{"disease":{"id":"diastolic-dysfunction","name":"diastolic dysfunction"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03138109","title":"Analysis of Incidence and Risk Factors of Severe Cardiovascular Events in Patients With Diastolic Dysfunction","phase":"","overall_status":"COMPLETED","enrollment_count":4347,"lead_sponsor_name":"Yan Zhou, MD","has_results":false},{"nct_id":"NCT03972644","title":"Danish National Randomized Study on Early Aortic Valve Replacement in Patients With Asymptomatic Severe Aortic Stenosis","phase":"NA","overall_status":"RECRUITING","enrollment_count":1700,"lead_sponsor_name":"Odense University Hospital","has_results":false},{"nct_id":"NCT05647577","title":"The Relationship Between Inflammatory ARTritis and CArdiac DIseAse","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":1285,"lead_sponsor_name":"University Hospital, Gentofte, Copenhagen","has_results":false},{"nct_id":"NCT05058833","title":"Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function","phase":"","overall_status":"COMPLETED","enrollment_count":800,"lead_sponsor_name":"Samsung Medical Center","has_results":false},{"nct_id":"NCT06029192","title":"Diastolic Function in Myotonic Dystrophy Type 1","phase":"","overall_status":"UNKNOWN","enrollment_count":500,"lead_sponsor_name":"Centre d'Investigation Clinique et Technologique 805","has_results":false},{"nct_id":"NCT04505449","title":"Invasive Left Heart Catheterization Registry","phase":"","overall_status":"COMPLETED","enrollment_count":404,"lead_sponsor_name":"Samsung Medical Center","has_results":false},{"nct_id":"NCT03962166","title":"Characterizing Patients With POAF in Relation to Cardiac Surgery by wavECG and TTE","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":353,"lead_sponsor_name":"Helena DOMINGUEZ","has_results":false},{"nct_id":"NCT03198611","title":"Reversibility of Diastolic Disfunction in Septic Shock","phase":"","overall_status":"UNKNOWN","enrollment_count":350,"lead_sponsor_name":"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau","has_results":false},{"nct_id":"NCT04699565","title":"Characterization of Patients With Post-ischemic Left Ventricular Dysfunction","phase":"","overall_status":"COMPLETED","enrollment_count":303,"lead_sponsor_name":"IRCCS San Raffaele","has_results":false},{"nct_id":"NCT04584203","title":"Diastolic dYsfunctioN AssessMent in critICally Ill Patients","phase":"","overall_status":"UNKNOWN","enrollment_count":297,"lead_sponsor_name":"Humanitas Clinical and Research Center","has_results":false},{"nct_id":"NCT04687111","title":"Personalised Prospective Comparison of ARni With ArB in Patients With Natriuretic Peptide eLEvation","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":250,"lead_sponsor_name":"Mark Ledwidge","has_results":false},{"nct_id":"NCT03522194","title":"Left Ventricular Diastolic Function During Anesthesia Induction","phase":"","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Universitätsklinikum Hamburg-Eppendorf","has_results":false},{"nct_id":"NCT05408559","title":"Prevention of Age-associated Cardiac and Vascular Dysfunction Using Avmacol ES","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"Texas Tech University Health Sciences Center","has_results":false},{"nct_id":"NCT02860156","title":"Characterizing HIV-related Diastolic Dysfunction","phase":"","overall_status":"COMPLETED","enrollment_count":195,"lead_sponsor_name":"Duke University","has_results":false},{"nct_id":"NCT02294292","title":"Therapeutic Approach to Diastolic Dysfunction in Chronic Liver Disease Patients and Its Impact on Morbidity and Mortality","phase":"NA","overall_status":"COMPLETED","enrollment_count":189,"lead_sponsor_name":"Institute of Liver and Biliary Sciences, India","has_results":false},{"nct_id":"NCT03209141","title":"Screening of Diastolic Dysfunction With Impedance Cardiography in Hypertensive Patients","phase":"","overall_status":"COMPLETED","enrollment_count":154,"lead_sponsor_name":"Centro Hospitalar de Lisboa Central","has_results":false},{"nct_id":"NCT02932436","title":"Effects of Empagliflozin on Left Ventricular Diastolic Function Compared to Usual Care in Type 2 Diabetics","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":144,"lead_sponsor_name":"Johannes Gutenberg University Mainz","has_results":false},{"nct_id":"NCT06341101","title":"Timely Recovery After Subclinical Heart Failure","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":130,"lead_sponsor_name":"Academisch Ziekenhuis Maastricht","has_results":false},{"nct_id":"NCT03635801","title":"The MyoVista Angiography Angioplasty Percutaneous Coronary Intervention Trial","phase":"","overall_status":"TERMINATED","enrollment_count":126,"lead_sponsor_name":"Royal Cornwall Hospitals Trust","has_results":false},{"nct_id":"NCT04721314","title":"Personalized Pacing: A New Paradigm for Patients With Diastolic Dysfunction or Heart Failure With Preserved Ejection Fraction","phase":"NA","overall_status":"COMPLETED","enrollment_count":123,"lead_sponsor_name":"University of Vermont","has_results":false},{"nct_id":"NCT04177225","title":"Effect of Diastolic Dysfunction on Dynamic Cardiac Monitors","phase":"","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"University of California, Davis","has_results":false},{"nct_id":"NCT04128735","title":"Diastolic Dysfunction in Morbidly Obese Patients Undergo Bariatric Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":116,"lead_sponsor_name":"Mahidol University","has_results":false},{"nct_id":"NCT04154878","title":"2 New Measurements Used to Describe the Filling Phase of the Left Ventricle (LV).","phase":"","overall_status":"COMPLETED","enrollment_count":111,"lead_sponsor_name":"AdventHealth","has_results":false},{"nct_id":"NCT05699915","title":"Extensive CArdioVAscular Characterization and Follow-up of Patients Receiving Immune Checkpoint Inhibitors","phase":"NA","overall_status":"TERMINATED","enrollment_count":105,"lead_sponsor_name":"Algemeen Ziekenhuis Maria Middelares","has_results":false},{"nct_id":"NCT03349593","title":"Prevalence of Hypovolemia and Heart Failure in Non-cardiac Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"Umeå University","has_results":false},{"nct_id":"NCT03177408","title":"Impact of HMGB1 on Diastolic Dysfunction in Hypertensive Patients","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Jing Li","has_results":false},{"nct_id":"NCT05608603","title":"Diagnostics of Coronavirus Disease 2019 Cardiovascular Complications","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"I.M. Sechenov First Moscow State Medical University","has_results":false},{"nct_id":"NCT03196687","title":"Frequency of Asymptomatic Left Ventricular Diastolic Dysfunction in Diabetes Mellitus Type 2","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT04114474","title":"Pre-operative Focused Transthoracic Echocardiography for Prediction of Post-operative Cardiac Complications","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"South Egypt Cancer Institute","has_results":false},{"nct_id":"NCT05552521","title":"Diastolic Dysfunction in Septic Shock and Cardiomyopathy Genetic Variants","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"Hospital Garcia de Orta","has_results":false},{"nct_id":"NCT03110614","title":"Diastolic Dysfunction and Pauci-inflammatory Acute Exacerbations of COPD","phase":"","overall_status":"COMPLETED","enrollment_count":94,"lead_sponsor_name":"University of Alabama at Birmingham","has_results":false},{"nct_id":"NCT03768752","title":"Diastolic Dysfunction and Interstitial Lung Edema in Septic Patients","phase":"","overall_status":"COMPLETED","enrollment_count":83,"lead_sponsor_name":"Universitätsklinikum Hamburg-Eppendorf","has_results":false},{"nct_id":"NCT05175066","title":"Bisoprolol Administration to Prevent Anthracycline-induced Cardiotoxicity","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":80,"lead_sponsor_name":"Shahid Beheshti University of Medical Sciences","has_results":false},{"nct_id":"NCT05847244","title":"The Effect of Addition of Metformin In Obese Non- Diabetic Patients With Heart Failure With Preserved Ejection Fraction","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":80,"lead_sponsor_name":"Sara ElAdawy","has_results":false},{"nct_id":"NCT03744975","title":"PDD in Type 2 Diabetes w/wo Diastolic Dysfunction","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":72,"lead_sponsor_name":"Mayo Clinic","has_results":false},{"nct_id":"NCT03495999","title":"Hyperuricemia and Left Ventricular Diastolic Function","phase":"","overall_status":"TERMINATED","enrollment_count":67,"lead_sponsor_name":"National Defense Medical Center, Taiwan","has_results":false},{"nct_id":"NCT06945913","title":"Effect of Swimming Exercise on Diastolic Dysfunction","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":60,"lead_sponsor_name":"Uşak University","has_results":false},{"nct_id":"NCT04025996","title":"REWARD: Using the REtina as a Window To Detect Cardiac microvasculAR Dysfunction In Diabetes Mellitus","phase":"","overall_status":"UNKNOWN","enrollment_count":60,"lead_sponsor_name":"National Heart Centre Singapore","has_results":false},{"nct_id":"NCT07331233","title":"A Cross-sectional Study on the Impact of Shift Work on Diastolic Dysfunction in Healthcare Workers","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":60,"lead_sponsor_name":"National Taiwan University Hospital","has_results":false},{"nct_id":"NCT05988346","title":"Ghrelin and Diastolic Heart Function","phase":"","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"University of Campania Luigi Vanvitelli","has_results":false},{"nct_id":"NCT06129448","title":"Tumor Necrosis Factor-alpha Levels and Cardiac Functions in Type 1 Diabetes Mellitus","phase":"","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Sirnak State Hospital","has_results":false},{"nct_id":"NCT04149990","title":"Angiotensin-Neprilysin Inhibition in Diastolic Dysfunction After AMI","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":51,"lead_sponsor_name":"Jacob Moller","has_results":false},{"nct_id":"NCT04703387","title":"Left Ventricular Diastolic Dysfunction as a Predictor of Weaning Failure From Mechanical Ventilation","phase":"","overall_status":"COMPLETED","enrollment_count":48,"lead_sponsor_name":"Tanta University","has_results":false},{"nct_id":"NCT03576261","title":"Heart Failure and Hemodynamic Stability During Anesthesia Induction","phase":"NA","overall_status":"COMPLETED","enrollment_count":44,"lead_sponsor_name":"Umeå University","has_results":false},{"nct_id":"NCT05379608","title":"Intermittent Hypoxic-hyperoxic Training in Patients With Cardiovascular Pathology After COVID-19 Infection.","phase":"NA","overall_status":"COMPLETED","enrollment_count":43,"lead_sponsor_name":"I.M. Sechenov First Moscow State Medical University","has_results":false},{"nct_id":"NCT06584734","title":"Effect of Intradialytic Exercise on Left Ventricular Diastolic Function in Hemodialysis Patients","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":41,"lead_sponsor_name":"Instituto Nacional de Cardiologia Ignacio Chavez","has_results":false},{"nct_id":"NCT03249532","title":"Effect of Dialysis Techniques on Blood Pressure and Cardiac Function During Dialysis","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"Amsterdam UMC, location VUmc","has_results":false},{"nct_id":"NCT05438030","title":"Diastolic Function Assessment With Cardiac Magnetic Resonance Imaging","phase":"NA","overall_status":"UNKNOWN","enrollment_count":37,"lead_sponsor_name":"Imperial College London","has_results":false},{"nct_id":"NCT04916184","title":"Aerobic Versus Combined Exercise and Diastolic Dysfunction","phase":"NA","overall_status":"COMPLETED","enrollment_count":32,"lead_sponsor_name":"Evangelismos Hospital","has_results":false},{"nct_id":"NCT06131008","title":"Diastology-Guided Management of Decompensated Heart Failure","phase":"NA","overall_status":"UNKNOWN","enrollment_count":30,"lead_sponsor_name":"McMaster University","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}