{"disease":{"id":"persistent-atrial-fibrillation","name":"persistent atrial fibrillation"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04088071","title":"Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation","phase":"","overall_status":"RECRUITING","enrollment_count":15000,"lead_sponsor_name":"Heart Rhythm Clinical and Research Solutions, LLC","has_results":false},{"nct_id":"NCT05006456","title":"Real-world Experience of Catheter Ablation Using Novel Ablation Technologies for the Treatment of Atrial Fibrillation","phase":"","overall_status":"UNKNOWN","enrollment_count":4000,"lead_sponsor_name":"Beijing Anzhen Hospital","has_results":false},{"nct_id":"NCT05773170","title":"Efficacy and Safety Evaluation of Refralon®, Concentrate for Solution for Intravenous Injection in Patients With Paroxysmal and Persistent Atrial Fibrillation and Flutter","phase":"","overall_status":"COMPLETED","enrollment_count":1147,"lead_sponsor_name":"R-Pharm","has_results":false},{"nct_id":"NCT07508618","title":"Study on the Prevention of Atrial Fibrillation Recurrence After Ablation by Qidong Yixin Granule","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":846,"lead_sponsor_name":"Sir Run Run Shaw Hospital","has_results":false},{"nct_id":"NCT06791629","title":"Pulsed Field Ablation Versus Radiofrequency Ablation for Persistent Atrial Fibrillation","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":700,"lead_sponsor_name":"Beijing Anzhen Hospital","has_results":false},{"nct_id":"NCT05443594","title":"A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects With Persistent Atrial Fibrillation","phase":"NA","overall_status":"COMPLETED","enrollment_count":669,"lead_sponsor_name":"Boston Scientific Corporation","has_results":true},{"nct_id":"NCT07106970","title":"PVI Alone vs PVI and Linear Ablation for Persistent Atrial Fibrillation (PROMPT AF II)","phase":"NA","overall_status":"RECRUITING","enrollment_count":640,"lead_sponsor_name":"Boston Scientific Corporation","has_results":false},{"nct_id":"NCT04497376","title":"Comparison Between Upgraded '2C3L' vs. PVI Approach for Catheter Ablation of Persistent Atrial Fibrillation","phase":"NA","overall_status":"COMPLETED","enrollment_count":498,"lead_sponsor_name":"Beijing Anzhen Hospital","has_results":false},{"nct_id":"NCT06096337","title":"Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":484,"lead_sponsor_name":"Boston Scientific Corporation","has_results":false},{"nct_id":"NCT05776797","title":"AV Junction Ablation or Optimal Medical Treatment in PatiEnts With Cardiac Resynchronization Therapy and Permanent Atrial Fibrillation","phase":"NA","overall_status":"RECRUITING","enrollment_count":480,"lead_sponsor_name":"University Hospital Ostrava","has_results":false},{"nct_id":"NCT05264831","title":"Pulmonary Vein Isolation Alone or in Combination With Substrate Modulation After Electric Cardioversion Failure","phase":"NA","overall_status":"RECRUITING","enrollment_count":450,"lead_sponsor_name":"Elsan","has_results":false},{"nct_id":"NCT06671197","title":"Study on the Ablation of Persistent Atrial Fibrillation Using Pulsed Electric Fields Under Different Surgical Procedures","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":436,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT07298473","title":"Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)","phase":"NA","overall_status":"RECRUITING","enrollment_count":400,"lead_sponsor_name":"Medtronic Cardiac Ablation Solutions","has_results":false},{"nct_id":"NCT06223789","title":"VOLT-AF IDE Clinical Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":392,"lead_sponsor_name":"Abbott Medical Devices","has_results":false},{"nct_id":"NCT06633523","title":"Optimized Posterior Left Atrial Wall Ablation Strategy for PeAF","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":384,"lead_sponsor_name":"Shanghai Chest Hospital","has_results":false},{"nct_id":"NCT07122336","title":"Optimized Ablation of the Posterior Wall in Persistent Atrial Fibrillation","phase":"NA","overall_status":"RECRUITING","enrollment_count":384,"lead_sponsor_name":"Shanghai Chest Hospital","has_results":false},{"nct_id":"NCT03733392","title":"Advisor HD Grid Observational Study","phase":"","overall_status":"COMPLETED","enrollment_count":379,"lead_sponsor_name":"Abbott Medical Devices","has_results":true},{"nct_id":"NCT03643224","title":"DiamondTemp™ System for the Treatment of Persistent Atrial Fibrillation","phase":"NA","overall_status":"COMPLETED","enrollment_count":376,"lead_sponsor_name":"Medtronic Cardiac Ablation Solutions","has_results":true},{"nct_id":"NCT04542785","title":"Lenient Rate Control Versus Strict Rate Control for Atrial Fibrillation. The Danish Atrial Fibrillation Randomised Clinical Trial","phase":"NA","overall_status":"UNKNOWN","enrollment_count":350,"lead_sponsor_name":"Holbaek Sygehus","has_results":false},{"nct_id":"NCT07445360","title":"Circumferential Pulmonary Venous Isolation Combined With Bachmann Bundle Modification Versus Circumferential Pulmonary Venous Isolation for Persistent Atrial Fibrillation","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":320,"lead_sponsor_name":"Shenyang Northern Hospital","has_results":false},{"nct_id":"NCT05922917","title":"Pulsed-field Ablation in Patients With Persistent Atrial Fibrillation","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":300,"lead_sponsor_name":"České Budějovice Hospital","has_results":false},{"nct_id":"NCT03882021","title":"High-Density (HD) Wave Mapping in Subjects With Atrial Fibrillation as a Predictor of Recurrence After a Single Ablation Procedure Using a PVI-Only Strategy","phase":"NA","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"Abbott Medical Devices","has_results":true},{"nct_id":"NCT05085912","title":"Driver Ablation of Persistent Atrial Fibrillation With Severe Atrial Fibrosis.","phase":"NA","overall_status":"UNKNOWN","enrollment_count":300,"lead_sponsor_name":"Shanghai Chest Hospital","has_results":false},{"nct_id":"NCT05153486","title":"Catheter Ablation and Surgical Ablation of Persistent Atrial Fibrillation With Severe Atrial Fibrosis","phase":"NA","overall_status":"UNKNOWN","enrollment_count":300,"lead_sponsor_name":"Shanghai Chest Hospital","has_results":false},{"nct_id":"NCT07064616","title":"Pulsed Field Ablation vs. Cryoballoon Ablation in Patients With Persistent Atrial Fibrillation","phase":"NA","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Kitasato University","has_results":false},{"nct_id":"NCT07153718","title":"Optimal Ablation Strategies for Persistent AF With HF","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":300,"lead_sponsor_name":"Xu Liu","has_results":false},{"nct_id":"NCT04405258","title":"Left Atrial Posterior Wall Additional Isolation for Persistent Atrial Fibrillation Trial","phase":"PHASE4","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":276,"lead_sponsor_name":"Institute for Clinical Effectiveness, Japan","has_results":false},{"nct_id":"NCT07535268","title":"REPRESENT-PF Registry","phase":"","overall_status":"RECRUITING","enrollment_count":275,"lead_sponsor_name":"Vivek Reddy","has_results":false},{"nct_id":"NCT06765356","title":"Pragmatic Evaluation of a Pentaspline Pulsed Field Ablation System to Treat Atrial Fibrillation and Related Arrhythmias","phase":"PHASE4","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":275,"lead_sponsor_name":"Vivek Reddy","has_results":false},{"nct_id":"NCT06510556","title":"Feasibility Study of the FARAFLEX Mapping and PFA System","phase":"NA","overall_status":"RECRUITING","enrollment_count":250,"lead_sponsor_name":"Boston Scientific Corporation","has_results":false},{"nct_id":"NCT06529978","title":"Endocardial Mapping With the CoreMap EP Mapping System","phase":"NA","overall_status":"RECRUITING","enrollment_count":245,"lead_sponsor_name":"CoreMap Inc.","has_results":false},{"nct_id":"NCT03650556","title":"Safety and Effectiveness of TactiCath™ Contact Force, Sensor Enabled™ (TactiCath SE) Catheter for Ablation of Drug Refractory, Symptomatic, Persistent Atrial Fibrillation","phase":"NA","overall_status":"COMPLETED","enrollment_count":224,"lead_sponsor_name":"Abbott Medical Devices","has_results":true},{"nct_id":"NCT07405359","title":"PVI Alone Versus PVI Plus PWI and SVCI With PFA","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":220,"lead_sponsor_name":"Edward Gerstenfeld, MD","has_results":false},{"nct_id":"NCT05104658","title":"Heart Rehabilitation for All","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":218,"lead_sponsor_name":"Center for Clinical Research and Prevention","has_results":false},{"nct_id":"NCT04061603","title":"iCLAS™ for Persistent Atrial Fibrillation","phase":"NA","overall_status":"COMPLETED","enrollment_count":215,"lead_sponsor_name":"Adagio Medical","has_results":false},{"nct_id":"NCT06096246","title":"Investigation of Cardioversion Versus Therapeutic Ablation for Persistent AF (ORBICA-AF)","phase":"NA","overall_status":"RECRUITING","enrollment_count":208,"lead_sponsor_name":"Barts & The London NHS Trust","has_results":false},{"nct_id":"NCT05468528","title":"Clinical Value of Linear Ablation Without Pulmonary Vein Isolation in Persistent Atrial Fibrillation","phase":"NA","overall_status":"UNKNOWN","enrollment_count":207,"lead_sponsor_name":"China National Center for Cardiovascular Diseases","has_results":false},{"nct_id":"NCT05986526","title":"The PIFPAF-PFA Study","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":206,"lead_sponsor_name":"Insel Gruppe AG, University Hospital Bern","has_results":false},{"nct_id":"NCT05826665","title":"Observational Study to Examine the Procedural and Outcomes of AF Ablation Assisted by STAR Apollo™ Mapping System","phase":"","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"Kansas City Heart Rhythm Research Foundation","has_results":false},{"nct_id":"NCT03091972","title":"Liner Ablation Using Contact-force in Atrial Fibrillation","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Korea University Anam Hospital","has_results":false},{"nct_id":"NCT03053570","title":"Study Comparing Pulmonary Vein Isolation With the Cryoballoon and Radiofrequency Energy(Contact Force) in the Treatment of Persistent Atrial Fibrillation (AF) (Cryo Vs CF in PerAF)","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"China Cardiometabolic Registries","has_results":false},{"nct_id":"NCT04022954","title":"HD Mapping of Atrial Fibrillation in Asia Pacific","phase":"","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Abbott Medical Devices","has_results":true},{"nct_id":"NCT03044925","title":"Remote Magnetic Navigation-guided Ablation Versus Cryoablation for Persistent Atrial Fibrillation (RECREATION Study)","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Ruijin Hospital","has_results":false},{"nct_id":"NCT07382024","title":"Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":200,"lead_sponsor_name":"National Taiwan University Hospital","has_results":false},{"nct_id":"NCT05454111","title":"CARTO-Finder Guided Ablation Versus Multiscale Entropy Guided Ablation in Persistent Atrial Fibrillation","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Shanghai Chest Hospital","has_results":false},{"nct_id":"NCT06837441","title":"PerAF: AF Termination vs Prespecified Ablation","phase":"NA","overall_status":"COMPLETED","enrollment_count":195,"lead_sponsor_name":"Shanghai Chest Hospital","has_results":false},{"nct_id":"NCT05227586","title":"Adjunctive Right Atrial Ablation for Persistent Atrial Fibrillation With Right Atrial Enlargement","phase":"","overall_status":"COMPLETED","enrollment_count":195,"lead_sponsor_name":"Shanghai Chest Hospital","has_results":false},{"nct_id":"NCT06415149","title":"High-Power, Short-Duration Ablation in Treatment of Patients With Atrial Fibrillation","phase":"NA","overall_status":"COMPLETED","enrollment_count":185,"lead_sponsor_name":"People's Friendship University of Russia","has_results":false},{"nct_id":"NCT04067427","title":"Reducing Recurrence of Symptomatic Atrial Fibrillation After Catheter Ablation by App-based Mental Training","phase":"NA","overall_status":"COMPLETED","enrollment_count":183,"lead_sponsor_name":"Helios Health Institute GmbH","has_results":false},{"nct_id":"NCT04085731","title":"Driver-guided Ablation of Persistent Atrial Fibrillatiom","phase":"","overall_status":"UNKNOWN","enrollment_count":181,"lead_sponsor_name":"IRCCS Policlinico S. Donato","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}