{"disease":{"id":"osteoarthritis-knee-pain","name":"osteoarthritis knee pain"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04490798","title":"Effectiveness of Acupuncture Clinical Pathway","phase":"","overall_status":"COMPLETED","enrollment_count":3245,"lead_sponsor_name":"Hospital Son Llatzer","has_results":false},{"nct_id":"NCT03670706","title":"Knee Pain Nurse Led Package of CareTrial","phase":"NA","overall_status":"COMPLETED","enrollment_count":1806,"lead_sponsor_name":"University of Nottingham","has_results":false},{"nct_id":"NCT06477965","title":"Embo Registry; National Registry for Artery Embolization","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Vascular Solutions of North Carolina","has_results":false},{"nct_id":"NCT06124170","title":"Improved Pain Management in Knee Osteoarthritis-related Surgeries","phase":"","overall_status":"COMPLETED","enrollment_count":714,"lead_sponsor_name":"Peng Liu","has_results":false},{"nct_id":"NCT00973141","title":"A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Osteoarthritis-related Pain","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":467,"lead_sponsor_name":"Johnson & Johnson Pharmaceutical Research & Development, L.L.C.","has_results":false},{"nct_id":"NCT03364088","title":"Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia","phase":"NA","overall_status":"COMPLETED","enrollment_count":402,"lead_sponsor_name":"Riku Antero Palanne","has_results":false},{"nct_id":"NCT04077164","title":"Chronic Pain, Couples, & Physical Activity","phase":"","overall_status":"TERMINATED","enrollment_count":400,"lead_sponsor_name":"Illinois Institute of Technology","has_results":false},{"nct_id":"NCT05407610","title":"Comparison of Conventional and Cooled Radiofrequency of the Genicular Nerves in Patients With Chronic Knee Pain","phase":"NA","overall_status":"RECRUITING","enrollment_count":400,"lead_sponsor_name":"Ziekenhuis Oost-Limburg","has_results":false},{"nct_id":"NCT06086483","title":"Pain Management After Adductor Canal Block for Total Knee Arthroplasty","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":361,"lead_sponsor_name":"Poznan University of Medical Sciences","has_results":false},{"nct_id":"NCT06087562","title":"iPACK Block for Total Knee Arthroplasty","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":350,"lead_sponsor_name":"Poznan University of Medical Sciences","has_results":false},{"nct_id":"NCT03434197","title":"Safety and Efficacy of SFPP in Knee Osteoarthritis","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":313,"lead_sponsor_name":"Taisho Pharmaceutical Co., Ltd.","has_results":false},{"nct_id":"NCT07308873","title":"Individual Differences in Gait and Osteoarthritis Pain","phase":"","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"University of Pittsburgh","has_results":false},{"nct_id":"NCT04497129","title":"ROMTECH PortableConnect Rehabilitation Device Usage Post Unilateral Total Knee Arthroplasty (TKA)","phase":"NA","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"ROM Technologies, INC","has_results":false},{"nct_id":"NCT00399490","title":"Open-label Extension Study Of RN624","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":287,"lead_sponsor_name":"Pfizer","has_results":true},{"nct_id":"NCT03211663","title":"Performance of MOTO Medial® Unicompartmental Knee Arthroplasty","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":269,"lead_sponsor_name":"Medacta USA","has_results":false},{"nct_id":"NCT03956550","title":"A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":259,"lead_sponsor_name":"Regeneron Pharmaceuticals","has_results":true},{"nct_id":"NCT05652270","title":"Maximizing Patient Goal Attainment","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":258,"lead_sponsor_name":"Dartmouth-Hitchcock Medical Center","has_results":false},{"nct_id":"NCT03815448","title":"Methotrexate in the Treatment of Advanced Knee Osteoarthritis With Effusion-synovitis","phase":"NA","overall_status":"COMPLETED","enrollment_count":215,"lead_sponsor_name":"Zhujiang Hospital","has_results":false},{"nct_id":"NCT02611466","title":"A Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the Knee","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":215,"lead_sponsor_name":"Astellas Pharma Europe B.V.","has_results":false},{"nct_id":"NCT05975879","title":"A Study of the Feasibility of Using the Dietary Supplement \"ARTNEO\" in Patients With Osteoathritis","phase":"NA","overall_status":"COMPLETED","enrollment_count":212,"lead_sponsor_name":"NPO Petrovax","has_results":false},{"nct_id":"NCT07134283","title":"Effect of Preoperative Cold Therapy on Early Postoperative Outcomes in Total Knee Arthroplasty","phase":"NA","overall_status":"COMPLETED","enrollment_count":208,"lead_sponsor_name":"Ankara City Hospital Bilkent","has_results":false},{"nct_id":"NCT01094262","title":"A Safety and Tolerability Study of JNJ-42160443 in Patients With Moderate to Severe, Chronic Knee Pain From Osteoarthritis","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":196,"lead_sponsor_name":"Johnson & Johnson Pharmaceutical Research & Development, L.L.C.","has_results":false},{"nct_id":"NCT03182686","title":"AP-003-C Study to Confirm the Efficacy of Ampion™ in Adults With Pain Due to Severe Osteoarthritis of the Knee","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":168,"lead_sponsor_name":"Ampio Pharmaceuticals. Inc.","has_results":true},{"nct_id":"NCT03538470","title":"Assessment of the Effect of Spa Treatment on Rheumatological Conditions","phase":"NA","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"SAEML Contrexéville","has_results":false},{"nct_id":"NCT07430085","title":"Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":150,"lead_sponsor_name":"Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)","has_results":false},{"nct_id":"NCT07226258","title":"Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":150,"lead_sponsor_name":"Saol Therapeutics Inc","has_results":false},{"nct_id":"NCT04117893","title":"Duloxetine Combined With Intra-articular Injection of Corticosteroid and Hyaluronic Acid Reduces Pain in the Treatment of Knee Osteoarthritis Patients","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT04207021","title":"Effectiveness of Curcumin-based Food Supplement in Reducing Pain and Inflammatory Component in Osteoarthritis","phase":"NA","overall_status":"UNKNOWN","enrollment_count":134,"lead_sponsor_name":"KOS Care SRL - Istituto di Riabilitazione Santo Stefano","has_results":false},{"nct_id":"NCT05871112","title":"Femoral Rotation and Patellar Positioning After TKA","phase":"","overall_status":"COMPLETED","enrollment_count":125,"lead_sponsor_name":"Medical University of Warsaw","has_results":false},{"nct_id":"NCT03528369","title":"A Phase 2 Clinical Trial Examining the Effects on Osteoarthritic Knee Pain of CGS-200-1, CGS-200-5 and Vehicle Control","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":122,"lead_sponsor_name":"Propella Therapeutics","has_results":true},{"nct_id":"NCT05700682","title":"Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee","phase":"","overall_status":"RECRUITING","enrollment_count":120,"lead_sponsor_name":"Palo Alto Veterans Institute for Research","has_results":false},{"nct_id":"NCT03336099","title":"Assessment of the Effect of Spa Treatment on the Functional Severity of Arthrosis","phase":"NA","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"Le Syndicat Intercommunal pour le Thermalisme et l'Environnement","has_results":false},{"nct_id":"NCT06880926","title":"Antarctic Krill Oil for Knee Osteoarthritis Pain","phase":"PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":116,"lead_sponsor_name":"Qilu Hospital of Shandong University","has_results":false},{"nct_id":"NCT03545048","title":"Effects of Internet / Web-based Exercises on the Population With Knee Arthritis","phase":"NA","overall_status":"COMPLETED","enrollment_count":105,"lead_sponsor_name":"University of Nottingham","has_results":false},{"nct_id":"NCT03117231","title":"Effects of tDCS in Elderly With Pain Due to Knee Osteoarthritis","phase":"NA","overall_status":"COMPLETED","enrollment_count":104,"lead_sponsor_name":"Federal University of São Paulo","has_results":false},{"nct_id":"NCT04814082","title":"Prospective Functional, Gait, and Outcome Comparison Study of Medial Pivot Versus Single Radius Design for Total Knee Arthroplasty","phase":"NA","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"LifeBridge Health","has_results":false},{"nct_id":"NCT07425457","title":"Cryoneurolysis Prior to Total Knee Arthroplasty (CRYO-TKA Trial)","phase":"NA","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"Attikon Hospital","has_results":false},{"nct_id":"NCT03542838","title":"Study of Resiniferatoxin for Knee Pain in Moderate to Severe Osteoarthritis","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":94,"lead_sponsor_name":"Sorrento Therapeutics, Inc.","has_results":false},{"nct_id":"NCT05079035","title":"Lyophilized and Micronized Particulate Human Amniotic and Umbilical Cord (TTAX03) for KL Grade 3-4 Knee OA","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"BioTissue Holdings, Inc","has_results":false},{"nct_id":"NCT06470100","title":"Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Poznan University of Medical Sciences","has_results":false},{"nct_id":"NCT06233630","title":"Erector Spinae Plane Block Vs. IPACK Block with Adductor Canal Block for Total Knee Arthroplasty","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Poznan University of Medical Sciences","has_results":false},{"nct_id":"NCT05656014","title":"The Relationship of the Medial Longitudinal Arch Height With Clinical Features of Knee Osteoarthritis","phase":"","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Gazi University","has_results":false},{"nct_id":"NCT07180953","title":"Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":90,"lead_sponsor_name":"Poznan University of Medical Sciences","has_results":false},{"nct_id":"NCT05211544","title":"The Effect of Physical Therapy Modalities and Kinesio Taping in Patients With Knee Osteoarthritis","phase":"NA","overall_status":"UNKNOWN","enrollment_count":90,"lead_sponsor_name":"Abant Izzet Baysal University","has_results":false},{"nct_id":"NCT05930756","title":"3-point vs 6-point GNRFA for Chronic KOA","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":80,"lead_sponsor_name":"McMaster University","has_results":false},{"nct_id":"NCT05548712","title":"The Effect of PEMF for Patients With Knee OA","phase":"NA","overall_status":"UNKNOWN","enrollment_count":80,"lead_sponsor_name":"Chinese University of Hong Kong","has_results":false},{"nct_id":"NCT03334903","title":"Gabapentin Regimens and Their Effects on Opioid Consumption","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":77,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":true},{"nct_id":"NCT04588558","title":"Investigation of the Effectiveness of a Structured Squat-based Program in Knee Osteoarthritis Rehabilitation","phase":"NA","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Istanbul Medipol University Hospital","has_results":false},{"nct_id":"NCT06936709","title":"Perioperative Colchicine for TKA","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":75,"lead_sponsor_name":"Geisinger Clinic","has_results":false},{"nct_id":"NCT04443452","title":"Molecular Pathways Involved in Knee Pain","phase":"","overall_status":"COMPLETED","enrollment_count":71,"lead_sponsor_name":"University of Nottingham","has_results":true}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}