{"disease":{"id":"reduce-or-prevent-hemorrhage-in-hemophilia-patients-during-tooth-extraction","name":"Reduce or prevent hemorrhage in hemophilia patients during tooth extraction","therapeutic_area":"","data":{},"enrichment_level":0,"last_enriched_at":null,"visit_count":0,"created_at":"2026-04-19T18:31:21.150Z","updated_at":"2026-04-19T18:39:44.960Z","meddra_pt":null,"meddra_code":null,"icd10_codes":null,"synonyms":[],"prevalence_global":null,"prevalence_us":null,"marketed_drug_count":1,"pipeline_drug_count":0,"trial_count":0},"drugs":{"marketed":[{"drug_id":"cyklokapron","indication_name":"Reduce or prevent hemorrhage in hemophilia patients during tooth extraction","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Cyklokapron","generic_name":"Tranexamic Acid","company_name":"Pfizer Inc.","drug_phase":"marketed","molecular_target":"Plasminogen lysine binding sites; fibrin","drug_class":"Antifibrinolytic agent","quality_score":60,"revenue":null,"mechanism":"Tranexamic acid occupies lysine receptor binding sites on plasmin, preventing fibrin dissolution."}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[],"total":0},"guidelines":[{"drug_id":"cyklokapron","guideline_body":"FDA label","recommendation":"Tranexamic acid injection, USP is indicated in patients with hemophilia for short-term use (2 to 8 days) to reduce or prevent hemorrhage during tooth extraction.","line_of_therapy":"adjuvant","evidence_grade":"B","guideline_year":null},{"drug_id":"cyklokapron","guideline_body":"FDA label","recommendation":"Tranexamic acid injection, USP is indicated in patients with hemophilia for short-term use (2 to 8 days) to reduce or prevent hemorrhage following tooth extraction.","line_of_therapy":"adjuvant","evidence_grade":"B","guideline_year":null},{"drug_id":"cyklokapron","guideline_body":"FDA label","recommendation":"Tranexamic acid injection, USP is indicated in patients with hemophilia for short-term use (2 to 8 days) to reduce the need for replacement therapy during tooth extraction.","line_of_therapy":"adjuvant","evidence_grade":"B","guideline_year":null},{"drug_id":"cyklokapron","guideline_body":"FDA label","recommendation":"Tranexamic acid injection, USP is indicated in patients with hemophilia for short-term use (2 to 8 days) to reduce the need for replacement therapy following tooth extraction.","line_of_therapy":"adjuvant","evidence_grade":"B","guideline_year":null}],"source":"Drug Landscape verified database"}