{"disease":{"id":"non-union-fracture","name":"non union fracture"},"drugs":{"marketed":[{"drug_id":"eptotermin-alfa","indication_name":"Nonunion of fracture","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Osigraft","generic_name":"EPTOTERMIN ALFA","company_name":"Olympus Biotech International Limited","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":13,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05163795","title":"Distal Femur Fracture Nonunion - Statistical Analysis Plan","phase":"","overall_status":"COMPLETED","enrollment_count":299,"lead_sponsor_name":"Töölö Hospital","has_results":false},{"nct_id":"NCT02783274","title":"Actis Total Hip System 2 Year Follow-up","phase":"NA","overall_status":"COMPLETED","enrollment_count":266,"lead_sponsor_name":"DePuy Orthopaedics","has_results":true},{"nct_id":"NCT04299022","title":"Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care","phase":"","overall_status":"RECRUITING","enrollment_count":250,"lead_sponsor_name":"LifeNet Health","has_results":false},{"nct_id":"NCT06652659","title":"Risk Factors for Development of Non-union of Displaced Midshaft Clavicle Fractures","phase":"","overall_status":"RECRUITING","enrollment_count":250,"lead_sponsor_name":"Bispebjerg Hospital","has_results":false},{"nct_id":"NCT03928912","title":"Risk Factors for Post-Operative Nonunion of Tibial Shaft Fractures Based on a Path Analysis Model","phase":"","overall_status":"COMPLETED","enrollment_count":234,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT05703958","title":"Exactech Proximal Humerus Fracture Plate System Post Market Clinical Follow-up","phase":"","overall_status":"RECRUITING","enrollment_count":151,"lead_sponsor_name":"Exactech","has_results":false},{"nct_id":"NCT00208442","title":"A Randomised Single Centre Study to Compare the Long-term Wear Characteristics of Marathon™ and Enduron™ Polyethylene Cup Liners in Primary Total Hip Replacement","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":122,"lead_sponsor_name":"DePuy International","has_results":false},{"nct_id":"NCT03937310","title":"NGS for Non-unions","phase":"","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"Rothman Institute Orthopaedics","has_results":false},{"nct_id":"NCT04564625","title":"Relationships Between Vitamin D and Orthopedic Trauma","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Methodist Health System","has_results":false},{"nct_id":"NCT05613257","title":"Distal Targeter vs Free-hand","phase":"NA","overall_status":"COMPLETED","enrollment_count":89,"lead_sponsor_name":"Cedars-Sinai Medical Center","has_results":true},{"nct_id":"NCT04945434","title":"Clinical Effectiveness of S53P4 Bioactive Glass in Treatment of Long-bone Chronic Osteomyelitis","phase":"NA","overall_status":"UNKNOWN","enrollment_count":78,"lead_sponsor_name":"Academisch Ziekenhuis Maastricht","has_results":false},{"nct_id":"NCT03325504","title":"A Comparative Study of 2 Doses of BM Autologous H-MSC+Biomaterial vs Iliac Crest AutoGraft for Bone Healing in Non-Union","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":46,"lead_sponsor_name":"Universidad Autonoma de Madrid","has_results":false},{"nct_id":"NCT06103396","title":"Treatment of Nonunion Fractures With Mesenchymal Stromal Cells (MSCs)","phase":"PHASE1, PHASE2","overall_status":"UNKNOWN","enrollment_count":30,"lead_sponsor_name":"Instituto Venezolano de Investigaciones Cientificas","has_results":false},{"nct_id":"NCT07039695","title":"Union Rate of Scaphoid Non-Union Fracture in Adults by Herbert Screw Versus Volar Buttress Plate","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Helwan University","has_results":false},{"nct_id":"NCT06005090","title":"Is Far Cortical Locking More Effective Than Bicortical Locking in Treating AO 43A1-3 Fractures?","phase":"","overall_status":"COMPLETED","enrollment_count":26,"lead_sponsor_name":"Saglik Bilimleri Universitesi","has_results":false},{"nct_id":"NCT04705857","title":"Comparative Study of Gene-activated Bone Substitute and Autobone in Treatment of Long Bone Nonunions","phase":"","overall_status":"UNKNOWN","enrollment_count":20,"lead_sponsor_name":"Histograft Co., Ltd.","has_results":false},{"nct_id":"NCT02230514","title":"Mesenchymal Stromal Cells for the Treatment of Non-union Fractures of Long Bones","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":19,"lead_sponsor_name":"Banc de Sang i Teixits","has_results":false},{"nct_id":"NCT04340284","title":"Adipose Tissue Derived Stromal Vascular Fraction (SVF) Application in Treatment of Long Bones Nonunion","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":11,"lead_sponsor_name":"Dr. Himanshu Bansal Foundation","has_results":false},{"nct_id":"NCT00872573","title":"A Two Centre Study to Assess the Stability and Long-term Performance of the C-Stem™ AMT in a Total Primary Hip Replacement","phase":"PHASE4","overall_status":"TERMINATED","enrollment_count":5,"lead_sponsor_name":"DePuy International","has_results":false},{"nct_id":"NCT06400732","title":"Post Market Evaluation of Clinical Safety and Performance of the Fitbone Transport and Lengthening System","phase":"","overall_status":"TERMINATED","enrollment_count":1,"lead_sponsor_name":"Orthofix Inc.","has_results":false},{"nct_id":"NCT00208429","title":"A Multi-centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Polyethylene-on-metal Bearing in Primary Total Hip Replacement","phase":"PHASE4","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"DePuy International","has_results":false}],"total":21},"guidelines":[],"source":"Drug Landscape verified database"}