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Patients with EGFR or ALK genomic tumor aberrations should have disease progression on FDA-approved therapy for these aberrations prior to receiving OPDIVO QVANTIG.","line_of_therapy":"2L","evidence_grade":"not specified","guideline_year":null},{"drug_id":"atezolizumab","guideline_body":"FDA label","recommendation":"TECENTRIQ is indicated as adjuvant treatment following resection and platinum-based chemotherapy for adult patients with Stage II to IIIA NSCLC whose tumors have PD-L1 expression on ≥ 1% of tumor cells, as determined by an FDA-approved test.","line_of_therapy":"adjuvant","evidence_grade":"Not specified","guideline_year":null},{"drug_id":"atezolizumab","guideline_body":"FDA label","recommendation":"TECENTRIQ is indicated for the first-line treatment of adult patients with metastatic NSCLC whose tumors have high PD-L1 expression (PD-L1 stained ≥ 50% of tumor cells [TC ≥ 50%] or PD-L1 stained tumor-infiltrating immune cells [IC] covering ≥ 10% of the tumor area [IC ≥ 10%]), as determined by an FDA-approved test, with no EGFR or ALK genomic tumor aberrations.","line_of_therapy":"1L","evidence_grade":"Not specified","guideline_year":null},{"drug_id":"atezolizumab","guideline_body":"FDA label","recommendation":"TECENTRIQ is indicated in combination with bevacizumab, paclitaxel, and carboplatin for the first-line treatment of adult patients with metastatic non-squamous NSCLC with no EGFR or ALK genomic tumor aberrations.","line_of_therapy":"1L","evidence_grade":"Not specified","guideline_year":null},{"drug_id":"atezolizumab","guideline_body":"FDA label","recommendation":"TECENTRIQ is indicated in combination with paclitaxel protein-bound and carboplatin for the first-line treatment of adult patients with metastatic non-squamous NSCLC with no EGFR or ALK genomic tumor aberrations.","line_of_therapy":"1L","evidence_grade":"Not specified","guideline_year":null},{"drug_id":"atezolizumab","guideline_body":"FDA label","recommendation":"TECENTRIQ is indicated for the treatment of adult patients with metastatic NSCLC who have disease progression during or following platinum-containing chemotherapy. Patients with EGFR or ALK genomic tumor aberrations should have disease progression on FDA-approved therapy for NSCLC harboring these aberrations prior to receiving TECENTRIQ.","line_of_therapy":"2L","evidence_grade":"Not specified","guideline_year":null},{"drug_id":"atezolizumab","guideline_body":"FDA label","recommendation":"TECENTRIQ is indicated in combination with bevacizumab for the treatment of adult patients with unresectable or metastatic HCC who have not received prior systemic therapy.","line_of_therapy":"1L","evidence_grade":"Not specified","guideline_year":null},{"drug_id":"atezolizumab","guideline_body":"FDA label","recommendation":"TECENTRIQ is indicated for the treatment of adult and pediatric patients 2 years of age and older with unresectable or metastatic ASPS.","line_of_therapy":"1L","evidence_grade":"Not specified","guideline_year":null}],"source":"Drug Landscape verified database"}