{"disease":{"id":"lewy-body-disease","name":"lewy body disease"},"drugs":{"marketed":[{"drug_id":"zonegran","indication_name":"Diffuse Lewy body disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"Zonegran","company_name":"Dr. Reddy's Laboratories Limited","drug_phase":"marketed","molecular_target":"Amine oxidase [flavin-containing] B, Carbonic anhydrase 1, Carbonic anhydrase 12","drug_class":"","quality_score":null,"revenue":null,"mechanism":null}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06209515","title":"Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register Study","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":61292,"lead_sponsor_name":"Kuopio University Hospital","has_results":false},{"nct_id":"NCT06203106","title":"NYSCF Scientific Discovery Biobank","phase":"","overall_status":"RECRUITING","enrollment_count":10000,"lead_sponsor_name":"New York Stem Cell Foundation Research Institute","has_results":false},{"nct_id":"NCT03233646","title":"Retinal Imaging in Neurodegenerative Disease","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Duke University","has_results":false},{"nct_id":"NCT06949865","title":"AI-Enhanced Optimization of Acute Levodopa Challenge Test","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT02213458","title":"Care Ecosystem: Navigating Patients and Families Through Stages of Care","phase":"NA","overall_status":"COMPLETED","enrollment_count":1560,"lead_sponsor_name":"University of California, San Francisco","has_results":true},{"nct_id":"NCT06120361","title":"The Swedish BioFINDER - Primary Care Study","phase":"","overall_status":"RECRUITING","enrollment_count":1200,"lead_sponsor_name":"Skane University Hospital","has_results":false},{"nct_id":"NCT06122415","title":"The Swedish BioFINDER - Memory Clinic Study","phase":"","overall_status":"RECRUITING","enrollment_count":1200,"lead_sponsor_name":"Skane University Hospital","has_results":false},{"nct_id":"NCT04715399","title":"UPenn Observational Research Repository on Neurodegenerative Disease","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"University of Pennsylvania","has_results":false},{"nct_id":"NCT04287738","title":"Care Ecosystem: Navigating Patients and Families Through Stages of Care, Extension Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":912,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT03076671","title":"More Than a Movement Disorder: Applying Palliative Care to Parkinson's Disease","phase":"NA","overall_status":"COMPLETED","enrollment_count":783,"lead_sponsor_name":"University of Colorado, Denver","has_results":false},{"nct_id":"NCT06389032","title":"PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":622,"lead_sponsor_name":"Rush University Medical Center","has_results":false},{"nct_id":"NCT06596746","title":"Neurodegenerative Diseases Progression Markers (MARKERS-NDD)","phase":"","overall_status":"RECRUITING","enrollment_count":600,"lead_sponsor_name":"Casa di Cura San Raffaele Cassino","has_results":false},{"nct_id":"NCT02448784","title":"Post-marketing Surveillance of Donepezil Hydrochloride - Investigation of Long Term Safety and Efficacy of Aricept as Well as Its Proper Use Information in Patients With Dementia With Lewy Bodies (DLB).","phase":"","overall_status":"COMPLETED","enrollment_count":591,"lead_sponsor_name":"Eisai Co., Ltd.","has_results":false},{"nct_id":"NCT03623672","title":"North American Prodromal Synucleinopathy Consortium","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":500,"lead_sponsor_name":"Washington University School of Medicine","has_results":false},{"nct_id":"NCT05916664","title":"Efficacy Study of Kinto Care Coaching for Dementia Family Caregivers","phase":"NA","overall_status":"COMPLETED","enrollment_count":495,"lead_sponsor_name":"Kinto","has_results":true},{"nct_id":"NCT04428112","title":"Rural Dementia Caregiver Project","phase":"NA","overall_status":"COMPLETED","enrollment_count":418,"lead_sponsor_name":"University of California, San Francisco","has_results":true},{"nct_id":"NCT06217237","title":"Optimization and Harmonization of Advanced MRI Sequences","phase":"","overall_status":"COMPLETED","enrollment_count":400,"lead_sponsor_name":"IRCCS Centro Neurolesi Bonino Pulejo","has_results":false},{"nct_id":"NCT05779839","title":"A Study of Caregiver Connections Via Technology in Dementia","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":355,"lead_sponsor_name":"Mayo Clinic","has_results":false},{"nct_id":"NCT04997642","title":"Parkinson's Disease and Movement Disorders Clinical Database","phase":"","overall_status":"RECRUITING","enrollment_count":250,"lead_sponsor_name":"University of Pennsylvania","has_results":false},{"nct_id":"NCT06005935","title":"Environmental and Reproductive Health Risk for Lewy Body Dementia","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":225,"lead_sponsor_name":"University of California, San Diego","has_results":false},{"nct_id":"NCT03508024","title":"Patients With Alzheimer's Disease or Related Youth Disease","phase":"","overall_status":"COMPLETED","enrollment_count":220,"lead_sponsor_name":"University Hospital, Lille","has_results":false},{"nct_id":"NCT05019014","title":"Olfactory Deficits in Neurologic Disease","phase":"","overall_status":"COMPLETED","enrollment_count":201,"lead_sponsor_name":"Massachusetts General Hospital","has_results":false},{"nct_id":"NCT05444244","title":"A Relational Research Recruitment and Engagement Intervention for Cognitive Aging Research","phase":"NA","overall_status":"COMPLETED","enrollment_count":182,"lead_sponsor_name":"University of Wisconsin, Madison","has_results":true},{"nct_id":"NCT06826157","title":"The Role of Advanced Electroencephalographic Data as Marker of Pathology and Prognosis in Primary Dementias","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":175,"lead_sponsor_name":"IRCCS San Raffaele","has_results":false},{"nct_id":"NCT02345213","title":"A Post-Marketing Clinical Study of Aricept in Patients With Dementia With Lewy Bodies (DLB)","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":160,"lead_sponsor_name":"Eisai Co., Ltd.","has_results":false},{"nct_id":"NCT05014971","title":"Telehealth in Lewy Body Dementia","phase":"NA","overall_status":"RECRUITING","enrollment_count":106,"lead_sponsor_name":"University of Florida","has_results":false},{"nct_id":"NCT03724136","title":"Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":100,"lead_sponsor_name":"MD Stem Cells","has_results":false},{"nct_id":"NCT05518409","title":"Immunohistochemical Study of Neurodegenerative Diseases","phase":"NA","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"First Affiliated Hospital of Zhejiang University","has_results":false},{"nct_id":"NCT06745011","title":"Prodromal Model of Parkinson's Disease Confined to The Peripheral Nervous System","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":100,"lead_sponsor_name":"University of Aarhus","has_results":false},{"nct_id":"NCT04148391","title":"NYX-458 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's Disease or Lewy Body Dementia (Cognition, Memory, Attention, Thinking)","phase":"PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":99,"lead_sponsor_name":"Aptinyx","has_results":false},{"nct_id":"NCT05847985","title":"Language and Lewy Body Diseases: Sentence Comprehension Problems and Modifying Noninvasive Brain Stimulation Treatment","phase":"NA","overall_status":"RECRUITING","enrollment_count":90,"lead_sponsor_name":"Masaryk University","has_results":false},{"nct_id":"NCT04649164","title":"Learning to PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia","phase":"NA","overall_status":"COMPLETED","enrollment_count":87,"lead_sponsor_name":"Rush University Medical Center","has_results":true},{"nct_id":"NCT04165213","title":"Care of Persons With Dementia in Their Environments (COPE) in Programs of All-Inclusive Care of the Elderly (PACE)","phase":"NA","overall_status":"COMPLETED","enrollment_count":85,"lead_sponsor_name":"University of Pennsylvania","has_results":true},{"nct_id":"NCT03472482","title":"Optical Coherence Tomography in Cerebral Amyloidosis","phase":"","overall_status":"UNKNOWN","enrollment_count":85,"lead_sponsor_name":"Universitaire Ziekenhuizen KU Leuven","has_results":false},{"nct_id":"NCT06978946","title":"Deep Cervical Lymphaticovenous Anastomosis Surgery for Moderate-to-Advanced Dementia Patients","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":85,"lead_sponsor_name":"RenJi Hospital","has_results":false},{"nct_id":"NCT02871427","title":"Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":80,"lead_sponsor_name":"Axovant Sciences Ltd.","has_results":false},{"nct_id":"NCT06221202","title":"Stories in the Moment: Dance Program for People Living With Dementia","phase":"NA","overall_status":"UNKNOWN","enrollment_count":72,"lead_sponsor_name":"DanceStream Projects","has_results":false},{"nct_id":"NCT07240805","title":"Digital Health Technologies for Progressive Supranuclear Palsy and Dementia With Lewy Bodies","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":60,"lead_sponsor_name":"BioSensics","has_results":false},{"nct_id":"NCT04963855","title":"A Phase I Study of GT300 in Healthy Subjects","phase":"PHASE1","overall_status":"UNKNOWN","enrollment_count":56,"lead_sponsor_name":"Generian Pharmaceuticals, Inc.","has_results":false},{"nct_id":"NCT04794634","title":"Relationship Between Alzheimer Disease and Diminution of the Three Macular Nervous Retinal Layers","phase":"NA","overall_status":"COMPLETED","enrollment_count":55,"lead_sponsor_name":"Centre Hospitalier Universitaire, Amiens","has_results":false},{"nct_id":"NCT04436341","title":"Epileptic Activity in Patients With Alzheimer's Disease and Lewy Body Dementia","phase":"","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"Danish Dementia Research Centre","has_results":false},{"nct_id":"NCT05508646","title":"Group-Based Telehealth Music Therapy Intervention for Patients With Dementia: A Pilot Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":48,"lead_sponsor_name":"Geisinger Clinic","has_results":false},{"nct_id":"NCT04739423","title":"A Study of Clenbuterol (CST-103) Co-administered With Nadolol (CST-107) in Subjects With Neurodegenerative Disorders","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":41,"lead_sponsor_name":"CuraSen Therapeutics, Inc.","has_results":true},{"nct_id":"NCT06733714","title":"Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults","phase":"NA","overall_status":"RECRUITING","enrollment_count":40,"lead_sponsor_name":"Universidade Federal do Rio de Janeiro","has_results":false},{"nct_id":"NCT05622734","title":"VOCALE LBD+ for Caregivers of Persons With Lewy Body Dementia","phase":"NA","overall_status":"COMPLETED","enrollment_count":39,"lead_sponsor_name":"University of Washington","has_results":true},{"nct_id":"NCT04764669","title":"A Study of E2027 in Participants With Dementia With Lewy Bodies (DLB) or Parkinson's Disease Dementia (PDD) With or Without Amyloid Copathology","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":34,"lead_sponsor_name":"Eisai Inc.","has_results":true},{"nct_id":"NCT06263673","title":"Anti-Diabetic Medications to Fight PD and LBD","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":18,"lead_sponsor_name":"Mayo Clinic","has_results":true},{"nct_id":"NCT05778695","title":"Brain Small Chain Fatty Acid Metabolism in Parkinson Disease: Ketones","phase":"NA","overall_status":"TERMINATED","enrollment_count":16,"lead_sponsor_name":"University of Michigan","has_results":true},{"nct_id":"NCT04817891","title":"Stimulation of Cingulo-opercular Alertness Network","phase":"NA","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"University of Michigan","has_results":true},{"nct_id":"NCT05188105","title":"Alpha tACS in Dementia With Lewy Bodies","phase":"NA","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}