{"disease":{"id":"marfan-syndrome","name":"marfan syndrome"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04774172","title":"Mortality and Morbidity Outcomes in Marfans","phase":"","overall_status":"COMPLETED","enrollment_count":6700,"lead_sponsor_name":"Barts & The London NHS Trust","has_results":false},{"nct_id":"NCT03440697","title":"Pathogenetic Basis of Aortopathy and Aortic Valve Disease","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":3000,"lead_sponsor_name":"Yale University","has_results":false},{"nct_id":"NCT00270686","title":"Studies of Heritable Disorders of Connective Tissue","phase":"","overall_status":"COMPLETED","enrollment_count":929,"lead_sponsor_name":"National Institute on Aging (NIA)","has_results":false},{"nct_id":"NCT06546137","title":"National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry","phase":"","overall_status":"RECRUITING","enrollment_count":600,"lead_sponsor_name":"Hospital do Coracao","has_results":false},{"nct_id":"NCT04970459","title":"Biological Collection for Marfan and Related Syndromes","phase":"","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"University Hospital, Toulouse","has_results":false},{"nct_id":"NCT05516043","title":"Safety and Performance of POLYTHESE® Vascular Prosthesis","phase":"","overall_status":"COMPLETED","enrollment_count":256,"lead_sponsor_name":"Perouse Medical","has_results":false},{"nct_id":"NCT06257004","title":"Genome-wide Epistasis for Cardiovascular Severity in Marfan Study","phase":"","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"University Hospital, Antwerp","has_results":false},{"nct_id":"NCT07169669","title":"Multicentre Longitudinal Study of Bone Mineralisation Characteristics in Marfan Syndrome and Ehlers-Danlos Syndrome","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":150,"lead_sponsor_name":"IRCCS Policlinico S. Donato","has_results":false},{"nct_id":"NCT05944614","title":"Towards Optimal Treatment of Marfan Syndrome","phase":"","overall_status":"COMPLETED","enrollment_count":148,"lead_sponsor_name":"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","has_results":false},{"nct_id":"NCT05712577","title":"Psychological Support in Adult Patients With Marfan Syndrome","phase":"","overall_status":"UNKNOWN","enrollment_count":125,"lead_sponsor_name":"IRCCS Policlinico S. Donato","has_results":false},{"nct_id":"NCT07419386","title":"Clinical and Psychosocial Factors Associated With Physical Activity Level in Adults With Marfan Syndrome","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":118,"lead_sponsor_name":"University of Oviedo","has_results":false},{"nct_id":"NCT04319107","title":"Classifying Ectopia Lentis in Marfan Syndrome Into Five Grades of Increasing Severity","phase":"","overall_status":"COMPLETED","enrollment_count":110,"lead_sponsor_name":"Hospices Civils de Lyon","has_results":false},{"nct_id":"NCT05711693","title":"Measurement of Heart-carotid Pulse Wave Velocity (hcPWV) by Laser Doppler Vibrometry (LDV)","phase":"NA","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"Institut National de la Santé Et de la Recherche Médicale, France","has_results":false},{"nct_id":"NCT05980104","title":"Single-Session \"Empowered Relief\" Class for Marfan Syndrome and Related Conditions","phase":"NA","overall_status":"COMPLETED","enrollment_count":92,"lead_sponsor_name":"Stanford University","has_results":false},{"nct_id":"NCT05123339","title":"Clinical Signs and Activity Limitations Associated With Dural Ectasia in Patients With Marfan Disease","phase":"","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT04776668","title":"Living With Marfan Syndrome and Your Aorta","phase":"","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Barts & The London NHS Trust","has_results":false},{"nct_id":"NCT04553094","title":"Effects of Personalized Training at Home Combining Endurance and Resistance in Patients Suffering From Marfan Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":72,"lead_sponsor_name":"French Cardiology Society","has_results":false},{"nct_id":"NCT04731493","title":"Effect on the Quality of Life of a Therapeutic Education Program in Patients With Marfan Syndrome","phase":"","overall_status":"UNKNOWN","enrollment_count":60,"lead_sponsor_name":"University Hospital, Toulouse","has_results":false},{"nct_id":"NCT05578469","title":"Surgical Treatment of Marfan Syndrome With Subluxation Lens","phase":"","overall_status":"UNKNOWN","enrollment_count":50,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT05809323","title":"Marfan Syndrome Moderate Exercise Trial II","phase":"NA","overall_status":"RECRUITING","enrollment_count":50,"lead_sponsor_name":"Baylor College of Medicine","has_results":false},{"nct_id":"NCT07360704","title":"Genotypes and Craniofacial Phenotypes in Orthodontic Patients With Marfan and Loeys-Dietz Syndromes","phase":"","overall_status":"COMPLETED","enrollment_count":39,"lead_sponsor_name":"Andrea Scribante","has_results":false},{"nct_id":"NCT03236571","title":"Cardiorespiratory and Muscular Rehabilitation of Children and Young Adults With Marfan Syndrome.","phase":"NA","overall_status":"COMPLETED","enrollment_count":28,"lead_sponsor_name":"University Hospital, Toulouse","has_results":false},{"nct_id":"NCT04776681","title":"Living With Marfans and Your Aorta: Surgical Outcomes Study","phase":"","overall_status":"COMPLETED","enrollment_count":28,"lead_sponsor_name":"Barts & The London NHS Trust","has_results":false},{"nct_id":"NCT03567460","title":"Children and Adolescents With Marfan Syndrome: 10,000 Healthy Steps and Beyond","phase":"NA","overall_status":"COMPLETED","enrollment_count":24,"lead_sponsor_name":"Stanford University","has_results":false},{"nct_id":"NCT04641325","title":"Marfan Syndrome Moderate Exercise Pilot","phase":"NA","overall_status":"COMPLETED","enrollment_count":23,"lead_sponsor_name":"Baylor College of Medicine","has_results":false},{"nct_id":"NCT00782327","title":"Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic Root Dilatation in Patients With Marfan Syndrome Under Treatment With Beta-blockers","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":22,"lead_sponsor_name":"University Hospital, Ghent","has_results":false},{"nct_id":"NCT02213484","title":"Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes","phase":"","overall_status":"COMPLETED","enrollment_count":20,"lead_sponsor_name":"University of Colorado, Denver","has_results":false},{"nct_id":"NCT03581682","title":"Tele-Clinic Visits in Pediatric Marfan Patients Using Parental Echo: The Future?","phase":"NA","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"Stanford University","has_results":false},{"nct_id":"NCT07495267","title":"Nutritional Ketosis Marfan","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":15,"lead_sponsor_name":"Washington University School of Medicine","has_results":false},{"nct_id":"NCT06872268","title":"APPLICATION OF THERAPEUTIC PHOTOGRAPHY AND EXPRESSIVE WRITING IN THE MANAGEMENT OF PATIENTS WITH MARFAN SYNDROME","phase":"NA","overall_status":"COMPLETED","enrollment_count":8,"lead_sponsor_name":"IRCCS Policlinico S. Donato","has_results":false}],"total":30},"guidelines":[],"source":"Drug Landscape verified database"}