{"disease":{"id":"hepatocellular-cancer","name":"hepatocellular cancer"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03517332","title":"Circulating Tumor DNA Exposure in Peripheral Blood","phase":"","overall_status":"UNKNOWN","enrollment_count":10000,"lead_sponsor_name":"Quantgene Inc.","has_results":false},{"nct_id":"NCT06084234","title":"National Liver Cancer Screening Trial","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":5500,"lead_sponsor_name":"University of Texas Southwestern Medical Center","has_results":false},{"nct_id":"NCT07010198","title":"Head-to-Head Comparison of Hepatocellular Cancer (HCC) Screening Strategies: A Prospective Population-Based Cohort Study in Zhongshan City","phase":"","overall_status":"RECRUITING","enrollment_count":4500,"lead_sponsor_name":"Zhongshan People's Hospital, Guangdong, China","has_results":false},{"nct_id":"NCT05176483","title":"Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":1314,"lead_sponsor_name":"Exelixis","has_results":false},{"nct_id":"NCT07224750","title":"A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"City of Hope Medical Center","has_results":false},{"nct_id":"NCT03896958","title":"The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)","phase":"","overall_status":"UNKNOWN","enrollment_count":1000,"lead_sponsor_name":"SpeciCare","has_results":false},{"nct_id":"NCT04637048","title":"Observational Study on Patients With Hepatobiliary Tumors","phase":"","overall_status":"UNKNOWN","enrollment_count":1000,"lead_sponsor_name":"Gang Chen, MD","has_results":false},{"nct_id":"NCT05095714","title":"FAST-IRM for HCC suRveillance in pAtients With High risK of Liver Cancer.","phase":"NA","overall_status":"RECRUITING","enrollment_count":944,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT03170960","title":"Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors","phase":"PHASE1","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":914,"lead_sponsor_name":"Exelixis","has_results":false},{"nct_id":"NCT07223424","title":"Patient Preference for Subcutaneous vs. Intravenous Immune Therapy","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":880,"lead_sponsor_name":"Diwakar Davar","has_results":false},{"nct_id":"NCT05038254","title":"Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":750,"lead_sponsor_name":"M.D. Anderson Cancer Center","has_results":false},{"nct_id":"NCT03475953","title":"A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors","phase":"PHASE1, PHASE2","overall_status":"UNKNOWN","enrollment_count":747,"lead_sponsor_name":"Institut Bergonié","has_results":false},{"nct_id":"NCT07141056","title":"The Impact of Emotional Stress on Immunotherapy Outcomes in Liver Cancer Patients: A Multi-Cohort Study","phase":"","overall_status":"RECRUITING","enrollment_count":700,"lead_sponsor_name":"Guilin Medical University, China","has_results":false},{"nct_id":"NCT06641713","title":"HAIC Compared With TACE in Huge Hepatocellular Carcinoma","phase":"","overall_status":"RECRUITING","enrollment_count":664,"lead_sponsor_name":"Sun Yat-sen University","has_results":false},{"nct_id":"NCT05078047","title":"Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":646,"lead_sponsor_name":"UNICANCER","has_results":false},{"nct_id":"NCT02838836","title":"Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers","phase":"","overall_status":"RECRUITING","enrollment_count":620,"lead_sponsor_name":"University of Missouri-Columbia","has_results":false},{"nct_id":"NCT05714124","title":"Liver Embolization Approaches for Tumor Management","phase":"","overall_status":"RECRUITING","enrollment_count":580,"lead_sponsor_name":"IRCCS San Raffaele","has_results":false},{"nct_id":"NCT05489250","title":"The PLATON Network","phase":"","overall_status":"TERMINATED","enrollment_count":565,"lead_sponsor_name":"Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest","has_results":false},{"nct_id":"NCT07321613","title":"Effect of TCC Cocktail Combined With TACE Versus TACE Alone on Survival in uHCC Patients","phase":"","overall_status":"COMPLETED","enrollment_count":545,"lead_sponsor_name":"Shanghai Zhongshan Hospital","has_results":false},{"nct_id":"NCT03383458","title":"A Study of Nivolumab in Participants With Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative Hepatic Resection or Ablation","phase":"PHASE3","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":545,"lead_sponsor_name":"Bristol-Myers Squibb","has_results":false},{"nct_id":"NCT03405909","title":"Standardized CEUS Algorithms for Diagnosis of HCC - Prospective German Multicenter Study","phase":"","overall_status":"COMPLETED","enrollment_count":517,"lead_sponsor_name":"University Hospital Erlangen","has_results":false},{"nct_id":"NCT01631552","title":"Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":515,"lead_sponsor_name":"Gilead Sciences","has_results":true},{"nct_id":"NCT06644430","title":"Ablation of Pulmonary Oligometastasis Combined With System for Advanced Hepatocellular Carcinoma","phase":"","overall_status":"RECRUITING","enrollment_count":470,"lead_sponsor_name":"Sun Yat-sen University","has_results":false},{"nct_id":"NCT04445532","title":"Hepatobiliary Tumors Tissue Samples Acquisition","phase":"","overall_status":"UNKNOWN","enrollment_count":450,"lead_sponsor_name":"Peking Union Medical College Hospital","has_results":false},{"nct_id":"NCT02178722","title":"Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancers","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":444,"lead_sponsor_name":"Incyte Corporation","has_results":true},{"nct_id":"NCT05429866","title":"Immunological Variables Associated to ICI Toxicity in Cancer Patients","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":441,"lead_sponsor_name":"Jules Bordet Institute","has_results":false},{"nct_id":"NCT04576572","title":"Comparison of Criteria for Liver Transplantation in Hepatocellular Carcinoma","phase":"","overall_status":"COMPLETED","enrollment_count":424,"lead_sponsor_name":"Inonu University","has_results":false},{"nct_id":"NCT03787056","title":"Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer Patients","phase":"NA","overall_status":"RECRUITING","enrollment_count":410,"lead_sponsor_name":"Hospices Civils de Lyon","has_results":false},{"nct_id":"NCT06778317","title":"MSEPT9 Biomarker for Predicting Hepatocellular Carcinoma Occurrence in Patients with Cirrhosis","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":400,"lead_sponsor_name":"Central Hospital, Nancy, France","has_results":false},{"nct_id":"NCT06342414","title":"An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer","phase":"","overall_status":"RECRUITING","enrollment_count":400,"lead_sponsor_name":"City of Hope Medical Center","has_results":false},{"nct_id":"NCT04484636","title":"PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study)","phase":"NA","overall_status":"COMPLETED","enrollment_count":400,"lead_sponsor_name":"Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest","has_results":false},{"nct_id":"NCT06427941","title":"A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":392,"lead_sponsor_name":"BeOne Medicines","has_results":false},{"nct_id":"NCT05342350","title":"International Study of High-Risk Patients for Hepatocellular Carcinoma Using Liquid Biopsy","phase":"","overall_status":"TERMINATED","enrollment_count":360,"lead_sponsor_name":"Johns Hopkins University","has_results":false},{"nct_id":"NCT06422403","title":"A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":360,"lead_sponsor_name":"National University Hospital, Singapore","has_results":false},{"nct_id":"NCT05824975","title":"A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":358,"lead_sponsor_name":"GI Innovation, Inc.","has_results":false},{"nct_id":"NCT07070518","title":"Study of GV20-0251 in Participants With Solid Tumor Malignancies","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":350,"lead_sponsor_name":"GV20 Therapeutics","has_results":false},{"nct_id":"NCT06898398","title":"TACE Combined Surgery for the Resectable Huge HCC","phase":"","overall_status":"RECRUITING","enrollment_count":326,"lead_sponsor_name":"Sun Yat-sen University","has_results":false},{"nct_id":"NCT06503146","title":"18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":320,"lead_sponsor_name":"National Cancer Institute (NCI)","has_results":false},{"nct_id":"NCT03551951","title":"Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow","phase":"","overall_status":"RECRUITING","enrollment_count":320,"lead_sponsor_name":"University of Missouri-Columbia","has_results":false},{"nct_id":"NCT07101237","title":"An Exploratory Study on Developing an Integrated Approach Combining Multimodal Imaging and Multi-omics Characterization of Tumor Heterogeneity for Precision Diagnosis and Treatment Optimization in Liver Cancer.","phase":"","overall_status":"RECRUITING","enrollment_count":308,"lead_sponsor_name":"Peking Union Medical College Hospital","has_results":false},{"nct_id":"NCT07001085","title":"ctDNA Monitoring in Patients With HCC and mCRC","phase":"NA","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Medical University of Warsaw","has_results":false},{"nct_id":"NCT05775159","title":"Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":294,"lead_sponsor_name":"AstraZeneca","has_results":false},{"nct_id":"NCT02072356","title":"Radiolabeled Glass Beads in Treating Patients With Liver Cancer That Cannot be Removed by Surgery","phase":"EARLY_PHASE1","overall_status":"COMPLETED","enrollment_count":290,"lead_sponsor_name":"Ohio State University Comprehensive Cancer Center","has_results":false},{"nct_id":"NCT05540925","title":"Vascular Invasion Signatures in cfDNA Support Re-staging of Liver Cancer","phase":"","overall_status":"COMPLETED","enrollment_count":286,"lead_sponsor_name":"Eastern Hepatobiliary Surgery Hospital","has_results":false},{"nct_id":"NCT05444478","title":"Microwave Ablation Simultaneously Combined With Lenavatinib for Recurrent Hepatocellular Carcinoma","phase":"NA","overall_status":"RECRUITING","enrollment_count":274,"lead_sponsor_name":"Sun Yat-sen University","has_results":false},{"nct_id":"NCT04567615","title":"A Study of Relatlimab in Combination With Nivolumab in Participants With Advanced Liver Cancer Who Have Never Been Treated With Immuno-oncology Therapy After Prior Treatment With Tyrosine Kinase Inhibitors","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":266,"lead_sponsor_name":"Bristol-Myers Squibb","has_results":true},{"nct_id":"NCT05100082","title":"Survey of Cabozantinib Tablets Used To Treat People With Hepatocellular Carcinoma","phase":"","overall_status":"COMPLETED","enrollment_count":263,"lead_sponsor_name":"Takeda","has_results":false},{"nct_id":"NCT05620134","title":"Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer","phase":"PHASE1, PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":263,"lead_sponsor_name":"Salubris Biotherapeutics Inc","has_results":false},{"nct_id":"NCT01010126","title":"Temsirolimus and Bevacizumab in Treating Patients With Advanced Endometrial, Ovarian, Liver, Carcinoid, or Islet Cell Cancer","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":252,"lead_sponsor_name":"National Cancer Institute (NCI)","has_results":true},{"nct_id":"NCT05665348","title":"Study Evaluating the Benefit of Adding Ipilimumab to the Combination of Atezolizumab and Bevacizumab in Patients With Hepatocellular Carcinoma Receiving First-line Systemic Therapy","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":229,"lead_sponsor_name":"Federation Francophone de Cancerologie Digestive","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}