{"disease":{"id":"open-angle-glaucoma-ocular-hypertension","name":"open angle glaucoma ocular hypertension"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT02558400","title":"Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":718,"lead_sponsor_name":"Aerie Pharmaceuticals","has_results":true},{"nct_id":"NCT03395535","title":"Laser-1st vs Drops-1st for Glaucoma and Ocular Hypertension","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":718,"lead_sponsor_name":"Moorfields Eye Hospital NHS Foundation Trust","has_results":false},{"nct_id":"NCT04630808","title":"MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":696,"lead_sponsor_name":"Nicox Ophthalmics, Inc.","has_results":false},{"nct_id":"NCT04445519","title":"Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":691,"lead_sponsor_name":"Nicox Ophthalmics, Inc.","has_results":true},{"nct_id":"NCT03450629","title":"Evaluation of Safety and Efficacy of PDP-716","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":682,"lead_sponsor_name":"Sun Pharma Advanced Research Company Limited","has_results":true},{"nct_id":"NCT01026831","title":"Preservative-Free MK2452 (Tafluprost) for Open-Angle Glaucoma/Ocular Hypertension (MK2452-001)(COMPLETED)","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":643,"lead_sponsor_name":"Merck Sharp & Dohme LLC","has_results":true},{"nct_id":"NCT05022004","title":"A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":599,"lead_sponsor_name":"Sun Pharmaceutical Industries Limited","has_results":true},{"nct_id":"NCT02914509","title":"Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":565,"lead_sponsor_name":"Ocular Therapeutix, Inc.","has_results":true},{"nct_id":"NCT03850782","title":"Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":515,"lead_sponsor_name":"AbbVie","has_results":false},{"nct_id":"NCT02339584","title":"Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":493,"lead_sponsor_name":"Alcon Research","has_results":true},{"nct_id":"NCT03284853","title":"Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":436,"lead_sponsor_name":"Aerie Pharmaceuticals","has_results":true},{"nct_id":"NCT06441643","title":"Next Generation Rocklatan","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":426,"lead_sponsor_name":"Alcon Research","has_results":false},{"nct_id":"NCT01749904","title":"Comparing Safety and Efficacy of BOL-303259-X With Timolol Maleate in Subjects With Open-Angle Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":420,"lead_sponsor_name":"Bausch & Lomb Incorporated","has_results":true},{"nct_id":"NCT05181046","title":"Evaluation of Nanodropper-mediated Microdrops vs. Standard Drops of 0.5% Timolol Maleate in Glaucoma Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":420,"lead_sponsor_name":"Nanodropper, Inc.","has_results":false},{"nct_id":"NCT05159960","title":"Optimal Treatment Protocol for Selective Laser Trabeculoplasty - Repeat Trial","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":400,"lead_sponsor_name":"Vastra Gotaland Region","has_results":false},{"nct_id":"NCT03798223","title":"Optimal Treatment Protocol for Selective Laser Trabeculoplasty","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":400,"lead_sponsor_name":"Vastra Gotaland Region","has_results":false},{"nct_id":"NCT04133311","title":"A Phase III Multinational Multicenter Investigator-Masked Randomized Active-Controlled Trial Comparing the Efficacy and Safety of DE-130A With Xalatan® in Patients With Open-Angle Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":386,"lead_sponsor_name":"Santen SAS","has_results":true},{"nct_id":"NCT03762369","title":"A Clinical Study to Evaluate the Efficacy and Safety of CKD-351","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":384,"lead_sponsor_name":"Chong Kun Dang Pharmaceutical","has_results":false},{"nct_id":"NCT02617459","title":"Levobetaxolol Hydrochloride Eye Drops for Treatment of Primary Open-angle Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":366,"lead_sponsor_name":"Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.","has_results":false},{"nct_id":"NCT06666855","title":"A Phase III Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension in China","phase":"PHASE3","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":345,"lead_sponsor_name":"Santen Pharmaceutical Co., Ltd.","has_results":false},{"nct_id":"NCT05495061","title":"A Comparative Confirmatory Study of STN1012600 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":325,"lead_sponsor_name":"Santen Pharmaceutical Co., Ltd.","has_results":false},{"nct_id":"NCT04742283","title":"Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":323,"lead_sponsor_name":"Santen Inc.","has_results":true},{"nct_id":"NCT00572455","title":"Safety and Efficacy of PF-04217329 in Patients With Glaucoma or Elevated Eye Pressure.","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":318,"lead_sponsor_name":"Pfizer","has_results":true},{"nct_id":"NCT02419508","title":"SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":290,"lead_sponsor_name":"Alcon Research","has_results":true},{"nct_id":"NCT02623738","title":"A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study-","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":253,"lead_sponsor_name":"Santen Pharmaceutical Co., Ltd.","has_results":false},{"nct_id":"NCT04620135","title":"Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Japanese Subjects With Primary Open Angle Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":245,"lead_sponsor_name":"Aerie Pharmaceuticals","has_results":true},{"nct_id":"NCT03216902","title":"A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel Study","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":241,"lead_sponsor_name":"Santen Inc.","has_results":true},{"nct_id":"NCT06267274","title":"A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":240,"lead_sponsor_name":"Amneal Pharmaceuticals, LLC","has_results":false},{"nct_id":"NCT01068964","title":"Safety and Efficacy of Bimatoprost Timolol Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension","phase":"NA","overall_status":"COMPLETED","enrollment_count":235,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT04910100","title":"Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular Hypertension","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":226,"lead_sponsor_name":"Betaliq, Inc.","has_results":true},{"nct_id":"NCT04647214","title":"18 Month Prospective Efficacy and Safety Study of Bimatoprost Intracameral Implant (DURYSTA)","phase":"","overall_status":"COMPLETED","enrollment_count":220,"lead_sponsor_name":"Allergan","has_results":false},{"nct_id":"NCT03822559","title":"A Study of DE-111A on the Treatment of Open Angle Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":219,"lead_sponsor_name":"Santen Pharmaceutical Co., Ltd.","has_results":false},{"nct_id":"NCT03844945","title":"Efficacy and Systemic Safety of Netarsudil 0.01%, 0.02%, 0.04% Relative to Placebo in Subjects With Open-angle Glaucoma or Ocular Hypertension in Japan","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":215,"lead_sponsor_name":"Aerie Pharmaceuticals","has_results":true},{"nct_id":"NCT05583474","title":"OPC-1085EL in the Treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Chinese Subjects","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":204,"lead_sponsor_name":"Otsuka Beijing Research Institute","has_results":false},{"nct_id":"NCT03750201","title":"A Study to Assess an Automated Laser Device for Direct Selective Laser Trabeculoplasty","phase":"NA","overall_status":"COMPLETED","enrollment_count":201,"lead_sponsor_name":"BelkinVision","has_results":false},{"nct_id":"NCT02829996","title":"Study of Fixed-Dose Combinations of Trabodenoson and Latanoprost in Adults With OHT or POAG","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":201,"lead_sponsor_name":"Inotek Pharmaceuticals Corporation","has_results":true},{"nct_id":"NCT02730871","title":"Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV®","phase":"PHASE4","overall_status":"TERMINATED","enrollment_count":173,"lead_sponsor_name":"Alcon Research","has_results":true},{"nct_id":"NCT01915940","title":"Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular Hypertension","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":169,"lead_sponsor_name":"ForSight Vision5, Inc.","has_results":true},{"nct_id":"NCT02358369","title":"Dose-Ranging Study of the Bimatoprost Ocular Insert","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":156,"lead_sponsor_name":"ForSight Vision5, Inc.","has_results":true},{"nct_id":"NCT05279716","title":"Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag Isopropyl","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"Santen Pharmaceutical Asia Pte. Ltd.","has_results":false},{"nct_id":"NCT03419975","title":"A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Efficacy and Safety of TJO-002 in POAG or Ocular Hypertension Patients","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":146,"lead_sponsor_name":"Taejoon Pharmaceutical Co., Ltd.","has_results":false},{"nct_id":"NCT05503901","title":"A Long Term Study of STN1012600 in Subjects With Open Angle Glaucoma or Ocular Hypertension","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":131,"lead_sponsor_name":"Santen Pharmaceutical Co., Ltd.","has_results":false},{"nct_id":"NCT06498440","title":"Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCT","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":126,"lead_sponsor_name":"St. Joseph's Healthcare Hamilton","has_results":false},{"nct_id":"NCT02822729","title":"A Long-term Study of DE-117 Ophthalmic Solution Monotherapy and Concomitant Use of DE-117 Ophthalmic Solution With Timolol Ophthalmic Solution in Patients With OAG or OH: RENGE Study","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":125,"lead_sponsor_name":"Santen Pharmaceutical Co., Ltd.","has_results":false},{"nct_id":"NCT01157364","title":"Safety and Efficacy of a New Ophthalmic Formulation of Bimatoprost in Patients With Open Angle Glaucoma and Ocular Hypertension","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":109,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT03697811","title":"DE-117 Spectrum 5 Study","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":107,"lead_sponsor_name":"Santen Inc.","has_results":true},{"nct_id":"NCT04595227","title":"Glaucoma Screening Using Dynamic Analysis of Computerized Pupillary Light Reflex Assessment Device","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Peking University","has_results":false},{"nct_id":"NCT04448223","title":"A Clinical Study to Evaluate the Efficacy and Safety of CKD-351","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Chong Kun Dang Pharmaceutical","has_results":false},{"nct_id":"NCT03858894","title":"Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Once Daily and Twice Daily in Subjects With Primary Open-Angle Glaucoma SPECTRUM 6","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":98,"lead_sponsor_name":"Santen Inc.","has_results":true},{"nct_id":"NCT03534882","title":"Effects of Prostaglandin Analogue Washout Following Long-term Therapy in Adults With Primary Open Angle Glaucoma","phase":"NA","overall_status":"COMPLETED","enrollment_count":87,"lead_sponsor_name":"Cindy Hutnik","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}