{"disease":{"id":"genetic-mutation","name":"genetic mutation"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05721326","title":"Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition","phase":"NA","overall_status":"COMPLETED","enrollment_count":1330,"lead_sponsor_name":"Abramson Cancer Center at Penn Medicine","has_results":false},{"nct_id":"NCT03538639","title":"Vascular Disease Discovery Protocol","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"National Heart, Lung, and Blood Institute (NHLBI)","has_results":false},{"nct_id":"NCT06584994","title":"Investigating the Role of Genetics in Disease Predisposition","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":1000,"lead_sponsor_name":"The Wellcome Sanger Institute","has_results":false},{"nct_id":"NCT04574297","title":"An Observational Study on the Natural Course of Chronic Pancreatitis","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":798,"lead_sponsor_name":"Changhai Hospital","has_results":true},{"nct_id":"NCT04788927","title":"Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":400,"lead_sponsor_name":"Rigshospitalet, Denmark","has_results":false},{"nct_id":"NCT04830787","title":"Correlation Between Myocardial Deformation and Coronary Artery Tortuosity in Patients With Hypertrophic Cardiomyopathy","phase":"","overall_status":"COMPLETED","enrollment_count":302,"lead_sponsor_name":"Henan Provincial People's Hospital","has_results":false},{"nct_id":"NCT06277466","title":"Effect of Mutations in T2DM Susceptibility Genes on the Expression of Susceptibility Genes in Patients With T2DM and Controls","phase":"NA","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"The Affiliated Hospital of Xuzhou Medical University","has_results":false},{"nct_id":"NCT05364294","title":"Molecular Diagnosis of Systemic Autoinflammatory Diseases","phase":"","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Institut National de la Santé Et de la Recherche Médicale, France","has_results":false},{"nct_id":"NCT05898009","title":"Contribution of Oncogenetics in Breast Cancer in Reunion Epidemiology of Breast Cancer in Reunion: Study of the Reunion Mutation on BRCA2","phase":"NA","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Centre Hospitalier Universitaire de la Réunion","has_results":false},{"nct_id":"NCT02202291","title":"Prospective Multicenter Study on the Identification of Genetic Abnormalities Predisposing to Vasospasm From a Privileged Model: the Primary Raynaud's Phenomenon","phase":"NA","overall_status":"COMPLETED","enrollment_count":258,"lead_sponsor_name":"Nantes University Hospital","has_results":false},{"nct_id":"NCT03234478","title":"Parkinson Disease and DBS: Cognitive Effects in GBA Mutation Carriers","phase":"","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Rutgers, The State University of New Jersey","has_results":false},{"nct_id":"NCT04481152","title":"Impact of Environmental Exposures on Tumor Risk in Subjects at Risk of Hereditary SDHx Paraganglioma","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT07493096","title":"Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders","phase":"","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"Healing Hope International","has_results":false},{"nct_id":"NCT05735717","title":"MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":70,"lead_sponsor_name":"Masonic Cancer Center, University of Minnesota","has_results":false},{"nct_id":"NCT03309605","title":"Phase 1 Study of ELX-02 in Healthy Adult Subjects","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":62,"lead_sponsor_name":"Eloxx Pharmaceuticals, Inc.","has_results":true},{"nct_id":"NCT03043508","title":"Overall and Disease Specific Survival in Patients With Confirmed MEN1 With or Without PNET (Pancreatic Neuroendocrine Tumors)","phase":"","overall_status":"UNKNOWN","enrollment_count":45,"lead_sponsor_name":"M.D. Anderson Cancer Center","has_results":false},{"nct_id":"NCT06792721","title":"MEASUREMENT OF CIRCULATING MUTATION BURDEN","phase":"","overall_status":"RECRUITING","enrollment_count":30,"lead_sponsor_name":"Centre Francois Baclesse","has_results":false},{"nct_id":"NCT05771454","title":"Frequency of Occult Breast Cancer After Prophylactic Mastectomy Among High-Penetrance Breast Cancer Gene Positives","phase":"","overall_status":"COMPLETED","enrollment_count":26,"lead_sponsor_name":"Aga Khan University Hospital, Pakistan","has_results":false},{"nct_id":"NCT04811274","title":"Macrophages, GM-CSF and MARS Proteinosis","phase":"","overall_status":"COMPLETED","enrollment_count":20,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT06470685","title":"Prophylactic Prostatectomy for Prostate Cancer (PPPC)","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":20,"lead_sponsor_name":"Royal Marsden NHS Foundation Trust","has_results":false},{"nct_id":"NCT03292302","title":"Phase 1 Study of ELX-02 in Healthy Adults","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":18,"lead_sponsor_name":"Eloxx Pharmaceuticals, Inc.","has_results":false},{"nct_id":"NCT04069260","title":"A Phase 2 Study of ELX-02 in Patients With Nephropathic Cystinosis","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":3,"lead_sponsor_name":"Eloxx Pharmaceuticals, Inc.","has_results":false},{"nct_id":"NCT02985658","title":"Expanded Access With ABT-888 (Veliparib) to Treat Metastatic Breast Cancer","phase":"","overall_status":"NO_LONGER_AVAILABLE","enrollment_count":null,"lead_sponsor_name":"University of Washington","has_results":false}],"total":23},"guidelines":[],"source":"Drug Landscape verified database"}