{"disease":{"id":"dry-mouth","name":"dry mouth"},"drugs":{"marketed":[{"drug_id":"pilocarpine","indication_name":"Dry mouth due to radiotherapy","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Salagen","generic_name":"PILOCARPINE","company_name":"","drug_phase":"marketed","molecular_target":"Muscarinic acetylcholine receptor M4","drug_class":"Cholinergic Receptor Agonist","quality_score":45,"revenue":null,"mechanism":""},{"drug_id":"pilocarpine","indication_name":"Dry mouth in Sjogren's syndrome","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Salagen","generic_name":"PILOCARPINE","company_name":"","drug_phase":"marketed","molecular_target":"Muscarinic acetylcholine receptor M4","drug_class":"Cholinergic Receptor Agonist","quality_score":45,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":2,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05247333","title":"Implementation of a Minor Ailment Service in Community Pharmacy Practice","phase":"NA","overall_status":"COMPLETED","enrollment_count":20987,"lead_sponsor_name":"Universidad de Granada","has_results":false},{"nct_id":"NCT04632004","title":"Questionnaire Regarding the Effect of Wearing Face Masks on Oral Health","phase":"NA","overall_status":"COMPLETED","enrollment_count":3750,"lead_sponsor_name":"University of Göttingen","has_results":false},{"nct_id":"NCT03382730","title":"De-adoption of Oral Chlorhexidine Prophylaxis and Implementation of an Oral Care Bundle (CHORAL)","phase":"NA","overall_status":"COMPLETED","enrollment_count":3260,"lead_sponsor_name":"University of Toronto","has_results":false},{"nct_id":"NCT06555029","title":"Oral Health Intervention in Adult Primary Care","phase":"NA","overall_status":"RECRUITING","enrollment_count":929,"lead_sponsor_name":"Case Western Reserve University","has_results":false},{"nct_id":"NCT04189081","title":"Improvement of Dry Mouth Sufferers After Using an Experimental Dry Mouth Rinse Compared to a Water Control","phase":"NA","overall_status":"COMPLETED","enrollment_count":137,"lead_sponsor_name":"Procter and Gamble","has_results":true},{"nct_id":"NCT03649789","title":"Periodontal Outcomes After Sanative Therapy","phase":"","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"Brock University","has_results":false},{"nct_id":"NCT06900621","title":"Effects of Methods on Dry Mouth After Septoplasty Surgery","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":81,"lead_sponsor_name":"Ege University","has_results":false},{"nct_id":"NCT07084532","title":"Effects of Chewing Gum for Dry Mouth in Diabetes","phase":"NA","overall_status":"COMPLETED","enrollment_count":80,"lead_sponsor_name":"Çankırı Karatekin University","has_results":false},{"nct_id":"NCT03035825","title":"Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":73,"lead_sponsor_name":"Dental Innovation Foundation Under Royal Patronage","has_results":false},{"nct_id":"NCT06363955","title":"Assessing the Efficacy of a Carbamide Peroxide Mouthwash for Oral Wound Healing, Oral Hygiene and Xerostomia Relief","phase":"NA","overall_status":"COMPLETED","enrollment_count":54,"lead_sponsor_name":"National and Kapodistrian University of Athens","has_results":false},{"nct_id":"NCT06708195","title":"Efficacy of Transcutaneous Electrical Nerve Stimulation in Patients With Xerostomia (ETENX)","phase":"NA","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"Universidad de Murcia","has_results":false},{"nct_id":"NCT05640362","title":"Efficacy of Natural Enzymes Mouthwash: a Randomised Controlled Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":48,"lead_sponsor_name":"National University of Malaysia","has_results":false},{"nct_id":"NCT03295019","title":"\"Hyaluronan\" Formulation for Dry Mouth in Sleep Apnea Patients","phase":"NA","overall_status":"UNKNOWN","enrollment_count":45,"lead_sponsor_name":"You First Services","has_results":false},{"nct_id":"NCT04986501","title":"Clinical Evaluation of MucoPEG™ for Xerostomia","phase":"NA","overall_status":"COMPLETED","enrollment_count":42,"lead_sponsor_name":"SunBio, Inc.","has_results":true},{"nct_id":"NCT06763133","title":"The Effect of Cold Water Spray Application on Dry Mouth and Thirst Symptoms and Comfort of Patients After Endonasal Endoscopic Surgery After Admission to Intensive Care Unit","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"Saglik Bilimleri Universitesi","has_results":false},{"nct_id":"NCT04914208","title":"Effect of Wearing Face Masks on Salivary Parameters and Halitosis","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"University of Göttingen","has_results":false},{"nct_id":"NCT05871580","title":"Effect to the Photobiomodulation in the Burning Mouth Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"University of Santiago de Compostela","has_results":false},{"nct_id":"NCT03663231","title":"Duration of Effect of Biotene Spray in Patients With Dry Mouth","phase":"NA","overall_status":"COMPLETED","enrollment_count":37,"lead_sponsor_name":"University of Rochester","has_results":true},{"nct_id":"NCT06258603","title":"Oral Care of Intubated Intensive Care Patient","phase":"NA","overall_status":"COMPLETED","enrollment_count":35,"lead_sponsor_name":"Nigde Omer Halisdemir University","has_results":false},{"nct_id":"NCT04554342","title":"Testing of a Candy in Five Different Versions for the Additional Humidification of the Oral Cavity","phase":"NA","overall_status":"COMPLETED","enrollment_count":33,"lead_sponsor_name":"University Hospital, Basel, Switzerland","has_results":false},{"nct_id":"NCT03876197","title":"Mesenchymal Stem Cells for Radiation-induced Xerostomia","phase":"PHASE1, PHASE2","overall_status":"UNKNOWN","enrollment_count":30,"lead_sponsor_name":"Rigshospitalet, Denmark","has_results":false},{"nct_id":"NCT03281486","title":"\"Hyaluronan\" Formulation for Type 2 Diabetic Patients With Dry Mouth","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"You First Services","has_results":false},{"nct_id":"NCT06240806","title":"Efficacy of Manuka Honey Oral Rinse in Treatment of Xerostomia","phase":"NA","overall_status":"COMPLETED","enrollment_count":28,"lead_sponsor_name":"British University In Egypt","has_results":false},{"nct_id":"NCT04719091","title":"CLINICAL EVALUATION OF THE EFFICACY OF AN INTRA ORAL SPRAY FOR PATIENTS WITH XEROSTOMIA","phase":"NA","overall_status":"COMPLETED","enrollment_count":26,"lead_sponsor_name":"You First Services","has_results":false},{"nct_id":"NCT04152642","title":"A Pilot Study to Assess Dry Mouth Relief After Using an Experimental Mouth Rinse","phase":"NA","overall_status":"COMPLETED","enrollment_count":22,"lead_sponsor_name":"Procter and Gamble","has_results":true},{"nct_id":"NCT04195100","title":"Local Pilocarpine for Relieving Dry Mouth","phase":"EARLY_PHASE1","overall_status":"COMPLETED","enrollment_count":14,"lead_sponsor_name":"Maastricht University Medical Center","has_results":false},{"nct_id":"NCT03874572","title":"Allogeneic Mesenchymal Stem Cells for Radiation-induced Hyposalivation and Xerostomia/Dry Mouth","phase":"PHASE1","overall_status":"UNKNOWN","enrollment_count":10,"lead_sponsor_name":"Rigshospitalet, Denmark","has_results":false}],"total":27},"guidelines":[],"source":"Drug Landscape verified database"}