{"disease":{"id":"muscle-weakness","name":"muscle weakness","therapeutic_area":"","data":{},"enrichment_level":0,"last_enriched_at":null,"visit_count":0,"created_at":"2026-04-19T18:31:21.150Z","updated_at":"2026-04-19T18:39:44.960Z","meddra_pt":null,"meddra_code":null,"icd10_codes":null,"synonyms":[],"prevalence_global":null,"prevalence_us":null,"marketed_drug_count":1,"pipeline_drug_count":0,"trial_count":1},"drugs":{"marketed":[{"drug_id":"aspartame","indication_name":"muscle weakness","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Addiclenz","generic_name":"ASPARTAME","company_name":"Deseret Biologicals, Inc.","drug_phase":"marketed","molecular_target":"","drug_class":"Standardized Chemical Allergen [EPC]","quality_score":16,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03506204","title":"The Pelvic Floor Muscle Function in Chinese Primipara, a One-year Cohort Study","phase":"","overall_status":"UNKNOWN","enrollment_count":3120,"lead_sponsor_name":"Peking Union Medical College Hospital","has_results":false},{"nct_id":"NCT06140862","title":"Ankle Spine Syndrome \"RAFFET Syndrome II","phase":"NA","overall_status":"UNKNOWN","enrollment_count":1000,"lead_sponsor_name":"Noha Khaled Shoukry","has_results":false},{"nct_id":"NCT05318768","title":"Association Between Physical Activity Level ，Overall Muscle Strength and Pelvic Floor Muscle Function in Women.","phase":"","overall_status":"COMPLETED","enrollment_count":929,"lead_sponsor_name":"Peking University People's Hospital","has_results":false},{"nct_id":"NCT03660969","title":"Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":797,"lead_sponsor_name":"University Hospital, Basel, Switzerland","has_results":false},{"nct_id":"NCT03287258","title":"Perineal Preparation for Pregnant Ladies.","phase":"NA","overall_status":"COMPLETED","enrollment_count":400,"lead_sponsor_name":"Kasr El Aini Hospital","has_results":false},{"nct_id":"NCT05639231","title":"An INtervention TO Improve MOBility of Older Hospitalized Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":383,"lead_sponsor_name":"Insel Gruppe AG, University Hospital Bern","has_results":false},{"nct_id":"NCT06216015","title":"Exercise Training and Kidney Transplantation","phase":"NA","overall_status":"COMPLETED","enrollment_count":345,"lead_sponsor_name":"Hugo de Luca Correa","has_results":false},{"nct_id":"NCT05078983","title":"Investigation of Relation With Preoperative Fragility and ASA Score in Elderly Patients","phase":"","overall_status":"UNKNOWN","enrollment_count":320,"lead_sponsor_name":"Gulhane Training and Research Hospital","has_results":false},{"nct_id":"NCT04980586","title":"Cheeks Appearance as a Novel Predictor of Obstructive Sleep Apnea The CASA Score Study","phase":"","overall_status":"COMPLETED","enrollment_count":319,"lead_sponsor_name":"Hospital de Clinicas de Porto Alegre","has_results":false},{"nct_id":"NCT02185989","title":"Electrical Muscle Stimulation and Bicycling Combined to Early Standard Rehabilitation in the ICU","phase":"NA","overall_status":"COMPLETED","enrollment_count":314,"lead_sponsor_name":"Centre Hospitalier Régional d'Orléans","has_results":false},{"nct_id":"NCT03115840","title":"Measuring Outcomes of Activity in Intensive Care","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":312,"lead_sponsor_name":"Vanderbilt University Medical Center","has_results":false},{"nct_id":"NCT04621721","title":"Home-Based Physical Activity Intervention for Taxane-Induced CIPN","phase":"NA","overall_status":"UNKNOWN","enrollment_count":312,"lead_sponsor_name":"University of South Florida","has_results":false},{"nct_id":"NCT05218239","title":"Effect of PEFLOW on PFM Function Recovery of Postpartum Women","phase":"NA","overall_status":"UNKNOWN","enrollment_count":260,"lead_sponsor_name":"Peking University People's Hospital","has_results":false},{"nct_id":"NCT03676478","title":"Assessing Timing of Enteral Feeding Support in Esophageal Cancer Patients on Muscle functTion and Survival","phase":"NA","overall_status":"TERMINATED","enrollment_count":239,"lead_sponsor_name":"University Hospital, Gasthuisberg","has_results":false},{"nct_id":"NCT03452488","title":"A Double-blind, Placebo-controlled, Randomized INTerventional Clinical Trial (SARA-INT)","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":233,"lead_sponsor_name":"Biophytis","has_results":true},{"nct_id":"NCT03021798","title":"An OBServational Clinical Trial (SARA-OBS) in Sarcopenia and Sarcopenic Obesity in Patients Aged 65 Years and Over","phase":"","overall_status":"COMPLETED","enrollment_count":218,"lead_sponsor_name":"Biophytis","has_results":false},{"nct_id":"NCT04715932","title":"Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN)","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":216,"lead_sponsor_name":"Montreal Heart Institute","has_results":true},{"nct_id":"NCT03297632","title":"Improving Muscle Strength, Mass and Physical Function in Older Adults","phase":"NA","overall_status":"UNKNOWN","enrollment_count":210,"lead_sponsor_name":"Region Västerbotten","has_results":false},{"nct_id":"NCT05537298","title":"Muscle Recovery After Critical Illness","phase":"","overall_status":"RECRUITING","enrollment_count":209,"lead_sponsor_name":"Kirby Mayer","has_results":false},{"nct_id":"NCT03543826","title":"Best Practice Using Rocuronium and Reversal With Neostigmine or Sugammadex","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":201,"lead_sponsor_name":"University of Washington","has_results":true},{"nct_id":"NCT07145606","title":"Effects of Early Rehabilitation Using Blood Flow Restriction and/or Surface Electromyography Biofeedback on Quadriceps Activation and Strength After Anterior Cruciate Ligament Reconstruction: A Multicenter Randomized Controlled Trial","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":200,"lead_sponsor_name":"Haute Ecole ARC Sante","has_results":false},{"nct_id":"NCT07436936","title":"OPTIPROT, Targeted Precision Nutrition for Protein Needs in Ageing","phase":"","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Fundació Eurecat","has_results":false},{"nct_id":"NCT03347656","title":"Effects of Mobility Dose on Discharge Disposition in Critically Ill Stroke Patients","phase":"","overall_status":"COMPLETED","enrollment_count":164,"lead_sponsor_name":"Beth Israel Deaconess Medical Center","has_results":false},{"nct_id":"NCT03301116","title":"Promoting Seniors' Health With Home Care Aides","phase":"NA","overall_status":"COMPLETED","enrollment_count":157,"lead_sponsor_name":"University of Illinois at Chicago","has_results":false},{"nct_id":"NCT05897970","title":"Association Between 4-Month Isokinetic Testing Measures and Second Knee Injuries After Primary Anterior Cruciate Ligament Reconstruction","phase":"","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"University Hospital, Caen","has_results":false},{"nct_id":"NCT05719922","title":"The ADAPTation to Therapeutic Resistance Training (ADAPT) Study","phase":"NA","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"Defence Medical Rehabilitation Centre, UK","has_results":false},{"nct_id":"NCT06850155","title":"Gluteal Sling Release on Gluteal Dysfunction After in Primary Total Hip Arthroplasty","phase":"NA","overall_status":"COMPLETED","enrollment_count":144,"lead_sponsor_name":"Ankara City Hospital Bilkent","has_results":false},{"nct_id":"NCT07420569","title":"Multimodal Pelvic Floor Rehabilitation in Chronic Stroke Survivors: Long-Term Efficacy, Optimal Protocols, and Adjunctive Therapies for Comprehensive Pelvic Floor Dysfunction.","phase":"NA","overall_status":"COMPLETED","enrollment_count":140,"lead_sponsor_name":"Iqra National University","has_results":false},{"nct_id":"NCT07425314","title":"Effects of The Telerehabilitation-Based Exercise Program in Liver Transplant Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":140,"lead_sponsor_name":"Hasan Kalyoncu University","has_results":false},{"nct_id":"NCT04343599","title":"Hypopressive Effectiveness in Postural Control and Pelvic Floor.","phase":"NA","overall_status":"COMPLETED","enrollment_count":130,"lead_sponsor_name":"University of Jaén","has_results":false},{"nct_id":"NCT05263596","title":"SARCOPEDIA - Sarcopenia Diagnostics in Aging Medicine","phase":"NA","overall_status":"RECRUITING","enrollment_count":120,"lead_sponsor_name":"University Department of Geriatric Medicine FELIX PLATTER","has_results":false},{"nct_id":"NCT05465291","title":"Neuromuscular Electrical Stimulation in Mechanically Ventilated Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"Damanhour University","has_results":false},{"nct_id":"NCT03581760","title":"Cycling Exercise in Mechanical Ventilation","phase":"NA","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"University Hospital Ostrava","has_results":false},{"nct_id":"NCT06977919","title":"NASM OPT for Pectoral Enhancement and Breast Firmness in Non-Athletic Women: An RCT","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":120,"lead_sponsor_name":"University of Sistan and Baluchestan","has_results":false},{"nct_id":"NCT03788577","title":"Impact of Oligonol to Cardiometabolic Risk and Muscular Health","phase":"NA","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"National Yang Ming Chiao Tung University","has_results":false},{"nct_id":"NCT04382378","title":"Effects of NMES in Critically Ill Patients","phase":"NA","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"Escola Superior de Ciencias da Saude","has_results":false},{"nct_id":"NCT06977958","title":"NASM OPT for Gluteal Enhancement in Non-Athletic Women: An RCT","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":120,"lead_sponsor_name":"University of Sistan and Baluchestan","has_results":false},{"nct_id":"NCT06122441","title":"RE-inventing Strategies for Healthy Ageing; Recommendations and Tools","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":119,"lead_sponsor_name":"University of Tromso","has_results":false},{"nct_id":"NCT04862481","title":"Physical Function of Older Citizens During Municipality-based Rehabilitation","phase":"","overall_status":"COMPLETED","enrollment_count":115,"lead_sponsor_name":"University College Absalon","has_results":false},{"nct_id":"NCT04333186","title":"Expiratory Muscle Function in Critically Ill Ventilated Patients","phase":"","overall_status":"COMPLETED","enrollment_count":113,"lead_sponsor_name":"Amsterdam UMC, location VUmc","has_results":false},{"nct_id":"NCT04071912","title":"Isokinetic Muscular Assessment After ACL Ligamentoplasty: Study of Factors Predictive of Muscle Imbalance.","phase":"","overall_status":"COMPLETED","enrollment_count":113,"lead_sponsor_name":"University Hospital, Caen","has_results":false},{"nct_id":"NCT05389566","title":"Diabetes, Falls, and Fractures","phase":"","overall_status":"COMPLETED","enrollment_count":110,"lead_sponsor_name":"Aalborg University Hospital","has_results":false},{"nct_id":"NCT04956705","title":"Vitamin D and Calcium Supplementation at Danish Nursing Homes","phase":"NA","overall_status":"COMPLETED","enrollment_count":109,"lead_sponsor_name":"University College Copenhagen","has_results":false},{"nct_id":"NCT03252132","title":"Resistance Training in Patients With Diabetic Neuropathy","phase":"NA","overall_status":"COMPLETED","enrollment_count":109,"lead_sponsor_name":"Danish Pain Research Center","has_results":false},{"nct_id":"NCT04368325","title":"Low Creatinine Level and Respiratory Failure","phase":"","overall_status":"COMPLETED","enrollment_count":107,"lead_sponsor_name":"Osijek University Hospital","has_results":false},{"nct_id":"NCT03473873","title":"Protective Role of Muscle Function for Early Features of Knee Osteoarthritis After Anterior Cruciate Ligament Injury","phase":"","overall_status":"COMPLETED","enrollment_count":106,"lead_sponsor_name":"Lund University","has_results":false},{"nct_id":"NCT05288712","title":"Effectiveness of a Training Protocol With the Cervical Device in Subjects With Deep Cervical Muscle Strength Deficit.","phase":"NA","overall_status":"COMPLETED","enrollment_count":105,"lead_sponsor_name":"Universitat Internacional de Catalunya","has_results":false},{"nct_id":"NCT05712109","title":"Changes in the Force-velocity Relationship of Knee Muscles After ACL Reconstruction","phase":"","overall_status":"COMPLETED","enrollment_count":103,"lead_sponsor_name":"University Hospital, Caen","has_results":false},{"nct_id":"NCT03586440","title":"Effect of Forward Head and Rounded Shoulder Posture on Hand Grip Strength in Asymptomatic Young Adults","phase":"","overall_status":"COMPLETED","enrollment_count":102,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT03991702","title":"Hand Grip Strength and Medical Research Council Scale as Predictors of Weaning Failure","phase":"","overall_status":"COMPLETED","enrollment_count":102,"lead_sponsor_name":"Hospital de Clinicas de Porto Alegre","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}