{"disease":{"id":"pci","name":"pci"},"drugs":{"marketed":[{"drug_id":"prasugrel","indication_name":"Acute Coronary Syndrome with PCI","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Effient","generic_name":"PRASUGREL","company_name":"Cosette","drug_phase":"marketed","molecular_target":"P2Y purinoceptor 12","drug_class":"P2Y12 Platelet Inhibitor","quality_score":80,"revenue":"400","mechanism":"Effient works by blocking the P2Y12 receptor on platelets, preventing them from aggregating and forming blood clots."},{"drug_id":"prasugrel","indication_name":"ST-Elevation Myocardial Infarction with PCI","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Effient","generic_name":"PRASUGREL","company_name":"Cosette","drug_phase":"marketed","molecular_target":"P2Y purinoceptor 12","drug_class":"P2Y12 Platelet Inhibitor","quality_score":80,"revenue":"400","mechanism":"Effient works by blocking the P2Y12 receptor on platelets, preventing them from aggregating and forming blood clots."}],"pipeline":[],"offLabel":[],"totalMarketed":2,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT07442500","title":"Drug Coated Balloon vs. Drug-eluting Stent in Patients With Coronary Artery Disease","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":470000,"lead_sponsor_name":"Samsung Medical Center","has_results":false},{"nct_id":"NCT07153744","title":"Efficacy and Safety of Shexiang Baoxin Pill(MUSKARDIA) in the Treatment of Acute Myocardial Infarction","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":9588,"lead_sponsor_name":"Shanghai Hutchison Pharmaceuticals Limited","has_results":false},{"nct_id":"NCT03510832","title":"Evaluation of Antithrombotic STrategies in STEMI Patients in China","phase":"","overall_status":"UNKNOWN","enrollment_count":8000,"lead_sponsor_name":"Qilu Hospital of Shandong University","has_results":false},{"nct_id":"NCT07361783","title":"Impact of Pre-Hospital Heparin Loading in STEMI Patients for Primary PCI: The HELP-PCI 2 Trial","phase":"NA","overall_status":"RECRUITING","enrollment_count":6294,"lead_sponsor_name":"Chen Jing","has_results":false},{"nct_id":"NCT03023020","title":"Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen","phase":"NA","overall_status":"COMPLETED","enrollment_count":4579,"lead_sponsor_name":"ECRI bv","has_results":false},{"nct_id":"NCT06648720","title":"Efficacy and Safety of Shortening Dual Antiplatelet Therapy Duration with IVUS Guidance in PCI Patients","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":3566,"lead_sponsor_name":"University Medical Center Ho Chi Minh City (UMC)","has_results":false},{"nct_id":"NCT07182799","title":"Starring Optical Coherence Tomography During Percutaneous Coronary Intervention Guidance","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":3200,"lead_sponsor_name":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","has_results":false},{"nct_id":"NCT06692140","title":"Comparison of an Ultra-low Strut Thickness Everolimus-eluting Biodegradable Polymer Stent Versus Durable Polymer Everolimus-eluting Stents in Patients Treated with Percutaneous Coronary Intervention","phase":"NA","overall_status":"RECRUITING","enrollment_count":3150,"lead_sponsor_name":"Odense University Hospital","has_results":false},{"nct_id":"NCT05955365","title":"Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":3010,"lead_sponsor_name":"Insel Gruppe AG, University Hospital Bern","has_results":false},{"nct_id":"NCT07231835","title":"Registry of Coronary Disease Outcomes Revascularizing With Drug-Coated Balloons","phase":"","overall_status":"RECRUITING","enrollment_count":3000,"lead_sponsor_name":"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","has_results":false},{"nct_id":"NCT06763744","title":"Genotype-Guided Abbreviated DAPT Versus Un-Guided De-escalation Therapy in Patients With ACS and HBR","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":3000,"lead_sponsor_name":"Samsung Medical Center","has_results":false},{"nct_id":"NCT04918030","title":"STaged Interventional Strategies for Acute ST-seGment Elevation Myocardial Infarction Patient With Multi-vessel Disease（STAGED）","phase":"NA","overall_status":"COMPLETED","enrollment_count":1586,"lead_sponsor_name":"Xiamen Cardiovascular Hospital, Xiamen University","has_results":false},{"nct_id":"NCT07297641","title":"Intravascular Imaging-Guided Versus Angiography- Guided PCI in Patients With DES-ISR","phase":"","overall_status":"RECRUITING","enrollment_count":1500,"lead_sponsor_name":"Nanjing First Hospital, Nanjing Medical University","has_results":false},{"nct_id":"NCT06910436","title":"Artificial Intelligence Based Timing, Infarct Size and Outcomes in Acute Coronary Occlusion Myocardial Infarction","phase":"","overall_status":"RECRUITING","enrollment_count":1500,"lead_sponsor_name":"Azienda Ospedaliera di Bolzano","has_results":false},{"nct_id":"NCT03479840","title":"Age-Dependent Impact of the SYNTAX-score on Mortality","phase":"","overall_status":"COMPLETED","enrollment_count":1331,"lead_sponsor_name":"LMU Klinikum","has_results":false},{"nct_id":"NCT05329155","title":"Early Administration of Heparin At FMC for PPCI of STEMI Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":1145,"lead_sponsor_name":"Renmin Hospital of Wuhan University","has_results":false},{"nct_id":"NCT07090382","title":"Prospective Validation of the STOPSHOCK Score - Artificial Intelligence Based Predictive Scoring System to Identify the Risk of Developing Cardiogenic Shock (CS) in Patients Suffering From Acute Coronary Syndrome (ACS)","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":1046,"lead_sponsor_name":"Premedix Academy","has_results":false},{"nct_id":"NCT06577519","title":"Efficacy and Safety Study of Vicagrel in Patients With Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Jiangsu vcare pharmaceutical technology co., LTD","has_results":false},{"nct_id":"NCT07273513","title":"\"Smart Family Doctor\" Assisted Comprehensive Management of Secondary Prevention Among Post Revascularization Patients","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":951,"lead_sponsor_name":"China National Center for Cardiovascular Diseases","has_results":false},{"nct_id":"NCT05466552","title":"The PROTECT-EU Study","phase":"","overall_status":"UNKNOWN","enrollment_count":859,"lead_sponsor_name":"Fondazione GISE Onlus","has_results":false},{"nct_id":"NCT06247982","title":"Bail-Out Stenting and Target-vessel Failure After Drug Coated Balloon Coronary percutaneouS Angioplasty for de Novo Lesions","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":800,"lead_sponsor_name":"IRCCS Azienda Ospedaliero-Universitaria di Bologna","has_results":false},{"nct_id":"NCT04500912","title":"Comparison of the Supraflex Cruz 60 Micron Versus the Ultimaster Tansei 80 Micron in HBR PCI Population","phase":"NA","overall_status":"COMPLETED","enrollment_count":736,"lead_sponsor_name":"Pieter C.Smits","has_results":false},{"nct_id":"NCT06690567","title":"Clinical Outcomes of Contemporary IMPELLA Devices in Cardiogenic Shock and High-risk Percutaneous Coronary Intervention","phase":"","overall_status":"UNKNOWN","enrollment_count":700,"lead_sponsor_name":"A.O.U. Città della Salute e della Scienza","has_results":false},{"nct_id":"NCT07491120","title":"The CDAC Study - Cerebral Dysfunction After Coronary Revascularization","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":600,"lead_sponsor_name":"The Scripps Research Institute","has_results":false},{"nct_id":"NCT06585917","title":"Comparison of 6F and 7F Sheaths for Coronary Intervention Via Distal Radial Artery Access","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":574,"lead_sponsor_name":"China National Center for Cardiovascular Diseases","has_results":false},{"nct_id":"NCT05605288","title":"Distal Versus Conventional Transradial Artery Access for Coronary Catheterization in Patients With STEMI","phase":"NA","overall_status":"RECRUITING","enrollment_count":554,"lead_sponsor_name":"University Hospital of Patras","has_results":false},{"nct_id":"NCT06615609","title":"\"Smart Family Doctor\" Assisted Comprehensive Management of Secondary Prevention Among Post Coronary Artery Bypass Graft Patients or Post Percutaneous Coronary Intervention Patients","phase":"NA","overall_status":"RECRUITING","enrollment_count":536,"lead_sponsor_name":"China National Center for Cardiovascular Diseases","has_results":false},{"nct_id":"NCT03058627","title":"Revascularization in Patients Undergoing Transcatheter Aortic Valve Implantation","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":454,"lead_sponsor_name":"Thomas Engstrom","has_results":false},{"nct_id":"NCT05388357","title":"AI Quantitative Coronary Angiography Versus Optical Coherent Tomography Guidance for Coronary Stent Implantation","phase":"NA","overall_status":"COMPLETED","enrollment_count":400,"lead_sponsor_name":"Asan Medical Center","has_results":false},{"nct_id":"NCT05820451","title":"Impella Real-World Surveillance of Patients Using Sodium Bicarbonate","phase":"","overall_status":"COMPLETED","enrollment_count":312,"lead_sponsor_name":"Abiomed Inc.","has_results":false},{"nct_id":"NCT06931574","title":"Double Kissing-crush vs Controlled Balloon-crush Techniques For Complex Coronary Bfurcation Lesions","phase":"","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Istanbul Mehmet Akif Ersoy Educational and Training Hospital","has_results":false},{"nct_id":"NCT03990948","title":"Hepcidin Behavior in Patients With Obesity and Bariatric Surgery","phase":"","overall_status":"TERMINATED","enrollment_count":300,"lead_sponsor_name":"Universitaire Ziekenhuizen KU Leuven","has_results":false},{"nct_id":"NCT07001332","title":"ELEVATE High-Risk PCI Pivotal Study","phase":"NA","overall_status":"RECRUITING","enrollment_count":290,"lead_sponsor_name":"Magenta Medical Ltd.","has_results":false},{"nct_id":"NCT07053618","title":"Interventional Left Ventricular Assist System for PCI in CHIP Patients","phase":"NA","overall_status":"RECRUITING","enrollment_count":286,"lead_sponsor_name":"Suzhou Hengruihongyuan Medical Technology Co. LTD","has_results":false},{"nct_id":"NCT06373120","title":"Interventional Ventricular Assist System for PCI in CHIP Patients","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":262,"lead_sponsor_name":"Shenzhen Core Medical Technology CO.,LTD.","has_results":false},{"nct_id":"NCT04651842","title":"Impact of Acute Insulin Resistance on Myocardial Blush in Non- Diabetic Patients Undergoing Primary Percutaneous Coronary Intervention","phase":"","overall_status":"COMPLETED","enrollment_count":240,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT07010965","title":"SAVE-PCI: NyokAssist™ Small-Bore VAD vs. IABP in Elective High-Risk PCI","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":236,"lead_sponsor_name":"magAssist, Inc.","has_results":false},{"nct_id":"NCT06853470","title":"Prospective Evaluation for Receiving SynFlow 3.0 Interventional Circulatory Support in High-risk PCI: A Randomized Controlled Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":222,"lead_sponsor_name":"ForQaly Medical (Shanghai) Co., Ltd","has_results":false},{"nct_id":"NCT03229993","title":"OCT in Borderline Coronary Artery Lesions","phase":"NA","overall_status":"COMPLETED","enrollment_count":220,"lead_sponsor_name":"The First Affiliated Hospital with Nanjing Medical University","has_results":false},{"nct_id":"NCT06992466","title":"Short Term Outcomes After Primary PCI in Diabetic Patients Treated With Insulin Versus Oral Anti-diabetic Drugs","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":210,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT06898021","title":"The 3D Stent Study","phase":"","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"CoreAalst BV","has_results":false},{"nct_id":"NCT03469856","title":"Acetyl Salicylic Elimination Trial: The ASET Pilot Study","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Pedro A. Lemos","has_results":false},{"nct_id":"NCT07442526","title":"AGECTO Study: PCI vs. Optimal Medical Therapy for CTO in the Octogenarian Patients","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":200,"lead_sponsor_name":"San Luigi Gonzaga Hospital","has_results":false},{"nct_id":"NCT06274411","title":"Standby Cannulated ECMO for High-Risk Percutaneous Coronary Intervention","phase":"NA","overall_status":"RECRUITING","enrollment_count":176,"lead_sponsor_name":"Beijing Anzhen Hospital","has_results":false},{"nct_id":"NCT03424941","title":"The TransCatheter Valve and Vessels Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":172,"lead_sponsor_name":"Maatschap Cardiologie Zwolle","has_results":false},{"nct_id":"NCT07140822","title":"A Randomized Study of Cutting Balloon Catheter for CAD","phase":"NA","overall_status":"COMPLETED","enrollment_count":166,"lead_sponsor_name":"Shanghai Shenqi Medical Technology Co., Ltd","has_results":false},{"nct_id":"NCT07123480","title":"The Role of 4 Different Consent Approaches on a Pilot Study to Increase Cardiac Rehabilitation Attendance","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":160,"lead_sponsor_name":"Baystate Medical Center","has_results":false},{"nct_id":"NCT07197242","title":"Prognostic Role of Lipoprotein(a) in Elective Percutaneous Coronary Revascularization","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":156,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT06710210","title":"Hybrid Percutaneous Coronary Intervention Combining a Bioresorbable Scaffold With Drug-coated Balloons Versus a Conventional Drug-eluting Stent-based Strategy in Patients With Long and Diffuse Coronary Artery Disease","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":150,"lead_sponsor_name":"University Hospital, Geneva","has_results":false},{"nct_id":"NCT06974760","title":"A Prospective, Multicenter, Blinded, Randomized Controlled Clinical Trial to Evaluate the Safety and Efficacy of IVUS Console and IVUS Catheter in Coronary Intervention Procedures","phase":"NA","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Pulse Medical Imaging Technology (Shanghai) Co., Ltd","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}