{"disease":{"id":"plasmodium-falciparum-infection","name":"plasmodium falciparum infection"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05400655","title":"Anti-malaria MAb in Kenyan Children","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":912,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":true},{"nct_id":"NCT03996967","title":"Diagnostic and Prognostic Biomarkers for Childhood Bacterial Pneumonia","phase":"","overall_status":"COMPLETED","enrollment_count":837,"lead_sponsor_name":"Boston University","has_results":false},{"nct_id":"NCT05816330","title":"L9LS MAb in Malian Adults","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":490,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":true},{"nct_id":"NCT02497612","title":"To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":377,"lead_sponsor_name":"Sanofi","has_results":true},{"nct_id":"NCT05304611","title":"Anti-malaria MAb in Malian Children","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":365,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":true},{"nct_id":"NCT04329104","title":"Safety and Efficacy of CIS43LS Anti-malaria mAb in Mali","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":348,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":true},{"nct_id":"NCT07122232","title":"Comparative Study of Thrombocytopenia in Plasmodium Vivax and Falciparum Malaria","phase":"","overall_status":"COMPLETED","enrollment_count":177,"lead_sponsor_name":"Rafiullah Hotak","has_results":false},{"nct_id":"NCT02020330","title":"Optimising Operational Use of Artemether-lumefantrine Comparing 3 Day Versus 5 Day","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"University of Oxford","has_results":false},{"nct_id":"NCT03660839","title":"Study to Investigate the Clinical and Parasiticidal Activity and Pharmacokinetics of Different Doses of Artefenomel and Ferroquine in Patients With Uncomplicated Plasmodium Falciparum Malaria","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":140,"lead_sponsor_name":"Sanofi","has_results":true},{"nct_id":"NCT02663700","title":"Safety and Immunogenicity of Sanaria's Irradiated Sporozoite Vaccine (PfSPZ Vaccine) in Malaria-Experienced Adults in Burkina Faso","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":112,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":false},{"nct_id":"NCT05750459","title":"Pharmacokinetic Study of IV Artesunate to Treat Children With Severe Malaria","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":false},{"nct_id":"NCT03589794","title":"rCSP/AP10-602 [GLA-LSQ] Vaccine Trial","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":65,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":false},{"nct_id":"NCT02996695","title":"Safety and Efficacy of Sanaria's PfSPZ-CVac in Malian Adults","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":62,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":false},{"nct_id":"NCT02780154","title":"PfSPZ Challenge in Non-immune Adults in Baltimore, USA","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":false},{"nct_id":"NCT02773979","title":"PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":28,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":false},{"nct_id":"NCT03014258","title":"A Systems Biology Approach to Malaria Immunity","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":27,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":false},{"nct_id":"NCT03168854","title":"Trial to Evaluate the Safety, Immunogenicity and Protective Efficacy of Three or Five Administrations of GAP3KO Sporozoites","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":26,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":false},{"nct_id":"NCT03138096","title":"Safety and Protective Efficacy of Pb(PfCS@UIS4)","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":24,"lead_sponsor_name":"Radboud University Medical Center","has_results":true}],"total":18},"guidelines":[],"source":"Drug Landscape verified database"}