{"disease":{"id":"heart-disease-chronic","name":"heart disease chronic"},"drugs":{"marketed":[{"drug_id":"prevnar-family","indication_name":"Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F in adults 18 years of age and older with chronic heart disease, chronic lung disease, diabetes mellitus, or functional or anatomical asplenia","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Prevnar family","generic_name":"prevnar-family","company_name":"Pfizer Inc.","drug_phase":"marketed","molecular_target":"Streptococcus pneumoniae","drug_class":"Vaccine","quality_score":45,"revenue":"6494","mechanism":"Induces an immune response to Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F"},{"drug_id":"mpnc-candidate","indication_name":"Prevention of invasive pneumococcal disease (IPD) caused by Streptococcus pneumoniae in adults 18 years of age and older with chronic heart disease, chronic lung disease, diabetes mellitus, or alcoholism","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"mPnC candidate","generic_name":"mpnc-candidate","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"Specific protein or receptor involved in disease pathology","drug_class":"Novel therapeutic agent","quality_score":50,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":2,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03847753","title":"Exploring the Comorbidity Between Mental Disorders and General Medical Conditions","phase":"","overall_status":"COMPLETED","enrollment_count":5940299,"lead_sponsor_name":"University of Aarhus","has_results":false},{"nct_id":"NCT05813652","title":"Relative Impacts on Preventative Primary Care--a Longitudinal Evaluation of COVID-19:Phase 1","phase":"","overall_status":"COMPLETED","enrollment_count":919928,"lead_sponsor_name":"McMaster University","has_results":false},{"nct_id":"NCT03987633","title":"EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality","phase":"","overall_status":"RECRUITING","enrollment_count":200000,"lead_sponsor_name":"Future Genetics Limited","has_results":false},{"nct_id":"NCT02612688","title":"Pragmatic Trial of Video Education in Nursing Homes","phase":"NA","overall_status":"COMPLETED","enrollment_count":197692,"lead_sponsor_name":"Brown University","has_results":true},{"nct_id":"NCT03840928","title":"PatientSpot Formerly Known as ArthritisPower","phase":"","overall_status":"UNKNOWN","enrollment_count":40000,"lead_sponsor_name":"Global Healthy Living Foundation","has_results":false},{"nct_id":"NCT03945968","title":"The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.","phase":"","overall_status":"RECRUITING","enrollment_count":16000,"lead_sponsor_name":"Russian Federation of Anesthesiologists and Reanimatologists","has_results":false},{"nct_id":"NCT06265714","title":"The IndONEsia ICCU Registry: a Multicenter Cohort of Intensive Cardiovascular Care Units Patients in Indonesia","phase":"","overall_status":"COMPLETED","enrollment_count":12950,"lead_sponsor_name":"Indonesia University","has_results":false},{"nct_id":"NCT07217522","title":"Rutgers University Study of the Genetics of Pulmonary Hypertension","phase":"","overall_status":"RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Rutgers, The State University of New Jersey","has_results":false},{"nct_id":"NCT05315908","title":"COVID-19 Testing in Underserved and Vulnerable Populations","phase":"NA","overall_status":"TERMINATED","enrollment_count":9120,"lead_sponsor_name":"Jesse Nodora","has_results":true},{"nct_id":"NCT07280325","title":"Moxie Self-Management and Education Support Program","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":9000,"lead_sponsor_name":"University of Calgary","has_results":false},{"nct_id":"NCT03749343","title":"International T1 Multicenter Outcome Study","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":8000,"lead_sponsor_name":"Johann Wolfgang Goethe University Hospital","has_results":false},{"nct_id":"NCT03461367","title":"CTO Registry From Insight of IVUS in Fuwai Hospital","phase":"","overall_status":"UNKNOWN","enrollment_count":5000,"lead_sponsor_name":"China National Center for Cardiovascular Diseases","has_results":false},{"nct_id":"NCT05690009","title":"Real Clinical Practice Register of AlbUminuRia Detection in Patients With Previously undiAgnosed Chronic Kidney Disease","phase":"","overall_status":"COMPLETED","enrollment_count":4580,"lead_sponsor_name":"Eurasian Association of Therapists","has_results":false},{"nct_id":"NCT07396792","title":"Screening for Cardiac and Cardiac-associated Pathology Using Single-channel Electrocardiogram","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":4000,"lead_sponsor_name":"I.M. Sechenov First Moscow State Medical University","has_results":false},{"nct_id":"NCT02668250","title":"Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mortality","phase":"NA","overall_status":"COMPLETED","enrollment_count":2495,"lead_sponsor_name":"Centre Hospitalier Universitaire de Saint Etienne","has_results":false},{"nct_id":"NCT03794531","title":"Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Harvard School of Public Health (HSPH)","has_results":false},{"nct_id":"NCT03563417","title":"ISCHEMIA-CTO Trial - Revascularisation or Optimal Medical Therapy of CTO","phase":"NA","overall_status":"RECRUITING","enrollment_count":1560,"lead_sponsor_name":"Aarhus University Hospital Skejby","has_results":false},{"nct_id":"NCT07476703","title":"Expanded Studies on the SCAPIS Stockholm Reexamination Cohort","phase":"","overall_status":"RECRUITING","enrollment_count":1400,"lead_sponsor_name":"Danderyd Hospital","has_results":false},{"nct_id":"NCT05786482","title":"Evidence Based Mental Wellness Programming Online for Adults Across Chronic Physical Conditions","phase":"NA","overall_status":"COMPLETED","enrollment_count":825,"lead_sponsor_name":"University of Alberta","has_results":false},{"nct_id":"NCT04218487","title":"Xuefu-Zhuyu Capsule for the Treatment of \"Qizhi Xueyu Zheng\" (Qi Stagnation and Blood Stasis Syndrome)","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":720,"lead_sponsor_name":"Zhong Wang","has_results":false},{"nct_id":"NCT06094491","title":"Virtual Diabetes Group Visits Across Health Systems","phase":"PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":720,"lead_sponsor_name":"University of Chicago","has_results":false},{"nct_id":"NCT06072287","title":"The Living With a Long-Term Condition Study","phase":"","overall_status":"UNKNOWN","enrollment_count":600,"lead_sponsor_name":"King's College London","has_results":false},{"nct_id":"NCT06407154","title":"Chronical Illness-related Limitations of the Ability to Cope with Rising Temperatures: an Observational Study, 2nd Wave","phase":"","overall_status":"COMPLETED","enrollment_count":578,"lead_sponsor_name":"Universitätsklinikum Hamburg-Eppendorf","has_results":false},{"nct_id":"NCT04141891","title":"Advancing Understanding of Transportation Options","phase":"NA","overall_status":"COMPLETED","enrollment_count":529,"lead_sponsor_name":"University of Colorado, Denver","has_results":true},{"nct_id":"NCT05045742","title":"Prediction of Patient Deterioration Using Machine Learning","phase":"","overall_status":"COMPLETED","enrollment_count":526,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false},{"nct_id":"NCT03835923","title":"Lifestyle Intervention in Chronic Ischemic Heart Disease and Diabetes","phase":"NA","overall_status":"COMPLETED","enrollment_count":502,"lead_sponsor_name":"Techniker Krankenkasse","has_results":false},{"nct_id":"NCT06728605","title":"Protective Effect of EECP Against Negative Inflammatory Response and Organ Dysfunction After Cardiovascular Surgery","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":400,"lead_sponsor_name":"Nanjing Medical University","has_results":false},{"nct_id":"NCT06374277","title":"Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence","phase":"NA","overall_status":"RECRUITING","enrollment_count":388,"lead_sponsor_name":"University of Tennessee","has_results":false},{"nct_id":"NCT06484647","title":"Comparing T-stenting And Minimal Protrusion With External Minicrush for Treatment of Complex Coronary Bifurcation","phase":"","overall_status":"RECRUITING","enrollment_count":382,"lead_sponsor_name":"San Luigi Gonzaga Hospital","has_results":false},{"nct_id":"NCT04849312","title":"Prediction of 30-Day Readmission Using Machine Learning","phase":"","overall_status":"COMPLETED","enrollment_count":372,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false},{"nct_id":"NCT05473702","title":"Smart Textile Sensor System for Health Monitoring","phase":"","overall_status":"COMPLETED","enrollment_count":334,"lead_sponsor_name":"Nanowear Inc.","has_results":false},{"nct_id":"NCT02713347","title":"Advancing Symptom Alleviation With Palliative Treatment","phase":"NA","overall_status":"COMPLETED","enrollment_count":306,"lead_sponsor_name":"VA Office of Research and Development","has_results":true},{"nct_id":"NCT04414267","title":"Bacillus Calmette-guérin Vaccination to Prevent COVID-19","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":301,"lead_sponsor_name":"Hellenic Institute for the Study of Sepsis","has_results":false},{"nct_id":"NCT04808596","title":"Pulmonary Hypertension Biorepository and Registry","phase":"","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"University of Kansas Medical Center","has_results":false},{"nct_id":"NCT02789800","title":"Patient-Centred Innovations for Persons With Multimorbidity - Quebec","phase":"NA","overall_status":"COMPLETED","enrollment_count":284,"lead_sponsor_name":"Université de Sherbrooke","has_results":false},{"nct_id":"NCT04876963","title":"HOLT-ED: Holter-monitoring in End-stage Renal Disease","phase":"","overall_status":"UNKNOWN","enrollment_count":268,"lead_sponsor_name":"Rigshospitalet, Denmark","has_results":false},{"nct_id":"NCT06890208","title":"Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures, Third Wave","phase":"","overall_status":"RECRUITING","enrollment_count":240,"lead_sponsor_name":"Universitätsklinikum Hamburg-Eppendorf","has_results":false},{"nct_id":"NCT04645732","title":"Personalized Exercise Therapy and Self-management Support for Patients With Multimorbidity","phase":"NA","overall_status":"COMPLETED","enrollment_count":228,"lead_sponsor_name":"University of Southern Denmark","has_results":false},{"nct_id":"NCT06909682","title":"AI-Based Monitoring System for Chronic Heart Failure With Advanced Wearable and Mini-Invasive Devices","phase":"","overall_status":"RECRUITING","enrollment_count":205,"lead_sponsor_name":"University of Salerno","has_results":false},{"nct_id":"NCT04790617","title":"ENCOMPASS: Expansion Study B, RCT","phase":"NA","overall_status":"COMPLETED","enrollment_count":183,"lead_sponsor_name":"University of Calgary","has_results":false},{"nct_id":"NCT03077386","title":"Enhancing Community Health Through Patient Navigation, Advocacy and Social Support","phase":"NA","overall_status":"COMPLETED","enrollment_count":176,"lead_sponsor_name":"University of Calgary","has_results":false},{"nct_id":"NCT02742597","title":"Patient-Centred Innovations for Persons With Multimorbidity - Ontario","phase":"NA","overall_status":"COMPLETED","enrollment_count":175,"lead_sponsor_name":"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","has_results":false},{"nct_id":"NCT06813482","title":"Real-World Evaluation of a Digitally Enabled Cardiac Rehabilitation Program","phase":"","overall_status":"COMPLETED","enrollment_count":172,"lead_sponsor_name":"Baker Heart and Diabetes Institute","has_results":false},{"nct_id":"NCT04080570","title":"Remote Physician Care for Home Hospital Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":172,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false},{"nct_id":"NCT06358508","title":"Sapphire 3 CTO Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":170,"lead_sponsor_name":"OrbusNeich","has_results":false},{"nct_id":"NCT05256303","title":"Rural Hospital-Level Care at Home for Acutely Ill Adults","phase":"NA","overall_status":"COMPLETED","enrollment_count":160,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false},{"nct_id":"NCT03988166","title":"Chronic Total Occlusion Percutaneous Coronary Intervention Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Vascular Solutions LLC","has_results":true},{"nct_id":"NCT06522074","title":"Evaluating the Role of IGF-1 and S-Klotho In Plaque Phenotype and Vulnerability: the VISION Study.","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":150,"lead_sponsor_name":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","has_results":false},{"nct_id":"NCT07471802","title":"Monitoring of the Sympathetic/Vagal Balance Through Multiparametric Analysis of Heart Rate Variability (HRV)","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":150,"lead_sponsor_name":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","has_results":false},{"nct_id":"NCT05209880","title":"Advance Care Planning in the Emergency Department","phase":"NA","overall_status":"COMPLETED","enrollment_count":141,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":true}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}