{"disease":{"id":"ibs","name":"ibs"},"drugs":{"marketed":[{"drug_id":"tenapanor","indication_name":"Irritable Bowel Syndrome with Constipation (IBS-C)","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"TENAPANOR","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":30,"revenue":null,"mechanism":null}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04905524","title":"Activity Changes in Irritable Bowel Syndrome (IBS), Anxiety, and Depression Following the Use of Viome Precision Nutrition Program (VPNP)","phase":"NA","overall_status":"COMPLETED","enrollment_count":10000,"lead_sponsor_name":"Viome","has_results":false},{"nct_id":"NCT03131414","title":"The IMAGINE-SPOR CIHR Chronic Disease Network","phase":"","overall_status":"UNKNOWN","enrollment_count":8000,"lead_sponsor_name":"Hamilton Health Sciences Corporation","has_results":false},{"nct_id":"NCT07261826","title":"Real-World Study on Fecal Microbiota Transplantation: Long-Term Effectiveness and Safety Statistics","phase":"","overall_status":"RECRUITING","enrollment_count":4000,"lead_sponsor_name":"Chen QiYi","has_results":false},{"nct_id":"NCT04462900","title":"Evaluate the Safety of Linaclotide in IBS-C Patients in China","phase":"","overall_status":"COMPLETED","enrollment_count":3028,"lead_sponsor_name":"AstraZeneca","has_results":false},{"nct_id":"NCT04817683","title":"Study on the Relationship Between Mobile Phone Addiction and Functional Gastrointestinal Disorders","phase":"","overall_status":"COMPLETED","enrollment_count":3000,"lead_sponsor_name":"Second Affiliated Hospital of Xi'an Jiaotong University","has_results":false},{"nct_id":"NCT02955316","title":"Irritable Bowel Syndrome Survey in Gastroenterological Adult Outpatients in China","phase":"","overall_status":"COMPLETED","enrollment_count":3000,"lead_sponsor_name":"AstraZeneca","has_results":false},{"nct_id":"NCT06583395","title":"Quest to Analyze One Thousand Humans Meditating","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":3000,"lead_sponsor_name":"Tobias Moeller-Bertram","has_results":false},{"nct_id":"NCT03471728","title":"Post-marketing Surveillance of Linaclotide Tablet in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation (Excluding Constipation Due to Organic Diseases)","phase":"","overall_status":"COMPLETED","enrollment_count":2475,"lead_sponsor_name":"Astellas Pharma Inc","has_results":false},{"nct_id":"NCT05795049","title":"Genetic Carbohydrate Maldigestion as a Model to Study Food Hypersensitivity","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Nottingham University Hospitals NHS Trust","has_results":false},{"nct_id":"NCT04031469","title":"A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease","phase":"","overall_status":"SUSPENDED","enrollment_count":1000,"lead_sponsor_name":"ProgenaBiome","has_results":false},{"nct_id":"NCT06117865","title":"Digital Treatment of Irritable Bowel Syndrome (IBS)","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":728,"lead_sponsor_name":"Haukeland University Hospital","has_results":false},{"nct_id":"NCT06072287","title":"The Living With a Long-Term Condition Study","phase":"","overall_status":"UNKNOWN","enrollment_count":600,"lead_sponsor_name":"King's College London","has_results":false},{"nct_id":"NCT01714843","title":"A Study to Evaluate the Effect of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":559,"lead_sponsor_name":"Astellas Pharma Inc","has_results":false},{"nct_id":"NCT03931785","title":"A Study of MD-7246 to Treat Abdominal Pain in Patients With Diarrhea-predominant Irritable Bowel Syndrome","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":515,"lead_sponsor_name":"Ironwood Pharmaceuticals, Inc.","has_results":true},{"nct_id":"NCT02316899","title":"Phase III Study to Evaluate the Efficacy and Safety of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":500,"lead_sponsor_name":"Astellas Pharma Inc","has_results":false},{"nct_id":"NCT07168434","title":"Saccharomyces Boulardii CNCM I-745 in Irritable Bowel Syndrome","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":406,"lead_sponsor_name":"Biocodex","has_results":false},{"nct_id":"NCT06676514","title":"Study to Evaluate the Treatment Benefits of Probiotic Clostridium Butyricum CBM588® for IBS-D","phase":"NA","overall_status":"COMPLETED","enrollment_count":405,"lead_sponsor_name":"Liaquat University of Medical & Health Sciences","has_results":false},{"nct_id":"NCT05230277","title":"OSTEOPATHY IN THE TREATMENT OF IBS SYMPTOMS IN ADULTS","phase":"NA","overall_status":"UNKNOWN","enrollment_count":404,"lead_sponsor_name":"Centre Hospitalier de Troyes","has_results":false},{"nct_id":"NCT06889779","title":"Study Evaluating the Efficacy of Different Mixes of HMO-2FL + Humiome® Post LB on IBS Gastrointestinal Symptoms","phase":"NA","overall_status":"RECRUITING","enrollment_count":402,"lead_sponsor_name":"dsm-firmenich Switzerland AG","has_results":false},{"nct_id":"NCT06960369","title":"Efficacy of Repeated Transcranial Magnetic Stimulation Combined With a Live Probiotic Tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live) in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":400,"lead_sponsor_name":"The First Affiliated Hospital of Soochow University","has_results":false},{"nct_id":"NCT03178877","title":"The Prevalence of Irritable Bowel Syndrome Using Rome IV Criteria in Medical Student and The Related Factors","phase":"","overall_status":"COMPLETED","enrollment_count":350,"lead_sponsor_name":"Indonesia University","has_results":false},{"nct_id":"NCT03482765","title":"A Study of Probiotics in IBS Subjects","phase":"NA","overall_status":"COMPLETED","enrollment_count":336,"lead_sponsor_name":"Vedic Lifesciences Pvt. Ltd.","has_results":false},{"nct_id":"NCT03550742","title":"Effect of HMOs as Nutritional Support for Normal Bowel Movements in IBS Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":317,"lead_sponsor_name":"Glycom, Inc.","has_results":false},{"nct_id":"NCT07471490","title":"Specimen and Data Collection for a Novel Biomarker Combination for the Differential Diagnosis of Inflammatory Bowel Disease and Irritable Bowel Syndrome.","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":300,"lead_sponsor_name":"DiaSorin Inc.","has_results":false},{"nct_id":"NCT03002584","title":"International Psychometric Validation Study of the Intestinal Gas Questionnaire (IGQ)","phase":"","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"University Paris 7 - Denis Diderot","has_results":false},{"nct_id":"NCT03449628","title":"L. Casei DG® in Patients With Irritable Bowel Syndrome.","phase":"NA","overall_status":"COMPLETED","enrollment_count":264,"lead_sponsor_name":"SOFAR S.p.A.","has_results":false},{"nct_id":"NCT06727422","title":"Efficacy of Rifaximin With NAC in IBS-D","phase":"PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":225,"lead_sponsor_name":"Mark Pimentel, MD","has_results":false},{"nct_id":"NCT06914921","title":"Enteric-Coated Peppermint Oil Versus Standard Antispasmodic in SLC6A4 (5-HTTLPR) Carriers With Irritable Bowel Syndrome.","phase":"NA","overall_status":"COMPLETED","enrollment_count":224,"lead_sponsor_name":"S.LAB (SOLOWAYS)","has_results":false},{"nct_id":"NCT06665867","title":"VICO-trial: Video Consultations in the Follow-up of Children With Functional Abdominal Pain Disorders","phase":"NA","overall_status":"RECRUITING","enrollment_count":208,"lead_sponsor_name":"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","has_results":false},{"nct_id":"NCT05205785","title":"Human Milk Oligosaccharides (HMOs) for Irritable Bowel Syndrome (IBS)","phase":"NA","overall_status":"TERMINATED","enrollment_count":204,"lead_sponsor_name":"dsm-firmenich Switzerland AG","has_results":false},{"nct_id":"NCT07425145","title":"Transcutaneous Electrical Acustimulation for IBS-D: A Multicenter Study","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":200,"lead_sponsor_name":"First People's Hospital of Foshan","has_results":false},{"nct_id":"NCT05192603","title":"Comparison Between Low FODMAP and SSRD in IBS","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":200,"lead_sponsor_name":"Region Skane","has_results":false},{"nct_id":"NCT07424898","title":"Lactose Intolerance and Intestinal Permability","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":200,"lead_sponsor_name":"Bezmialem Vakif University","has_results":false},{"nct_id":"NCT05815602","title":"Ebastine Versus Mebeverine in IBS Patients","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"Guy Boeckxstaens","has_results":false},{"nct_id":"NCT05643534","title":"Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":180,"lead_sponsor_name":"Ardelyx","has_results":false},{"nct_id":"NCT06426745","title":"Split-dose Versus Single-dose Bowel Preparation for Colonoscopy","phase":"NA","overall_status":"COMPLETED","enrollment_count":180,"lead_sponsor_name":"Egymedicalpedia","has_results":false},{"nct_id":"NCT07388589","title":"Soluble and Osmotic Fibre (SOLOS) Diet for Constipation","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":180,"lead_sponsor_name":"Singapore Institute of Technology","has_results":false},{"nct_id":"NCT06066866","title":"Microbiome Sampling in GI Disease With a Focus on Small Intestinal Microbial Assessment","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":150,"lead_sponsor_name":"Stanford University","has_results":false},{"nct_id":"NCT07534930","title":"Personalised Multidisciplinary Treatment in Moderate to Severe IBS","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":150,"lead_sponsor_name":"Linkoeping University","has_results":false},{"nct_id":"NCT05054309","title":"A Trial to Evaluate the Effects of Bifidobacterium Longum NCC3001 on Intestinal and Psychological Symptoms in Subjects With Irritable Bowel Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":146,"lead_sponsor_name":"Société des Produits Nestlé (SPN)","has_results":false},{"nct_id":"NCT04129762","title":"Effect of a Diet Without Non-caloric Sweeteners on Gastrointestinal Symptoms in Patients With IBS and Dyspepsia","phase":"NA","overall_status":"UNKNOWN","enrollment_count":140,"lead_sponsor_name":"Hospital General de Mexico","has_results":false},{"nct_id":"NCT05900752","title":"A Multi-Strain Probiotic Reduces the Frequency of Diarrhea in IBS-D Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":140,"lead_sponsor_name":"Shenzhen Precision Health Food Technology Co. Ltd.,","has_results":false},{"nct_id":"NCT05453084","title":"Exercise and Irritable Bowel Syndrome (IBS)","phase":"NA","overall_status":"COMPLETED","enrollment_count":137,"lead_sponsor_name":"Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis","has_results":false},{"nct_id":"NCT00421707","title":"Randomized Placebo Controlled Efficacy And Safety Study Investigating GW876008 In Patients With Irritable Bowel Syndrome","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":133,"lead_sponsor_name":"GlaxoSmithKline","has_results":true},{"nct_id":"NCT04060121","title":"Efficacy of Psychological Therapies in Patients With Functional Bowel Disorders","phase":"","overall_status":"COMPLETED","enrollment_count":126,"lead_sponsor_name":"Indiana University","has_results":false},{"nct_id":"NCT07125625","title":"Probiotic Mixture (L. Rhamnosus GG and L. Plantarum 299V) In Pediatric Irritable Bowel Syndrome","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":124,"lead_sponsor_name":"University of Bari","has_results":false},{"nct_id":"NCT07337343","title":"Co-Development and Validation of Colonic Symptom Pictograms for Young People","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":120,"lead_sponsor_name":"University of Auckland, New Zealand","has_results":false},{"nct_id":"NCT06993272","title":"Relaxation Music for Chronic Pain","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":120,"lead_sponsor_name":"University of California, Irvine","has_results":false},{"nct_id":"NCT03432078","title":"Individual vs. Group Hypnotherapy in Patients With Irritable Bowel Syndrome","phase":"NA","overall_status":"UNKNOWN","enrollment_count":119,"lead_sponsor_name":"Sahlgrenska University Hospital","has_results":false},{"nct_id":"NCT03306381","title":"The Effect of Dietary Intervention on Symptoms, Epigenetics, and Gut Microbiota in IBS","phase":"NA","overall_status":"COMPLETED","enrollment_count":105,"lead_sponsor_name":"Region Skane","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}