{"disease":{"id":"disorder-major-depressive","name":"disorder major depressive"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06641726","title":"Creating a Global Research Database That Connects Genetic Information and Long-term Health Data to Improve Personalized Treatment for People With Serious Mental Illness","phase":"","overall_status":"RECRUITING","enrollment_count":50000,"lead_sponsor_name":"Akrivia Health","has_results":false},{"nct_id":"NCT07281729","title":"Investigation on Risk Factors for Suicide Among Chinese Patients With Mood Disorders","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":25000,"lead_sponsor_name":"Shanghai Mental Health Center","has_results":false},{"nct_id":"NCT03716869","title":"Universal vs. Targeted School Screening for Adolescent Major Depressive Disorder","phase":"NA","overall_status":"COMPLETED","enrollment_count":12909,"lead_sponsor_name":"Milton S. Hershey Medical Center","has_results":true},{"nct_id":"NCT00018057","title":"Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":3500,"lead_sponsor_name":"National Institute of Mental Health (NIMH)","has_results":false},{"nct_id":"NCT05603104","title":"Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":1254,"lead_sponsor_name":"Dr. Inge Winter","has_results":false},{"nct_id":"NCT04031469","title":"A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease","phase":"","overall_status":"SUSPENDED","enrollment_count":1000,"lead_sponsor_name":"ProgenaBiome","has_results":false},{"nct_id":"NCT05547711","title":"Prediction and Validation of Unipolar Depression With Psychosocial-somatic Markers in a Naturalistic Cohort Recruited in an Outpatient Setting","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":950,"lead_sponsor_name":"Julia Eder","has_results":false},{"nct_id":"NCT06789822","title":"Detection Algorithm for Recurrence or Relapse of Depression Thanks to a Smartwach","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":800,"lead_sponsor_name":"Dalia Care","has_results":false},{"nct_id":"NCT07031817","title":"Validation of a Composite Medical Device Using a Blood Biomarker-based Algorithm and MDQ for the Diagnosis of Bipolar Disorder","phase":"NA","overall_status":"RECRUITING","enrollment_count":623,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT04999553","title":"Left vs. Right Non-Inferiority Trial","phase":"NA","overall_status":"UNKNOWN","enrollment_count":420,"lead_sponsor_name":"University of British Columbia","has_results":false},{"nct_id":"NCT05603819","title":"Clinical Validation Study for EDIT-B Test: an Aid for Differential Diagnosis of Bipolar Disorder, Based on RNA Editing Blood Biomarkers","phase":"","overall_status":"COMPLETED","enrollment_count":418,"lead_sponsor_name":"Alcediag","has_results":false},{"nct_id":"NCT03113968","title":"ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD)","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":403,"lead_sponsor_name":"Bo Hu","has_results":true},{"nct_id":"NCT07444463","title":"Brain Network Mechanisms of Cognitive Impairments in Major Psychiatric Disorders and Their Clinical Applications","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":400,"lead_sponsor_name":"Central South University","has_results":false},{"nct_id":"NCT03481049","title":"Individualizing Incentives for Alcohol in the Severely Mentally Ill","phase":"NA","overall_status":"COMPLETED","enrollment_count":392,"lead_sponsor_name":"Washington State University","has_results":true},{"nct_id":"NCT05030272","title":"Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings","phase":"NA","overall_status":"COMPLETED","enrollment_count":343,"lead_sponsor_name":"Wake Forest University Health Sciences","has_results":false},{"nct_id":"NCT05717439","title":"Feasibility and ML Training Investigation of the Senseye DT for Diagnosis of Adults with PTSD","phase":"","overall_status":"COMPLETED","enrollment_count":338,"lead_sponsor_name":"Senseye, Inc.","has_results":false},{"nct_id":"NCT06793397","title":"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":330,"lead_sponsor_name":"Cybin IRL Limited","has_results":false},{"nct_id":"NCT04068467","title":"Evaluation of mHealth for Serious Mental Illness","phase":"NA","overall_status":"COMPLETED","enrollment_count":315,"lead_sponsor_name":"University of Washington","has_results":false},{"nct_id":"NCT03615794","title":"A Study of Pregnant and Postpartum Women With and Without Mood Disorders","phase":"","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"Johns Hopkins University","has_results":false},{"nct_id":"NCT06662526","title":"Lithium for Prevention of Cognitive Declining in Mood Illnesses","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":250,"lead_sponsor_name":"University of Chile","has_results":false},{"nct_id":"NCT03735576","title":"Cognitive Behavioural Therapy for the Treatment of Late Life Depression","phase":"NA","overall_status":"COMPLETED","enrollment_count":250,"lead_sponsor_name":"University of Cologne","has_results":false},{"nct_id":"NCT04260750","title":"ICBT for Depression - A Factorial Investigation of Kinds of Therapist Support and Self-/Expert-selected Content","phase":"NA","overall_status":"COMPLETED","enrollment_count":246,"lead_sponsor_name":"Linkoeping University","has_results":false},{"nct_id":"NCT00025974","title":"Brain Chemical Receptor Effects in Patients With Panic Disorder and Post-Traumatic Stress Disorder","phase":"","overall_status":"COMPLETED","enrollment_count":230,"lead_sponsor_name":"National Institute of Mental Health (NIMH)","has_results":false},{"nct_id":"NCT06152705","title":"Comparing the Efficacy of fMRI-Guided vs. Standard iTBS in Treating Depression","phase":"NA","overall_status":"RECRUITING","enrollment_count":210,"lead_sponsor_name":"The Royal Ottawa Mental Health Centre","has_results":false},{"nct_id":"NCT05811897","title":"RESILIENT : A Self-Managed Online Platform for Victims of Sexual Assault","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":204,"lead_sponsor_name":"Laval University","has_results":false},{"nct_id":"NCT06646692","title":"Mindful Self-Compassion to Address PTSD and Substance Use in Unhoused Women","phase":"NA","overall_status":"RECRUITING","enrollment_count":202,"lead_sponsor_name":"University of California, Los Angeles","has_results":false},{"nct_id":"NCT06724666","title":"Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and Depression","phase":"NA","overall_status":"RECRUITING","enrollment_count":198,"lead_sponsor_name":"Babes-Bolyai University","has_results":false},{"nct_id":"NCT05530642","title":"An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Personnel","phase":"NA","overall_status":"UNKNOWN","enrollment_count":192,"lead_sponsor_name":"University of Regina","has_results":false},{"nct_id":"NCT05725785","title":"Technology-Assisted Implementation of a Mobile Health Program for Serious Mental Illness","phase":"NA","overall_status":"COMPLETED","enrollment_count":191,"lead_sponsor_name":"University of Washington","has_results":false},{"nct_id":"NCT04469322","title":"Pharmacogenetic Implementation Trial in Veterans With Treatment Refractory Depression","phase":"NA","overall_status":"COMPLETED","enrollment_count":182,"lead_sponsor_name":"San Diego Veterans Healthcare System","has_results":false},{"nct_id":"NCT06740331","title":"Social Cognition, Memory, and Executive Functions in Bipolar Disorder and Major Depressive Disorder","phase":"NA","overall_status":"RECRUITING","enrollment_count":180,"lead_sponsor_name":"CHU de Reims","has_results":false},{"nct_id":"NCT03329287","title":"Simplified Cognitive Behavioral Therapy for Generalized Anxiety Disorder and Depression","phase":"NA","overall_status":"UNKNOWN","enrollment_count":180,"lead_sponsor_name":"Shanghai Mental Health Center","has_results":false},{"nct_id":"NCT04675593","title":"Using mHealth to Improve Adherence and Reduce Blood Pressure in Individuals With Hypertension and Mood Disorders","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":176,"lead_sponsor_name":"Case Western Reserve University","has_results":false},{"nct_id":"NCT00071123","title":"Evaluating Brain Responses to Facial Expressions in Major Depressive Disorder","phase":"","overall_status":"COMPLETED","enrollment_count":172,"lead_sponsor_name":"National Institute of Mental Health (NIMH)","has_results":false},{"nct_id":"NCT07061600","title":"Enhancing Depression Literacy and Reducing Stigma in Adolescents Through Social Media","phase":"NA","overall_status":"COMPLETED","enrollment_count":170,"lead_sponsor_name":"Ludwig-Maximilians - University of Munich","has_results":false},{"nct_id":"NCT03406052","title":"Smartphone-enabled Health Coaching Intervention for Youth Diagnosed With Major Depressive Disorders","phase":"NA","overall_status":"SUSPENDED","enrollment_count":168,"lead_sponsor_name":"York University","has_results":false},{"nct_id":"NCT06402422","title":"Vulnerability Markers for Depression","phase":"","overall_status":"COMPLETED","enrollment_count":166,"lead_sponsor_name":"The Hong Kong Polytechnic University","has_results":false},{"nct_id":"NCT06331572","title":"Exploring Blood Plasma Metabolomics: Unraveling the Metabolic Landscape in Treatment-Resistant Adolescent Depression","phase":"","overall_status":"COMPLETED","enrollment_count":162,"lead_sponsor_name":"First Affiliated Hospital of Chongqing Medical University","has_results":false},{"nct_id":"NCT05701345","title":"Study of Virtual Reality-based Medical Device for Patients with Depressive Disorder","phase":"NA","overall_status":"COMPLETED","enrollment_count":162,"lead_sponsor_name":"Omni C&S","has_results":false},{"nct_id":"NCT07506070","title":"Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":160,"lead_sponsor_name":"The Royal Ottawa Mental Health Centre","has_results":false},{"nct_id":"NCT07404085","title":"Epigenetic Enhancement of Cognitive Training in Aging Mood Disorder Populations","phase":"NA","overall_status":"RECRUITING","enrollment_count":160,"lead_sponsor_name":"Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital","has_results":false},{"nct_id":"NCT02815813","title":"Lifestyle Intervention for Young Adults With Serious Mental Illness","phase":"NA","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Dartmouth-Hitchcock Medical Center","has_results":true},{"nct_id":"NCT05423405","title":"The Efficacy of Acupressure Therapy on Patient With Depression","phase":"NA","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"University Psychiatric Clinics Basel","has_results":false},{"nct_id":"NCT05135897","title":"The Neurobiological Fundaments of Depression and Its Relief Through Neurostimulation Treatments","phase":"","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"Haukeland University Hospital","has_results":false},{"nct_id":"NCT01483391","title":"Early Intervention for Youth at Risk for Bipolar Disorder","phase":"NA","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"University of California, Los Angeles","has_results":false},{"nct_id":"NCT07234851","title":"Understanding Mechanisms of Synaptic Degeneration Underlying Clinical Symptoms in Patients With MDs and NDs.","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":150,"lead_sponsor_name":"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau","has_results":false},{"nct_id":"NCT06080646","title":"Reward Processing and Depressive Subtypes: Identifying Neural Biotypes","phase":"","overall_status":"RECRUITING","enrollment_count":150,"lead_sponsor_name":"San Francisco Veterans Affairs Medical Center","has_results":false},{"nct_id":"NCT06093906","title":"Positive Processes and Transition to Health (PATH)","phase":"NA","overall_status":"RECRUITING","enrollment_count":135,"lead_sponsor_name":"Case Western Reserve University","has_results":false},{"nct_id":"NCT04358900","title":"Unobtrusive Monitoring of Affective Symptoms and Cognition Using Keyboard Dynamics (UnMASCK)","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":132,"lead_sponsor_name":"University of Illinois at Chicago","has_results":false},{"nct_id":"NCT05686408","title":"Study to Evaluate TNX-601 ER Monotherapy Versus Placebo in Patients With Major Depressive Disorder (MDD)","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":132,"lead_sponsor_name":"Tonix Pharmaceuticals, Inc.","has_results":true}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}