{"disease":{"id":"nicotine-use","name":"nicotine use"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03194958","title":"Helping Poor Smokers Quit","phase":"NA","overall_status":"COMPLETED","enrollment_count":1944,"lead_sponsor_name":"Washington University School of Medicine","has_results":true},{"nct_id":"NCT05515354","title":"Smoking Cessation and Menstrual Cycle Phase","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":1200,"lead_sponsor_name":"Centre for Addiction and Mental Health","has_results":false},{"nct_id":"NCT06553196","title":"MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience Education","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":1000,"lead_sponsor_name":"California State University, Northridge","has_results":false},{"nct_id":"NCT04974580","title":"Research and Innovation to Stop E-cigarette/Vaping in Young Adults","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":508,"lead_sponsor_name":"Ohio State University","has_results":true},{"nct_id":"NCT04946825","title":"Quit Smoking Study for People Who Use E-Cigarettes","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":396,"lead_sponsor_name":"University of Vermont","has_results":true},{"nct_id":"NCT07123389","title":"Family and Peer Influences on Nicotine Dependence in Medical Students of South Punjab","phase":"","overall_status":"COMPLETED","enrollment_count":366,"lead_sponsor_name":"Nishtar Medical University","has_results":false},{"nct_id":"NCT03506867","title":"Healthy People Initiative (HPI)","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":250,"lead_sponsor_name":"Ottawa Hospital Research Institute","has_results":false},{"nct_id":"NCT01036711","title":"Effects of Nicotine on Cognitive Task Performance and Brain Activity as Measured by fMRI","phase":"","overall_status":"COMPLETED","enrollment_count":249,"lead_sponsor_name":"National Institute on Drug Abuse (NIDA)","has_results":false},{"nct_id":"NCT05206435","title":"Methadone-Maintained Smokers Switching to E-Cigarettes","phase":"PHASE4","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":240,"lead_sponsor_name":"Butler Hospital","has_results":false},{"nct_id":"NCT05181891","title":"Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":205,"lead_sponsor_name":"Washington State University","has_results":false},{"nct_id":"NCT07366294","title":"Lemongrass (Cymbopogon Citratus) on Nicotine Dependence, Cotinine Levels, and Related Biomarkers in Adult Smokers","phase":"NA","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Titin Andri Wihastuti","has_results":false},{"nct_id":"NCT03744559","title":"Behavioral Memory Modulation in Nicotine Addiction","phase":"NA","overall_status":"COMPLETED","enrollment_count":191,"lead_sponsor_name":"Medical University of South Carolina","has_results":true},{"nct_id":"NCT06798324","title":"tDCS Plus Varenicline for Smoking Cessation","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":160,"lead_sponsor_name":"Centre for Addiction and Mental Health","has_results":false},{"nct_id":"NCT03694327","title":"Innovative Digital Therapeutic for Smoking Cessation","phase":"NA","overall_status":"COMPLETED","enrollment_count":158,"lead_sponsor_name":"My Digital Study","has_results":true},{"nct_id":"NCT05864586","title":"Developing E-liquid Product Standards (Sweet Spot Study)","phase":"NA","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Ohio State University Comprehensive Cancer Center","has_results":true},{"nct_id":"NCT03635333","title":"Effects of E-Cigarette Flavors on Adults TCORS 2.0","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":130,"lead_sponsor_name":"Yale University","has_results":true},{"nct_id":"NCT01037153","title":"Effects of Nicotine on Brain Activity as Measured by fMRI","phase":"","overall_status":"COMPLETED","enrollment_count":128,"lead_sponsor_name":"National Institute on Drug Abuse (NIDA)","has_results":false},{"nct_id":"NCT04461288","title":"Engaging Sexual and Gender Minority Cigarette Smokers Into Social Media-based Treatment","phase":"NA","overall_status":"COMPLETED","enrollment_count":121,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT07210268","title":"Temporal Interference Methods for Addiction Treatment","phase":"NA","overall_status":"RECRUITING","enrollment_count":120,"lead_sponsor_name":"Indiana University","has_results":false},{"nct_id":"NCT03338933","title":"Neurobiology of Alcohol and Nicotine Co-Addiction","phase":"","overall_status":"COMPLETED","enrollment_count":109,"lead_sponsor_name":"VA Office of Research and Development","has_results":true},{"nct_id":"NCT06688539","title":"E-cigarette Cessation in Adults Who Co-use Cannabis","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":105,"lead_sponsor_name":"Medical University of South Carolina","has_results":false},{"nct_id":"NCT03463837","title":"Identify Biomarkers of Tobacco Exposure and Nicotine Uptake From JUUL 5% in Adult Smokers","phase":"NA","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Juul Labs, Inc.","has_results":false},{"nct_id":"NCT03438188","title":"Neural Basis of Eating Behavior in Abstinent Smokers","phase":"NA","overall_status":"COMPLETED","enrollment_count":82,"lead_sponsor_name":"University of Pennsylvania","has_results":true},{"nct_id":"NCT04772014","title":"Evaluation of the Addictive Potential of E-Cigarettes","phase":"","overall_status":"COMPLETED","enrollment_count":81,"lead_sponsor_name":"Central Institute of Mental Health, Mannheim","has_results":false},{"nct_id":"NCT04709471","title":"E-cigarette Nicotine Study","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":77,"lead_sponsor_name":"University of Vermont","has_results":false},{"nct_id":"NCT04843969","title":"Investigation of Cigarette Cravings in Smokers","phase":"NA","overall_status":"UNKNOWN","enrollment_count":76,"lead_sponsor_name":"Marco Leyton","has_results":false},{"nct_id":"NCT06602492","title":"Compensatory Behavior of E-cig Users in Response to Reduced Nicotine E-liquids","phase":"EARLY_PHASE1","overall_status":"COMPLETED","enrollment_count":72,"lead_sponsor_name":"Rochester Institute of Technology","has_results":false},{"nct_id":"NCT03719391","title":"United States Pre-Market Tobacco Application Pharmacokinetics","phase":"NA","overall_status":"COMPLETED","enrollment_count":67,"lead_sponsor_name":"Juul Labs, Inc.","has_results":false},{"nct_id":"NCT05432830","title":"Sex Differences in E-cig Perception: Study 1","phase":"NA","overall_status":"COMPLETED","enrollment_count":66,"lead_sponsor_name":"Yale University","has_results":false},{"nct_id":"NCT04646174","title":"Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start-II Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":66,"lead_sponsor_name":"Rush University Medical Center","has_results":false},{"nct_id":"NCT05897242","title":"A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults","phase":"NA","overall_status":"COMPLETED","enrollment_count":61,"lead_sponsor_name":"Fred Hutchinson Cancer Center","has_results":true},{"nct_id":"NCT07466875","title":"Auricular Stimulation for Nicotine Withdrawal in Psychiatric Inpatients","phase":"NA","overall_status":"RECRUITING","enrollment_count":60,"lead_sponsor_name":"Chiao-Chiao Liao","has_results":false},{"nct_id":"NCT07398976","title":"Sex Differences in E-Cigarette Perception","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":60,"lead_sponsor_name":"Yale University","has_results":false},{"nct_id":"NCT06544057","title":"Real-time eCounselling for Nicotine Addiction","phase":"NA","overall_status":"RECRUITING","enrollment_count":60,"lead_sponsor_name":"Overcome","has_results":false},{"nct_id":"NCT03264755","title":"Cortical Excitability and Role of rTMS in Nicotine Use Disorder","phase":"NA","overall_status":"UNKNOWN","enrollment_count":60,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT03302026","title":"Real Time fMRI and Quitting Smoking","phase":"NA","overall_status":"COMPLETED","enrollment_count":46,"lead_sponsor_name":"University of Pennsylvania","has_results":false},{"nct_id":"NCT07328594","title":"Impact of Daridorexant on Sleep, Daytime Alertness, and Smoking","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":44,"lead_sponsor_name":"Legacy Health System","has_results":false},{"nct_id":"NCT01369966","title":"Brain Circuits in Schizophrenia and Smoking","phase":"","overall_status":"COMPLETED","enrollment_count":42,"lead_sponsor_name":"National Institute on Drug Abuse (NIDA)","has_results":false},{"nct_id":"NCT03634839","title":"Effects of E-cigarette Flavors on Youth TCORS 2.0","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":42,"lead_sponsor_name":"Yale University","has_results":true},{"nct_id":"NCT06695884","title":"Identify the Optimal TMS Pulse Protocol to Modulate Reward Activity","phase":"NA","overall_status":"RECRUITING","enrollment_count":42,"lead_sponsor_name":"Rutgers, The State University of New Jersey","has_results":false},{"nct_id":"NCT04568395","title":"Acute Effects of TCIG vs ECIG in PLWH","phase":"NA","overall_status":"COMPLETED","enrollment_count":37,"lead_sponsor_name":"University of California, Los Angeles","has_results":false},{"nct_id":"NCT05257109","title":"Water Content in E-Liquids","phase":"NA","overall_status":"COMPLETED","enrollment_count":31,"lead_sponsor_name":"Yale University","has_results":true},{"nct_id":"NCT04250727","title":"Switching to Potential Reduced Exposure Products in Adult Smokers","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Yale University","has_results":true},{"nct_id":"NCT04284813","title":"Families With Substance Use and Psychosis: A Pilot Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":29,"lead_sponsor_name":"Mclean Hospital","has_results":true},{"nct_id":"NCT03700112","title":"Clinical Study Comparing 7 ENDS Products and 1 Combustible Cigarette Using 2 Delivery Methods.","phase":"NA","overall_status":"COMPLETED","enrollment_count":25,"lead_sponsor_name":"Juul Labs, Inc.","has_results":false},{"nct_id":"NCT03593239","title":"Comparing the Pharmacokinetics of Nicotine Salt Based ENDS in Healthy Smokers","phase":"NA","overall_status":"COMPLETED","enrollment_count":24,"lead_sponsor_name":"Juul Labs, Inc.","has_results":false},{"nct_id":"NCT04043728","title":"Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":18,"lead_sponsor_name":"Rush University Medical Center","has_results":true},{"nct_id":"NCT07190352","title":"Behavioral Impact and Neural Correlates of Network-based Brain Stimulation in Schizophrenia","phase":"NA","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"Vanderbilt University Medical Center","has_results":false},{"nct_id":"NCT03213418","title":"Electroretinogram: a New Human Biomarker for Smoking Cessation Treatment","phase":"NA","overall_status":"TERMINATED","enrollment_count":11,"lead_sponsor_name":"New York State Psychiatric Institute","has_results":false},{"nct_id":"NCT04432064","title":"Temporal Interference Neurostimulation and Addiction","phase":"NA","overall_status":"TERMINATED","enrollment_count":10,"lead_sponsor_name":"Indiana University","has_results":true}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}