{"disease":{"id":"hypothalamic-obesity","name":"hypothalamic obesity"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06239116","title":"A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":150,"lead_sponsor_name":"Rhythm Pharmaceuticals, Inc.","has_results":false},{"nct_id":"NCT05774756","title":"A Trial of Setmelanotide in Acquired Hypothalamic Obesity","phase":"PHASE3","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":120,"lead_sponsor_name":"Rhythm Pharmaceuticals, Inc.","has_results":false},{"nct_id":"NCT06217848","title":"The Effect of GLP-1 Agonist in Patients With Hypothalamic Obesity: Prospective, Pilot Study","phase":"EARLY_PHASE1","overall_status":"UNKNOWN","enrollment_count":50,"lead_sponsor_name":"Seoul National University Hospital","has_results":false},{"nct_id":"NCT02860923","title":"Efficacy and Safety of Exenatide in the Treatment of Hypothalamic Obesity After Craniopharyngioma Therapy","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":42,"lead_sponsor_name":"University Hospital, Bordeaux","has_results":false},{"nct_id":"NCT05319301","title":"Identification and Clinical Relevance of an Oxytocin Deficient State (Melatonin Study)","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau","has_results":false},{"nct_id":"NCT06760546","title":"A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":39,"lead_sponsor_name":"Rhythm Pharmaceuticals, Inc.","has_results":false},{"nct_id":"NCT06046443","title":"A Study to Assess Efficacy and Safety of LB54640 in Patients With Hypothalamic Obesity","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":28,"lead_sponsor_name":"Rhythm Pharmaceuticals, Inc.","has_results":false},{"nct_id":"NCT07156578","title":"A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)","phase":"PHASE2","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":25,"lead_sponsor_name":"Rhythm Pharmaceuticals, Inc.","has_results":false},{"nct_id":"NCT06299891","title":"Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":24,"lead_sponsor_name":"Seattle Children's Hospital","has_results":false},{"nct_id":"NCT03845075","title":"48 Weeks, Study to Evaluate Overall Safety and Tolerability of Co-administration of Tesofensine and Metoprolol in Subjects With Hypothalamic Injury-induced Obesity (HIO)","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":21,"lead_sponsor_name":"Saniona","has_results":true},{"nct_id":"NCT04725240","title":"Open-Label Study of Setmelanotide in Hypothalamic Obesity","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":18,"lead_sponsor_name":"Rhythm Pharmaceuticals, Inc.","has_results":true},{"nct_id":"NCT03673813","title":"A Personalized Program of Physical Activity and Diet for Hypothalamic Obesity","phase":"","overall_status":"COMPLETED","enrollment_count":16,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT03708913","title":"Neuromodulation for Hypothalamic Obesity","phase":"NA","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"University of British Columbia","has_results":false},{"nct_id":"NCT05147415","title":"Study of Tesomet With Open-label Extension in Subjects With Hypothalamic Obesity (HO)","phase":"PHASE2","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"Saniona","has_results":false}],"total":14},"guidelines":[],"source":"Drug Landscape verified database"}