{"disease":{"id":"mild-dementia","name":"mild dementia"},"drugs":{"marketed":[{"drug_id":"galantamine","indication_name":"Mild to moderate dementia of the Alzheimer's type","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Razadyne","generic_name":"GALANTAMINE","company_name":"Johnson & Johnson","drug_phase":"marketed","molecular_target":"Acetylcholinesterase","drug_class":"Cholinesterase Inhibitor","quality_score":62,"revenue":null,"mechanism":"Razadyne works by blocking the enzyme that breaks down acetylcholine, allowing more of this neurotransmitter to be available in the brain."},{"drug_id":"galantamine-hydrobromide","indication_name":"Mild to moderate dementia of the Alzheimer's type","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"GALANTAMINE HYDROBROMIDE","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":31,"revenue":null,"mechanism":null},{"drug_id":"benzgalantamine","indication_name":"mild to moderate dementia of the Alzheimer's type","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Zunveyl","generic_name":"BENZGALANTAMINE","company_name":"Alpha Cognition","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":56,"revenue":null,"mechanism":"Zunveyl works by enhancing communication between brain cells, specifically by stimulating cholinergic receptors."}],"pipeline":[],"offLabel":[],"totalMarketed":3,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06090578","title":"TabCAT Brain Health Assessment in Primary Care","phase":"NA","overall_status":"RECRUITING","enrollment_count":180000,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT03653156","title":"China Cognition and Aging Study","phase":"","overall_status":"RECRUITING","enrollment_count":100000,"lead_sponsor_name":"Capital Medical University","has_results":false},{"nct_id":"NCT04701177","title":"Digitally-enhanced, Decentralized, Multi-omics Observational Cohort","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":100000,"lead_sponsor_name":"Greece 2021 Committee","has_results":false},{"nct_id":"NCT05922319","title":"Effects of Training Dose on Computerized Cognitive Training in Patients With Cognitive Impairment","phase":"","overall_status":"COMPLETED","enrollment_count":21845,"lead_sponsor_name":"Xuanwu Hospital, Beijing","has_results":false},{"nct_id":"NCT04262206","title":"Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":20000,"lead_sponsor_name":"Duke University","has_results":false},{"nct_id":"NCT06650969","title":"China Diabetes Cognitive Dysfunction Early Diagnosis and Intervention Study (China-DECODE Study)","phase":"","overall_status":"RECRUITING","enrollment_count":10000,"lead_sponsor_name":"The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School","has_results":false},{"nct_id":"NCT03672448","title":"The China Longitudinal Aging Study of Cognitive Impairment","phase":"","overall_status":"UNKNOWN","enrollment_count":10000,"lead_sponsor_name":"Shanghai Mental Health Center","has_results":false},{"nct_id":"NCT04114994","title":"Longitudinal Cognitive Assessment by BoCA","phase":"","overall_status":"RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Alzheimer's Light LLC","has_results":false},{"nct_id":"NCT04680013","title":"Genetic Studies in Familial Dementia","phase":"","overall_status":"COMPLETED","enrollment_count":4884,"lead_sponsor_name":"University of Miami","has_results":false},{"nct_id":"NCT06889818","title":"Korean Joint Registry for Alzheimer's Treatment and Diagnostics (JOY-ALZ)","phase":"","overall_status":"RECRUITING","enrollment_count":4000,"lead_sponsor_name":"Ewha Womans University Mokdong Hospital","has_results":false},{"nct_id":"NCT07016178","title":"Innovative Cognitive Impairment Case Finding and Engagement for Diverse Participation in Alzheimer's Disease Care, Treatment, And Research","phase":"NA","overall_status":"COMPLETED","enrollment_count":3454,"lead_sponsor_name":"Indiana University","has_results":false},{"nct_id":"NCT07238049","title":"REAl World Dementia OUTcomes: Observational Study","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":3165,"lead_sponsor_name":"University of Oxford","has_results":false},{"nct_id":"NCT07347574","title":"NeuroCare Community Project: A Community Based Prospective Observational Study for Early Alzheimer's Detection in HK","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":2500,"lead_sponsor_name":"Hong Kong University of Science and Technology","has_results":false},{"nct_id":"NCT03657745","title":"Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Alzheimer's Light LLC","has_results":false},{"nct_id":"NCT03233646","title":"Retinal Imaging in Neurodegenerative Disease","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Duke University","has_results":false},{"nct_id":"NCT05617014","title":"Alzheimer's Disease Neuroimaging Initiative 4","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":1500,"lead_sponsor_name":"University of Southern California","has_results":false},{"nct_id":"NCT04171323","title":"The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia","phase":"NA","overall_status":"RECRUITING","enrollment_count":1305,"lead_sponsor_name":"University of Alabama at Birmingham","has_results":false},{"nct_id":"NCT06122415","title":"The Swedish BioFINDER - Memory Clinic Study","phase":"","overall_status":"RECRUITING","enrollment_count":1200,"lead_sponsor_name":"Skane University Hospital","has_results":false},{"nct_id":"NCT03325699","title":"Support Monitoring and Reminder Technology","phase":"NA","overall_status":"UNKNOWN","enrollment_count":1200,"lead_sponsor_name":"Johan Sanmartin Berglund","has_results":false},{"nct_id":"NCT06120361","title":"The Swedish BioFINDER - Primary Care Study","phase":"","overall_status":"RECRUITING","enrollment_count":1200,"lead_sponsor_name":"Skane University Hospital","has_results":false},{"nct_id":"NCT07504965","title":"Dementia-friendly Apothecaries as a Resource for Mental Heath in the Elderly","phase":"","overall_status":"RECRUITING","enrollment_count":1020,"lead_sponsor_name":"Ludwig-Maximilians - University of Munich","has_results":false},{"nct_id":"NCT05372172","title":"Tennessee Alzheimer's Project","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Vanderbilt University Medical Center","has_results":false},{"nct_id":"NCT06121544","title":"The Swedish BioFINDER - Preclinical AD Study","phase":"","overall_status":"RECRUITING","enrollment_count":800,"lead_sponsor_name":"Skane University Hospital","has_results":false},{"nct_id":"NCT07364019","title":"The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":700,"lead_sponsor_name":"University of British Columbia","has_results":false},{"nct_id":"NCT05532657","title":"ACHIEVE Brain Health Follow-Up Study","phase":"PHASE3","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":629,"lead_sponsor_name":"Johns Hopkins University","has_results":false},{"nct_id":"NCT06809725","title":"Software Validation Study-Cognitive Status Indicator","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":600,"lead_sponsor_name":"Spark Neuro Inc.","has_results":false},{"nct_id":"NCT07214974","title":"Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.","phase":"EARLY_PHASE1","overall_status":"NOT_YET_RECRUITING","enrollment_count":600,"lead_sponsor_name":"Noah Tech, Corp.","has_results":false},{"nct_id":"NCT02843529","title":"Evaluation of a Computerized Complex Instrumental Activities of Daily Living Marker (NMI)","phase":"NA","overall_status":"COMPLETED","enrollment_count":548,"lead_sponsor_name":"Altoida","has_results":true},{"nct_id":"NCT07041450","title":"Screening for Anti-amyloid Treatment Eligibility Using Digital Cognition and Blood-based Biomarkers","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"MoCA Clinic and Institute","has_results":false},{"nct_id":"NCT03275363","title":"The University of Hong Kong Neurocognitive Disorder Cohort","phase":"","overall_status":"UNKNOWN","enrollment_count":500,"lead_sponsor_name":"The University of Hong Kong","has_results":false},{"nct_id":"NCT06703541","title":"ADRC Clinical Cohort (Alzheimer's Disease)","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Duke University","has_results":false},{"nct_id":"NCT06993207","title":"HOme-based Brain Monitoring With a GARment-EEG to Study Cognitive Decline in the Aging Population","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Bitbrain","has_results":false},{"nct_id":"NCT05107882","title":"Optina Diagnostics' Cerebral ß-Amyloid Status (CAS) Test","phase":"","overall_status":"COMPLETED","enrollment_count":466,"lead_sponsor_name":"Optina Diagnostics Inc.","has_results":false},{"nct_id":"NCT03682185","title":"The Healthy Patterns Sleep Study","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":421,"lead_sponsor_name":"University of Pennsylvania","has_results":true},{"nct_id":"NCT05399888","title":"A Study to Learn About the Safety of BIIB080 Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age","phase":"PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":416,"lead_sponsor_name":"Biogen","has_results":false},{"nct_id":"NCT03653234","title":"TV-based Service to Support People Living With Mild Dementia or Mild Cognitive Impariment","phase":"NA","overall_status":"COMPLETED","enrollment_count":404,"lead_sponsor_name":"Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud","has_results":false},{"nct_id":"NCT06025877","title":"Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey","phase":"","overall_status":"UNKNOWN","enrollment_count":400,"lead_sponsor_name":"C2N Diagnostics","has_results":false},{"nct_id":"NCT05477056","title":"Quality Improvement PrecivityAD Clinician Survey (QUIP I)","phase":"","overall_status":"COMPLETED","enrollment_count":366,"lead_sponsor_name":"C2N Diagnostics","has_results":false},{"nct_id":"NCT05175664","title":"Novel Diagnostic and Disease Stage Biomarkers in AD","phase":"","overall_status":"COMPLETED","enrollment_count":350,"lead_sponsor_name":"Danish Dementia Research Centre","has_results":false},{"nct_id":"NCT05427448","title":"Validation of Blood Biomarkers for Alzheimer's Disease","phase":"NA","overall_status":"COMPLETED","enrollment_count":342,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT03550131","title":"Innovations in Dementia Empowerment and Action","phase":"NA","overall_status":"COMPLETED","enrollment_count":322,"lead_sponsor_name":"University of Washington","has_results":true},{"nct_id":"NCT03466177","title":"Multimodal Retinal Imaging in the Detection and Follow-up of Alzheimer's Disease","phase":"","overall_status":"UNKNOWN","enrollment_count":320,"lead_sponsor_name":"Universitaire Ziekenhuizen KU Leuven","has_results":false},{"nct_id":"NCT07422857","title":"Evaluate the Use of [18F]-APN-1607 PET in Subjects With AD-related Cognitive Impairment and Subjects With Normal Cognitive Function","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":316,"lead_sponsor_name":"JYAMS PET Research & Development Limited","has_results":false},{"nct_id":"NCT05380297","title":"Validation of acceXible's Automated Speech Analysis Method for the Early Detection and Monitoring of Patients With Mild Impairment or Dementia in Primary Care","phase":"NA","overall_status":"COMPLETED","enrollment_count":273,"lead_sponsor_name":"Accexible","has_results":false},{"nct_id":"NCT07037550","title":"Effectiveness of Strength-based Intervention for Elderly With Dementia Living in the Community","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":272,"lead_sponsor_name":"The University of Hong Kong","has_results":false},{"nct_id":"NCT05565976","title":"Dapagliflozin Effect in Cognitive Impairment in Stroke Trial","phase":"PHASE2, PHASE3","overall_status":"UNKNOWN","enrollment_count":270,"lead_sponsor_name":"Jaime Daniel Mondragon","has_results":false},{"nct_id":"NCT01081743","title":"Effectiveness of Care Management in Alzheimer Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":270,"lead_sponsor_name":"Institut de Sante Publique, d'Epidemiologie et de Developpement","has_results":false},{"nct_id":"NCT03875326","title":"Stimulation to Improve Memory","phase":"NA","overall_status":"COMPLETED","enrollment_count":269,"lead_sponsor_name":"University of Michigan","has_results":false},{"nct_id":"NCT06347172","title":"Deprescribing in Patients Living With Dementia With Caregiver and Provider Nudges","phase":"NA","overall_status":"COMPLETED","enrollment_count":250,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false},{"nct_id":"NCT06584110","title":"Buddy-Up Dyadic Physical Activity Program for Persons With Dementia and Family Caregivers","phase":"NA","overall_status":"RECRUITING","enrollment_count":236,"lead_sponsor_name":"The University of Hong Kong","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}