{"disease":{"id":"enteral-nutrition","name":"enteral nutrition"},"drugs":{"marketed":[{"drug_id":"soybean-oil","indication_name":"Parenteral Nutrition","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"SOYBEAN OIL","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"Lipid Emulsion [EPC]","quality_score":30,"revenue":null,"mechanism":null}],"pipeline":[{"drug_id":"olimel-7-6-e-periolimel-2-5-e","indication_name":"Parenteral nutrition support in critically ill patients","indication_type":"pipeline","phase":"Research/Development","line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"OLIMEL 7,6%E / PeriOLIMEL 2,5%E","company_name":"RWTH Aachen University","drug_phase":"discontinued","molecular_target":"Systemic metabolic support via balanced macronutrient delivery","drug_class":"Parenteral nutrition emulsion","quality_score":null,"revenue":null,"mechanism":"Parenteral nutrition emulsion providing balanced amino acids, glucose, lipids, and electrolytes for intravenous metabolic support in patients unable to tolerate enteral feeding."}],"offLabel":[],"totalMarketed":1,"totalPipeline":1},"trials":{"data":[{"nct_id":"NCT03278847","title":"Optimising Newborn Nutrition During Therapeutic Hypothermia.","phase":"","overall_status":"COMPLETED","enrollment_count":6030,"lead_sponsor_name":"Imperial College London","has_results":true},{"nct_id":"NCT03284398","title":"Three-Chamber Bags Retrospective Study in Spain","phase":"","overall_status":"COMPLETED","enrollment_count":3723,"lead_sponsor_name":"Fresenius Kabi","has_results":true},{"nct_id":"NCT07038538","title":"Evidence-based Practice in the Management of Gastric Tube Placement in Children","phase":"NA","overall_status":"RECRUITING","enrollment_count":2750,"lead_sponsor_name":"Children's Hospital of Fudan University","has_results":false},{"nct_id":"NCT04035551","title":"Health Evaluation And Learning for Total Parenteral Nutrition (TPN) at Home Patient Registry","phase":"","overall_status":"UNKNOWN","enrollment_count":1700,"lead_sponsor_name":"Coram Clinical Trials","has_results":false},{"nct_id":"NCT03335345","title":"Non-inferiority Study of the Pursuit of Enteral Nutrition Compared to a Strategy of Gastric Emptiness Peri-extubation. Cluster Randomized Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":1148,"lead_sponsor_name":"Centre Hospitalier le Mans","has_results":false},{"nct_id":"NCT05347888","title":"How Well do we Feed the Critically Ill Patients","phase":"","overall_status":"COMPLETED","enrollment_count":1000,"lead_sponsor_name":"NMC Specialty Hospital","has_results":false},{"nct_id":"NCT07085455","title":"The Effect of the Timing of Supplemental Parenteral Nutrition on the Prognosis of Critically Ill Patients (T-SPN)","phase":"NA","overall_status":"RECRUITING","enrollment_count":946,"lead_sponsor_name":"Dong Zhang","has_results":false},{"nct_id":"NCT04234490","title":"Longitudinal Evaluation of the Impact of Parenteral Nutrition","phase":"","overall_status":"COMPLETED","enrollment_count":912,"lead_sponsor_name":"University of Manchester","has_results":false},{"nct_id":"NCT04954755","title":"Development and Validation of a Prediction Model for Refeeding Syndrome in ICU Patients Undergoing Enteral Nutrition Patients","phase":"","overall_status":"COMPLETED","enrollment_count":553,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT07521111","title":"Predictive Value of Gastrointestinal Blood Flow for Enteral Nutrition Intolerance in Critically Ill Patients","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Ruijin Hospital","has_results":false},{"nct_id":"NCT03098537","title":"Effects of Enteral Nutrition on Stress Ulcer Hemorrage. Multicenter Randomized Controlled Trial","phase":"NA","overall_status":"UNKNOWN","enrollment_count":500,"lead_sponsor_name":"TC Erciyes University","has_results":false},{"nct_id":"NCT05900167","title":"Feeding Intolerance Risk Prediction Model in Patients With Enteral Nutrition Through Nasogastric Tube","phase":"","overall_status":"UNKNOWN","enrollment_count":442,"lead_sponsor_name":"Xiao Jie Chen","has_results":false},{"nct_id":"NCT03117348","title":"Gradual Versus Immediate Goal-dose Enteral Nutrition in Abdominal Surgery Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":411,"lead_sponsor_name":"Jinling Hospital, China","has_results":false},{"nct_id":"NCT01839617","title":"Study Comparing Early and Late Nutrition in Cancer Patients Undergoing Abdominal Surgery","phase":"NA","overall_status":"UNKNOWN","enrollment_count":335,"lead_sponsor_name":"Instituto do Cancer do Estado de São Paulo","has_results":false},{"nct_id":"NCT06161350","title":"The Multi-disciplinary Approach of Children With Feeding Difficulties and Tube Feeding in UZB Between 2000 and 2021","phase":"","overall_status":"UNKNOWN","enrollment_count":330,"lead_sponsor_name":"Universitair Ziekenhuis Brussel","has_results":false},{"nct_id":"NCT04466332","title":"Comparison of Two ECG Guided PICC Insertion Techniques","phase":"NA","overall_status":"COMPLETED","enrollment_count":320,"lead_sponsor_name":"University of Lausanne","has_results":false},{"nct_id":"NCT05627167","title":"Daytime Cyclic Enteral Nutrition Versus Standard Continuous Enteral Nutrition in the Intensive Care Unit: a Pilot Randomized Controlled Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":318,"lead_sponsor_name":"Centre Hospitalier le Mans","has_results":false},{"nct_id":"NCT04868318","title":"The Impact of Intervention With High-protein Enteral Formula in SICU.","phase":"NA","overall_status":"COMPLETED","enrollment_count":280,"lead_sponsor_name":"Tungs' Taichung Metroharbour Hospital","has_results":false},{"nct_id":"NCT04006730","title":"Analysis of the Pharmaceutical Validation of Picc Line Installation Requests at the Nîmes University Hospital","phase":"","overall_status":"COMPLETED","enrollment_count":277,"lead_sponsor_name":"Centre Hospitalier Universitaire de Nīmes","has_results":false},{"nct_id":"NCT03792100","title":"Efficacy & Safety of SmofKabiven Emulsion for Infusion vs Hospital Compounded \"All in One\" for Parenteral Nutrition","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":273,"lead_sponsor_name":"Fresenius Kabi","has_results":false},{"nct_id":"NCT01072721","title":"Non Invasive Study of the Hepatic Fibrosis in Paediatrics by the Method of Study of Pediatric Hepatic Fibrosis","phase":"NA","overall_status":"COMPLETED","enrollment_count":264,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT07176624","title":"The PRE-VAIL Study","phase":"NA","overall_status":"RECRUITING","enrollment_count":259,"lead_sponsor_name":"The First Hospital of Jilin University","has_results":false},{"nct_id":"NCT05519761","title":"A Retrospective, Observational, Multicenter Study to Evaluate the Safety and Performance of POLYSITE® and SEESITE® Implantable Ports","phase":"","overall_status":"UNKNOWN","enrollment_count":250,"lead_sponsor_name":"Perouse Medical","has_results":false},{"nct_id":"NCT06708689","title":"Overview of Botriomycoma in Children with a Central Line: Epidemiology, Risk Factors, Treatments","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":240,"lead_sponsor_name":"Hospices Civils de Lyon","has_results":false},{"nct_id":"NCT05788588","title":"A Phase Ⅲ Study of HR19006 Injection in Postsurgical Parenteral Nutrition","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":240,"lead_sponsor_name":"Fujian Shengdi Pharmaceutical Co., Ltd.","has_results":false},{"nct_id":"NCT04704895","title":"Comparing Early Enteral Nutrition Versus Parenteral Nutrition After Pancreaticoduodenectomy","phase":"NA","overall_status":"UNKNOWN","enrollment_count":210,"lead_sponsor_name":"Xian-Jun Yu","has_results":false},{"nct_id":"NCT03442361","title":"Olive Oil and Soybean 1 Oil Based Intravenous Lipid Emulsions, Liver Chemistry and Clinical Outcomes","phase":"","overall_status":"COMPLETED","enrollment_count":206,"lead_sponsor_name":"University of Calgary","has_results":false},{"nct_id":"NCT06905119","title":"Digital Transformation of Continuity of Care for Peripherally Inserted Central Catheters: SpadCare Experience","phase":"NA","overall_status":"RECRUITING","enrollment_count":201,"lead_sponsor_name":"Fundacion Miguel Servet","has_results":false},{"nct_id":"NCT06375148","title":"A Questionnaire Survey on Cognition of Enteral Nutrition Implementation in Patients Requiring Mechanical Ventilation in Prone Position","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":200,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT06737211","title":"Optimizing Postoperative Nutrition in Colorectal Surgery","phase":"NA","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"National and Kapodistrian University of Athens","has_results":false},{"nct_id":"NCT03401632","title":"Enteral Nutrition and Vasoactive Drugs","phase":"","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Hospital Severo Ochoa","has_results":false},{"nct_id":"NCT07337798","title":"Implementation of Clinical Nutrition Practice Guidelines in Surgical ICUs","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":200,"lead_sponsor_name":"Xuanwu Hospital, Beijing","has_results":false},{"nct_id":"NCT02998931","title":"Trial of Enteral Glutamine on Clinical Outcomes in Critically Ill Patients","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Shahid Beheshti University","has_results":false},{"nct_id":"NCT05879263","title":"\"Efficacy of Intermittent Enteral Nutrition Versus Continuous Administration in Intensive Care\"","phase":"NA","overall_status":"UNKNOWN","enrollment_count":190,"lead_sponsor_name":"Complejo Hospitalario Universitario de Albacete","has_results":false},{"nct_id":"NCT06510348","title":"Achieving nuTritional Target in criticAlly Ill patieNts With iMpairEd gastroiNtesTinal Dysfunction","phase":"NA","overall_status":"RECRUITING","enrollment_count":164,"lead_sponsor_name":"Romanian Society for Enteral and Parenteral Nutrition","has_results":false},{"nct_id":"NCT06237725","title":"Abdominal Massage in Enteral Nutrition Patients","phase":"NA","overall_status":"UNKNOWN","enrollment_count":164,"lead_sponsor_name":"TC Erciyes University","has_results":false},{"nct_id":"NCT07178626","title":"Association of Biomarkers and Gastric Antral Motility Index With Feeding Intolerance in Critically Ill Patients","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":160,"lead_sponsor_name":"The First Hospital of Jilin University","has_results":false},{"nct_id":"NCT03387358","title":"An Observational Study Examining Adverse Events and Effectiveness of the Nasal Bridle Securement Device in ICU Patients","phase":"","overall_status":"UNKNOWN","enrollment_count":160,"lead_sponsor_name":"University of British Columbia","has_results":false},{"nct_id":"NCT07115108","title":"Effectiveness of High-Energy Density Enteral Nutrition for Enhancing Physical Growth and Cognitive Brain Development in Infants With Congenital Heart Disease","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":160,"lead_sponsor_name":"Children's Hospital of Fudan University","has_results":false},{"nct_id":"NCT04199832","title":"To Compare the Effect of Different Nutritional Pathways on Improving Nutritional Status of Esophageal Cancer Patients Undergoing Chemoradiotherapy","phase":"","overall_status":"COMPLETED","enrollment_count":156,"lead_sponsor_name":"Tianjin Medical University Cancer Institute and Hospital","has_results":false},{"nct_id":"NCT06573632","title":"Perioperative TPN Improves Surgical Outcomes","phase":"","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Nepal Medical College and Teaching Hospital","has_results":false},{"nct_id":"NCT07307612","title":"High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants","phase":"PHASE1, PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":150,"lead_sponsor_name":"University of Alabama at Birmingham","has_results":false},{"nct_id":"NCT04977817","title":"Probiotics/TPN in the NICU","phase":"","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Pediatrix","has_results":false},{"nct_id":"NCT03693287","title":"Personalized vs Standardized PN for Preterm Infants >1250g","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"Ospedali Riuniti Ancona","has_results":false},{"nct_id":"NCT07270939","title":"Optimizing Enteral Nutrition Regimen for Critically Ill Patients","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":150,"lead_sponsor_name":"Hamad Medical Corporation","has_results":false},{"nct_id":"NCT03425435","title":"Quality of Care of Oncological Patients With HPN","phase":"","overall_status":"TERMINATED","enrollment_count":143,"lead_sponsor_name":"Fresenius Kabi","has_results":false},{"nct_id":"NCT06134674","title":"Early Versus Delayed Enteral Nutrition in Critically Ill Adults With COVID-19","phase":"","overall_status":"COMPLETED","enrollment_count":135,"lead_sponsor_name":"Ankara City Hospital Bilkent","has_results":false},{"nct_id":"NCT03730545","title":"Effect of Enteral Immunonutrition on Immune, Inflammatory Markers and Nutritional Status in Patients Undergoing Gastrectomy for Gastric Cancer","phase":"NA","overall_status":"COMPLETED","enrollment_count":124,"lead_sponsor_name":"West China Hospital","has_results":false},{"nct_id":"NCT06525753","title":"Weaning is Winning? (WeWin Study)","phase":"","overall_status":"RECRUITING","enrollment_count":120,"lead_sponsor_name":"The Hospital for Sick Children","has_results":false},{"nct_id":"NCT03652727","title":"FX vs. ECG Guidance for PICC Insertion","phase":"NA","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"Salah D. Qanadli","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}