{"disease":{"id":"peripheral-neuropathic-pain","name":"Peripheral neuropathic pain","therapeutic_area":"","data":{},"enrichment_level":0,"last_enriched_at":null,"visit_count":0,"created_at":"2026-04-19T18:31:21.150Z","updated_at":"2026-04-19T18:39:44.960Z","meddra_pt":null,"meddra_code":null,"icd10_codes":null,"synonyms":[],"prevalence_global":null,"prevalence_us":null,"marketed_drug_count":1,"pipeline_drug_count":0,"trial_count":2},"drugs":{"marketed":[{"drug_id":"mirogabalin","indication_name":"Peripheral neuropathic pain","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Tarlige","generic_name":"MIROGABALIN","company_name":"Daiichi Sankyo","drug_phase":"marketed","molecular_target":"Voltage-dependent calcium channel subunit alpha-2/delta-1","drug_class":"","quality_score":35,"revenue":"300","mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06546202","title":"Real-World Pharmacological Treatment Pattern of Neuropathic Pain in China","phase":"","overall_status":"COMPLETED","enrollment_count":1271,"lead_sponsor_name":"Daiichi Sankyo","has_results":false},{"nct_id":"NCT06628908","title":"Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":1100,"lead_sponsor_name":"Vertex Pharmaceuticals Incorporated","has_results":false},{"nct_id":"NCT07231419","title":"Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":734,"lead_sponsor_name":"Vertex Pharmaceuticals Incorporated","has_results":false},{"nct_id":"NCT06812117","title":"A Study to Evaluate the Safety and Effectiveness of Mirogabalin in Chinese Adult Patients With Diabetic Peripheral Neuropathic Pain (DPNP) in Real-world Clinical Practice Setting (ReMIssion Study)","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":721,"lead_sponsor_name":"Daiichi Sankyo","has_results":false},{"nct_id":"NCT04647773","title":"To Evaluate the Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Diabetic Peripheral Neuropathic Pain","phase":"PHASE2, PHASE3","overall_status":"UNKNOWN","enrollment_count":687,"lead_sponsor_name":"Haisco Pharmaceutical Group Co., Ltd.","has_results":false},{"nct_id":"NCT04171453","title":"Post-marketing Surveillance (PMS) to Observe the Safety and Effectiveness of Lyrica CR Extended Release Tablets","phase":"","overall_status":"UNKNOWN","enrollment_count":600,"lead_sponsor_name":"Viatris Korea","has_results":false},{"nct_id":"NCT06203002","title":"A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":496,"lead_sponsor_name":"Lexicon Pharmaceuticals","has_results":false},{"nct_id":"NCT06696443","title":"Evaluation of the Long-term Safety and Effectiveness of Suzetrigine (SUZ) in Participants With Painful Diabetic Peripheral Neuropathy (DPN)","phase":"PHASE3","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":455,"lead_sponsor_name":"Vertex Pharmaceuticals Incorporated","has_results":false},{"nct_id":"NCT05817591","title":"Response Profiles to High-concentration Capsaicin Desensitization in Patients with Peripheral Neuropathic Pain with or Without Allodynia: a Regional Multicenter Prospective Cohort","phase":"","overall_status":"RECRUITING","enrollment_count":400,"lead_sponsor_name":"Centre Hospitalier Annecy Genevois","has_results":false},{"nct_id":"NCT04094662","title":"A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled 14-week Study of DS-5565 in Chinese Patients With Diabetic Peripheral Neuropathic Pain","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":393,"lead_sponsor_name":"Daiichi Sankyo Co., Ltd.","has_results":false},{"nct_id":"NCT02985216","title":"Clinical Trial of YHD1119 in Patients With Peripheral Neuropathic Pain","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":371,"lead_sponsor_name":"Yuhan Corporation","has_results":false},{"nct_id":"NCT05351801","title":"Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":320,"lead_sponsor_name":"VA Office of Research and Development","has_results":false},{"nct_id":"NCT05890053","title":"To Evaluate the Long-term Safety and Efficacy of HSK16149 in Chinese Patients With Peripheral Neuralgia","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":301,"lead_sponsor_name":"Haisco Pharmaceutical Group Co., Ltd.","has_results":false},{"nct_id":"NCT06619860","title":"Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Vertex Pharmaceuticals Incorporated","has_results":false},{"nct_id":"NCT04146896","title":"Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy (DPN)","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":228,"lead_sponsor_name":"Aptinyx","has_results":true},{"nct_id":"NCT04953221","title":"The Effect of YJ001 on Diabetic Peripheral Neuropathic Pain.","phase":"","overall_status":"UNKNOWN","enrollment_count":225,"lead_sponsor_name":"Peking University Third Hospital","has_results":false},{"nct_id":"NCT06221241","title":"Evaluate the Efficacy and Safety of JMKX000623 in Participants With Diabetic Peripheral Neuropathic Pain","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":220,"lead_sponsor_name":"Jemincare","has_results":false},{"nct_id":"NCT05895552","title":"A Study of RTA 901 (BIIB143) in Participants With Diabetic Peripheral Neuropathic Pain","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":209,"lead_sponsor_name":"Reata, a wholly owned subsidiary of Biogen","has_results":true},{"nct_id":"NCT06490445","title":"A Study of Medical Cannabis Aerosol Via the Fixed-dose Syqe Inhaler as an Add-on Treatment of Diabetic Peripheral Neuropathic Pain (DPNP)","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":192,"lead_sponsor_name":"Syqe Medical","has_results":false},{"nct_id":"NCT04688671","title":"Efficacy and Safety of ETX-018810 for the Treatment of Diabetic Peripheral Neuropathic Pain","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":167,"lead_sponsor_name":"Eliem Therapeutics (UK) Ltd.","has_results":true},{"nct_id":"NCT05177094","title":"Chronic Pain Master Protocol (CPMP): A Study of LY3526318 in Participants With Diabetic Peripheral Neuropathic Pain","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":155,"lead_sponsor_name":"Eli Lilly and Company","has_results":true},{"nct_id":"NCT04184596","title":"Preferences in Pain Treatment: A Discrete Choice Experiment in Patients With Peripheral Neuropathic Pain (pNP)","phase":"","overall_status":"COMPLETED","enrollment_count":153,"lead_sponsor_name":"LinkCare GmbH","has_results":false},{"nct_id":"NCT06596122","title":"Vitamin D Supplementation in Breast Cancer Patients","phase":"PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":132,"lead_sponsor_name":"Abdelrahman Mahmoud","has_results":false},{"nct_id":"NCT05620576","title":"A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05).","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":131,"lead_sponsor_name":"Eli Lilly and Company","has_results":true},{"nct_id":"NCT04476108","title":"Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Diabetic Peripheral Neuropathic Pain","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":125,"lead_sponsor_name":"Eli Lilly and Company","has_results":true},{"nct_id":"NCT06091020","title":"A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve Injury","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":123,"lead_sponsor_name":"Merz Therapeutics GmbH","has_results":false},{"nct_id":"NCT01416116","title":"Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":122,"lead_sponsor_name":"Astellas Pharma Inc","has_results":false},{"nct_id":"NCT03346330","title":"Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), Food-effect of TRK-750","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":105,"lead_sponsor_name":"Toray Industries, Inc","has_results":false},{"nct_id":"NCT04429919","title":"AP-325 in Subjects With Peripheral Post-surgical Neuropathic Pain","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":99,"lead_sponsor_name":"Algiax Pharmaceuticals GmbH","has_results":false},{"nct_id":"NCT06490484","title":"Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Diabetic Peripheral Neuropathic Pain Who Had an Inadequate Response to Pregabalin","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":90,"lead_sponsor_name":"Haisco Pharmaceutical Group Co., Ltd.","has_results":false},{"nct_id":"NCT05219812","title":"A Study to Learn How Safe BAY2395840 is and How Well it Works in Participants Who Have Diabetic Nerve Pain","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":80,"lead_sponsor_name":"Bayer","has_results":false},{"nct_id":"NCT04707157","title":"Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Diabetic Peripheral Neuropathic Pain","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":68,"lead_sponsor_name":"Eli Lilly and Company","has_results":true},{"nct_id":"NCT04431778","title":"Evaluation of the Efficacy and Tolerance of Low Doses of Ethosuximide in the Treatment of Peripheral Neuropathic Pain","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":64,"lead_sponsor_name":"University Hospital, Clermont-Ferrand","has_results":false},{"nct_id":"NCT06737861","title":"Buerger Exercises With Whole Body Vibration in Diabetic Peripheral Neuropathy","phase":"NA","overall_status":"COMPLETED","enrollment_count":64,"lead_sponsor_name":"Riphah International University","has_results":false},{"nct_id":"NCT06290661","title":"Clinical Trial of the Safety and Efficacy of Peripheral Nerve Stimulation in the Treatment of Peripheral Neuropathic Pain.","phase":"NA","overall_status":"RECRUITING","enrollment_count":60,"lead_sponsor_name":"Union Hospital, Tongji Medical College, Huazhong University of Science and Technology","has_results":false},{"nct_id":"NCT07126197","title":"Using Lymphovenous Bypass to Alleviate Diabetic Peripheral Neuropathy","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":60,"lead_sponsor_name":"National Taiwan University Hospital","has_results":false},{"nct_id":"NCT05766969","title":"Diabetic Neuropathic Pain Relief, 6 Weeks Dosage Sublingual Water-soluble CBD/PEA","phase":"PHASE1, PHASE2","overall_status":"UNKNOWN","enrollment_count":52,"lead_sponsor_name":"Pure Green Pharmaceuticals Inc.","has_results":false},{"nct_id":"NCT07061769","title":"Helping Cancer Patients Manage Neuropathy Symptoms From Chemotherapy With a Low-Intensity, Low-Risk Cranial PEMF Device","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":50,"lead_sponsor_name":"FluxWear, INC","has_results":false},{"nct_id":"NCT04679545","title":"Using Cannabidiol to Treat Diabetic Peripheral Neuropathy of the Feet","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":50,"lead_sponsor_name":"Pure Green","has_results":false},{"nct_id":"NCT03909841","title":"Neuropathic Pain in Elderly People With Diabetes: Impact on Quality of Life and Cognition","phase":"","overall_status":"COMPLETED","enrollment_count":48,"lead_sponsor_name":"Queen Elizabeth Hospital, Hong Kong","has_results":false},{"nct_id":"NCT03824860","title":"Yoga for Painful Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized-Controlled Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":47,"lead_sponsor_name":"Dana-Farber Cancer Institute","has_results":false},{"nct_id":"NCT04299893","title":"Ozone Therapy in Chemotherapy-induced Peripheral Neuropathy: RCT (O3NPIQ)","phase":"PHASE2, PHASE3","overall_status":"RECRUITING","enrollment_count":42,"lead_sponsor_name":"Bernardino Clavo, MD, PhD","has_results":false},{"nct_id":"NCT06964243","title":"Protocol Assessment of Motor Cortex rTMS for Treating Neuropathic Pain","phase":"NA","overall_status":"RECRUITING","enrollment_count":36,"lead_sponsor_name":"Institut pour la Pratique et l'Innovation en PSYchologie appliquée (Institut Pi-Psy)","has_results":false},{"nct_id":"NCT05349357","title":"Slider Versus Tensioner Neural Mobilization in Diabetic Peripheral Neuropathy","phase":"NA","overall_status":"COMPLETED","enrollment_count":32,"lead_sponsor_name":"Riphah International University","has_results":false},{"nct_id":"NCT06234917","title":"Increasing Sensori-Motor Rhythm Activity by EEG-Neurofeedback to Reduce the Impact of Pain on Daily Functioning","phase":"NA","overall_status":"COMPLETED","enrollment_count":32,"lead_sponsor_name":"Institut pour la Pratique et l'Innovation en PSYchologie appliquée (Institut Pi-Psy)","has_results":false},{"nct_id":"NCT05802511","title":"Study of Exablate Model 4000 Type 1.0/1.1 Following the Treatment of Neuropathic Pain","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"IRCCS Centro Neurolesi Bonino Pulejo","has_results":false},{"nct_id":"NCT07209514","title":"Medtronic Inceptiv™ Closed-Loop DTM Spinal Cord Stimulation for Painful Diabetic Peripheral Neuropathy","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":25,"lead_sponsor_name":"TriCity Research Center","has_results":false},{"nct_id":"NCT03191136","title":"Clinical Trial to Assess the Effect of Food on the Pharmacokinetics of YHD1119 in Healthy Volunteers","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":24,"lead_sponsor_name":"Yuhan Corporation","has_results":false},{"nct_id":"NCT04494815","title":"A Phase 1b Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SR419","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":24,"lead_sponsor_name":"Shanghai SIMR Biotechnology Co., Ltd.","has_results":false},{"nct_id":"NCT06361108","title":"MAD Study to Assess the Safety, Tolerability, PKs and Efficacy of YJ001 for Spray Use in Patients With DPNP","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":24,"lead_sponsor_name":"Zhejiang Hanmai Pharmaceutical Technology Co., Ltd.","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}