{"disease":{"id":"periodontal-bone-loss","name":"periodontal bone loss"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04702867","title":"Association Between Periodontal Bone Loss and Maxillary Sinus Changes.","phase":"","overall_status":"UNKNOWN","enrollment_count":450,"lead_sponsor_name":"Postgraduate Institute of Dental Sciences Rohtak","has_results":false},{"nct_id":"NCT04160689","title":"Influence of the Implant Connection on Facial Tissues Maturation","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":104,"lead_sponsor_name":"University of Milan","has_results":false},{"nct_id":"NCT07405918","title":"3D Printed Customized Bone Graft for Alveolar Regeneration: Longitudinal Cohort Evaluation","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":100,"lead_sponsor_name":"University of Guarulhos","has_results":false},{"nct_id":"NCT06727929","title":"The Effect of Non-surgical Periodontal Treatment on Dickkoff-1 and Secreted Frizzled Related Protein-5 Levels","phase":"","overall_status":"COMPLETED","enrollment_count":99,"lead_sponsor_name":"Cumhuriyet University","has_results":false},{"nct_id":"NCT05073575","title":"Application of Hyaluronic Acid in the Treatment of Periodontitis","phase":"NA","overall_status":"UNKNOWN","enrollment_count":80,"lead_sponsor_name":"Federico II University","has_results":false},{"nct_id":"NCT06809439","title":"Comparison of Saliva Biomarkers in Two Different Geographical Regions of Turkey","phase":"NA","overall_status":"COMPLETED","enrollment_count":77,"lead_sponsor_name":"Karabuk University","has_results":false},{"nct_id":"NCT05496608","title":"Treatment of Intrabony Defects With L-PRF Membrane With or Without Collagen Membranes","phase":"NA","overall_status":"COMPLETED","enrollment_count":63,"lead_sponsor_name":"Future University in Egypt","has_results":false},{"nct_id":"NCT03715374","title":"Platelet-Rich Fibrin and Anorganic Bovine Bone vs Collagen Membrane and Anorganic Bovine Bone in Intrabony Defects","phase":"NA","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"G. d'Annunzio University","has_results":false},{"nct_id":"NCT03978962","title":"Performance and Safety of the Resorbable Collagen Membrane \"Ez Cure\"","phase":"","overall_status":"COMPLETED","enrollment_count":56,"lead_sponsor_name":"Biomatlante","has_results":false},{"nct_id":"NCT03756493","title":"Added Benefit of L-PRF to Autogenous Bone Graft in the Treatment of Mandibular Degree II Furcation Defects","phase":"NA","overall_status":"COMPLETED","enrollment_count":54,"lead_sponsor_name":"G. d'Annunzio University","has_results":false},{"nct_id":"NCT03227367","title":"Osteoclast Impairment in Chronic Periodontitis by Regenerative Materials.","phase":"NA","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"Meenakshi Ammal Dental College and Hospital","has_results":false},{"nct_id":"NCT02972788","title":"Effect of Enamel Matrix Proteins on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients","phase":"EARLY_PHASE1","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"University of Nebraska","has_results":false},{"nct_id":"NCT07310732","title":"Clinical and Radiographic Assessment of Efficacy of Modified Minimally Invasive SurgicalTechnique (M-MIST) Alone and Combined With Enamel Matrix Proteins and Ox-derived Bone Graft in the Treatment of Single Bone Defects Between Teeth.","phase":"NA","overall_status":"COMPLETED","enrollment_count":45,"lead_sponsor_name":"Rungta College of Dental Sciences and Research","has_results":false},{"nct_id":"NCT06936605","title":"RGD With Minimally Invasive Non-Surgical Technique in Treatment of Periodontal Intrabony Defect","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":45,"lead_sponsor_name":"Minia University","has_results":false},{"nct_id":"NCT03510780","title":"Platelet-rich Fibrin and Autogenous Bone vs Enamel Matrix Derivative and Autogenous Bone in Intrabony Defects","phase":"NA","overall_status":"UNKNOWN","enrollment_count":44,"lead_sponsor_name":"G. d'Annunzio University","has_results":false},{"nct_id":"NCT04043754","title":"Platelet-rich Fibrin and Autogenous Bone vs Membrane and Autogenous Bone in Intrabony Defects","phase":"NA","overall_status":"COMPLETED","enrollment_count":44,"lead_sponsor_name":"G. d'Annunzio University","has_results":false},{"nct_id":"NCT03997578","title":"Non-incised Papillae Surgical Approach (NIPSA) and Connective Tissue Graft Plus Emdogain for Periodontal Defects","phase":"NA","overall_status":"RECRUITING","enrollment_count":40,"lead_sponsor_name":"Universidad de Murcia","has_results":false},{"nct_id":"NCT04827693","title":"The Cortical Shield for Facial Bone Reconstruction","phase":"","overall_status":"COMPLETED","enrollment_count":34,"lead_sponsor_name":"Verdugo, Fernando, DDS","has_results":false},{"nct_id":"NCT06925763","title":"Effect of Nitroglycerin Hydrogel on Repairing Critical Bone Defects","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":33,"lead_sponsor_name":"Minia University","has_results":false},{"nct_id":"NCT05766878","title":"The Rehabilitation of Atrophic Jaws Using Short Implants With Different Surface Characteristics","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"University of Foggia","has_results":false},{"nct_id":"NCT05119283","title":"Clinical Study of a Formulation Containing Phtalox® in Periodontal Disease","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Universidade Federal de Alfenas","has_results":false},{"nct_id":"NCT06318247","title":"Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets","phase":"NA","overall_status":"UNKNOWN","enrollment_count":30,"lead_sponsor_name":"The Dental Hospital of Zhejiang University School of Medicine","has_results":false},{"nct_id":"NCT04399135","title":"Accuracy of Pulp Sensibility Test on Teeth With Deep Periodontal Pocket","phase":"NA","overall_status":"UNKNOWN","enrollment_count":30,"lead_sponsor_name":"Qassim University","has_results":false},{"nct_id":"NCT07183631","title":"Healing of Intrabony Defects Following Treatment With PRF or EMD","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":28,"lead_sponsor_name":"Semmelweis University","has_results":false},{"nct_id":"NCT06798116","title":"Treatment of Periodontal Intrabony Defects With Liquid Platelet-Rich Fibrin Mixed With Denaturated Albumin Gel (ALB_PRF)","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":28,"lead_sponsor_name":"Mansoura University","has_results":false},{"nct_id":"NCT05360511","title":"Erythropoietin Gel as an Adjunct to Xenograft in the Surgical Management of Intrabony Periodontal Defects","phase":"EARLY_PHASE1","overall_status":"COMPLETED","enrollment_count":26,"lead_sponsor_name":"Ain Shams University","has_results":false},{"nct_id":"NCT05533528","title":"Periodontal Granulation Tissue Preservation in Surgical Periodontitis Treatment","phase":"NA","overall_status":"RECRUITING","enrollment_count":25,"lead_sponsor_name":"Universidad de Murcia","has_results":false},{"nct_id":"NCT03264118","title":"Effects of Antimicrobial Photodynamic Therapy on Regeneration of Class II Furcation Lesions","phase":"NA","overall_status":"COMPLETED","enrollment_count":25,"lead_sponsor_name":"University of Sao Paulo","has_results":false},{"nct_id":"NCT05315804","title":"Treatment of Intraosseous Periodontal Defects With Amelogenins","phase":"NA","overall_status":"UNKNOWN","enrollment_count":22,"lead_sponsor_name":"Federico II University","has_results":false},{"nct_id":"NCT05188898","title":"Treatment of Intraosseous Periodontal Defects With Hyaluronic Acid","phase":"NA","overall_status":"COMPLETED","enrollment_count":22,"lead_sponsor_name":"Federico II University","has_results":false},{"nct_id":"NCT06647186","title":"Evaluation of Non-Incised Papillae Surgical Approach (NIPSA) Versus Conventional Flap in Periodontal Reconstructive Surgery of Intrabony Defects (Clinical and Radiographic Study)","phase":"NA","overall_status":"COMPLETED","enrollment_count":20,"lead_sponsor_name":"Bassant Hamdy Mowafey","has_results":false},{"nct_id":"NCT06744348","title":"Entire Papilla Preservation Technique in the Treatment of Periodontal IntraBony Defects: a 1-year Follow-up Study","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":17,"lead_sponsor_name":"Necmettin Erbakan University","has_results":false},{"nct_id":"NCT07230522","title":"Effectiveness of Hyaluronic Acid (hyaDENT BG® Gel) Compared With Enamel Matrix Proteins (Emdogain®) in the Treatment of Angular Bone Defects in Combination With a Xenograft (Bio-Oss Collagen®)","phase":"NA","overall_status":"COMPLETED","enrollment_count":17,"lead_sponsor_name":"Medical University of Sofia","has_results":false},{"nct_id":"NCT07146776","title":"Treatment of Intrabony Defects With Injectable Platelet-Rich Fibrin and Xenogenic Grafts","phase":"NA","overall_status":"RECRUITING","enrollment_count":16,"lead_sponsor_name":"Saglik Bilimleri Universitesi","has_results":false},{"nct_id":"NCT07375004","title":"Injectable PRF in Non-Surgical Periodontal Treatment","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":13,"lead_sponsor_name":"Al-Mustansiriyah University","has_results":false},{"nct_id":"NCT05631600","title":"Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":12,"lead_sponsor_name":"University of Zagreb","has_results":false}],"total":36},"guidelines":[],"source":"Drug Landscape verified database"}