{"disease":{"id":"extravasation","name":"extravasation"},"drugs":{"marketed":[{"drug_id":"razoxane","indication_name":"Extravasation Injury from Anthracycline Injection","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Razoxin","generic_name":"RAZOXANE","company_name":"","drug_phase":"phase_2","molecular_target":"","drug_class":"","quality_score":null,"revenue":null,"mechanism":"Razoxin works by chelating iron and preventing the formation of free radicals that damage heart tissue."},{"drug_id":"dexrazoxane","indication_name":"Extravasation Injury from Anthracycline Injection","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Zinecard","generic_name":"DEXRAZOXANE","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"DNA topoisomerase 2-alpha","drug_class":"Cytoprotective Agent","quality_score":10,"revenue":null,"mechanism":"Zinecard works by binding to metal ions and preventing them from causing damage to DNA during anthracycline treatment."},{"drug_id":"zinecard","indication_name":"Extravasation Injury from Anthracycline Injection","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"Zinecard","company_name":"M.D. Anderson Cancer Center","drug_phase":"phase_1","molecular_target":"DNA topoisomerase 2-beta, DNA topoisomerase 2-alpha","drug_class":"","quality_score":null,"revenue":null,"mechanism":null}],"pipeline":[],"offLabel":[],"totalMarketed":3,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT02598609","title":"SEPREVEN: a Stepped-wedge Randomised Controlled Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":8000,"lead_sponsor_name":"Dr Caeymaex Laurence","has_results":false},{"nct_id":"NCT06758011","title":"ivWatch in Prevention of Extravasation of Vesicants in an Oncology Setting","phase":"NA","overall_status":"COMPLETED","enrollment_count":2400,"lead_sponsor_name":"Roswell Park Cancer Institute","has_results":false},{"nct_id":"NCT06859242","title":"Risk Prediction Model for Iodinated Contrast Medium Extravasation","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Zhang Wenyan","has_results":false},{"nct_id":"NCT07524608","title":"Implementing an Evidence-based, Standardized Care Bundle Targeting Register Nurses and Anaesthesiologists, to Enhance Patient Safety and Quality of Intravascular Access Devices Care Management - The Safe-IVADs Project. A Longitudinell Implementation Intervention With an Embedded Process Evaluation.","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":700,"lead_sponsor_name":"Sahlgrenska University Hospital","has_results":false},{"nct_id":"NCT06615063","title":"Limb Splinting for Intravenous Cannulae in Neonates and Its Effects on Life Span of Intravenous Cannulae","phase":"NA","overall_status":"COMPLETED","enrollment_count":246,"lead_sponsor_name":"Rawalpindi Medical College","has_results":false},{"nct_id":"NCT04321447","title":"Clinical Practice Guideline for Neonatal Extravasation Injury","phase":"NA","overall_status":"COMPLETED","enrollment_count":213,"lead_sponsor_name":"United Christian Hospital","has_results":false},{"nct_id":"NCT07046624","title":"Prevention of Phlebitis, Infiltration and Extravasation With Infusion Monitoring System","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":102,"lead_sponsor_name":"Ordu University","has_results":false},{"nct_id":"NCT03889678","title":"Color Doppler and Peripheral Venous Catheters","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"Augusta University","has_results":false},{"nct_id":"NCT03167814","title":"Prevention of Chyle-leak After Major Pancreatic Surgery","phase":"NA","overall_status":"UNKNOWN","enrollment_count":96,"lead_sponsor_name":"Helsinki University Central Hospital","has_results":false},{"nct_id":"NCT03426735","title":"Study of Iodine Contrast Media Extravasation","phase":"NA","overall_status":"COMPLETED","enrollment_count":65,"lead_sponsor_name":"Hospital de Sant Pau","has_results":false},{"nct_id":"NCT05638971","title":"Optical Detection Infiltration/Extravasation in Neonates (ODINE)","phase":"NA","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","has_results":false}],"total":11},"guidelines":[],"source":"Drug Landscape verified database"}