{"disease":{"id":"down-syndrome-trisomy-21","name":"down syndrome trisomy 21"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT07334912","title":"AEF0217 in Participants With Down Syndrome","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":188,"lead_sponsor_name":"Aelis Farma","has_results":false},{"nct_id":"NCT07493096","title":"Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders","phase":"","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"Healing Hope International","has_results":false},{"nct_id":"NCT06911944","title":"Amyloid Lowering for Alzheimer's in Down's With Donanemab Investigation","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":60,"lead_sponsor_name":"Michael Rafii, MD, PhD","has_results":false},{"nct_id":"NCT07047963","title":"Neuropsychological Evaluation in Intellectual Disability (ENDI)","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":40,"lead_sponsor_name":"Central Hospital, Nancy, France","has_results":false},{"nct_id":"NCT06888570","title":"Relationship Between Eating Patterns, Body Composition and the Detection of Fatty Liver in Children and Adolescents With Trisomy 21: LiverTy Project","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":34,"lead_sponsor_name":"IMDEA Food","has_results":false},{"nct_id":"NCT07195253","title":"Oro-myofunctional Characteristics and Obstructive Sleep Apnea in Infants With Down Syndrome","phase":"","overall_status":"RECRUITING","enrollment_count":30,"lead_sponsor_name":"Hospices Civils de Lyon","has_results":false},{"nct_id":"NCT03551418","title":"Learning by Repetitive Viewing of Peer Modeling Patient Education Videos by Adults With Down Syndrome","phase":"NA","overall_status":"TERMINATED","enrollment_count":21,"lead_sponsor_name":"Wake Forest University Health Sciences","has_results":false},{"nct_id":"NCT06783725","title":"Sleep Intervention and Quality of Life in Down Syndrome","phase":"NA","overall_status":"RECRUITING","enrollment_count":20,"lead_sponsor_name":"University of Alabama at Birmingham","has_results":false},{"nct_id":"NCT05231798","title":"Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition","phase":"PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":20,"lead_sponsor_name":"Vanderbilt University Medical Center","has_results":false},{"nct_id":"NCT05307523","title":"Use of Partial Body Weight Support Play Environment to Encourage Mobility and Exploration in Infants With Down Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":17,"lead_sponsor_name":"University of Washington","has_results":true},{"nct_id":"NCT03653143","title":"JASPER Intervention in Down Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":12,"lead_sponsor_name":"Boston Children's Hospital","has_results":false},{"nct_id":"NCT03687619","title":"Cognitive Orientation to Daily Occupational Performance and Conductive Education Approaches on Down Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":12,"lead_sponsor_name":"Eastern Mediterranean University","has_results":false}],"total":12},"guidelines":[],"source":"Drug Landscape verified database"}