{"disease":{"id":"inhalation","name":"inhalation"},"drugs":{"marketed":[{"drug_id":"fusidic-acid","indication_name":"Inhalational anthrax","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Ramycin","generic_name":"FUSIDIC ACID","company_name":"","drug_phase":"phase_3","molecular_target":"Bile salt export pump","drug_class":"fusidic acid","quality_score":47,"revenue":null,"mechanism":"Fusidic acid works by inhibiting the function of the bacterial ribosome, preventing the production of essential proteins."},{"drug_id":"doxycyclin","indication_name":"Inhalational anthrax","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"Doxycyclin","company_name":"Bulovka Hospital","drug_phase":"marketed","molecular_target":"72 kDa type IV collagenase, Stromelysin-1, Collagenase 3","drug_class":"","quality_score":19,"revenue":null,"mechanism":null},{"drug_id":"benzylpenicillin","indication_name":"Inhalational anthrax","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Penicillin G Potassium In Plastic Container","generic_name":"Benzylpenicillin","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"","drug_class":"Penicillin-class Antibacterial","quality_score":32,"revenue":null,"mechanism":""},{"drug_id":"obiltoxaximab","indication_name":"Inhalational anthrax","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Anthim","generic_name":"OBILTOXAXIMAB","company_name":"Elusys Therapeutics Inc","drug_phase":"marketed","molecular_target":"","drug_class":"Anthrax Protective Antigen-directed Antibody [EPC]","quality_score":10,"revenue":null,"mechanism":"Anthim works by binding to the protective antigen of anthrax toxin, neutralizing its effects."},{"drug_id":"doxycycline","indication_name":"Inhalational anthrax","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Vibramycin","generic_name":"doxycycline","company_name":"Generic (originally Pfizer)","drug_phase":"marketed","molecular_target":"72 kDa type IV collagenase, Stromelysin-1, Collagenase 3","drug_class":"Tetracycline antibiotic","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"penicillin","indication_name":"Inhalational anthrax","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"penicillin","company_name":"Karlstad University","drug_phase":"marketed","molecular_target":"Bacterial penicillin-binding protein, Beta-lactamase, Beta-lactamase TEM","drug_class":"","quality_score":null,"revenue":null,"mechanism":null}],"pipeline":[],"offLabel":[],"totalMarketed":6,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05198492","title":"Short- and Long-term Health Effects of Air Pollution in Poland","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":8300000,"lead_sponsor_name":"Medical University of Bialystok","has_results":false},{"nct_id":"NCT04541498","title":"Impact of Air Pollution and Climate Changes on the Epidemiology of Cardiovascular Disease","phase":"","overall_status":"COMPLETED","enrollment_count":150000,"lead_sponsor_name":"Medical University of Bialystok","has_results":false},{"nct_id":"NCT04353232","title":"Impact of Lifetime Exposure to Air and Noise Pollution on Cardiovascular Disease and Mortality - the AIRCARD Study.","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":33723,"lead_sponsor_name":"Odense University Hospital","has_results":false},{"nct_id":"NCT03594643","title":"Electronic Cigarette and Surgery (ECigarSurg)","phase":"","overall_status":"COMPLETED","enrollment_count":1700,"lead_sponsor_name":"Centre Hospitalier Universitaire de Nīmes","has_results":false},{"nct_id":"NCT02660411","title":"Impact of Anesthesia Maintenance Methods on Long-term Survival","phase":"NA","overall_status":"COMPLETED","enrollment_count":1228,"lead_sponsor_name":"Peking University First Hospital","has_results":false},{"nct_id":"NCT05343260","title":"Impact of Anesthesia Maintenance Methods on 5-year Survival After Surgery","phase":"NA","overall_status":"COMPLETED","enrollment_count":1228,"lead_sponsor_name":"Peking University First Hospital","has_results":false},{"nct_id":"NCT01169155","title":"Critical Smoke Alarm Characteristics to Awaken Children From Stage 4 Sleep","phase":"NA","overall_status":"COMPLETED","enrollment_count":834,"lead_sponsor_name":"Nationwide Children's Hospital","has_results":false},{"nct_id":"NCT03558646","title":"Impact of Hydroxocobalamine on Outcome of Smoke Inhalation Injury Admitted to the ICU","phase":"","overall_status":"COMPLETED","enrollment_count":739,"lead_sponsor_name":"Saint-Louis Hospital, Paris, France","has_results":false},{"nct_id":"NCT03834246","title":"Smoke Inhalation Injury in Patients Admitted to Intensive Care","phase":"","overall_status":"UNKNOWN","enrollment_count":700,"lead_sponsor_name":"Centre d'Investigation Clinique et Technologique 805","has_results":false},{"nct_id":"NCT07004699","title":"Comparison of Two Ventilation Methods During Endoscopy of the Pharynx, Larynx and Oesophagus","phase":"NA","overall_status":"RECRUITING","enrollment_count":610,"lead_sponsor_name":"Poitiers University Hospital","has_results":false},{"nct_id":"NCT05819996","title":"Addressing Tetrachloroethylene Exposure in an Impacted Community","phase":"NA","overall_status":"RECRUITING","enrollment_count":510,"lead_sponsor_name":"Purdue University","has_results":false},{"nct_id":"NCT04210570","title":"Decreasing Environmental Impact and Costs of Using Inhalational Anesthetic With a Carbon Dioxide Membrane Filter System","phase":"NA","overall_status":"UNKNOWN","enrollment_count":510,"lead_sponsor_name":"Western University, Canada","has_results":false},{"nct_id":"NCT02533908","title":"Combination of Nitrous Oxide 70% With Fentanyl Intranasal for Procedural Analgosedation in Children","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":402,"lead_sponsor_name":"University Children's Hospital, Zurich","has_results":false},{"nct_id":"NCT03275935","title":"Evaluation of Inhalation Technique in Patients With COPD, Asthma or ACOS Using a Dry Powder Device (DPI)","phase":"","overall_status":"COMPLETED","enrollment_count":307,"lead_sponsor_name":"Kathmandu University School of Medical Sciences","has_results":false},{"nct_id":"NCT01929226","title":"Safety, Tolerability, and PK of a Single Intravenous Dose of ETI-204 in Adult Volunteers","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":280,"lead_sponsor_name":"Elusys Therapeutics","has_results":true},{"nct_id":"NCT05548998","title":"Effect of Low Flow Anesthetics on Neurocognitive Decline in the Elderly","phase":"","overall_status":"COMPLETED","enrollment_count":230,"lead_sponsor_name":"Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization","has_results":false},{"nct_id":"NCT07123870","title":"Effect of Combined Intravenous-Inhalational Anesthesia (CIVIA) on Postoperative Recovery Patterns.","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":210,"lead_sponsor_name":"Kocaeli City Hospital","has_results":false},{"nct_id":"NCT06624696","title":"Inhaling Penehyclidine to Prevent Perioperative Respiratory Adverse Events in Children at Risk Undergoing Sevoflurane Anesthesia","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":204,"lead_sponsor_name":"Sun Yat-sen University","has_results":false},{"nct_id":"NCT06561282","title":"Predictive Role of Glucose/Potassium Ratio on Mortality in Major Burns.","phase":"","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Konya Meram State Hospital","has_results":false},{"nct_id":"NCT05025215","title":"The Effect of Precise Aerosol Inhalation Nursing on Sputum Excretion in Elderly Patients With Lung Surgery","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"The First Affiliated Hospital of Soochow University","has_results":false},{"nct_id":"NCT03396094","title":"Pre- and Apnoeic Oxygenation for RSI in ED","phase":"NA","overall_status":"COMPLETED","enrollment_count":192,"lead_sponsor_name":"National University Hospital, Singapore","has_results":false},{"nct_id":"NCT02862314","title":"PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":167,"lead_sponsor_name":"Centre Hospitalier Universitaire de Besancon","has_results":false},{"nct_id":"NCT03495947","title":"High Flow Nasal Cannula in Immediately Post Extubation","phase":"","overall_status":"COMPLETED","enrollment_count":165,"lead_sponsor_name":"Hospital Italiano de Buenos Aires","has_results":false},{"nct_id":"NCT04273035","title":"Handheld-multimedia Versus Oral Midazolam in Pediatric on Perioperative Anxiety","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"Universitair Ziekenhuis Brussel","has_results":false},{"nct_id":"NCT03795259","title":"Effect of Rocuronium and Sugammadex Under Sevoflurane and Desflurane Anesthesia in Children","phase":"NA","overall_status":"COMPLETED","enrollment_count":148,"lead_sponsor_name":"Istanbul University","has_results":false},{"nct_id":"NCT03764696","title":"Maternal Oxygen Administration for Fetal Distress II","phase":"NA","overall_status":"COMPLETED","enrollment_count":140,"lead_sponsor_name":"Navy General Hospital, Beijing","has_results":false},{"nct_id":"NCT06510166","title":"The Effect of Distraction Methods Used During Inhalation Therapy on Children's Fear and Anxiety","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":120,"lead_sponsor_name":"Ondokuz Mayıs University","has_results":false},{"nct_id":"NCT04125108","title":"The Effect of a Pulmonary Rehabilitation on Lung Function and Exercise Capacity in Patients With Burn","phase":"NA","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"Hangang Sacred Heart Hospital","has_results":false},{"nct_id":"NCT01194024","title":"Scoring System for Inhalation Injury","phase":"","overall_status":"COMPLETED","enrollment_count":108,"lead_sponsor_name":"American Burn Association","has_results":false},{"nct_id":"NCT04036487","title":"Effects of General Anesthesia on Quality of Recovery After Transaxillary Endoscopic Breast Augmentation","phase":"NA","overall_status":"COMPLETED","enrollment_count":104,"lead_sponsor_name":"Chih-Cheng Hung","has_results":false},{"nct_id":"NCT03581006","title":"Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Trial","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"NYU Langone Health","has_results":false},{"nct_id":"NCT05242939","title":"Active and Passive Distraction Techniques","phase":"NA","overall_status":"COMPLETED","enrollment_count":99,"lead_sponsor_name":"Akdeniz University","has_results":false},{"nct_id":"NCT07073625","title":"During Inhaler Application, Children Were Given Stress Ball and Storybook Reading Interventions","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":99,"lead_sponsor_name":"Ataturk University","has_results":false},{"nct_id":"NCT04079309","title":"Anxiolytic Effects of Lavender and Orange Oil","phase":"NA","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Ankara University","has_results":false},{"nct_id":"NCT06024733","title":"Intravenous Anesthesia by Targeted Controlled Infusion Versus Inhalational Anesthesia on the Surgical Stress Response","phase":"PHASE4","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":90,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT05886998","title":"Nebulized Heparin for Prevention of Acute Lung Injury in Smoke Inhalation Injury","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":88,"lead_sponsor_name":"Ain Shams University","has_results":false},{"nct_id":"NCT06326593","title":"Wii Aerobic Training in Inhalation-injury Children Post-thermal Burn","phase":"NA","overall_status":"COMPLETED","enrollment_count":80,"lead_sponsor_name":"MTI University","has_results":false},{"nct_id":"NCT06297356","title":"The Effect of Stress Ball Utilisation on Treatment Duration, Dyspnea Severity and Anxiety Level in Nebuliser Therapy","phase":"NA","overall_status":"UNKNOWN","enrollment_count":80,"lead_sponsor_name":"Kirsehir Ahi Evran Universitesi","has_results":false},{"nct_id":"NCT05891886","title":"Supplemental Oxygen in Pulmonary Embolism (SO-PE)","phase":"EARLY_PHASE1","overall_status":"RECRUITING","enrollment_count":80,"lead_sponsor_name":"Massachusetts General Hospital","has_results":false},{"nct_id":"NCT06197646","title":"Inhalation Therapy and Therapeutic Play","phase":"NA","overall_status":"COMPLETED","enrollment_count":80,"lead_sponsor_name":"Istinye University","has_results":false},{"nct_id":"NCT05906225","title":"Anesthesia and EEG Discontinuity in Infants","phase":"NA","overall_status":"UNKNOWN","enrollment_count":78,"lead_sponsor_name":"Seoul National University Hospital","has_results":false},{"nct_id":"NCT04645316","title":"The Effect of Sevoflurane and Desflurane on Clara Cell Protein on the Lung","phase":"NA","overall_status":"COMPLETED","enrollment_count":72,"lead_sponsor_name":"Inonu University","has_results":false},{"nct_id":"NCT07325799","title":"Anesthesia Type and Postoperative Sleep Quality in Septoplasty","phase":"","overall_status":"RECRUITING","enrollment_count":72,"lead_sponsor_name":"Elazıg Fethi Sekin Sehir Hastanesi","has_results":false},{"nct_id":"NCT05529641","title":"Effects of Diaphragmatic Resistance Training in People With Chronic Neck Pain.","phase":"NA","overall_status":"COMPLETED","enrollment_count":71,"lead_sponsor_name":"National Cheng Kung University","has_results":false},{"nct_id":"NCT05861232","title":"The Effect of Watching Informative Animation on Fear and Anxiety in Children","phase":"NA","overall_status":"UNKNOWN","enrollment_count":70,"lead_sponsor_name":"Mukader Kaya","has_results":false},{"nct_id":"NCT01932242","title":"Safety, Tolerability and PK of Repeat Administration of Intravenous ETI-204 in Adult Volunteers","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":70,"lead_sponsor_name":"Elusys Therapeutics","has_results":true},{"nct_id":"NCT06250452","title":"Effect of Halotherapy in Children With Asthma","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":70,"lead_sponsor_name":"Igdir University","has_results":false},{"nct_id":"NCT04013256","title":"Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke","phase":"NA","overall_status":"SUSPENDED","enrollment_count":66,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT06320743","title":"Cerebral and Peripheral Near Infrared Spectroscopy Monitoring in Low and High Flow Anaesthesia in Pediatric","phase":"NA","overall_status":"COMPLETED","enrollment_count":66,"lead_sponsor_name":"Ankara City Hospital Bilkent","has_results":false},{"nct_id":"NCT07248917","title":"Evaluation of Sevoflurane Consumption During Initial Phase of Minimal-Flow Anesthesia in Retrograde Intrarenal Surgery","phase":"NA","overall_status":"COMPLETED","enrollment_count":62,"lead_sponsor_name":"Dr. Lutfi Kirdar Kartal Training and Research Hospital","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}