{"disease":{"id":"malignant-brain-tumor","name":"malignant brain tumor"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04351035","title":"National Wide Cross-sectional Study in Paediatric Central Nervous System Tumours in China -- the CNOG-MC001 Registry","phase":"","overall_status":"COMPLETED","enrollment_count":4303,"lead_sponsor_name":"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","has_results":false},{"nct_id":"NCT06092125","title":"Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease","phase":"","overall_status":"RECRUITING","enrollment_count":2300,"lead_sponsor_name":"Xuanwu Hospital, Beijing","has_results":false},{"nct_id":"NCT03222258","title":"Prospective Cohort Study Depending on the Use of Palliative Care for Advanced Stage of Cancer Patients","phase":"","overall_status":"COMPLETED","enrollment_count":444,"lead_sponsor_name":"Seoul National University Hospital","has_results":false},{"nct_id":"NCT06098248","title":"Evaluation of cCeLL-Ex Vivo Confocal Microscopy for Real-time Brain Tumor Diagnosis","phase":"NA","overall_status":"TERMINATED","enrollment_count":285,"lead_sponsor_name":"VPIX Medical","has_results":true},{"nct_id":"NCT05622409","title":"A Taiwanese Oncogenetic Panel and Integrated Clinical Data Registry Study for Diffuse Glioma","phase":"","overall_status":"RECRUITING","enrollment_count":250,"lead_sponsor_name":"National Health Research Institutes, Taiwan","has_results":false},{"nct_id":"NCT02058745","title":"SmartCare: Innovations in Caregiving Interventions","phase":"NA","overall_status":"COMPLETED","enrollment_count":240,"lead_sponsor_name":"University of Pittsburgh","has_results":false},{"nct_id":"NCT06273176","title":"The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma","phase":"","overall_status":"RECRUITING","enrollment_count":225,"lead_sponsor_name":"Erasmus Medical Center","has_results":false},{"nct_id":"NCT06810544","title":"Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":191,"lead_sponsor_name":"Tango Therapeutics, Inc.","has_results":false},{"nct_id":"NCT07158710","title":"Phase I Study of HSK42360 in Malignant Brain Tumors With BRAF V600 Mutation","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":159,"lead_sponsor_name":"Haisco Pharmaceutical Group Co., Ltd.","has_results":false},{"nct_id":"NCT06788886","title":"Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases","phase":"NA","overall_status":"RECRUITING","enrollment_count":147,"lead_sponsor_name":"Mayo Clinic","has_results":false},{"nct_id":"NCT05538130","title":"A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":124,"lead_sponsor_name":"Pfizer","has_results":false},{"nct_id":"NCT04109209","title":"Psychological Intervention For Brain Tumor Caregivers","phase":"NA","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"Massachusetts General Hospital","has_results":false},{"nct_id":"NCT06989086","title":"FearLess in NeuroOncology","phase":"NA","overall_status":"RECRUITING","enrollment_count":112,"lead_sponsor_name":"Virginia Commonwealth University","has_results":false},{"nct_id":"NCT06099743","title":"ASCENT Intervention for Brain Tumor Patients","phase":"NA","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"Massachusetts General Hospital","has_results":false},{"nct_id":"NCT03423992","title":"Personalized Chimeric Antigen Receptor T Cell Immunotherapy for Patients With Recurrent Malignant Gliomas","phase":"PHASE1","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Xuanwu Hospital, Beijing","has_results":false},{"nct_id":"NCT05850377","title":"5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":90,"lead_sponsor_name":"Sociedad de Lucha Contra el Cáncer del Ecuador","has_results":false},{"nct_id":"NCT02303678","title":"D2C7 for Adult Patients With Recurrent Malignant Glioma","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":81,"lead_sponsor_name":"Darell Bigner","has_results":false},{"nct_id":"NCT03434262","title":"SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":68,"lead_sponsor_name":"St. Jude Children's Research Hospital","has_results":false},{"nct_id":"NCT05857969","title":"Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":65,"lead_sponsor_name":"Florida International University","has_results":false},{"nct_id":"NCT05976490","title":"NeuroPathways Intervention for Brain Tumor Patients","phase":"NA","overall_status":"RECRUITING","enrollment_count":50,"lead_sponsor_name":"Massachusetts General Hospital","has_results":false},{"nct_id":"NCT02798406","title":"Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":49,"lead_sponsor_name":"DNAtrix, Inc.","has_results":false},{"nct_id":"NCT04171895","title":"Communication Training for Caregivers In Advanced Care Planning","phase":"","overall_status":"COMPLETED","enrollment_count":49,"lead_sponsor_name":"Memorial Sloan Kettering Cancer Center","has_results":false},{"nct_id":"NCT01505569","title":"Auto Transplant for High Risk or Relapsed Solid or CNS Tumors","phase":"NA","overall_status":"COMPLETED","enrollment_count":44,"lead_sponsor_name":"Masonic Cancer Center, University of Minnesota","has_results":false},{"nct_id":"NCT03684109","title":"Non-invasive Glioma Characterization Through Molecular Imaging","phase":"NA","overall_status":"RECRUITING","enrollment_count":30,"lead_sponsor_name":"University of Miami","has_results":false},{"nct_id":"NCT07118176","title":"Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":30,"lead_sponsor_name":"Jonsson Comprehensive Cancer Center","has_results":false},{"nct_id":"NCT04897880","title":"A Study of Panobinostat in Pediatric Patients With Solid Tumors Including MRT/ATRT","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":25,"lead_sponsor_name":"Australian & New Zealand Children's Haematology/Oncology Group","has_results":false},{"nct_id":"NCT04668508","title":"Anlotinib to Malignant Brainstem Glioma","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":25,"lead_sponsor_name":"Zhejiang Cancer Hospital","has_results":false},{"nct_id":"NCT03860376","title":"Ex Vivo Drug Sensitivity Testing and Mutation Profiling","phase":"","overall_status":"COMPLETED","enrollment_count":25,"lead_sponsor_name":"Florida International University","has_results":false},{"nct_id":"NCT01705548","title":"Hypofractionated Stereotactic Radiosurgery in Treating Patients With Large Brain Metastasis","phase":"NA","overall_status":"COMPLETED","enrollment_count":25,"lead_sponsor_name":"Emory University","has_results":false},{"nct_id":"NCT03911388","title":"HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":24,"lead_sponsor_name":"M.D. Anderson Cancer Center","has_results":false},{"nct_id":"NCT04396717","title":"Safety Study of Pritumumab in Brain Cancer","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"Nascent Biotech","has_results":false},{"nct_id":"NCT05892653","title":"A Study of ABM-1310 in Patients With BRAF V600-Mutant Relapsed and Drug Resistant Primary Malignant Brain Tumors","phase":"PHASE1","overall_status":"TERMINATED","enrollment_count":15,"lead_sponsor_name":"ABM Therapeutics Shanghai Company Limited","has_results":false},{"nct_id":"NCT02967380","title":"Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases","phase":"NA","overall_status":"TERMINATED","enrollment_count":14,"lead_sponsor_name":"University of Southern California","has_results":false},{"nct_id":"NCT05169944","title":"Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":13,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT07438860","title":"Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG","phase":"PHASE1","overall_status":"NOT_YET_RECRUITING","enrollment_count":12,"lead_sponsor_name":"Tiffany Hodges","has_results":false},{"nct_id":"NCT05798273","title":"(68^Ga)-GaPSMA-11 PET/MR-imaging of Malignant Intra-axial Brain Tumors","phase":"NA","overall_status":"COMPLETED","enrollment_count":12,"lead_sponsor_name":"Erasmus Medical Center","has_results":false},{"nct_id":"NCT03615404","title":"Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":11,"lead_sponsor_name":"Gary Archer Ph.D.","has_results":true},{"nct_id":"NCT02338037","title":"Neuropharmacokinetics of Eribulin Mesylate in Treating Patients With Primary or Metastatic Brain Tumors","phase":"EARLY_PHASE1","overall_status":"COMPLETED","enrollment_count":8,"lead_sponsor_name":"City of Hope Medical Center","has_results":false},{"nct_id":"NCT03043391","title":"Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":8,"lead_sponsor_name":"Istari Oncology, Inc.","has_results":true},{"nct_id":"NCT02885324","title":"Pilot Study of Cabozantinib for Recurrent or Progressive Central Nervous System Tumors in Children","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":4,"lead_sponsor_name":"Indiana University","has_results":true},{"nct_id":"NCT05669326","title":"Evaluation of the Contribution of NODDI Protocol Tractography in Brain Tumor Surgery","phase":"NA","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"GCS Ramsay Santé pour l'Enseignement et la Recherche","has_results":false},{"nct_id":"NCT04069910","title":"Stereotactic Radiation Therapy Before Surgery for the Treatment of Resectable Brain Metastases","phase":"NA","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"Jonsson Comprehensive Cancer Center","has_results":false},{"nct_id":"NCT04521946","title":"Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer","phase":"PHASE1","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"M.D. Anderson Cancer Center","has_results":false}],"total":43},"guidelines":[],"source":"Drug Landscape verified database"}