{"disease":{"id":"heart-failure-systolic","name":"heart failure systolic"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04743063","title":"Prospective Monitoring of Angiotensin Receptor Neprilysin Inhibitor in Older Adults With Heart Failure and Frailty","phase":"","overall_status":"UNKNOWN","enrollment_count":40000,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false},{"nct_id":"NCT06324682","title":"ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","phase":"","overall_status":"RECRUITING","enrollment_count":8400,"lead_sponsor_name":"University Hospital of Ferrara","has_results":false},{"nct_id":"NCT07332520","title":"Predicting Heart Failure Outcomes With Biomarkers and Imaging","phase":"","overall_status":"COMPLETED","enrollment_count":4000,"lead_sponsor_name":"Xinjiang Medical University","has_results":false},{"nct_id":"NCT05140642","title":"Safety and Efficacy Study of AI LVEF","phase":"NA","overall_status":"COMPLETED","enrollment_count":3495,"lead_sponsor_name":"Cedars-Sinai Medical Center","has_results":false},{"nct_id":"NCT03387813","title":"Hemodynamic-GUIDEd Management of Heart Failure","phase":"NA","overall_status":"COMPLETED","enrollment_count":2358,"lead_sponsor_name":"Abbott Medical Devices","has_results":true},{"nct_id":"NCT06811519","title":"AI-based Prediction of Cardiac Function Using Echocardiography and Body Composition Data (ECHO-FIT Study)","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Yonsei University","has_results":false},{"nct_id":"NCT05647577","title":"The Relationship Between Inflammatory ARTritis and CArdiac DIseAse","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":1285,"lead_sponsor_name":"University Hospital, Gentofte, Copenhagen","has_results":false},{"nct_id":"NCT04950218","title":"Prevalence and Risk Factors asSOciated With CArdiac comorbiDIty in psoriAsis","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Herlev and Gentofte Hospital","has_results":false},{"nct_id":"NCT03086746","title":"VItamin D as a Novel Determinant of Injurious Cardiac Remodelling After acuTE Myocardial Infarction","phase":"","overall_status":"UNKNOWN","enrollment_count":800,"lead_sponsor_name":"University of Leeds","has_results":false},{"nct_id":"NCT03374891","title":"A Multicenter Trial of a Shared DECision Support Intervention for Patients Offered Implantable Cardioverter-DEfibrillators","phase":"NA","overall_status":"COMPLETED","enrollment_count":790,"lead_sponsor_name":"University of Colorado, Denver","has_results":true},{"nct_id":"NCT04249648","title":"Hyperkalaemia and Its Impact on Therapy with RAASi","phase":"","overall_status":"COMPLETED","enrollment_count":651,"lead_sponsor_name":"Portsmouth Hospitals NHS Trust","has_results":false},{"nct_id":"NCT03425422","title":"ANTHEM-HFrEF Pivotal Study","phase":"NA","overall_status":"TERMINATED","enrollment_count":533,"lead_sponsor_name":"LivaNova","has_results":false},{"nct_id":"NCT05933083","title":"MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation","phase":"NA","overall_status":"RECRUITING","enrollment_count":516,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT03157219","title":"Manipal Heart Failure Registry (MHFR)","phase":"","overall_status":"UNKNOWN","enrollment_count":500,"lead_sponsor_name":"Manipal University","has_results":false},{"nct_id":"NCT06675552","title":"Non-interventional Study on Guideline Directed Medical Therapy for Patients With Heart Failure (HF) in Germany","phase":"","overall_status":"RECRUITING","enrollment_count":438,"lead_sponsor_name":"AstraZeneca","has_results":false},{"nct_id":"NCT03573869","title":"Atrial FIbrillation Treatment With Cryoballoon in Heart failurE (AFICHE)","phase":"NA","overall_status":"UNKNOWN","enrollment_count":404,"lead_sponsor_name":"G.Gennimatas General Hospital","has_results":false},{"nct_id":"NCT03387163","title":"Patient Reported Outcomes inVestigation Following Initiation of Drug Therapy With Entresto (Sacubitril/Valsartan) in Heart Failure","phase":"","overall_status":"COMPLETED","enrollment_count":402,"lead_sponsor_name":"Novartis Pharmaceuticals","has_results":false},{"nct_id":"NCT04201015","title":"Optimising Pacing for Contractility 2","phase":"PHASE2, PHASE3","overall_status":"RECRUITING","enrollment_count":400,"lead_sponsor_name":"University of Leeds","has_results":false},{"nct_id":"NCT05410990","title":"Eosinophil Indices in Patients With Acute Heart Failure","phase":"","overall_status":"COMPLETED","enrollment_count":395,"lead_sponsor_name":"Giresun University","has_results":false},{"nct_id":"NCT05714085","title":"Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)","phase":"PHASE2, PHASE3","overall_status":"RECRUITING","enrollment_count":342,"lead_sponsor_name":"Merck Sharp & Dohme LLC","has_results":false},{"nct_id":"NCT03030235","title":"Dapagliflozin in PRESERVED Ejection Fraction Heart Failure","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":324,"lead_sponsor_name":"Saint Luke's Health System","has_results":true},{"nct_id":"NCT07199088","title":"Comparative Efficacy and Safety of Acetazolamide Versus Metolazone as an Adjunct to Standard Therapy in Patients With Acute Decompensated Heart Failure","phase":"NA","overall_status":"RECRUITING","enrollment_count":320,"lead_sponsor_name":"University of Health Sciences Lahore","has_results":false},{"nct_id":"NCT02653482","title":"Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":263,"lead_sponsor_name":"Saint Luke's Health System","has_results":true},{"nct_id":"NCT05702970","title":"Beneficial Effects of Vitamin D Combined With Oral Iron Supplementation in Patients With Chronic Heart Failure and Iron Deficiency","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":258,"lead_sponsor_name":"University of Padova","has_results":false},{"nct_id":"NCT05989945","title":"HIDRAdenitis Suppurativa and HEART Disease","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":250,"lead_sponsor_name":"Herlev and Gentofte Hospital","has_results":false},{"nct_id":"NCT05726565","title":"Impact of Cardiac Rehabilitation on Acute Heart Failure Patients With Cognitive Impairment","phase":"","overall_status":"COMPLETED","enrollment_count":247,"lead_sponsor_name":"Chang Gung Memorial Hospital","has_results":false},{"nct_id":"NCT05802563","title":"Machine Learning Enabled Time Series Analysis in Medicine","phase":"","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"HagaZiekenhuis","has_results":false},{"nct_id":"NCT04325867","title":"Integrated Distance Management Strategy for Patients With Cardiovascular Diseases in the Context of COVID-19","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Professor Adrian Covic","has_results":false},{"nct_id":"NCT03755570","title":"How is COGNItive Function Affected by Cardiac Resynchronisation Therapy?","phase":"","overall_status":"SUSPENDED","enrollment_count":198,"lead_sponsor_name":"Royal Cornwall Hospitals Trust","has_results":false},{"nct_id":"NCT03398369","title":"Mechanistic Clinical Trial of Advanced Imaging for CRT","phase":"NA","overall_status":"UNKNOWN","enrollment_count":180,"lead_sponsor_name":"University of Virginia","has_results":false},{"nct_id":"NCT05928026","title":"Financial Support in an Underserved and Low-Income Population With Heart Failure","phase":"NA","overall_status":"COMPLETED","enrollment_count":153,"lead_sponsor_name":"University of Texas Southwestern Medical Center","has_results":false},{"nct_id":"NCT06478901","title":"Precision of AI-Based Cardiac Ultrasound for LVEF in the Elderly","phase":"","overall_status":"COMPLETED","enrollment_count":129,"lead_sponsor_name":"Hôpital Broca APHP","has_results":false},{"nct_id":"NCT02963272","title":"ST2 for the Management of Heart Failure - STADE-HF","phase":"NA","overall_status":"COMPLETED","enrollment_count":123,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT05387967","title":"Safety and Tolerability of Sacubitril/Valsartan in Heart Failure Patient With Reduced Ejection Fraction","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":121,"lead_sponsor_name":"National Institute of Cardiovascular Diseases, Pakistan","has_results":false},{"nct_id":"NCT04083690","title":"Multi-lead ECG to Effectively Optimize Resynchronization Devices: New CRT Recipients","phase":"NA","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"Allina Health System","has_results":false},{"nct_id":"NCT02797340","title":"Metformin Pharmacokinetics in Patients With Chronic and Acute Heart Failure","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":110,"lead_sponsor_name":"Aarhus University Hospital","has_results":false},{"nct_id":"NCT06084468","title":"Cardiac Structure and Function in Patients with Cystic Fibrosis","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":104,"lead_sponsor_name":"Herlev and Gentofte Hospital","has_results":false},{"nct_id":"NCT03797001","title":"Interleukin-1 Blockade In Recently Decompensated Heart Failure - 2","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":102,"lead_sponsor_name":"Virginia Commonwealth University","has_results":true},{"nct_id":"NCT06240403","title":"Digoxin and Senolysis in Heart Failure and Diabetes Mellitus","phase":"PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":100,"lead_sponsor_name":"University of Leeds","has_results":false},{"nct_id":"NCT04112576","title":"Physiological Signals, Activity and Posture for Surface Mounted Insertable Cardiac Monitor in Heart Failure Study","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"Boston Scientific Corporation","has_results":false},{"nct_id":"NCT03349593","title":"Prevalence of Hypovolemia and Heart Failure in Non-cardiac Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"Umeå University","has_results":false},{"nct_id":"NCT04570865","title":"Dapagliflozin And Pulmonary Artery Hemodynamics in Heart Failure With Reduced Ejection Fraction Patients With CardioMEMS®","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Scripps Health","has_results":false},{"nct_id":"NCT06434025","title":"IV Iron and SGLT2 Inhibitor on Ventricular Function and Myocardial Iron Content in Heart Failure With Iron Deficiency","phase":"PHASE3","overall_status":"NOT_YET_RECRUITING","enrollment_count":99,"lead_sponsor_name":"Hospital de Clinicas de Porto Alegre","has_results":false},{"nct_id":"NCT04064541","title":"Virtual Visits to Optimize Research Trial Offerings to HF Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":94,"lead_sponsor_name":"The Cleveland Clinic","has_results":false},{"nct_id":"NCT03627585","title":"Reprogramming to Prevent Progressive Pacemaker-induced Remodelling","phase":"NA","overall_status":"COMPLETED","enrollment_count":91,"lead_sponsor_name":"University of Leeds","has_results":false},{"nct_id":"NCT06336746","title":"Cardiac Performance During Steep Trendelenburg Position in Patients Undergoing Robotic Surgery Surgery.","phase":"","overall_status":"RECRUITING","enrollment_count":80,"lead_sponsor_name":"Karlstad Central Hospital","has_results":false},{"nct_id":"NCT04611594","title":"Fluid Restriction in Patients With Heart Failure","phase":"NA","overall_status":"UNKNOWN","enrollment_count":75,"lead_sponsor_name":"Hospital de Clinicas de Porto Alegre","has_results":false},{"nct_id":"NCT03351283","title":"Effect of Sodium Intake on Brain Natriuretic Peptide Levels in Patients With Heart Failure","phase":"NA","overall_status":"COMPLETED","enrollment_count":70,"lead_sponsor_name":"Instituto Mexicano del Seguro Social","has_results":false},{"nct_id":"NCT04705337","title":"Levosimendan In Ambulatory Heart Failure Patients","phase":"PHASE4","overall_status":"TERMINATED","enrollment_count":70,"lead_sponsor_name":"Medical University of Bialystok","has_results":false},{"nct_id":"NCT06501313","title":"PhotobiomoduLation for pAtientS With Advanced hEart failuRe","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":70,"lead_sponsor_name":"Semmelweis University Heart and Vascular Center","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}