{"disease":{"id":"melas-syndrome","name":"melas syndrome"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06013397","title":"Effectiveness of Ketogenic Diet in MELAS Syndrome","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":100,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT03888716","title":"A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":72,"lead_sponsor_name":"Abliva AB","has_results":false},{"nct_id":"NCT04378075","title":"A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy","phase":"PHASE2, PHASE3","overall_status":"TERMINATED","enrollment_count":68,"lead_sponsor_name":"PTC Therapeutics","has_results":true},{"nct_id":"NCT03056209","title":"Safety, Tolerability and Pharmacokinetic Study of KL1333 in Healthy Male Volunteers","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Yungjin Pharm. Co., Ltd.","has_results":false},{"nct_id":"NCT06402123","title":"A Phase 2b Study of Zagociguat in Patients With MELAS","phase":"PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":43,"lead_sponsor_name":"Tisento Therapeutics","has_results":false},{"nct_id":"NCT04165239","title":"The KHENERGYZE Study","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":27,"lead_sponsor_name":"Khondrion BV","has_results":false},{"nct_id":"NCT06644534","title":"A Study to Assess TTI-0102 vs Placebo in MELAS Patients","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":12,"lead_sponsor_name":"Thiogenesis Therapeutics, Inc.","has_results":false},{"nct_id":"NCT03952234","title":"L-Citrulline Dose Finding Safety Study in MELAS","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":10,"lead_sponsor_name":"Baylor College of Medicine","has_results":false},{"nct_id":"NCT04948138","title":"Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":9,"lead_sponsor_name":"Jesús González de la Aleja Tejera","has_results":false},{"nct_id":"NCT05255328","title":"Clinical Long Term Evaluation of Glutamine Supplement in MELAS Syndrome","phase":"NA","overall_status":"UNKNOWN","enrollment_count":9,"lead_sponsor_name":"Hospital Universitario 12 de Octubre","has_results":false}],"total":10},"guidelines":[],"source":"Drug Landscape verified database"}