{"disease":{"id":"drug-hypersensitivity","name":"drug hypersensitivity"},"drugs":{"marketed":[{"drug_id":"prednisone","indication_name":"Drug hypersensitivity reactions","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Deltasone","generic_name":"prednisone","company_name":"Generic (originally Schering)","drug_phase":"marketed","molecular_target":"Annexin A1, Sodium/nucleoside cotransporter 1, Glucocorticoid receptor","drug_class":"Corticosteroid [EPC]","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"dexamethasone-phosphate","indication_name":"Drug hypersensitivity reactions","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Dexamethasone Sodium Phosphate","generic_name":"dexamethasone phosphate","company_name":"Merck & Co.","drug_phase":"marketed","molecular_target":"Androgen receptor, Glucocorticoid receptor, Mineralocorticoid receptor","drug_class":"Corticosteroid","quality_score":10,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":2,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT02839551","title":"Optimal Doses for Drug Provocation Tests to Beta-lactams","phase":"NA","overall_status":"COMPLETED","enrollment_count":1252,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT04827602","title":"Drug Allergy Labels After Drug Allergy Investigation","phase":"","overall_status":"COMPLETED","enrollment_count":849,"lead_sponsor_name":"University Hospital, Gentofte, Copenhagen","has_results":false},{"nct_id":"NCT04421638","title":"Cephalosporin Hypersensitivity","phase":"","overall_status":"COMPLETED","enrollment_count":500,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT03771118","title":"Drug Provocation Test (DPT) to Paracetamol","phase":"","overall_status":"COMPLETED","enrollment_count":498,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT03369509","title":"Allergic Versus Non Allergic Hypersensitivity Drug Reaction (BdDAllergo)","phase":"","overall_status":"TERMINATED","enrollment_count":456,"lead_sponsor_name":"University Hospital, Grenoble","has_results":false},{"nct_id":"NCT03743220","title":"Drug Provocation Test (DPT) to Non Steroidal Anti-inflammatory Drugs (NSAID)","phase":"","overall_status":"COMPLETED","enrollment_count":311,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT06406114","title":"Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Massachusetts General Hospital","has_results":false},{"nct_id":"NCT06428162","title":"An Evaluation of Healthcare Providers' Adherence to Pharmacovigilance Practices in an African Community","phase":"","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"Deraya University","has_results":false},{"nct_id":"NCT02031120","title":"Management of Drug Hypersensitivity in Children","phase":"","overall_status":"TERMINATED","enrollment_count":207,"lead_sponsor_name":"University Hospital, Geneva","has_results":false},{"nct_id":"NCT07390370","title":"Establishment of a Registry for Immediate Drug Allergy","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":200,"lead_sponsor_name":"Yonsei University","has_results":false},{"nct_id":"NCT03158831","title":"Drug Challenges Without Prior Skin Testing","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":166,"lead_sponsor_name":"Montefiore Medical Center","has_results":false},{"nct_id":"NCT06523192","title":"Validation of the English Version of the Drug Hypersensitivity Quality of Life Questionnaire","phase":"","overall_status":"COMPLETED","enrollment_count":146,"lead_sponsor_name":"University Hospitals, Leicester","has_results":false},{"nct_id":"NCT02839811","title":"Medical Device for Drug Allergy Diagnosis","phase":"NA","overall_status":"COMPLETED","enrollment_count":145,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT07069439","title":"Turkish Version of the Parent-Reported Drug Hypersensitivity Quality of Life Questionnaire","phase":"","overall_status":"COMPLETED","enrollment_count":74,"lead_sponsor_name":"Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization","has_results":false},{"nct_id":"NCT05269082","title":"A Study to Assess the Hypersensitivity to TAK-880 Compared to Gammagard S/D in Blood of Children, Teenagers and Adults","phase":"","overall_status":"COMPLETED","enrollment_count":72,"lead_sponsor_name":"Takeda","has_results":false},{"nct_id":"NCT04988256","title":"Cyclosporine Vs Steroids in DRESS","phase":"EARLY_PHASE1","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":50,"lead_sponsor_name":"University of Southern California","has_results":false},{"nct_id":"NCT04610242","title":"Prediction of Rituximab Hypersensitivity and Desensitization Treatment","phase":"NA","overall_status":"UNKNOWN","enrollment_count":30,"lead_sponsor_name":"Peking Union Medical College Hospital","has_results":false}],"total":17},"guidelines":[],"source":"Drug Landscape verified database"}