{"disease":{"id":"glioma-of-brain","name":"glioma of brain"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03750890","title":"Visual Study of Molecular Genotype in Glioma Evolution","phase":"","overall_status":"UNKNOWN","enrollment_count":1000,"lead_sponsor_name":"Tongji Hospital","has_results":false},{"nct_id":"NCT03849430","title":"Longitudinal Analysis of the Health-related Quality of Life in Glioma Patients","phase":"","overall_status":"RECRUITING","enrollment_count":750,"lead_sponsor_name":"Universitaire Ziekenhuizen KU Leuven","has_results":false},{"nct_id":"NCT03650257","title":"A Large-scale Research for Immunotherapy of Glioblastoma With Autologous Heat Shock Protein gp96","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"Cure&Sure Biotech Co., LTD","has_results":false},{"nct_id":"NCT03935685","title":"Pilot Study of Mirtazapine for the Dual Tx of Depression and CINV in High-Grade Glioma Pts on TMZ","phase":"PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":120,"lead_sponsor_name":"University of California, Irvine","has_results":false},{"nct_id":"NCT03423992","title":"Personalized Chimeric Antigen Receptor T Cell Immunotherapy for Patients With Recurrent Malignant Gliomas","phase":"PHASE1","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Xuanwu Hospital, Beijing","has_results":false},{"nct_id":"NCT03180697","title":"The Efficacy of APT Magnetic Resonance Imaging in Predicting the Efficacy of Bevacizumab in Recurrent Malignant Gliomas","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Zhujiang Hospital","has_results":false},{"nct_id":"NCT04196413","title":"GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG)","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":97,"lead_sponsor_name":"Stanford University","has_results":false},{"nct_id":"NCT07110246","title":"Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":96,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT00628940","title":"PET Imaging of High-grade Glioma Using 18F-fluoromethylcholine: a Tool for the Early Detection of Tumour Recurrence After Combined Radiochemotherapy?","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"University Ghent","has_results":false},{"nct_id":"NCT06417281","title":"Photodynamic Diagnosis for Malignant Brain Glioma With 5-Aminolevulinic Acid（5-ALA）","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":86,"lead_sponsor_name":"Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.","has_results":false},{"nct_id":"NCT03534050","title":"Neuropsychological and Oncological Outcomes in Grade 2 or 3 Glioma Patients Undergoing Postoperative Modern Radiotherapy","phase":"PHASE2, PHASE3","overall_status":"RECRUITING","enrollment_count":80,"lead_sponsor_name":"Chang Gung Memorial Hospital","has_results":false},{"nct_id":"NCT03434262","title":"SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":68,"lead_sponsor_name":"St. Jude Children's Research Hospital","has_results":false},{"nct_id":"NCT04201457","title":"A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration","phase":"PHASE1, PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":57,"lead_sponsor_name":"Pediatric Brain Tumor Consortium","has_results":false},{"nct_id":"NCT03154801","title":"Early Detection and Paramedical Care of Sexual Difficulties in Nervous System Diseases: Example of Multiple Sclerosis and Brain Tumors (NEUROSEX)","phase":"NA","overall_status":"UNKNOWN","enrollment_count":54,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT03102112","title":"Noninvasively Predicting Gene Status of Glioma","phase":"","overall_status":"UNKNOWN","enrollment_count":50,"lead_sponsor_name":"Tang-Du Hospital","has_results":false},{"nct_id":"NCT03739372","title":"Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":44,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT07506239","title":"Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma","phase":"NA","overall_status":"RECRUITING","enrollment_count":40,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT07210632","title":"Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)","phase":"EARLY_PHASE1","overall_status":"NOT_YET_RECRUITING","enrollment_count":38,"lead_sponsor_name":"Eben Rosenthal","has_results":false},{"nct_id":"NCT03194906","title":"Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":34,"lead_sponsor_name":"St. Jude Children's Research Hospital","has_results":false},{"nct_id":"NCT03496181","title":"Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently","phase":"","overall_status":"COMPLETED","enrollment_count":32,"lead_sponsor_name":"Memorial Sloan Kettering Cancer Center","has_results":false},{"nct_id":"NCT03392545","title":"Combination of Immunization and Radiotherapy for Malignant Gliomas (InSituVac1)","phase":"PHASE1","overall_status":"UNKNOWN","enrollment_count":30,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT04091503","title":"Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastoma","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Center Trials & Treatment Europe","has_results":false},{"nct_id":"NCT03834740","title":"A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection","phase":"EARLY_PHASE1","overall_status":"COMPLETED","enrollment_count":27,"lead_sponsor_name":"St. Joseph's Hospital and Medical Center, Phoenix","has_results":true},{"nct_id":"NCT03779230","title":"Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III / IV Glioma at First Relapse","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":20,"lead_sponsor_name":"Philogen S.p.A.","has_results":false},{"nct_id":"NCT03916757","title":"V-Boost Immunotherapy in Glioblastoma Multiforme Brain Cancer","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":20,"lead_sponsor_name":"Immunitor LLC","has_results":false},{"nct_id":"NCT03355794","title":"A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":19,"lead_sponsor_name":"Children's Hospital Medical Center, Cincinnati","has_results":false},{"nct_id":"NCT03665545","title":"Pembrolizumab in Association With the IMA950/Poly-ICLC for Relapsing Glioblastoma","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":18,"lead_sponsor_name":"University Hospital, Geneva","has_results":false},{"nct_id":"NCT03698162","title":"Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases","phase":"NA","overall_status":"TERMINATED","enrollment_count":15,"lead_sponsor_name":"University of Southern California","has_results":false},{"nct_id":"NCT04063514","title":"The Use of Focused Ultrasound and DCE K-trans Imaging to Evaluate Permeability of the Blood-Brain Barrier","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":15,"lead_sponsor_name":"Neurological Associates of West Los Angeles","has_results":false},{"nct_id":"NCT02967380","title":"Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases","phase":"NA","overall_status":"TERMINATED","enrollment_count":14,"lead_sponsor_name":"University of Southern California","has_results":false},{"nct_id":"NCT01550523","title":"Pilot Immunotherapy Trial for Recurrent Malignant Gliomas","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":13,"lead_sponsor_name":"Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University","has_results":false},{"nct_id":"NCT04135807","title":"Implantable Microdevice In Primary Brain Tumors","phase":"EARLY_PHASE1","overall_status":"RECRUITING","enrollment_count":12,"lead_sponsor_name":"Oliver Jonas","has_results":false},{"nct_id":"NCT04937244","title":"Pilot Study Evaluating the Optimization of the ORBEYE Blue Light Filter During Fluorescence-Guided Resection of Gliomas","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":10,"lead_sponsor_name":"Northwell Health","has_results":false},{"nct_id":"NCT03011671","title":"Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant Glioma","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":10,"lead_sponsor_name":"University of Chicago","has_results":false},{"nct_id":"NCT04859725","title":"HyperSpectral Imaging in Low Grade Glioma","phase":"NA","overall_status":"RECRUITING","enrollment_count":10,"lead_sponsor_name":"Universitaire Ziekenhuizen KU Leuven","has_results":false},{"nct_id":"NCT04222309","title":"Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM)","phase":"PHASE1","overall_status":"SUSPENDED","enrollment_count":10,"lead_sponsor_name":"Northwell Health","has_results":false},{"nct_id":"NCT03043391","title":"Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":8,"lead_sponsor_name":"Istari Oncology, Inc.","has_results":true},{"nct_id":"NCT03717142","title":"Feasibility of the LUM Imaging System for Detection of Cancer to the Brain","phase":"NA","overall_status":"TERMINATED","enrollment_count":4,"lead_sponsor_name":"Lumicell, Inc.","has_results":false},{"nct_id":"NCT03436433","title":"Seizure Prophylaxis in Patients With Glioma or Brain Metastasis","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":4,"lead_sponsor_name":"Duke University","has_results":true},{"nct_id":"NCT03927274","title":"Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma","phase":"EARLY_PHASE1","overall_status":"TERMINATED","enrollment_count":3,"lead_sponsor_name":"H. Lee Moffitt Cancer Center and Research Institute","has_results":false},{"nct_id":"NCT06193174","title":"Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)","phase":"PHASE1","overall_status":"TERMINATED","enrollment_count":1,"lead_sponsor_name":"University of Alabama at Birmingham","has_results":false},{"nct_id":"NCT06648473","title":"Repeatability of Magnetic Resonance Imaging in Patients With IDH1 Mutant Glioma on Ivosidenib","phase":"NA","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"Duke University","has_results":false},{"nct_id":"NCT03796507","title":"Early Temozolomide in Patients With High-Grade Gliomas in Rehabilitation","phase":"EARLY_PHASE1","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"University of Rochester","has_results":false},{"nct_id":"NCT04406610","title":"CAR-T Cell Immunotherapy for GD2 Positive Glioma Patients","phase":"PHASE1, PHASE2","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"Fuda Cancer Hospital, Guangzhou","has_results":false},{"nct_id":"NCT04482933","title":"HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma","phase":"PHASE2","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"Pediatric Brain Tumor Consortium","has_results":false},{"nct_id":"NCT03311542","title":"Expanded Access for Pembrolizumab (MK-3475)","phase":"","overall_status":"NO_LONGER_AVAILABLE","enrollment_count":null,"lead_sponsor_name":"Center Trials & Treatment","has_results":false},{"nct_id":"NCT03460782","title":"An Expanded Access Program of Ipilimumab for Patients With Glioblastomas and Gliomas","phase":"","overall_status":"NO_LONGER_AVAILABLE","enrollment_count":null,"lead_sponsor_name":"Center Trials & Treatment","has_results":false}],"total":47},"guidelines":[],"source":"Drug Landscape verified database"}