{"disease":{"id":"ict","name":"ict"},"drugs":{"marketed":[{"drug_id":"fragmin","indication_name":"Prophylaxis of DVT in Medical Patients with Restricted Mobility","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Fragmin","generic_name":"Dalteparin Sodium","company_name":"Pfizer Inc.","drug_phase":"marketed","molecular_target":"Factor Xa and thrombin","drug_class":"Low molecular weight heparin (LMWH)","quality_score":68,"revenue":null,"mechanism":"Dalteparin enhances inhibition of Factor Xa and thrombin by antithrombin."},{"drug_id":"corn-starch","indication_name":"Protecting Against Irritating Friction","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"Corn starch","company_name":"Peking University People's Hospital","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":9,"revenue":null,"mechanism":null},{"drug_id":"aldactone","indication_name":"Edema in cirrhotic patients unresponsive to fluid and sodium restriction","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Aldactone","generic_name":"Spironolactone","company_name":"Pfizer Inc.","drug_phase":"marketed","molecular_target":"Aldosterone receptors at aldosterone-dependent sodium-potassium exchange site in distal convoluted renal tubule","drug_class":"Potassium-sparing diuretic, aldosterone antagonist","quality_score":66,"revenue":null,"mechanism":"Aldosterone antagonist causing increased sodium and water excretion while retaining potassium."},{"drug_id":"fragmin","indication_name":"Prophylaxis of deep vein thrombosis in medical patients with severely restricted mobility during acute illness","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Fragmin","generic_name":"Dalteparin Sodium","company_name":"Pfizer Inc.","drug_phase":"marketed","molecular_target":"Factor Xa and thrombin","drug_class":"Low molecular weight heparin (LMWH)","quality_score":68,"revenue":null,"mechanism":"Dalteparin enhances inhibition of Factor Xa and thrombin by antithrombin."}],"pipeline":[],"offLabel":[],"totalMarketed":4,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06140823","title":"Prospective Validation of Liver Cancer Risk Computation (LIRIC) Models","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":6000000,"lead_sponsor_name":"Beth Israel Deaconess Medical Center","has_results":false},{"nct_id":"NCT07188636","title":"Prediction of Postoperative Mortality in Patients Undergoing Non-cardiac Surgery: Development and Validation of the Surgical Mortality Model","phase":"","overall_status":"COMPLETED","enrollment_count":642377,"lead_sponsor_name":"Asan Medical Center","has_results":false},{"nct_id":"NCT03354546","title":"Development and Validation of a Preoperative Frailty Index Using Health Administrative Data","phase":"","overall_status":"COMPLETED","enrollment_count":511285,"lead_sponsor_name":"Ottawa Hospital Research Institute","has_results":true},{"nct_id":"NCT06978348","title":"Research on Early Prediction Model of Ischemic Cerebrovascular Disease Based on Artificial Intelligence Technology.","phase":"","overall_status":"RECRUITING","enrollment_count":244296,"lead_sponsor_name":"Shanghai Jiao Tong University School of Medicine","has_results":false},{"nct_id":"NCT02668549","title":"Cross-Sectional Study to Define and Validate \"Doctor/Pharmacy Shopping\" as Outcomes Suggestive of Abuse and/or Addiction","phase":"","overall_status":"COMPLETED","enrollment_count":164923,"lead_sponsor_name":"Member Companies of the Opioid PMR Consortium","has_results":false},{"nct_id":"NCT06597838","title":"Development and Validation of a Real-time Prediction Model for Acute Kidney Injury in Hospitalized Patients","phase":"","overall_status":"RECRUITING","enrollment_count":161876,"lead_sponsor_name":"Peking University First Hospital","has_results":false},{"nct_id":"NCT05558423","title":"ZOE Health Study: The Intermittent Fasting Study","phase":"NA","overall_status":"UNKNOWN","enrollment_count":150000,"lead_sponsor_name":"Zoe Global Limited","has_results":false},{"nct_id":"NCT05150548","title":"Predictive Time-to-Event Model for Major Medical Complications After Colectomy","phase":"","overall_status":"UNKNOWN","enrollment_count":130000,"lead_sponsor_name":"University of British Columbia","has_results":false},{"nct_id":"NCT04504162","title":"Monitoring and Risk Prediction of Iatrogenic Sedative Hypnotics Addiction in a Shanghai Psychiatric Hospital","phase":"","overall_status":"UNKNOWN","enrollment_count":100000,"lead_sponsor_name":"Shanghai Mental Health Center","has_results":false},{"nct_id":"NCT05142644","title":"IUGR; Cause and Relationship","phase":"","overall_status":"COMPLETED","enrollment_count":80000,"lead_sponsor_name":"Karolinska Institutet","has_results":false},{"nct_id":"NCT03662178","title":"Investigating the Structured Use of Ultrasound Scanning for Fetal Growth","phase":"","overall_status":"RECRUITING","enrollment_count":56000,"lead_sponsor_name":"Oxford University Hospitals NHS Trust","has_results":false},{"nct_id":"NCT04973202","title":"Portrayal of Hospital Alcohol Detoxification in France","phase":"","overall_status":"COMPLETED","enrollment_count":50000,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT06547281","title":"Machine Learning Prediction of Multiple Infections in Elderly Surgical Patients","phase":"","overall_status":"COMPLETED","enrollment_count":42540,"lead_sponsor_name":"Weidong Mi","has_results":false},{"nct_id":"NCT06612177","title":"Elderly Patients Surgical Site Infection Phenotypes Identification","phase":"","overall_status":"COMPLETED","enrollment_count":42532,"lead_sponsor_name":"Weidong Mi","has_results":false},{"nct_id":"NCT06265493","title":"Postoperative Infectious Complications Calculator for Elderly Patients","phase":"","overall_status":"COMPLETED","enrollment_count":37230,"lead_sponsor_name":"Weidong Mi","has_results":false},{"nct_id":"NCT06653374","title":"Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns","phase":"","overall_status":"COMPLETED","enrollment_count":26000,"lead_sponsor_name":"HOSPITAL GINECO OBSTETRICO ISIDRO AYORA","has_results":false},{"nct_id":"NCT05540119","title":"Swedish Oesophago-Gastric Study","phase":"","overall_status":"UNKNOWN","enrollment_count":25000,"lead_sponsor_name":"Karolinska Institutet","has_results":false},{"nct_id":"NCT04336605","title":"Killing Pain - Use of Analgesic, Sedative and Anxiolytic Medication and the Development of Psychiatric Illness in Adolescents","phase":"","overall_status":"UNKNOWN","enrollment_count":25000,"lead_sponsor_name":"Norwegian Center for Violence and Traumatic Stress Studies","has_results":false},{"nct_id":"NCT03180060","title":"Meta-Analysis of Stress Myocardial Perfusion Imaging","phase":"","overall_status":"COMPLETED","enrollment_count":23051,"lead_sponsor_name":"American British Cowdray Medical Center","has_results":false},{"nct_id":"NCT05860660","title":"Screens, Virtual Reality and Digital Addiction (EVADD)","phase":"","overall_status":"COMPLETED","enrollment_count":21000,"lead_sponsor_name":"Institut Rafael","has_results":false},{"nct_id":"NCT06594913","title":"Eating Disorders Genetics Initiative 2","phase":"","overall_status":"RECRUITING","enrollment_count":20000,"lead_sponsor_name":"University of North Carolina, Chapel Hill","has_results":false},{"nct_id":"NCT06607471","title":"Multimodal and Multidisciplinary Approach to Optimize Diagnostic, Prognostic, and Therapeutic Management of Patients with Non-ischemic Cardiomyopathies and Arrhythmogenic-inflammatory Phenotypes: a Multicenter, Observational, Retrospective and Prospective Registry Study.","phase":"","overall_status":"RECRUITING","enrollment_count":15000,"lead_sponsor_name":"Scientific Institute San Raffaele","has_results":false},{"nct_id":"NCT04185779","title":"COLO-COHORT (Colorectal Cancer Cohort) Study","phase":"","overall_status":"RECRUITING","enrollment_count":15000,"lead_sponsor_name":"South Tyneside and Sunderland NHS Foundation Trust","has_results":false},{"nct_id":"NCT06705205","title":"Short, Animated Storytelling (SAS) for Addiction Stigma Reduction","phase":"NA","overall_status":"COMPLETED","enrollment_count":13397,"lead_sponsor_name":"Stanford University","has_results":false},{"nct_id":"NCT05385874","title":"Risk Prediction and Its Intelligent Assessment for Cognitive Impairment Among Community-dwelling Older Adults","phase":"","overall_status":"COMPLETED","enrollment_count":13228,"lead_sponsor_name":"Peking University Sixth Hospital","has_results":false},{"nct_id":"NCT07249970","title":"Understanding the Long-term Paths of People With Addictions","phase":"","overall_status":"RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Centre Hospitalier Charles Perrens, Bordeaux","has_results":false},{"nct_id":"NCT04806620","title":"Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research","phase":"","overall_status":"RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Brain Inflammation Collaborative","has_results":false},{"nct_id":"NCT06074601","title":"MIRACLE of LIFE Study","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Mirvie","has_results":false},{"nct_id":"NCT03398629","title":"Diagnosis and Management of Intrauterine Growth Restriction and Congenital Anomalies","phase":"","overall_status":"RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Guangzhou Women and Children's Medical Center","has_results":false},{"nct_id":"NCT04766866","title":"sFlt1/PlGF and Planned Delivery to Prevent Preeclampsia at Term.","phase":"NA","overall_status":"RECRUITING","enrollment_count":9132,"lead_sponsor_name":"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau","has_results":false},{"nct_id":"NCT01036971","title":"Screening Protocol for the Evaluation of Potential Research Subjects","phase":"","overall_status":"COMPLETED","enrollment_count":6967,"lead_sponsor_name":"National Institute on Drug Abuse (NIDA)","has_results":false},{"nct_id":"NCT06926153","title":"Interventional Study on Smoking Reduction in Psychiatry","phase":"NA","overall_status":"RECRUITING","enrollment_count":6500,"lead_sponsor_name":"GCS-CCOMS","has_results":false},{"nct_id":"NCT05600504","title":"Development and Validation of a Prediction Model for Depression and Anxiety in Perioperative Elderly Adults","phase":"","overall_status":"COMPLETED","enrollment_count":6386,"lead_sponsor_name":"Chinese PLA General Hospital","has_results":false},{"nct_id":"NCT06979856","title":"Short, Animated Storytelling (SAS) Videos to Reduce Smartphone Addiction in the US","phase":"NA","overall_status":"COMPLETED","enrollment_count":6000,"lead_sponsor_name":"Stanford University","has_results":false},{"nct_id":"NCT07494422","title":"A Path to Prevention of Elder Abuse in Long-term Care. Prevalence Study Among Staff in Long-term Care.","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":6000,"lead_sponsor_name":"Linkoeping University","has_results":false},{"nct_id":"NCT06166641","title":"Prediction Models for Risk Score and Prognosis of Intraoperatively Acquired Pressure Injury in Surgical Patients","phase":"","overall_status":"UNKNOWN","enrollment_count":5658,"lead_sponsor_name":"Affiliated Hospital of Guangdong Medical University","has_results":false},{"nct_id":"NCT06641986","title":"A Prediction Model of Postoperative Anxiety Symptom in Elderly Patients Undergoing Major Noncardiac Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":5551,"lead_sponsor_name":"Chinese PLA General Hospital","has_results":false},{"nct_id":"NCT06527703","title":"An International Prospective, Observational, Multi-centre Study on the Duration of Pre-operative Liquid Fasting","phase":"","overall_status":"COMPLETED","enrollment_count":5100,"lead_sponsor_name":"Mater Dei Hospital, Malta","has_results":false},{"nct_id":"NCT07135024","title":"Prospective Register Study to Assess Eligibility for and Efficacy of Surgical Treatment in Patients With nEuRovascular Conflict","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":5001,"lead_sponsor_name":"Gerrit A Schubert","has_results":false},{"nct_id":"NCT06748261","title":"AI-enabled Screening and Diagnosis of Cardiomyopathies Using Coronary CTA","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":5000,"lead_sponsor_name":"Shanghai Zhongshan Hospital","has_results":false},{"nct_id":"NCT05463796","title":"InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer","phase":"","overall_status":"RECRUITING","enrollment_count":5000,"lead_sponsor_name":"Dana-Farber Cancer Institute","has_results":false},{"nct_id":"NCT07020273","title":"CONNECT Cancer Survivors With Tobacco Treatment","phase":"NA","overall_status":"RECRUITING","enrollment_count":5000,"lead_sponsor_name":"Washington University School of Medicine","has_results":false},{"nct_id":"NCT06621485","title":"Calculator Predicts Early Mortality Post Hepatocellular Carcinoma Resection","phase":"","overall_status":"COMPLETED","enrollment_count":4966,"lead_sponsor_name":"Beijing Tsinghua Chang Gung Hospital","has_results":false},{"nct_id":"NCT04902300","title":"Prevalence of Internet Addiction Among Adolescent","phase":"","overall_status":"UNKNOWN","enrollment_count":4750,"lead_sponsor_name":"Université de Reims Champagne-Ardenne","has_results":false},{"nct_id":"NCT07174700","title":"Prevalence of Behavioral Addiction and Its Relation With Psychological Disturbance","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":4600,"lead_sponsor_name":"Zagazig University","has_results":false},{"nct_id":"NCT05536245","title":"Analysis of the Prevalence of Violence Suffered or Committed by Patients Suffering From Addiction in a Care Facility","phase":"","overall_status":"COMPLETED","enrollment_count":4500,"lead_sponsor_name":"Centre Hospitalier Universitaire de Nīmes","has_results":false},{"nct_id":"NCT06930820","title":"In-Hospital Electronic Registry of Severe Trauma of the Fondazione I.R.C.C.S. Policlinico San Matteo","phase":"","overall_status":"RECRUITING","enrollment_count":4000,"lead_sponsor_name":"Fondazione IRCCS Policlinico San Matteo di Pavia","has_results":false},{"nct_id":"NCT02751762","title":"A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Opioids for the Treatment of Chronic Pain","phase":"","overall_status":"COMPLETED","enrollment_count":3600,"lead_sponsor_name":"Member Companies of the Opioid PMR Consortium","has_results":false},{"nct_id":"NCT06697171","title":"Effectiveness of Conflict-of-interest Disclosures on Trust, Credibility and Transparency When Displayed on Social Media Posts From Registered Dietitians","phase":"NA","overall_status":"COMPLETED","enrollment_count":3409,"lead_sponsor_name":"University of Ontario Institute of Technology","has_results":false},{"nct_id":"NCT02349321","title":"Skhokho Supporting Success: A Cluster RCT of a Multi-faceted, School-based IPV Prevention Intervention in South Africa","phase":"NA","overall_status":"COMPLETED","enrollment_count":3192,"lead_sponsor_name":"Medical Research Council, South Africa","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}