{"disease":{"id":"non-response","name":"non response"},"drugs":{"marketed":[{"drug_id":"upadacitinib","indication_name":"Active non-radiographic axial spondyloarthritis with objective signs of inflammation in adults with inadequate response or intolerance to TNF blockers","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Rinvoq","generic_name":"upadacitinib","company_name":"AbbVie Inc.","drug_phase":"marketed","molecular_target":"Janus kinase (JAK) enzymes, particularly JAK1 and JAK2","drug_class":"JAK inhibitor","quality_score":86,"revenue":"5300","mechanism":"JAK inhibitor that prevents STAT phosphorylation and activation in cytokine signaling pathways."}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05520242","title":"Use of Animations Movies to Increase Response in a National Health Survey","phase":"NA","overall_status":"COMPLETED","enrollment_count":201200,"lead_sponsor_name":"University of Southern Denmark","has_results":false},{"nct_id":"NCT07319065","title":"Left Ventricular Myocardial Work for Predicting Response to CRT","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":3240,"lead_sponsor_name":"First Hospital of China Medical University","has_results":false},{"nct_id":"NCT07178483","title":"Evaluation of Physical Capacity and Energy Requirements in Patients With Hypoxemic Acute Respiratory Failure","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":500,"lead_sponsor_name":"Hospital Universitari de Bellvitge","has_results":false},{"nct_id":"NCT04573543","title":"The Role of Immune Semaphorins in NAFLD","phase":"","overall_status":"COMPLETED","enrollment_count":160,"lead_sponsor_name":"University Hospital for Infectious Diseases, Croatia","has_results":false},{"nct_id":"NCT06443606","title":"Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":108,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT06231862","title":"Gene Expression Objective Definition of Early Sepsis In Children","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"Seattle Children's Hospital","has_results":false},{"nct_id":"NCT05925751","title":"Deep Learning Signature for Predicting Complete Pathological Response to Neoadjuvant Chemoimmunotherapy in Non-small Cell Lung Cancer","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Shanghai Pulmonary Hospital, Shanghai, China","has_results":false},{"nct_id":"NCT05884411","title":"Evaluation of Left Bundle Branch Area Pacing As A Rescue Strategy for Cardiac Resynchronization Therapy Non-Response","phase":"NA","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"VA Office of Research and Development","has_results":false}],"total":8},"guidelines":[],"source":"Drug Landscape verified database"}