{"disease":{"id":"hypercapnia","name":"hypercapnia"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06298435","title":"Optimising Ventilatory Strategies by Using Positive Respiratory Integer Measurements","phase":"","overall_status":"UNKNOWN","enrollment_count":20000,"lead_sponsor_name":"University Medical Center Groningen","has_results":false},{"nct_id":"NCT04304339","title":"Hypercapnic Acute Respiratory Failure in the ICU : the YETI Study","phase":"","overall_status":"COMPLETED","enrollment_count":862,"lead_sponsor_name":"French Society for Intensive Care","has_results":false},{"nct_id":"NCT07211529","title":"Intraoperative Paravertebral Block and Postoperative Complications","phase":"NA","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Tongji Hospital","has_results":false},{"nct_id":"NCT06970041","title":"To Assess the Types of Mechanical Ventilation in Enabling Therapeutic Bronchofiberoscopy in Patients With Decompensated Respiratory Acidosis (Complete Respiratory Failure).","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":315,"lead_sponsor_name":"Medical University of Silesia","has_results":false},{"nct_id":"NCT04409470","title":"Venous Versus Arterial Blood Gas Sampling in Undifferentiated Emergency Patients","phase":"","overall_status":"COMPLETED","enrollment_count":250,"lead_sponsor_name":"University Hospital, Linkoeping","has_results":false},{"nct_id":"NCT04793178","title":"The Effectivity of End-tidal CO2 and Oxygen Reserve Index (ORI) Monitoring in Sedation","phase":"NA","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Yuksek Ihtisas Hospital","has_results":false},{"nct_id":"NCT04980820","title":"Changes in Capillary Carbon Dioxide Partial Pressure (pCO2) While Wearing FFP2 / FFP3 Masks","phase":"NA","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Medical University of Vienna","has_results":false},{"nct_id":"NCT06988111","title":"Management of Post-operative Respiratory Failure by Using NIV and High Velocity Nasal Insufflation (HVNI)","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":180,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT06114667","title":"Nasal High Flow Versus Non-invasive Ventilation for Early Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Hypercapnic Acidosis","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":174,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT03741998","title":"Nasopharyngeal Airway Facilitate Transnasal Humidified Rapid Insufflation Ventilatory Exchange","phase":"NA","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"RenJi Hospital","has_results":false},{"nct_id":"NCT06918288","title":"Post-extubation Nasal Humidified High-flow Oxygen Versus Non-invasive Positive Pressure Ventilation","phase":"PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":100,"lead_sponsor_name":"Benha University","has_results":false},{"nct_id":"NCT05972304","title":"Efficiency and Safety of Nasal Positive Airway Pressure Systems During Endoscopy","phase":"NA","overall_status":"COMPLETED","enrollment_count":98,"lead_sponsor_name":"University of Ulm","has_results":false},{"nct_id":"NCT07065656","title":"HVNI vs NIPPV in Type 2 Respiratory Failure","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":84,"lead_sponsor_name":"National University Hospital, Singapore","has_results":false},{"nct_id":"NCT05793437","title":"Effects of Permissive Hypercapnia on Concentration of Postoperative Plasma Neurofilament Light","phase":"NA","overall_status":"COMPLETED","enrollment_count":84,"lead_sponsor_name":"Affiliated Hospital of Jiaxing University","has_results":false},{"nct_id":"NCT05761756","title":"Oxygen Toxicity: Mechanisms in Humans","phase":"NA","overall_status":"RECRUITING","enrollment_count":62,"lead_sponsor_name":"Duke University","has_results":false},{"nct_id":"NCT06158282","title":"Effects of Walking Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":60,"lead_sponsor_name":"Centro Universitario La Salle","has_results":false},{"nct_id":"NCT05188651","title":"Effect of FFP2 Masks on Peripheral Oxygen Saturation and Pulse Rate During the COVID-19 Pandemic","phase":"","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Catholic University of the Sacred Heart","has_results":false},{"nct_id":"NCT06638528","title":"Effects of Walking Apnea At High Lung Volume on Hypoalgesia","phase":"NA","overall_status":"RECRUITING","enrollment_count":60,"lead_sponsor_name":"Universidad Rey Juan Carlos","has_results":false},{"nct_id":"NCT06638515","title":"Effects of Walking Apnea At Low Lung Volume on Hypoalgesia","phase":"NA","overall_status":"RECRUITING","enrollment_count":60,"lead_sponsor_name":"Universidad Rey Juan Carlos","has_results":false},{"nct_id":"NCT06158295","title":"Effects of Walking Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":60,"lead_sponsor_name":"Centro Universitario La Salle","has_results":false},{"nct_id":"NCT06150677","title":"Effects of Static Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":60,"lead_sponsor_name":"Centro Universitario La Salle","has_results":false},{"nct_id":"NCT06158256","title":"Effects of Static Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":60,"lead_sponsor_name":"Centro Universitario La Salle","has_results":false},{"nct_id":"NCT04615078","title":"Study Evaluating Telemonitoring and Experimentation in Telemedicine for the Improvement of Healthcare Pathways (ETAPES Program) Compared to Standard of Care in Patients With Chronic Respiratory Failure Receiving Non-invasive Home Ventilation","phase":"NA","overall_status":"COMPLETED","enrollment_count":56,"lead_sponsor_name":"Air Liquide Santé International","has_results":false},{"nct_id":"NCT04310579","title":"Clinical Study to Investigate the Effect of the Combination of Psychotropic Drugs and an Opioid on Ventilation","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":55,"lead_sponsor_name":"Food and Drug Administration (FDA)","has_results":true},{"nct_id":"NCT06286306","title":"Pronostic Value of Fluid Responsiveness Evaluated by Inferior Vena Cava Collapsibility Index in Patients Admitted in ICU With Acute Respiratory Failure","phase":"","overall_status":"UNKNOWN","enrollment_count":50,"lead_sponsor_name":"University Hospital, Lille","has_results":false},{"nct_id":"NCT05829083","title":"DUET Versus Standard Interface for Hypercapnic COPD Patients","phase":"NA","overall_status":"RECRUITING","enrollment_count":50,"lead_sponsor_name":"Larissa University Hospital","has_results":false},{"nct_id":"NCT04258774","title":"The Effect of Respiratory Challenge on the BOLD Signal","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":48,"lead_sponsor_name":"Washington University School of Medicine","has_results":false},{"nct_id":"NCT06132490","title":"Intra-abdominal Pressure and Insufflator Effects in Robotic Surgery","phase":"NA","overall_status":"COMPLETED","enrollment_count":43,"lead_sponsor_name":"Koç University","has_results":false},{"nct_id":"NCT06944093","title":"Listen to a Audio Book","phase":"NA","overall_status":"COMPLETED","enrollment_count":42,"lead_sponsor_name":"Ataturk University","has_results":false},{"nct_id":"NCT04926805","title":"Physiological Study to Compare Noninvasive Ventilation (NIV) Masks","phase":"NA","overall_status":"TERMINATED","enrollment_count":40,"lead_sponsor_name":"Fisher and Paykel Healthcare","has_results":false},{"nct_id":"NCT07198880","title":"Impact of Home Non Invasive Ventilation in Patients With Chronic Obstructive Pulmonary Disease Discharged From Assiut University Hospital","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":40,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT04962568","title":"Ultrasonographic Evaluation of the Diaphragm During NHF Versus NIV Use in Respiratory Failure","phase":"NA","overall_status":"UNKNOWN","enrollment_count":35,"lead_sponsor_name":"Jens Bräunlich","has_results":false},{"nct_id":"NCT06437301","title":"End Tidal CO2 and Masks: Is There a Correlation?","phase":"NA","overall_status":"COMPLETED","enrollment_count":31,"lead_sponsor_name":"CHRISTUS Health","has_results":false},{"nct_id":"NCT04041531","title":"Triple H ODC Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Medical University Innsbruck","has_results":false},{"nct_id":"NCT05948527","title":"Safety and Efficacy of High Flow Nasal Canula in Patients With Mild Hypercapnia","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Mansoura University","has_results":false},{"nct_id":"NCT03221387","title":"Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Temple University","has_results":true},{"nct_id":"NCT05536076","title":"Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury","phase":"NA","overall_status":"RECRUITING","enrollment_count":30,"lead_sponsor_name":"VA Office of Research and Development","has_results":false},{"nct_id":"NCT03561974","title":"Impact of Humidification on Sleep Quality During Home Non Invasive Ventilation","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"ADIR Association","has_results":false},{"nct_id":"NCT06636825","title":"Influence of Caffeine on Psychomotor Vigilance and Carbon Dioxide Tolerance During Graded Hypercapnia","phase":"NA","overall_status":"COMPLETED","enrollment_count":29,"lead_sponsor_name":"United States Army Research Institute of Environmental Medicine","has_results":false},{"nct_id":"NCT04871893","title":"Safety and Efficacy Evaluation of CO2 Removal in Combination With Continuous Veno-Venous Hemodialysis/Hemodiafiltration Therapy","phase":"NA","overall_status":"COMPLETED","enrollment_count":28,"lead_sponsor_name":"Fresenius Medical Care Deutschland GmbH","has_results":false},{"nct_id":"NCT05470465","title":"Effect of Selective Serotonin Reuptake Inhibitors (SSRIs) and an Opioid on Ventilation","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":27,"lead_sponsor_name":"Food and Drug Administration (FDA)","has_results":true},{"nct_id":"NCT04512781","title":"Clinical Efficacy in Relief of Dyspnea by HVNI: Evaluation of New Cannulae Designs","phase":"NA","overall_status":"COMPLETED","enrollment_count":26,"lead_sponsor_name":"Vapotherm, Inc.","has_results":true},{"nct_id":"NCT05189158","title":"Ventilatory Responses to Hypercapnic and Hypoxic Conditions in Hyperventilants","phase":"NA","overall_status":"COMPLETED","enrollment_count":24,"lead_sponsor_name":"Centre Hospitalier Universitaire Saint Pierre","has_results":false},{"nct_id":"NCT04771663","title":"Variability of SpO2 Measurements Depending on the Choice of Finger for Sensor Placement","phase":"NA","overall_status":"COMPLETED","enrollment_count":24,"lead_sponsor_name":"Czech Technical University in Prague","has_results":false},{"nct_id":"NCT04780724","title":"Evaluation of SpO2 Measurement Using a Smartwatch","phase":"NA","overall_status":"COMPLETED","enrollment_count":24,"lead_sponsor_name":"Czech Technical University in Prague","has_results":false},{"nct_id":"NCT05505279","title":"Ventilatory Effects of THRIVE During EBUS","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":20,"lead_sponsor_name":"Rijnstate Hospital","has_results":false},{"nct_id":"NCT05441007","title":"The Effect of Hypercapnia on Physiological Parameters During Short-term Breathing","phase":"NA","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"Czech Technical University in Prague","has_results":false},{"nct_id":"NCT03095300","title":"Prone Positioning During High Flow Oxygen Therapy in Acute Hypoxemic Respiratory Failure","phase":"NA","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"Catholic University of the Sacred Heart","has_results":false},{"nct_id":"NCT05116397","title":"Influence of Graded Hypercapnia on Endurance Exercise Performance","phase":"NA","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"United States Army Research Institute of Environmental Medicine","has_results":false},{"nct_id":"NCT03444428","title":"The Relationship Between Arterial Stiffness and Respiratory Failure in Motor Neurone Disease","phase":"","overall_status":"COMPLETED","enrollment_count":13,"lead_sponsor_name":"Guy's and St Thomas' NHS Foundation Trust","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}