{"disease":{"id":"intracranial-hemorrhage","name":"intracranial hemorrhage"},"drugs":{"marketed":[{"drug_id":"nimodipine","indication_name":"Subarachnoid intracranial hemorrhage","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Nimotop","generic_name":"NIMODIPINE","company_name":"","drug_phase":"marketed","molecular_target":"Voltage-dependent L-type calcium channel subunit alpha-1F","drug_class":"Dihydropyridine Calcium Channel Blocker [EPC]","quality_score":50,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06456814","title":"Epidemiological Insights Into the Formation, Progression, and Rupture of Intracranial Aneurysms: A Retrospective, Multi-Center Hospital-Based Study in China","phase":"","overall_status":"RECRUITING","enrollment_count":30000,"lead_sponsor_name":"Zhujiang Hospital","has_results":false},{"nct_id":"NCT04242784","title":"IMPROVE Stroke Care- Developing and Optimizing Regional Systems of Stroke Care","phase":"","overall_status":"COMPLETED","enrollment_count":21646,"lead_sponsor_name":"Duke University","has_results":false},{"nct_id":"NCT03209258","title":"The Third, Intensive Care Bundle With Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":7067,"lead_sponsor_name":"The George Institute for Global Health, China","has_results":false},{"nct_id":"NCT07175519","title":"Safety and Efficacy of Aneurysms Treated With Endovascular Devices","phase":"","overall_status":"RECRUITING","enrollment_count":5000,"lead_sponsor_name":"King's College London","has_results":false},{"nct_id":"NCT05364749","title":"Selective CT for Anticoagulated Head Injured Patients","phase":"","overall_status":"RECRUITING","enrollment_count":4000,"lead_sponsor_name":"Dr. Kerstin de Wit","has_results":false},{"nct_id":"NCT05609721","title":"Mild Traumatic Brain Injury and the Risk for Traumatic Intracranial Hemorrhage","phase":"","overall_status":"COMPLETED","enrollment_count":2044,"lead_sponsor_name":"Umeå University","has_results":false},{"nct_id":"NCT06320132","title":"BLANDISH (Brain, Loss of Function, Aneurism, Disease, Injury, Stroke, Hemorrhage)","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"IRCCS Ospedale San Raffaele","has_results":false},{"nct_id":"NCT05609110","title":"Safety and Efficacy of Remote Ischemic Conditioning for Spontaneous Intracerebral Hemorrhage","phase":"NA","overall_status":"UNKNOWN","enrollment_count":2000,"lead_sponsor_name":"Yi Yang","has_results":false},{"nct_id":"NCT06866210","title":"Risk Analysis of Intracranial Aneurysm Rupture Through Social Determinants of Health","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":1800,"lead_sponsor_name":"Nantes University Hospital","has_results":false},{"nct_id":"NCT03870867","title":"The Emergency Department Falls Study","phase":"","overall_status":"COMPLETED","enrollment_count":1753,"lead_sponsor_name":"Hamilton Health Sciences Corporation","has_results":false},{"nct_id":"NCT06290076","title":"A Predictive Model and Scoring System for Severe Complications After Endovascular Thrombectomy","phase":"","overall_status":"COMPLETED","enrollment_count":1500,"lead_sponsor_name":"Xuanwu Hospital, Beijing","has_results":false},{"nct_id":"NCT06168838","title":"Anticoagulant-associated Intracranial Hemorrhage","phase":"","overall_status":"UNKNOWN","enrollment_count":1200,"lead_sponsor_name":"El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez","has_results":false},{"nct_id":"NCT06784284","title":"PREhospital Prediction of the Risk of Intracranial Hemorrhagic Injury in the Elderly Patient with a Fall","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":1100,"lead_sponsor_name":"University Hospital, Toulouse","has_results":false},{"nct_id":"NCT06494436","title":"Microvention AnEurysm & STroke Real-life Data cOllection","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Microvention-Terumo, Inc.","has_results":false},{"nct_id":"NCT03899350","title":"The Influencing Factors and Prediction Model of Poor Prognosis of Spontaneous Intraparenchymal Hemorrhage","phase":"","overall_status":"UNKNOWN","enrollment_count":1000,"lead_sponsor_name":"Tang-Du Hospital","has_results":false},{"nct_id":"NCT03950076","title":"EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF)","phase":"PHASE4","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":948,"lead_sponsor_name":"Population Health Research Institute","has_results":false},{"nct_id":"NCT06525727","title":"Validation of Falls Decision Rule to Exclude Intracranial Bleeding in Geriatric Fall Patients","phase":"","overall_status":"COMPLETED","enrollment_count":800,"lead_sponsor_name":"Marmara University","has_results":true},{"nct_id":"NCT02811614","title":"Minimally-invasive Surgery Versus Craniotomy in Patients With Supratentorial Hypertensive Intracerebral Hemorrhage","phase":"NA","overall_status":"COMPLETED","enrollment_count":733,"lead_sponsor_name":"Chinese PLA General Hospital","has_results":false},{"nct_id":"NCT07353736","title":"Cerebral Arteriovenous Malformation With Aneurysm: Epidemiology, Clinical Features, and Prognosis","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":630,"lead_sponsor_name":"Duan Chuanzhi","has_results":false},{"nct_id":"NCT06760078","title":"Tranexamic Acid with Intensive Blood Pressure Management in Ultra-Early Intracerebral Hemorrhage","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":532,"lead_sponsor_name":"Xuanwu Hospital, Beijing","has_results":false},{"nct_id":"NCT03484936","title":"Safety and Efficacy of Remote Ischemic Conditioning in Patients With Spontaneous Intracerebral Hemorrhage","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":530,"lead_sponsor_name":"Yi Yang","has_results":false},{"nct_id":"NCT03661528","title":"Trial of Andexanet Alfa in ICrH Patients Receiving an Oral FXa Inhibitor","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":530,"lead_sponsor_name":"Alexion Pharmaceuticals, Inc.","has_results":true},{"nct_id":"NCT05968053","title":"Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi)","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT03815149","title":"Safety and Clinical Effectiveness of Pipeline™ Shield Devices for Intracranial Aneurysms","phase":"","overall_status":"UNKNOWN","enrollment_count":500,"lead_sponsor_name":"Gold Coast Hospital and Health Service","has_results":false},{"nct_id":"NCT05766865","title":"Effect and Safety of Surgical Intervention for Severe Spontaneous Intracerebral Hemorrhage Patients on Long-term Oral Antiplatelet Treatment","phase":"","overall_status":"COMPLETED","enrollment_count":450,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT05975398","title":"China Research for Severe Spontaneous Intracerebral Hemorrhage（CRISIH）","phase":"","overall_status":"UNKNOWN","enrollment_count":450,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT04642443","title":"Evaluate the SENSE Device's Ability to Monitor and Detect Intracranial Hemorrhage","phase":"NA","overall_status":"UNKNOWN","enrollment_count":450,"lead_sponsor_name":"Sense Diagnostics, LLC","has_results":false},{"nct_id":"NCT03772457","title":"Predictive Value of Infarction Volume on Hemorrhagic Transformation in Ischemic Stroke/TIA With Non-valve Atrial Fibrillation(NVAF) Patients Using Rivaroxaban","phase":"","overall_status":"UNKNOWN","enrollment_count":400,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT07387575","title":"Screening in Relatives With Elevated Risk for Unruptured Intracranial Aneurysms","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":300,"lead_sponsor_name":"University of Novi Sad","has_results":false},{"nct_id":"NCT06878066","title":"Thrombolysis in Factor Xa-inhibitors Trial","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Guri Hagberg","has_results":false},{"nct_id":"NCT05361070","title":"Neonatal Seizure Registry, GEnetics of Post-Neonatal Epilepsy","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":300,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT02881957","title":"Hypovitaminosis D in Neurocritical Patients","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":274,"lead_sponsor_name":"University of Utah","has_results":true},{"nct_id":"NCT07088250","title":"Statins for Treatment of Primary Intracerebral Hemorrhage","phase":"NA","overall_status":"RECRUITING","enrollment_count":264,"lead_sponsor_name":"The Second Hospital of Anhui Medical University","has_results":false},{"nct_id":"NCT05871528","title":"Registry of Patients With Remote Posterior cErebral Hemorrhage Following Reperfusion Treatment in Ischemic Stroke","phase":"","overall_status":"UNKNOWN","enrollment_count":250,"lead_sponsor_name":"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau","has_results":false},{"nct_id":"NCT06136078","title":"Appropriateness of Methodist Health System(MHS) Inter-facility Transfers of Traumatic Intracranial Subarachnoid Hemorrhage and Spontaneous Bleeds for Level-1 Advanced Surgical Intervention","phase":"","overall_status":"UNKNOWN","enrollment_count":250,"lead_sponsor_name":"Methodist Health System","has_results":false},{"nct_id":"NCT04459806","title":"Intracranial PrEssure Time dOse (ImPETO)","phase":"","overall_status":"RECRUITING","enrollment_count":250,"lead_sponsor_name":"University of Milano Bicocca","has_results":false},{"nct_id":"NCT05609734","title":"No Cases of Delayed Intracranial Hemorrhage (d-ICH) Among Patients With Mild Traumatic Brain Injury (mTBI) on Oral Anticoagulation Therapy","phase":"","overall_status":"COMPLETED","enrollment_count":249,"lead_sponsor_name":"Umeå University","has_results":false},{"nct_id":"NCT06635564","title":"Personalized ViscoElastic Testing-guided Bleeding Management In Liver Surgery, Neurosurgery and Obstetrics","phase":"","overall_status":"RECRUITING","enrollment_count":240,"lead_sponsor_name":"Medical University of Vienna","has_results":false},{"nct_id":"NCT03969732","title":"Multimodal Biomarkers for Diagnosis and Prognosis in CAA","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":240,"lead_sponsor_name":"National Taiwan University Hospital","has_results":false},{"nct_id":"NCT04983953","title":"Evaluation of Clinical Decision Support System for Intracranial Hemorrhage Using Brain CT Images","phase":"","overall_status":"COMPLETED","enrollment_count":236,"lead_sponsor_name":"Heuron Inc.","has_results":false},{"nct_id":"NCT06036732","title":"A New Approach in Intensive Care Unit Consciousness Assessment: FIVE Score","phase":"","overall_status":"UNKNOWN","enrollment_count":223,"lead_sponsor_name":"Istanbul University - Cerrahpasa","has_results":false},{"nct_id":"NCT06101537","title":"Correlation Patterns of Brain Temperature-Pressure in Acute Brain Injury","phase":"","overall_status":"COMPLETED","enrollment_count":208,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT05300672","title":"Fibrinogen Replacement to Prevent Intracranial Haemorrhage in Ischemic Stroke Patients After Thrombolysis (FibER)","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":207,"lead_sponsor_name":"Azienda Usl di Bologna","has_results":false},{"nct_id":"NCT03153150","title":"Start or STop Anticoagulants Randomised Trial (SoSTART)","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":203,"lead_sponsor_name":"University of Edinburgh","has_results":false},{"nct_id":"NCT05593380","title":"Bleeding Intracerebral Hemorrhage With Early Invasive Intracranial Pressure Monitoring Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":193,"lead_sponsor_name":"Xiangya Hospital of Central South University","has_results":false},{"nct_id":"NCT04337697","title":"Neonatal Seizure Registry - Developmental Functional EValuation","phase":"","overall_status":"COMPLETED","enrollment_count":188,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT05419193","title":"PROpranolol for Cerebral Hemorrhage-ASsociated pnEumonia (PRO-CHASE)","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":168,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT07115459","title":"Development and Validation of a Prognostic Model for Neurocritical Patients Using Multimodal Brain Monitoring","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":167,"lead_sponsor_name":"Xiangya Hospital of Central South University","has_results":false},{"nct_id":"NCT03542656","title":"Application of Amyloid PET in Cerebral Amyloid Angiopathy","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":160,"lead_sponsor_name":"National Taiwan University Hospital","has_results":false},{"nct_id":"NCT06283901","title":"Improving Diagnosis and Prediction of Outcome in Patients With Severe Disorders of Consciousness","phase":"","overall_status":"UNKNOWN","enrollment_count":160,"lead_sponsor_name":"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}