{"disease":{"id":"esketamine","name":"esketamine"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04834427","title":"Safety and Efficacy Evaluation of S (+) - Ketamine in Children","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":3000,"lead_sponsor_name":"Chinese PLA General Hospital","has_results":false},{"nct_id":"NCT04425473","title":"Esketamine and Perioperative Depressive Symptoms","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":435,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT06566469","title":"Dexmedetomidine-esketamine Combined Nasal Administration and Emergence Delirium","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":340,"lead_sponsor_name":"Peking University First Hospital","has_results":false},{"nct_id":"NCT04860661","title":"Esketamine on Postpartum Depression in Cesarean Section Women","phase":"NA","overall_status":"COMPLETED","enrollment_count":336,"lead_sponsor_name":"Ailin Luo","has_results":false},{"nct_id":"NCT07145775","title":"Dexmedetomidine-esketamine-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"Peking University First Hospital","has_results":false},{"nct_id":"NCT06633315","title":"Esketamine Combined With Dexmedetomidine Sedation in Head MRI Examination of Children With Autism Spectrum Disorder","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"Maternal and Child Health Hospital of Hubei Province","has_results":false},{"nct_id":"NCT06398834","title":"Esketamine and Butorphanol for Post-Lobectomy Pain","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":223,"lead_sponsor_name":"Second People's Hospital of Hefei City","has_results":false},{"nct_id":"NCT07247968","title":"Subanesthetic Esketamine in Modified ECT for Severe Depression in Adolescents: Clinical and Mechanistic Study","phase":"EARLY_PHASE1","overall_status":"RECRUITING","enrollment_count":220,"lead_sponsor_name":"Min Su","has_results":false},{"nct_id":"NCT05718544","title":"Mini-dose Esketamine-dexmedetomidine Supplemented Analgesia and Long-term Outcomes","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":199,"lead_sponsor_name":"Peking University First Hospital","has_results":false},{"nct_id":"NCT06530706","title":"Effect of Esketamine on Anxiety State in Patients Undergoing Abdominal Tumor Surgery","phase":"NA","overall_status":"COMPLETED","enrollment_count":185,"lead_sponsor_name":"Zhejiang Cancer Hospital","has_results":false},{"nct_id":"NCT06773143","title":"Effect of Subanesthetic Dose of Esketamine on Sleep Quality","phase":"NA","overall_status":"RECRUITING","enrollment_count":184,"lead_sponsor_name":"Nanjing First Hospital, Nanjing Medical University","has_results":false},{"nct_id":"NCT05732064","title":"Dexmedetomidine-esketamine Combined Nasal Administration and Perioperative Sleep Quality","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":180,"lead_sponsor_name":"Peking University First Hospital","has_results":false},{"nct_id":"NCT05718024","title":"Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality in ICU Patients","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":174,"lead_sponsor_name":"Peking University First Hospital","has_results":false},{"nct_id":"NCT06451627","title":"Esketamine on Postoperative Sleep Disturbance of Patients Undergoing Spinal Surgery","phase":"NA","overall_status":"RECRUITING","enrollment_count":156,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT07050212","title":"Application of Remimazolam, Dexmedetomidine, and Esketamine in Pediatric Preoperative Sedation","phase":"NA","overall_status":"RECRUITING","enrollment_count":150,"lead_sponsor_name":"Maternal and Child Health Hospital of Hubei Province","has_results":false},{"nct_id":"NCT06117917","title":"Esketamine Combined With Pregabalin on CPSP in Spinal Patients.","phase":"PHASE2, PHASE3","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT05283408","title":"The Clinical Study of Dexmedetomidine and Esketamine Combined Infusion Undergoing Modified Radical Mastectomy","phase":"NA","overall_status":"COMPLETED","enrollment_count":135,"lead_sponsor_name":"Anqing Municipal Hospital","has_results":false},{"nct_id":"NCT06822088","title":"Effects of Esketamine on Oxygenation and Quality of Recovery in Patients Undergoing Thoracoscopic Surgery","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":126,"lead_sponsor_name":"Jinqiao Qian","has_results":false},{"nct_id":"NCT06613243","title":"Different Doses of Dexmedetomidine Combined With Esketamine in Women Undergoing Cesarean Delivery","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"Peking University First Hospital","has_results":false},{"nct_id":"NCT07125573","title":"The Effect of Esketamine Combined With Dexmedetomidine on Postoperative Recovery Quality in Patients Undergoing Thoracoscopic Surgery","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":120,"lead_sponsor_name":"First Affiliated Hospital of Kunming Medical University","has_results":false},{"nct_id":"NCT05506787","title":"The Effects of Intraoperative Esketamine on Postoperative Pain and Mood in Patients With Inflammatory Bowel Disease","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"Jinling Hospital, China","has_results":false},{"nct_id":"NCT06389344","title":"Effect of Esketamine on Conscious State in Patients With pDoC","phase":"NA","overall_status":"RECRUITING","enrollment_count":116,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT07230171","title":"The Efficacy and Safety of Short Term S-ketamine Infusion as an Adjunctive Therapy in Patients With Fibromyalgia","phase":"NA","overall_status":"RECRUITING","enrollment_count":106,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT05289440","title":"Esketamine Administration on Recovery Quality After Radical Mastectomy","phase":"NA","overall_status":"COMPLETED","enrollment_count":105,"lead_sponsor_name":"Anqing Municipal Hospital","has_results":false},{"nct_id":"NCT06414941","title":"The Effect of Dexmedetomidine and Esketamine Combined Infusion Quality of Sleep Undergoing Modified Radical Mastectomy","phase":"NA","overall_status":"RECRUITING","enrollment_count":105,"lead_sponsor_name":"Anqing Municipal Hospital","has_results":false},{"nct_id":"NCT06543563","title":"Esketamine in Microelectrode Recording-guided Subthalamic Deep-Brain Stimulation for Parkinson's Disease","phase":"NA","overall_status":"RECRUITING","enrollment_count":102,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT04843982","title":"Immunoinflammatory Regulation of Esketamine in Septic Patients","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"Union Hospital, Tongji Medical College, Huazhong University of Science and Technology","has_results":false},{"nct_id":"NCT05096468","title":"Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms.","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Beijing Tiantan Hospital","has_results":false},{"nct_id":"NCT06574945","title":"Anesthesia for Loop Electrosurgical Excision Procedure (LEEP).","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Qian Wu","has_results":false},{"nct_id":"NCT06003218","title":"Dexmedetomidine-esketamine for Percutaneous Radiofrequency Liver Ablation","phase":"NA","overall_status":"COMPLETED","enrollment_count":88,"lead_sponsor_name":"Peking University First Hospital","has_results":false},{"nct_id":"NCT05458453","title":"An Exploratory Study of Esketamine in Patients After Thoracoscopic Surgery","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":80,"lead_sponsor_name":"The Second Affiliated Hospital of Chongqing Medical University","has_results":false},{"nct_id":"NCT06853431","title":"Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine for Preoperative Sedation in Pediatric General Anesthesia","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":80,"lead_sponsor_name":"Second Affiliated Hospital of Wenzhou Medical University","has_results":false},{"nct_id":"NCT07062601","title":"Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing Children","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":64,"lead_sponsor_name":"Anqing Municipal Hospital","has_results":false},{"nct_id":"NCT05943028","title":"Effect of Subanesthetic Dose Esketamine on Propofol-refentanil Closed-loop Targeted Controlled Infusion","phase":"EARLY_PHASE1","overall_status":"UNKNOWN","enrollment_count":48,"lead_sponsor_name":"bo xu","has_results":false},{"nct_id":"NCT04664530","title":"The Study on the Esketamine in the Treatment of Postherpetic Neuralgia","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":48,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT05809804","title":"Median Effective Dose of Esketamine Pretreatment to Prevent Sufentanil-induced Cough","phase":"NA","overall_status":"UNKNOWN","enrollment_count":30,"lead_sponsor_name":"Yangzhou University","has_results":false}],"total":36},"guidelines":[],"source":"Drug Landscape verified database"}