{"disease":{"id":"memory","name":"memory"},"drugs":{"marketed":[{"drug_id":"pramiracetam","indication_name":"Memory impairment","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Amacetam","generic_name":"PRAMIRACETAM","company_name":"","drug_phase":"phase_2","molecular_target":"","drug_class":"pramiracetam","quality_score":null,"revenue":null,"mechanism":"Pramiracetam works by increasing the activity of certain neurotransmitters in the brain, such as acetylcholine, to enhance memory and cognitive function."}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04701177","title":"Digitally-enhanced, Decentralized, Multi-omics Observational Cohort","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":100000,"lead_sponsor_name":"Greece 2021 Committee","has_results":false},{"nct_id":"NCT03894254","title":"Predictive Factors of Autonomy Loss in Real-life Cohort","phase":"NA","overall_status":"RECRUITING","enrollment_count":5400,"lead_sponsor_name":"Hospices Civils de Lyon","has_results":false},{"nct_id":"NCT02213458","title":"Care Ecosystem: Navigating Patients and Families Through Stages of Care","phase":"NA","overall_status":"COMPLETED","enrollment_count":1560,"lead_sponsor_name":"University of California, San Francisco","has_results":true},{"nct_id":"NCT05364307","title":"Identification of Patients With a High Probability of Meeting Eligibility Criteria for an Alzheimer's Disease Clinical Trial (APHELEIA)","phase":"","overall_status":"COMPLETED","enrollment_count":1555,"lead_sponsor_name":"Global Alzheimer's Platform Foundation","has_results":false},{"nct_id":"NCT01231971","title":"Alzheimer's Disease Neuroimaging Initiative 2","phase":"","overall_status":"COMPLETED","enrollment_count":1182,"lead_sponsor_name":"University of Southern California","has_results":false},{"nct_id":"NCT04733989","title":"A Biomarker Database to Investigate Blood-Based and Digital Biomarkers in Participants Screened for Alzheimer's Disease (Bio-Hermes)","phase":"","overall_status":"COMPLETED","enrollment_count":1002,"lead_sponsor_name":"GAP Innovations, PBC","has_results":false},{"nct_id":"NCT07429591","title":"Risk Screening & Primary Prevention of Elder Abuse in People Living With Dementia","phase":"NA","overall_status":"SUSPENDED","enrollment_count":1000,"lead_sponsor_name":"University of Southern California","has_results":false},{"nct_id":"NCT04362696","title":"Improving Working Memory in Older Adults","phase":"NA","overall_status":"COMPLETED","enrollment_count":964,"lead_sponsor_name":"Boston University Charles River Campus","has_results":false},{"nct_id":"NCT04287738","title":"Care Ecosystem: Navigating Patients and Families Through Stages of Care, Extension Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":912,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT06427265","title":"Machine Learning-based Longitudinal Study of Post-ICU Syndrome Development Trajectory in Critically Ill Patients and Construction of Clinical Early Warning Models: a Research Protocol for Longitudinal Study","phase":"","overall_status":"RECRUITING","enrollment_count":840,"lead_sponsor_name":"The Affiliated Hospital Of Guizhou Medical University","has_results":false},{"nct_id":"NCT00001480","title":"The Evaluation and Follow-up of Individuals With Memory Disorder","phase":"","overall_status":"COMPLETED","enrollment_count":750,"lead_sponsor_name":"National Institute of Mental Health (NIMH)","has_results":false},{"nct_id":"NCT02843529","title":"Evaluation of a Computerized Complex Instrumental Activities of Daily Living Marker (NMI)","phase":"NA","overall_status":"COMPLETED","enrollment_count":548,"lead_sponsor_name":"Altoida","has_results":true},{"nct_id":"NCT04330677","title":"Dissecting the Role of Estradiol in Mediating Gender-specific Anxiolytic and Prosocial Effects of Oxytocin","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":487,"lead_sponsor_name":"University Hospital, Bonn","has_results":false},{"nct_id":"NCT00029120","title":"Evaluation of Age- and Alzheimer's Disease-Related Memory Disorder","phase":"","overall_status":"COMPLETED","enrollment_count":450,"lead_sponsor_name":"National Institute of Mental Health (NIMH)","has_results":false},{"nct_id":"NCT03682185","title":"The Healthy Patterns Sleep Study","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":421,"lead_sponsor_name":"University of Pennsylvania","has_results":true},{"nct_id":"NCT07218120","title":"In-Person Recruitment of Individuals to the Alzheimer's Prevention Trial (APT) Webstudy","phase":"NA","overall_status":"RECRUITING","enrollment_count":400,"lead_sponsor_name":"University of Southern California","has_results":false},{"nct_id":"NCT06821178","title":"My Life and My Experiences Project","phase":"NA","overall_status":"RECRUITING","enrollment_count":400,"lead_sponsor_name":"University of California, Irvine","has_results":false},{"nct_id":"NCT06025877","title":"Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey","phase":"","overall_status":"UNKNOWN","enrollment_count":400,"lead_sponsor_name":"C2N Diagnostics","has_results":false},{"nct_id":"NCT05611918","title":"REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":350,"lead_sponsor_name":"Johns Hopkins University","has_results":false},{"nct_id":"NCT05550727","title":"The PorchLight Project","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":342,"lead_sponsor_name":"University of Minnesota","has_results":false},{"nct_id":"NCT05952284","title":"Couples Health Aging, Rhythms and Sleep Study","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":340,"lead_sponsor_name":"University of Utah","has_results":false},{"nct_id":"NCT04783740","title":"Validity and Reliability of Turkish Version of The Working Memory Questionnaire","phase":"","overall_status":"COMPLETED","enrollment_count":303,"lead_sponsor_name":"Kutahya Health Sciences University","has_results":false},{"nct_id":"NCT02814526","title":"Exercise in Adults With Mild Memory Problems","phase":"NA","overall_status":"COMPLETED","enrollment_count":296,"lead_sponsor_name":"Alzheimer's Disease Cooperative Study (ADCS)","has_results":true},{"nct_id":"NCT05756231","title":"Cultural and Linguistic Adaptation and Normative Study of the Turkish Version of the Free and Cued Selective Reminding Test: 16-Word Version (FCSRT-T)","phase":"NA","overall_status":"COMPLETED","enrollment_count":285,"lead_sponsor_name":"Istanbul University","has_results":false},{"nct_id":"NCT03268109","title":"COGnitive ImpairmenT in Older HIV-infected Patients ≥ 65 Years Old","phase":"","overall_status":"COMPLETED","enrollment_count":281,"lead_sponsor_name":"Fondation Ophtalmologique Adolphe de Rothschild","has_results":false},{"nct_id":"NCT02822573","title":"Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":276,"lead_sponsor_name":"Wake Forest University Health Sciences","has_results":true},{"nct_id":"NCT03144921","title":"EPIC: An Intervention for Early-stage AD Dyads - Adapted for Virtual Delivery","phase":"NA","overall_status":"COMPLETED","enrollment_count":272,"lead_sponsor_name":"Arizona State University","has_results":false},{"nct_id":"NCT03723850","title":"Effect of Noninvasive Electrical Brain Stimulation on Memory at Different Times of Day in Younger and Older Adults","phase":"NA","overall_status":"COMPLETED","enrollment_count":271,"lead_sponsor_name":"University of Chicago","has_results":true},{"nct_id":"NCT05027789","title":"Brain Boosters 2 in Persons at Risk for Alzheimer's Disease: a Digital Application Supported Intervention","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":263,"lead_sponsor_name":"University of California, Davis","has_results":false},{"nct_id":"NCT03723694","title":"Dietary Modulation of Neuroinflammation in Age-Related Memory Disorders","phase":"NA","overall_status":"COMPLETED","enrollment_count":259,"lead_sponsor_name":"Columbia University","has_results":false},{"nct_id":"NCT02525198","title":"The Cognitive Ageing Nutrition and Neurogenesis (CANN) Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":259,"lead_sponsor_name":"University of East Anglia","has_results":false},{"nct_id":"NCT07402161","title":"The Signature of Alzheimer's Disease in Subjective Cognitive Decline","phase":"","overall_status":"RECRUITING","enrollment_count":250,"lead_sponsor_name":"IRCCS Policlinico S. Donato","has_results":false},{"nct_id":"NCT05806697","title":"Investigation of AlzHeimer's Predictors in Subjective Memory Complainers - Extension Study","phase":"NA","overall_status":"RECRUITING","enrollment_count":240,"lead_sponsor_name":"Institut National de la Santé Et de la Recherche Médicale, France","has_results":false},{"nct_id":"NCT07251985","title":"Cognitive Effects of Bioavailable Curcumin","phase":"PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":240,"lead_sponsor_name":"University of California, Los Angeles","has_results":false},{"nct_id":"NCT07461584","title":"Memory Enhancement in Aging With Optimal Dosing","phase":"EARLY_PHASE1","overall_status":"NOT_YET_RECRUITING","enrollment_count":240,"lead_sponsor_name":"Boston University Charles River Campus","has_results":false},{"nct_id":"NCT05877196","title":"A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses","phase":"NA","overall_status":"RECRUITING","enrollment_count":216,"lead_sponsor_name":"Arizona State University","has_results":false},{"nct_id":"NCT03949868","title":"Mindful Attention to Variability in Everyday Memory","phase":"NA","overall_status":"UNKNOWN","enrollment_count":210,"lead_sponsor_name":"Harvard University","has_results":false},{"nct_id":"NCT05625425","title":"Wayfinding Intervention and Long-Term Memory","phase":"NA","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT05122598","title":"Development and Evaluation of Computerized Olfactory Training Program for Cognitive Decline in Early Alzheimer's Disease","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Evon Medics LLC","has_results":false},{"nct_id":"NCT07294586","title":"Exploratory Clinical Study and Validation of Blood Biomarkers for Alzheimer's Disease","phase":"","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Amoneta Diagnostics SAS","has_results":false},{"nct_id":"NCT05645770","title":"Prospective Memory and Cardiac Activity in Coronary Artery Disease","phase":"","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"National Taiwan University Hospital","has_results":false},{"nct_id":"NCT04480112","title":"Impact of Covid-19 on Frequent Social Interaction Through Communication Technologies in the Cognitive Status of Socially-isolated Older Adults","phase":"NA","overall_status":"COMPLETED","enrollment_count":196,"lead_sponsor_name":"Boston University","has_results":false},{"nct_id":"NCT05746299","title":"The Impact of Reactivation During Sleep on the Consolidation of Abstract Information in Humans","phase":"NA","overall_status":"COMPLETED","enrollment_count":194,"lead_sponsor_name":"University of Pennsylvania","has_results":true},{"nct_id":"NCT03982147","title":"White Matter Connections and Memory: the STRATEGIC Study","phase":"","overall_status":"UNKNOWN","enrollment_count":193,"lead_sponsor_name":"King's College London","has_results":false},{"nct_id":"NCT05929898","title":"MRI Neurofeedback and Brain Circuits Related to Motivation in Healthy Participants","phase":"NA","overall_status":"RECRUITING","enrollment_count":190,"lead_sponsor_name":"Duke University","has_results":false},{"nct_id":"NCT03490149","title":"Prediction of the Cognitive Effects of Electroconvulsive Therapy Via Machine Learning and Neuroimaging","phase":"","overall_status":"UNKNOWN","enrollment_count":180,"lead_sponsor_name":"University Hospital, Bonn","has_results":false},{"nct_id":"NCT05986604","title":"NIA_Improving Function and Well-being by Improving Patient Memory: Transdiagnostic Sleep and Circadian Treatment","phase":"NA","overall_status":"RECRUITING","enrollment_count":178,"lead_sponsor_name":"University of California, Berkeley","has_results":false},{"nct_id":"NCT03537729","title":"Effects of Visual Cues and Education for People Who Live Within Long Term Care Communities to Assist in Wayfinding","phase":"NA","overall_status":"COMPLETED","enrollment_count":172,"lead_sponsor_name":"Grand Valley State University","has_results":true},{"nct_id":"NCT03592251","title":"26 Weeks' Dietary Supplementation With DHA- and EPA-enriched Oils on Memory Consolidation in Healthy Adults","phase":"NA","overall_status":"COMPLETED","enrollment_count":168,"lead_sponsor_name":"Northumbria University","has_results":false},{"nct_id":"NCT02757794","title":"Long-term Effects of Visual Spatial Working Memory Training Program Performed at Preschool Age in Very Preterm Infants With Visual Spatial Working Memory Deficit. A Randomized Controlled Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":166,"lead_sponsor_name":"Assistance Publique Hopitaux De Marseille","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}