{"disease":{"id":"liver-metastasis","name":"liver metastasis"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06179602","title":"Prospective Cohort Study on Thermal Ablation of Malignant Liver Tumors","phase":"","overall_status":"RECRUITING","enrollment_count":1500,"lead_sponsor_name":"Leiden University Medical Center","has_results":false},{"nct_id":"NCT07180641","title":"National Registry of Hepatic Metastases From Non-Colorectal Cancer\"","phase":"","overall_status":"COMPLETED","enrollment_count":1039,"lead_sponsor_name":"Clinica Universidad de Navarra, Universidad de Navarra","has_results":false},{"nct_id":"NCT07385521","title":"The Use of Artificial Intelligence for the Prediction of Recurrence After Resection of Colorectal Liver Metastases","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Francesco De Cobelli","has_results":false},{"nct_id":"NCT04622423","title":"Advanced Therapies for Liver Metastases","phase":"","overall_status":"RECRUITING","enrollment_count":625,"lead_sponsor_name":"IRCCS San Raffaele","has_results":false},{"nct_id":"NCT06111105","title":"GUIDE.MRD-01-CRC: Clinical Validation and Benchmarking of Top Performing CtDNA Diagnostics - Colorectal Cancer","phase":"","overall_status":"RECRUITING","enrollment_count":590,"lead_sponsor_name":"Claus Lindbjerg Andersen","has_results":false},{"nct_id":"NCT04686942","title":"Sonazoid-enhanced Ultrasound for the Detection of Colorectal Liver Metastases Less Than 2 cm","phase":"","overall_status":"UNKNOWN","enrollment_count":550,"lead_sponsor_name":"Sun Yat-sen University","has_results":false},{"nct_id":"NCT07272928","title":"Comparison of the Resection Site Order in Simultaneous Approach of Colorectal Liver Metastasis","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria","has_results":false},{"nct_id":"NCT03981497","title":"Microwave Ablation for Treatment of Small Renal Tumors and Primary and Secondary Liver Neoplasms","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Francesco De Cobelli","has_results":false},{"nct_id":"NCT04172753","title":"Feasibility of Online MR-guided Radiotherapy on a 1.5T MR-Linac","phase":"NA","overall_status":"RECRUITING","enrollment_count":472,"lead_sponsor_name":"University Hospital Tuebingen","has_results":false},{"nct_id":"NCT06936098","title":"Deep Learning-Based Analysis of Colorectal Cancer Pathology Images: An Innovative Approach for Predicting Colorectal Cancer Subtypes","phase":"","overall_status":"COMPLETED","enrollment_count":431,"lead_sponsor_name":"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","has_results":false},{"nct_id":"NCT03428477","title":"EPA for Metastasis Trial 2","phase":"PHASE3","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":418,"lead_sponsor_name":"Mark A Hull, PhD FRCP","has_results":false},{"nct_id":"NCT05861505","title":"COLLISION RELAPSE Trial","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":360,"lead_sponsor_name":"Amsterdam UMC, location VUmc","has_results":false},{"nct_id":"NCT02453490","title":"Compare Efficacy and Safety of Raltitrexed-based and 5fu-based Neoadjuvant Chemotherapy for Colorectal Liver Metastasis","phase":"PHASE3","overall_status":"TERMINATED","enrollment_count":360,"lead_sponsor_name":"Zhejiang University","has_results":false},{"nct_id":"NCT04163887","title":"Effect of the Laparoscopic Approach in Reducing Postoperative Severe Complications Following Hepatectomy for Colorectal Liver Metastases","phase":"NA","overall_status":"UNKNOWN","enrollment_count":340,"lead_sponsor_name":"Institut Mutualiste Montsouris","has_results":false},{"nct_id":"NCT06988852","title":"FOLFOX-HAIC as Conversion Treatment for Initially Unresectable Colorectal Liver Metastasis","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Tongji Hospital","has_results":false},{"nct_id":"NCT06550700","title":"The Outcomes of Laparoscopic Hybrid Surgery Versus Totally Open Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":266,"lead_sponsor_name":"Changhai Hospital","has_results":false},{"nct_id":"NCT04634526","title":"Prospective Clinical Study of Intraoperative Assessment of Resection Margin of Colo-Rectal Cancer Liver Metastases","phase":"","overall_status":"UNKNOWN","enrollment_count":250,"lead_sponsor_name":"Oncology Institute of Vojvodina","has_results":false},{"nct_id":"NCT05293041","title":"Argipressin's Influence on Blood Loss During Hepatic Resection","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":248,"lead_sponsor_name":"Kristina Svennerholm","has_results":false},{"nct_id":"NCT03895723","title":"Minimally Invasive Versus Open Liver Resection for Patients With Colorectal Cancer Liver Metastases","phase":"NA","overall_status":"UNKNOWN","enrollment_count":220,"lead_sponsor_name":"Xu jianmin","has_results":false},{"nct_id":"NCT04798898","title":"Improving Survival of COlorectal LIver Metastases by RFA-mediated Immunostimulation","phase":"NA","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"University of Aarhus","has_results":false},{"nct_id":"NCT03127072","title":"Study Comparing Radio Frequency Ablation Plus Chemotherapy and Chemotherapy Alone in Patients With Unresectable CRLM","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Fudan University","has_results":false},{"nct_id":"NCT04597710","title":"Precision Medicine for Liver Tumours With Quantitative Magnetic Resonance Imaging and Whole Genome Sequencing","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":200,"lead_sponsor_name":"Perspectum","has_results":false},{"nct_id":"NCT05314400","title":"Gadoxetate Abbreviated MRI in Metastatic Colorectal Cancer","phase":"NA","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","has_results":false},{"nct_id":"NCT07027605","title":"Multi-Reader Multi-Case Trial Evaluating Computer-Aided Tool for Prognostic Prediction of Colorectal Liver Metastases","phase":"","overall_status":"RECRUITING","enrollment_count":166,"lead_sponsor_name":"Cancer Institute and Hospital, Chinese Academy of Medical Sciences","has_results":false},{"nct_id":"NCT04417010","title":"To Identify KRAS Gene and Safe Margin in Association With Outcome in Colorectal Liver Metastases Following Ultrasound-guided Radiofrequency Ablation","phase":"","overall_status":"UNKNOWN","enrollment_count":163,"lead_sponsor_name":"Peking University Cancer Hospital & Institute","has_results":false},{"nct_id":"NCT04832776","title":"FOLFOXIRI Plus Cetuximab Versus FOLFOXIRI Plus Bevacizumab in Conversion Therapy of Right-sided Colon Cancer Liver Metastases","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":160,"lead_sponsor_name":"Fudan University","has_results":false},{"nct_id":"NCT02642978","title":"Robot-assisted Procedure Versus Open Simultaneous Resection of Colorectal Cancer With Liver Metastases","phase":"NA","overall_status":"UNKNOWN","enrollment_count":160,"lead_sponsor_name":"Xu jianmin","has_results":false},{"nct_id":"NCT07392567","title":"Prospective Validation of an AI Model for Predicting Liver Metastasis in Colorectal Cancer","phase":"","overall_status":"RECRUITING","enrollment_count":160,"lead_sponsor_name":"Tongji Hospital","has_results":false},{"nct_id":"NCT06671418","title":"Primary Percutaneous Stenting Above the Ampulla Versus Endoscopic Drainage for Unresectable Malignant Hilar Biliary Obstruction","phase":"PHASE3","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":148,"lead_sponsor_name":"Erasmus Medical Center","has_results":false},{"nct_id":"NCT03589339","title":"NBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 Therapy","phase":"PHASE1","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":145,"lead_sponsor_name":"Nanobiotix","has_results":false},{"nct_id":"NCT02456285","title":"Colorectal Cancer With Liver-limited Synchronous Metastases: an Inception Cohort Study of Standardised Care Pathways","phase":"","overall_status":"COMPLETED","enrollment_count":123,"lead_sponsor_name":"Manchester University NHS Foundation Trust","has_results":false},{"nct_id":"NCT04755907","title":"3D Bioprinted Models for Predicting Chemotherapy Response in Colorectal Cancer With/Without Liver Metastases","phase":"","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"Peking Union Medical College Hospital","has_results":false},{"nct_id":"NCT06630624","title":"Dose Finding, Efficacy and Immunological Response of IP-001 Following MWA or IRE for CRLM","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":120,"lead_sponsor_name":"M.R. Meijerink","has_results":false},{"nct_id":"NCT07159048","title":"The Safety, Efficacy, and Immune Response of Multimodal Thermal Therapy in the Treatment of Malignant Liver Tumors","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":120,"lead_sponsor_name":"Fudan University","has_results":false},{"nct_id":"NCT07381309","title":"Oncolytic Virus (H101) + SBRT + Chemotherapy + Targeted Therapy + Immunotherapy for Unresectable CRLM","phase":"PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":114,"lead_sponsor_name":"Jun Huang","has_results":false},{"nct_id":"NCT06018142","title":"Clinical Application of Super-resolution Ultrasound(SR-US) Imaging in Solid Tumors","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Chinese PLA General Hospital","has_results":false},{"nct_id":"NCT07173868","title":"FDG PET-CT in Advanced Breast Cancer","phase":"","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"Samsung Medical Center","has_results":false},{"nct_id":"NCT04046445","title":"Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer","phase":"PHASE1","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":96,"lead_sponsor_name":"Amal Therapeutics","has_results":false},{"nct_id":"NCT06980792","title":"Surgical Approach for Adenocarcinoma of the Pancreas With Synchronous Liver Metastases","phase":"","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Azienda Ospedaliero-Universitaria di Modena","has_results":false},{"nct_id":"NCT05362825","title":"Surgery Outcome Treated by Neo-adjuvant Combination of Oxaliplatin, Irinotecan, Folinic Acid and Fluorouracil (FOLFOXIRI) Regimen in Synchronous Liver Limited Metastasis Colorectal Cancer","phase":"","overall_status":"UNKNOWN","enrollment_count":89,"lead_sponsor_name":"Cho Ray Hospital","has_results":false},{"nct_id":"NCT05718349","title":"FGF19 in Obstructive Cholestasis: \"Unveil the Signal\"","phase":"","overall_status":"UNKNOWN","enrollment_count":81,"lead_sponsor_name":"Nicole Hildebrand","has_results":false},{"nct_id":"NCT04682665","title":"Prebiotic Effect of Eicosapentaenoic Acid Treatment for Colorectal Cancer Liver Metastases","phase":"","overall_status":"COMPLETED","enrollment_count":81,"lead_sponsor_name":"University of Leeds","has_results":false},{"nct_id":"NCT06200831","title":"Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases","phase":"NA","overall_status":"RECRUITING","enrollment_count":80,"lead_sponsor_name":"Oslo University Hospital","has_results":false},{"nct_id":"NCT04668872","title":"Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation","phase":"","overall_status":"RECRUITING","enrollment_count":80,"lead_sponsor_name":"Memorial Sloan Kettering Cancer Center","has_results":false},{"nct_id":"NCT06185556","title":"COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases","phase":"PHASE2, PHASE3","overall_status":"RECRUITING","enrollment_count":78,"lead_sponsor_name":"Amsterdam UMC, location VUmc","has_results":false},{"nct_id":"NCT06021015","title":"Safety and Efficacy of Polyvinyl Alcohol Sodium Acrylate Embolization Microspheres for CRLM","phase":"NA","overall_status":"UNKNOWN","enrollment_count":72,"lead_sponsor_name":"Zhongda Hospital","has_results":false},{"nct_id":"NCT04081168","title":"COLLISION XL: Unresectable Colorectal Liver Metastases (3-5cm): Stereotactic Body Radiotherapy vs. Microwave Ablation","phase":"NA","overall_status":"UNKNOWN","enrollment_count":68,"lead_sponsor_name":"Amsterdam UMC, location VUmc","has_results":false},{"nct_id":"NCT03841305","title":"Simultaneous Portal and Hepatic Vein Versus Portal Vein Embolizations for Hypertrophy of the Future Liver Remnant","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":64,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT06356584","title":"Fruquintinib Combined With Sintilimab ± Radiotherapy for Third-line Treatment of Colorectal Cancer With Liver Metastases","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":62,"lead_sponsor_name":"Shandong Cancer Hospital and Institute","has_results":false},{"nct_id":"NCT05495529","title":"Biliary or Digestive Protection by Room Air Interposition for Thermal Ablation of Central Hepatic Tumors","phase":"","overall_status":"COMPLETED","enrollment_count":61,"lead_sponsor_name":"Centre Hospitalier Universitaire de Nice","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}