT03111212","title":"Iloprost in Acute Respiratory Distress Syndrome","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"University Hospital Tuebingen","has_results":false},{"nct_id":"NCT03818854","title":"Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"Michael A. Matthay","has_results":true},{"nct_id":"NCT03969914","title":"PEEP-induced Changed in RRI as Physiological Background of Ventilator-induced Kidney Injury","phase":"","overall_status":"COMPLETED","enrollment_count":105,"lead_sponsor_name":"Università degli Studi di Ferrara","has_results":false},{"nct_id":"NCT02273687","title":"Time-motion-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in Emergency Department","phase":"NA","overall_status":"COMPLETED","enrollment_count":104,"lead_sponsor_name":"Centre Hospitalier Universitaire de Nīmes","has_results":false},{"nct_id":"NCT02439151","title":"New Lung Ventilation Strategies Guided by Transpulmonary Pressure in VV-ECMO for Severe ARDS","phase":"NA","overall_status":"COMPLETED","enrollment_count":104,"lead_sponsor_name":"Rui Wang","has_results":false},{"nct_id":"NCT04520815","title":"Prevalence and Kinetics of Diaphragmatic Dysfunction in Elderly Patients With Acute Respiratory Distress","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Centre Hospitalier Universitaire de la Réunion","has_results":false},{"nct_id":"NCT04395105","title":"Dexamethasone for COVID-19 Related ARDS: a Multicenter, Randomized Clinical Trial","phase":"PHASE3","overall_status":"TERMINATED","enrollment_count":100,"lead_sponsor_name":"Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno","has_results":false},{"nct_id":"NCT05083130","title":"Awake Prone Positioning in Moderate to Severe COVID-19","phase":"NA","overall_status":"COMPLETED","enrollment_count":93,"lead_sponsor_name":"Oxford University Clinical Research Unit, Vietnam","has_results":false},{"nct_id":"NCT04710329","title":"High-Dose Vitamin C Treatment in Critically Ill COVID-19 Patients","phase":"","overall_status":"COMPLETED","enrollment_count":78,"lead_sponsor_name":"Sisli Hamidiye Etfal Training and Research Hospital","has_results":false},{"nct_id":"NCT03539783","title":"Identifying PARDS Endotypes","phase":"","overall_status":"COMPLETED","enrollment_count":76,"lead_sponsor_name":"Children's Hospital Medical Center, Cincinnati","has_results":false},{"nct_id":"NCT04744090","title":"Roflumilast as add-on Therapy in Early Cases of ARDS","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":76,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT06775210","title":"Effect of Implementing Sleep Care Bundle on Nurses' Practice and Patients' Outcomes","phase":"NA","overall_status":"COMPLETED","enrollment_count":66,"lead_sponsor_name":"Mansoura University","has_results":false},{"nct_id":"NCT04510662","title":"Telmisartan in Respiratory Failure Due to COVID-19","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":66,"lead_sponsor_name":"Abraham Edgar Gracia-Ramos","has_results":false},{"nct_id":"NCT05496868","title":"Add-on Reparixin in Adult Patients With ARDS","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":66,"lead_sponsor_name":"Dompé Farmaceutici S.p.A","has_results":false},{"nct_id":"NCT05210881","title":"Weaning From Nasal High Flow Therapy","phase":"","overall_status":"COMPLETED","enrollment_count":62,"lead_sponsor_name":"Hôpital Louis Mourier","has_results":false},{"nct_id":"NCT04345887","title":"Spironolactone in Covid-19 Induced ARDS","phase":"","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Istanbul University - Cerrahpasa","has_results":false},{"nct_id":"NCT02097641","title":"Human Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome (START)","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Michael A. Matthay","has_results":true},{"nct_id":"NCT06159465","title":"Utility of Defining ARDS and Past and Current Definitions of ARDS","phase":"","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"NMC Specialty Hospital","has_results":false},{"nct_id":"NCT03788096","title":"Peer Support for Post Intensive Care Syndrome Self-Management","phase":"NA","overall_status":"UNKNOWN","enrollment_count":40,"lead_sponsor_name":"University of Texas at Austin","has_results":false},{"nct_id":"NCT04388826","title":"COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":39,"lead_sponsor_name":"Veru Inc.","has_results":true},{"nct_id":"NCT03202394","title":"Evaluation of Safety & Efficacy of BIO-11006 Inhalation Solution in Patients With ARDS","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":38,"lead_sponsor_name":"BioMarck Pharmaceuticals, Ltd.","has_results":false},{"nct_id":"NCT00094406","title":"Carbon Monoxide to Prevent Lung Inflammation","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":35,"lead_sponsor_name":"National Institutes of Health Clinical Center (CC)","has_results":false},{"nct_id":"NCT03807804","title":"Efficacy and Safety Study of HLCM051(MultiStem®) for Pneumonic Acute Respiratory Distress Syndrome","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":35,"lead_sponsor_name":"Healios K.K.","has_results":false},{"nct_id":"NCT02221037","title":"Study of GSK2862277 in Subjects Undergoing Oesophagectomy Surgery","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":35,"lead_sponsor_name":"GlaxoSmithKline","has_results":true},{"nct_id":"NCT03712215","title":"STUDY OF ELECTRICAL STIMULATION IN PULMONARY FUNCTION IN INTENSIVE CARE UNIT","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Universidade Metodista de Piracicaba","has_results":false},{"nct_id":"NCT02664090","title":"Hemodynamic Assessment With Trans-esophageal Doppler (TED) During Prone Ventilation in ARDS Patients","phase":"","overall_status":"COMPLETED","enrollment_count":26,"lead_sponsor_name":"Sanjay Gandhi Postgraduate Institute of Medical Sciences","has_results":false},{"nct_id":"NCT04106128","title":"Prevalence, Impact and Reversibility of Acute Diaprhagmatic Dysfunction in Acute Respiratory Detresse","phase":"NA","overall_status":"COMPLETED","enrollment_count":25,"lead_sponsor_name":"Centre Hospitalier Universitaire de Nice","has_results":false},{"nct_id":"NCT04297397","title":"Personalised Simulation Technologies for Optimising Treatment in the Intensive Care Unit","phase":"","overall_status":"COMPLETED","enrollment_count":25,"lead_sponsor_name":"Guy's and St Thomas' NHS Foundation Trust","has_results":false},{"nct_id":"NCT04778059","title":"Safety and Efficacy of USB002 for Respiratory Distress Due to COVID-19","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":21,"lead_sponsor_name":"US Biotest, Inc.","has_results":true},{"nct_id":"NCT04382391","title":"Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms","phase":"NA","overall_status":"TERMINATED","enrollment_count":21,"lead_sponsor_name":"Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)","has_results":true},{"nct_id":"NCT05715762","title":"Determine the Effects of Prone Positioning and NO in COVID-19 ARDS by EIT","phase":"","overall_status":"UNKNOWN","enrollment_count":20,"lead_sponsor_name":"Shanghai Zhongshan Hospital","has_results":false},{"nct_id":"NCT04582201","title":"A Clinical Trial to Evaluate the Safety of agenT-797 in COVID-19 Participants With ARDS","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":20,"lead_sponsor_name":"MiNK Therapeutics","has_results":false},{"nct_id":"NCT07492888","title":"Nogapendekin Alfa-Inbakicept and iNKT Cells for Critically Ill Adults With Severe Community-Acquired Pneumonia (With or Without Sepsis/ARDS)","phase":"PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":20,"lead_sponsor_name":"ImmunityBio, Inc.","has_results":false},{"nct_id":"NCT04012073","title":"Individualized Positive End-expiratory Pressure Guided by End-expiratory Lung Volume in the Acute Respiratory Distress Syndrome","phase":"PHASE3","overall_status":"TERMINATED","enrollment_count":18,"lead_sponsor_name":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}