{"disease":{"id":"induction-of-general-anesthesia","name":"Induction of general anesthesia","therapeutic_area":"","data":{},"enrichment_level":0,"last_enriched_at":null,"visit_count":0,"created_at":"2026-04-19T18:31:21.150Z","updated_at":"2026-04-19T18:39:44.960Z","meddra_pt":null,"meddra_code":null,"icd10_codes":null,"synonyms":[],"prevalence_global":null,"prevalence_us":null,"marketed_drug_count":2,"pipeline_drug_count":0,"trial_count":0},"drugs":{"marketed":[{"drug_id":"sevoflurane","indication_name":"Induction and maintenance of general anesthesia","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"SEVOFLURANE","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"General Anesthetic [EPC]","quality_score":10,"revenue":null,"mechanism":null},{"drug_id":"sevoflurane","indication_name":"Induction and maintenance of general anesthesia","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"SEVOFLURANE","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"General Anesthetic [EPC]","quality_score":10,"revenue":null,"mechanism":null},{"drug_id":"chembl-chembl526","indication_name":"Induction of General Anesthesia","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"PROPOFOL","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"General Anesthetic [EPC]","quality_score":30,"revenue":null,"mechanism":null},{"drug_id":"flutoprazepam","indication_name":"Induction of general anesthesia","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Restas","generic_name":"FLUTOPRAZEPAM","company_name":"","drug_phase":"phase_2","molecular_target":"","drug_class":"flutoprazepam","quality_score":null,"revenue":null,"mechanism":"Flutoprazepam works by enhancing the activity of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain."},{"drug_id":"amidate","indication_name":"Induction of general anesthesia","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Amidate","generic_name":"Etomidate","company_name":"Pfizer Inc.","drug_phase":"marketed","molecular_target":"GABA A receptor alpha-2/beta-2/gamma-2","drug_class":"General Anesthetic [EPC]","quality_score":60,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":5,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06773351","title":"A Response Surface Analysis for the Interaction Between Ciprofol and Sevoflurane","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":300,"lead_sponsor_name":"Feng Gao","has_results":false},{"nct_id":"NCT07294040","title":"Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Cancer Patients","phase":"","overall_status":"RECRUITING","enrollment_count":140,"lead_sponsor_name":"Dolunay ARIK","has_results":false},{"nct_id":"NCT04511728","title":"A Study to Evaluate the Efficacy and Safety of HSK3486 in the Induction of General Anesthesia","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":129,"lead_sponsor_name":"Haisco Pharmaceutical Group Co., Ltd.","has_results":false},{"nct_id":"NCT05105022","title":"Propofol Versus Sevoflurane for Induction of GA in Infants","phase":"NA","overall_status":"UNKNOWN","enrollment_count":122,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT05502211","title":"A Comparison Between Ketamine-lidocaine Versus Ketamine-fentanyl for Induction on the Hemodynamic Effects in Patients With Coronary Artery Disease","phase":"NA","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Kasr El Aini Hospital","has_results":false},{"nct_id":"NCT06204653","title":"Effect of High-flow Nasal Oxygenation on Gastric Insufflation in Children","phase":"NA","overall_status":"UNKNOWN","enrollment_count":70,"lead_sponsor_name":"Ajou University School of Medicine","has_results":false},{"nct_id":"NCT04048811","title":"A Clinical Trial Evaluating the Efficacy and Safety of HSK3486 Injectable Emulsion in Elective Surgery Patients","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":46,"lead_sponsor_name":"Sichuan Haisco Pharmaceutical Group Co., Ltd","has_results":false}],"total":7},"guidelines":[{"drug_id":"amidate","guideline_body":"FDA label","recommendation":"Etomidate Injection is indicated by intravenous injection for the induction of general anesthesia.","line_of_therapy":"1L","evidence_grade":"A","guideline_year":null}],"source":"Drug Landscape verified database"}