{"disease":{"id":"head-pain","name":"head pain"},"drugs":{"marketed":[{"drug_id":"sodium-sulfate","indication_name":"Migraine headache pain","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"SODIUM SULFATE","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":20,"revenue":null,"mechanism":null},{"drug_id":"sodium-sulfate","indication_name":"Headache pain with nausea","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"SODIUM SULFATE","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":20,"revenue":null,"mechanism":null}],"pipeline":[],"offLabel":[],"totalMarketed":2,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03537573","title":"Provider-Targeted Behavioral Interventions to Prevent Unsafe Opioid Prescribing for Acute Pain in Primary Care","phase":"NA","overall_status":"COMPLETED","enrollment_count":22616,"lead_sponsor_name":"University of Pittsburgh","has_results":false},{"nct_id":"NCT05247333","title":"Implementation of a Minor Ailment Service in Community Pharmacy Practice","phase":"NA","overall_status":"COMPLETED","enrollment_count":20987,"lead_sponsor_name":"Universidad de Granada","has_results":false},{"nct_id":"NCT04490798","title":"Effectiveness of Acupuncture Clinical Pathway","phase":"","overall_status":"COMPLETED","enrollment_count":3245,"lead_sponsor_name":"Hospital Son Llatzer","has_results":false},{"nct_id":"NCT06583395","title":"Quest to Analyze One Thousand Humans Meditating","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":3000,"lead_sponsor_name":"Tobias Moeller-Bertram","has_results":false},{"nct_id":"NCT04091321","title":"Association Between Chronic Headache and Back Pain With Childbirth","phase":"","overall_status":"COMPLETED","enrollment_count":1112,"lead_sponsor_name":"Stanford University","has_results":false},{"nct_id":"NCT07347028","title":"Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Knee Osteoarthritis(OA)","phase":"NA","overall_status":"RECRUITING","enrollment_count":1036,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT05754190","title":"Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA","phase":"","overall_status":"RECRUITING","enrollment_count":800,"lead_sponsor_name":"Brown University","has_results":false},{"nct_id":"NCT04393909","title":"Improving Safety of Diagnosis and Therapy in the Inpatient Setting","phase":"NA","overall_status":"COMPLETED","enrollment_count":700,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false},{"nct_id":"NCT05785988","title":"Anti-CGRP Monoclonal Antibody Response After Switching (AMARAS)","phase":"","overall_status":"UNKNOWN","enrollment_count":600,"lead_sponsor_name":"Hospital Clínico Universitario de Valladolid","has_results":false},{"nct_id":"NCT05325580","title":"Intravenous Magnesium Sulfate Vs Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":424,"lead_sponsor_name":"University of Monastir","has_results":false},{"nct_id":"NCT06918470","title":"Research on the Effect of Noise Cancelling Headphones in Reducing Postoperative Pain","phase":"NA","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Maternal and Child Health Hospital of Hubei Province","has_results":false},{"nct_id":"NCT03080779","title":"Long Term Outcomes After Accidental Dural Puncture ADP Study","phase":"","overall_status":"COMPLETED","enrollment_count":270,"lead_sponsor_name":"University Hospitals, Leicester","has_results":false},{"nct_id":"NCT05376163","title":"Validity of Headache Disability Index","phase":"","overall_status":"UNKNOWN","enrollment_count":250,"lead_sponsor_name":"Hacettepe University","has_results":false},{"nct_id":"NCT05619354","title":"Validity and Reliability of the Dutch HDI","phase":"","overall_status":"UNKNOWN","enrollment_count":250,"lead_sponsor_name":"University Ghent","has_results":false},{"nct_id":"NCT03612843","title":"Adverse Events in Dry Needling","phase":"","overall_status":"COMPLETED","enrollment_count":250,"lead_sponsor_name":"Elizabeth Lane","has_results":false},{"nct_id":"NCT05326802","title":"The U.S. Embryologist Fatigue Study","phase":"","overall_status":"COMPLETED","enrollment_count":246,"lead_sponsor_name":"TMRW Life Sciences","has_results":false},{"nct_id":"NCT06882278","title":"Pulsed Radiofrequency Combined With Platelet-Rich Plasma Applied to the Sphenopalatine Ganglion in Treating Episodic Cluster Headache","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":242,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT07051265","title":"Effect of Transcutaneous Electrical Nerve Stimulation or Acupressure on Pain in Patients With Head and Neck Cancer","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":240,"lead_sponsor_name":"Kaohsiung Veterans General Hospital.","has_results":false},{"nct_id":"NCT04715932","title":"Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN)","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":216,"lead_sponsor_name":"Montreal Heart Institute","has_results":true},{"nct_id":"NCT03844412","title":"Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":209,"lead_sponsor_name":"Duke University","has_results":true},{"nct_id":"NCT05446597","title":"SMART Concussion Trial: Symptom Management vs Alternative Randomized Treatment of Concussion Trial","phase":"NA","overall_status":"UNKNOWN","enrollment_count":164,"lead_sponsor_name":"University of Calgary","has_results":false},{"nct_id":"NCT04182659","title":"Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms","phase":"NA","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"Veterans Medical Research Foundation","has_results":false},{"nct_id":"NCT02926573","title":"Perioperative Gabapentin Use In Head And Neck Mucosal Surgery Patients","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":123,"lead_sponsor_name":"Washington University School of Medicine","has_results":true},{"nct_id":"NCT05708963","title":"The U.K. Embryologist Fatigue Study","phase":"","overall_status":"COMPLETED","enrollment_count":123,"lead_sponsor_name":"TMRW Life Sciences","has_results":false},{"nct_id":"NCT04287140","title":"The Effect of Intravenous Fluid Therapy in Acute Migraine Attacks","phase":"NA","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"Marmara University","has_results":false},{"nct_id":"NCT04717518","title":"Anchoring Patients Pain Scores in the Emergency Department","phase":"","overall_status":"COMPLETED","enrollment_count":108,"lead_sponsor_name":"CHRISTUS Health","has_results":false},{"nct_id":"NCT04217616","title":"Pain Perception of People Who Are Unable to Have Headache","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"Danish Headache Center","has_results":false},{"nct_id":"NCT05704335","title":"InfluenCEF Study: Study on the Headache Associated With Influenza Infection","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Hospital Clínico Universitario de Valladolid","has_results":false},{"nct_id":"NCT07155109","title":"Different Intraperitoneal Pressures on Optic Nerve Sheath Diameter in Laparoscopic Surgeries","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":100,"lead_sponsor_name":"Diskapi Yildirim Beyazit Education and Research Hospital","has_results":false},{"nct_id":"NCT05475769","title":"NUMITOR Study: Nummular Headache Iberian Study on the Treatments and Outcomes in Real-World Setting","phase":"","overall_status":"UNKNOWN","enrollment_count":98,"lead_sponsor_name":"Hospital Clínico Universitario de Valladolid","has_results":false},{"nct_id":"NCT04242290","title":"Cervicospinal Posture and Pain in Cervicogenic Headache","phase":"","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Hitit University","has_results":false},{"nct_id":"NCT07233538","title":"Preoperative Maxillary Nerve Block and Remifentanil Use in Septorhinoplasty","phase":"NA","overall_status":"RECRUITING","enrollment_count":90,"lead_sponsor_name":"Ankara Etlik City Hospital","has_results":false},{"nct_id":"NCT05891808","title":"miR-155 Expression in Episodic and Chronic Migraine","phase":"","overall_status":"UNKNOWN","enrollment_count":90,"lead_sponsor_name":"IRCCS National Neurological Institute \"C. Mondino\" Foundation","has_results":false},{"nct_id":"NCT04138316","title":"CandeSpartan Study. Candesartan Spanish Response-prediction and Tolerability Study","phase":"","overall_status":"COMPLETED","enrollment_count":85,"lead_sponsor_name":"Hospital Clínico Universitario de Valladolid","has_results":false},{"nct_id":"NCT04151576","title":"Aromatherapy Massage in Migraine Attacks","phase":"NA","overall_status":"COMPLETED","enrollment_count":83,"lead_sponsor_name":"Biruni University","has_results":false},{"nct_id":"NCT03066037","title":"Regional-anaesthesiological Infiltration Techniques for the Management of Chronic Pain: a Retrospective Study","phase":"","overall_status":"COMPLETED","enrollment_count":83,"lead_sponsor_name":"Charite University, Berlin, Germany","has_results":false},{"nct_id":"NCT03223298","title":"Botulinum Toxin Versus Placebo Injections to Temporalis and Masseter Muscles","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Weill Medical College of Cornell University","has_results":true},{"nct_id":"NCT07292181","title":"Central Sensitization and Neuropathic Pain in Cervicogenic Headache","phase":"","overall_status":"COMPLETED","enrollment_count":72,"lead_sponsor_name":"Gulseren Demir Karakilic","has_results":false},{"nct_id":"NCT04702308","title":"Non-Interruptive Alerts for Improving Use of Clinical Decision Rules","phase":"NA","overall_status":"COMPLETED","enrollment_count":70,"lead_sponsor_name":"University of Utah","has_results":false},{"nct_id":"NCT05381012","title":"Fibromyalgia Syndrome on Patients With Chronic Migraine","phase":"NA","overall_status":"COMPLETED","enrollment_count":66,"lead_sponsor_name":"Istanbul University - Cerrahpasa","has_results":false},{"nct_id":"NCT03429738","title":"Single-Dose Bioavailability Study of Two Formulations of Ibuprofen and Pseudoephedrine Hydrochloride Tablets","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":66,"lead_sponsor_name":"Institut für Pharmakologie und Präventive Medizin","has_results":false},{"nct_id":"NCT05414799","title":"Effect of Exercises on Computer Vision Syndrome","phase":"NA","overall_status":"UNKNOWN","enrollment_count":66,"lead_sponsor_name":"Shifa Tameer-e-Millat University","has_results":false},{"nct_id":"NCT05381129","title":"The Effect of Accompanying Temporomandibular Joint Dysfunction in Patients With Chronic Migraine","phase":"NA","overall_status":"COMPLETED","enrollment_count":62,"lead_sponsor_name":"Istanbul University - Cerrahpasa","has_results":false},{"nct_id":"NCT05712655","title":"Masticatory Muscles Electromyography in Post-pubertal Females With Forward Head Posture and Temporomandibular Disorders","phase":"","overall_status":"COMPLETED","enrollment_count":61,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT06264102","title":"Influence of Dalcroze Eurhythmics on Pains in Older Women","phase":"NA","overall_status":"COMPLETED","enrollment_count":61,"lead_sponsor_name":"Poznan University of Physical Education","has_results":false},{"nct_id":"NCT02531906","title":"Gabapentin, Methadone Hydrochloride, and Oxycodone Hydrochloride in Improving Quality of Life in Patients With Stage II-IV Head and Neck Cancer During Chemoradiation","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Roswell Park Cancer Institute","has_results":false},{"nct_id":"NCT04356963","title":"Adjunct VR Pain Management in Acute Brain Injury","phase":"NA","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"University of Maryland, Baltimore","has_results":true},{"nct_id":"NCT07310823","title":"Mangement of Cervicogenic Headache by Maual Therapy","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":57,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT04145180","title":"Effectiveness of a Physical Recovery Program for Head and Neck Cancer Patients (3C-CUIDATE)","phase":"NA","overall_status":"COMPLETED","enrollment_count":55,"lead_sponsor_name":"Universidad de Granada","has_results":false},{"nct_id":"NCT06407089","title":"Effectiveness of a Telerehabilitation Program Based on Specific Neck Exercises in Patients With Forward Head Posture.","phase":"NA","overall_status":"COMPLETED","enrollment_count":52,"lead_sponsor_name":"Universitat Internacional de Catalunya","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}