{"disease":{"id":"drug-reaction","name":"drug reaction"},"drugs":{"marketed":[{"drug_id":"prednisone","indication_name":"Drug hypersensitivity reactions","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Deltasone","generic_name":"prednisone","company_name":"Generic (originally Schering)","drug_phase":"marketed","molecular_target":"Annexin A1, Sodium/nucleoside cotransporter 1, Glucocorticoid receptor","drug_class":"Corticosteroid [EPC]","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"dexamethasone-phosphate","indication_name":"Drug hypersensitivity reactions","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Dexamethasone Sodium Phosphate","generic_name":"dexamethasone phosphate","company_name":"Merck & Co.","drug_phase":"marketed","molecular_target":"Androgen receptor, Glucocorticoid receptor, Mineralocorticoid receptor","drug_class":"Corticosteroid","quality_score":10,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":2,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04279470","title":"Chimeric Antigen Receptor T-cell and Cellular Therapies for the Treatment of cAncer or BLood Diseases: Evaluation of Reporting of Adverse Events","phase":"","overall_status":"COMPLETED","enrollment_count":100000,"lead_sponsor_name":"Groupe Hospitalier Pitie-Salpetriere","has_results":false},{"nct_id":"NCT04830241","title":"Neonatal Hypotonia Associated With in Utero Exposure to Antidepressant","phase":"","overall_status":"UNKNOWN","enrollment_count":10000,"lead_sponsor_name":"University Hospital, Caen","has_results":false},{"nct_id":"NCT03093818","title":"PREemptive Pharmacogenomic Testing for Preventing Adverse Drug REactions","phase":"NA","overall_status":"COMPLETED","enrollment_count":6950,"lead_sponsor_name":"J.J.Swen","has_results":false},{"nct_id":"NCT04568668","title":"Evaluating ActionADE in Reducing Adverse Drug Reactions","phase":"NA","overall_status":"UNKNOWN","enrollment_count":3600,"lead_sponsor_name":"University of British Columbia","has_results":false},{"nct_id":"NCT03775798","title":"Incidence of de Novo Hepatocellular Carcinoma After Antiviral Agents for HCV.","phase":"","overall_status":"UNKNOWN","enrollment_count":2200,"lead_sponsor_name":"Austral University, Argentina","has_results":false},{"nct_id":"NCT02097654","title":"Clinical Trial of a New Software ENgine for the Assessment & Optimization of Drug and Non-drug Therapy in Older peRsons","phase":"NA","overall_status":"COMPLETED","enrollment_count":1537,"lead_sponsor_name":"University College Cork","has_results":false},{"nct_id":"NCT05307718","title":"Pharmacogenomics in Prediction of Cardiovascular Drugs Adverse Reaction","phase":"","overall_status":"UNKNOWN","enrollment_count":1200,"lead_sponsor_name":"Clinical Hospital Centre Zagreb","has_results":false},{"nct_id":"NCT07497893","title":"FENOX Trial (Comparative Effectiveness of Fexuprazan Co-therapy in Patients Receiving Non-Vitamin K Antagonist Oral Anticoagulants)","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Ewha Womans University Mokdong Hospital","has_results":false},{"nct_id":"NCT04617340","title":"Effect of a trAnSitional Pharmacist Intervention in geRiatric Inpatients on Hospitals Visits After dischargE","phase":"NA","overall_status":"COMPLETED","enrollment_count":827,"lead_sponsor_name":"Universitaire Ziekenhuizen KU Leuven","has_results":false},{"nct_id":"NCT03123640","title":"Improving Drug Safety in Emergency Patients -a Randomized Controlled Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":806,"lead_sponsor_name":"Diakonhjemmet Hospital","has_results":false},{"nct_id":"NCT03338725","title":"Effect and Associated Factors of the Clinical Pharmacy Model in the Incidence of Medical Errors","phase":"NA","overall_status":"COMPLETED","enrollment_count":720,"lead_sponsor_name":"Universidad de Antioquia","has_results":false},{"nct_id":"NCT04740242","title":"Metabolic Alkalosis in Heart Failure","phase":"","overall_status":"COMPLETED","enrollment_count":672,"lead_sponsor_name":"Spanish Society of Internal Medicine","has_results":false},{"nct_id":"NCT06216002","title":"Incidence of Residual Neuromuscular Blockade in Fraility in OncoGynae Surgery","phase":"NA","overall_status":"RECRUITING","enrollment_count":622,"lead_sponsor_name":"Mahidol University","has_results":false},{"nct_id":"NCT03156348","title":"Impact of Clinical Pharmacist on Adverse Drug Events in Older Adults","phase":"NA","overall_status":"UNKNOWN","enrollment_count":611,"lead_sponsor_name":"University of Chile","has_results":false},{"nct_id":"NCT04196777","title":"Audit-and-feedback to Improve Antimicrobial-prescribing Among Urologists","phase":"NA","overall_status":"COMPLETED","enrollment_count":525,"lead_sponsor_name":"Iowa City Veterans Affairs Medical Center","has_results":true},{"nct_id":"NCT03659227","title":"Drug Reactions Sampling (COLLECTIONTOXIDERMIES)","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT03210077","title":"Romanian Entropy Clinical Study Network","phase":"","overall_status":"UNKNOWN","enrollment_count":500,"lead_sponsor_name":"Romanian Society of Anesthesia and Intensive Care","has_results":false},{"nct_id":"NCT06515080","title":"Predicting Outcomes Using Infra-red SEnsors, a Feasibility Study.","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":500,"lead_sponsor_name":"Uppsala University","has_results":false},{"nct_id":"NCT03369509","title":"Allergic Versus Non Allergic Hypersensitivity Drug Reaction (BdDAllergo)","phase":"","overall_status":"TERMINATED","enrollment_count":456,"lead_sponsor_name":"University Hospital, Grenoble","has_results":false},{"nct_id":"NCT04553107","title":"Reducing Costs by Deprescribing Medications","phase":"NA","overall_status":"COMPLETED","enrollment_count":419,"lead_sponsor_name":"The University of Texas Health Science Center, Houston","has_results":false},{"nct_id":"NCT04252326","title":"The Knowledge, Attitudes and Practices of Healthcare Workers on Drug Hypersensitivity Reactions in Children","phase":"NA","overall_status":"COMPLETED","enrollment_count":354,"lead_sponsor_name":"Saglik Bilimleri Universitesi","has_results":false},{"nct_id":"NCT05028361","title":"Simultaneous mRNA COVID-19 and IIV4 Vaccination Study","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":348,"lead_sponsor_name":"Duke University","has_results":true},{"nct_id":"NCT06427317","title":"Routinely Collected Clinical Data and Evaluation of Antimicrobial Target Attainment","phase":"","overall_status":"RECRUITING","enrollment_count":323,"lead_sponsor_name":"Imperial College London","has_results":false},{"nct_id":"NCT06406114","title":"Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Massachusetts General Hospital","has_results":false},{"nct_id":"NCT03566030","title":"Switching From Tenofovir Disoproxi Fumarate to Tenofovir Alafenamide in Chronic Hepatitis B Patients With Antiviral Resistance","phase":"","overall_status":"UNKNOWN","enrollment_count":300,"lead_sponsor_name":"Yonsei University","has_results":false},{"nct_id":"NCT05224804","title":"Pharmacists' Knowledge and Attitudes About ADRs Reporting and Pharmacovigilance Practice in Egyptian Hospitals","phase":"","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"Fayoum University","has_results":false},{"nct_id":"NCT06428162","title":"An Evaluation of Healthcare Providers' Adherence to Pharmacovigilance Practices in an African Community","phase":"","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"Deraya University","has_results":false},{"nct_id":"NCT04269486","title":"A Multicenter Observational Study on Safety of the Herbal Medicines at Inpatient Setting","phase":"","overall_status":"TERMINATED","enrollment_count":287,"lead_sponsor_name":"Korea Institute of Oriental Medicine","has_results":false},{"nct_id":"NCT06180876","title":"Effect of Remimazolam on Postoperative Delirium","phase":"NA","overall_status":"COMPLETED","enrollment_count":264,"lead_sponsor_name":"Zhihong LU","has_results":false},{"nct_id":"NCT05951660","title":"Sex, Psychopharmacology, and Diabetes","phase":"NA","overall_status":"RECRUITING","enrollment_count":256,"lead_sponsor_name":"Zealand University Hospital","has_results":false},{"nct_id":"NCT05670756","title":"Preoperative Survey to Evaluate Patient Allergy","phase":"","overall_status":"COMPLETED","enrollment_count":250,"lead_sponsor_name":"Nationwide Children's Hospital","has_results":true},{"nct_id":"NCT06630923","title":"PREVENTION OF WORSENING RENAL FUNCTION OF INTRAVENUS ALBUMIN IN HEART FAILURE PATIENTS","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":250,"lead_sponsor_name":"Democritus University of Thrace","has_results":false},{"nct_id":"NCT05341713","title":"Epileptic Seizure in Epilepsy Patients After SARS-CoV-2 Vaccination","phase":"","overall_status":"COMPLETED","enrollment_count":240,"lead_sponsor_name":"Xijing Hospital","has_results":false},{"nct_id":"NCT02482025","title":"The Secure Messaging for Medication Reconciliation Tool (SMMRT) Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":240,"lead_sponsor_name":"VA Office of Research and Development","has_results":true},{"nct_id":"NCT05099913","title":"The Role of Neuromodulators in Refractory Functional Dyspepsia","phase":"NA","overall_status":"UNKNOWN","enrollment_count":220,"lead_sponsor_name":"RenJi Hospital","has_results":false},{"nct_id":"NCT04580589","title":"DOAC ADRs Retrospective Study on Genetic Variations","phase":"","overall_status":"COMPLETED","enrollment_count":210,"lead_sponsor_name":"Cipherome, Inc.","has_results":false},{"nct_id":"NCT03943524","title":"Drug Interactions in Outpatients.","phase":"NA","overall_status":"SUSPENDED","enrollment_count":200,"lead_sponsor_name":"University of Buenos Aires","has_results":false},{"nct_id":"NCT06122948","title":"Effect of Intranasal Midazolam Versus Ketamine Midazolam Combination as a Premedication on the Occurrence of Postoperative Respiratory Adverse Events","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Kasr El Aini Hospital","has_results":false},{"nct_id":"NCT04101760","title":"Granulocyte Colony Stimulating Factor for for the Prevention of Febrile Neutropenia in Epithelial Ovarian Cancer","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Lei Li","has_results":false},{"nct_id":"NCT06929533","title":"Pharmacogenomics-Supported Psychotropic Prescribing Trial","phase":"NA","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"University of Manitoba","has_results":false},{"nct_id":"NCT04597593","title":"Association Between Genetic Variant Scores and DOACs (DARES2)","phase":"","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Cipherome, Inc.","has_results":false},{"nct_id":"NCT03354845","title":"Deprescribing of Symptomatic Medications in Rehabilitative or Subacute Care Patients","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Bright Vision Hospital","has_results":false},{"nct_id":"NCT03211208","title":"Assessing Antibiotic Induced Liver Injury for Stratification of Tuberculosis Patients","phase":"","overall_status":"COMPLETED","enrollment_count":194,"lead_sponsor_name":"University of Edinburgh","has_results":false},{"nct_id":"NCT07323043","title":"Comparison of Cough Response Between Tegilidine and Sufentanil as Pre-induction Agents in General Anesthesia","phase":"NA","overall_status":"RECRUITING","enrollment_count":190,"lead_sponsor_name":"The First People's Hospital of Lianyungang","has_results":false},{"nct_id":"NCT05902676","title":"The Effects Of Anticholinergic Burden On Daily Living Activities In Elderly Patients","phase":"","overall_status":"UNKNOWN","enrollment_count":180,"lead_sponsor_name":"Izmir Ataturk Training and Research Hospital","has_results":false},{"nct_id":"NCT07063706","title":"Pharmaceutical Care for Patients Using Capecitabine","phase":"NA","overall_status":"COMPLETED","enrollment_count":176,"lead_sponsor_name":"Faculdade de Farmácia","has_results":false},{"nct_id":"NCT06763081","title":"Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation","phase":"","overall_status":"RECRUITING","enrollment_count":160,"lead_sponsor_name":"University of Manitoba","has_results":false},{"nct_id":"NCT03501108","title":"Discontinuation of Long-term Medications in Older People Entering Nursing Home Care","phase":"NA","overall_status":"UNKNOWN","enrollment_count":160,"lead_sponsor_name":"University College Cork","has_results":false},{"nct_id":"NCT06272357","title":"The Use of Antiarrhythmic Drugs in Pediatrics","phase":"","overall_status":"UNKNOWN","enrollment_count":158,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT06498167","title":"Active Pharmacovigilance Study of the Medicine Rinvoq™ (Upadacitinib)","phase":"","overall_status":"RECRUITING","enrollment_count":150,"lead_sponsor_name":"Universidade do Porto","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}