{"disease":{"id":"dental-plaque","name":"Dental plaque","therapeutic_area":"","data":{},"enrichment_level":0,"last_enriched_at":null,"visit_count":0,"created_at":"2026-04-19T18:31:21.150Z","updated_at":"2026-04-19T18:39:44.960Z","meddra_pt":null,"meddra_code":null,"icd10_codes":null,"synonyms":[],"prevalence_global":null,"prevalence_us":null,"marketed_drug_count":1,"pipeline_drug_count":0,"trial_count":6},"drugs":{"marketed":[{"drug_id":"delmopinol","indication_name":"Dental plaque","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Decapinol","generic_name":"DELMOPINOL","company_name":"","drug_phase":"phase_2","molecular_target":"","drug_class":"delmopinol","quality_score":null,"revenue":null,"mechanism":"Decapinol works by preventing the adhesion of bacteria to tooth surfaces."}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06523712","title":"A Scalable, Teacher-delivered, School-based Oral Health Intervention for Pakistani Lower Secondary Schoolchildren","phase":"NA","overall_status":"COMPLETED","enrollment_count":4055,"lead_sponsor_name":"Universiti Putra Malaysia","has_results":false},{"nct_id":"NCT05594004","title":"A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health","phase":"","overall_status":"COMPLETED","enrollment_count":2929,"lead_sponsor_name":"Procter and Gamble","has_results":false},{"nct_id":"NCT04006483","title":"Meta-analysis of Stannous Fluoride and the Effects on Dental Plaque","phase":"","overall_status":"COMPLETED","enrollment_count":2359,"lead_sponsor_name":"Procter and Gamble","has_results":false},{"nct_id":"NCT04001296","title":"The Impact of a 21day School Brushing Intervention on the Knowledge, Behaviour and Oral Health of School Children","phase":"NA","overall_status":"COMPLETED","enrollment_count":2020,"lead_sponsor_name":"Unilever R&D","has_results":false},{"nct_id":"NCT03703245","title":"Pooled Analysis of Clinical Data From Six GSK Studies to Investigate the Efficacy of a Dentifrice Containing 67% Weight by Weight (w/w) Sodium Bicarbonate on Gingivitis and Plaque Accumulation","phase":"","overall_status":"COMPLETED","enrollment_count":1601,"lead_sponsor_name":"GlaxoSmithKline","has_results":false},{"nct_id":"NCT05779332","title":"Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization","phase":"","overall_status":"COMPLETED","enrollment_count":655,"lead_sponsor_name":"Recep Tayyip Erdogan University Training and Research Hospital","has_results":false},{"nct_id":"NCT04339647","title":"Effect of the SIMS Programme on Preschool Children's Oral Hygiene Level","phase":"NA","overall_status":"COMPLETED","enrollment_count":653,"lead_sponsor_name":"University of Malaya","has_results":false},{"nct_id":"NCT06081868","title":"RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda","phase":"NA","overall_status":"SUSPENDED","enrollment_count":610,"lead_sponsor_name":"University of Bern","has_results":false},{"nct_id":"NCT03390452","title":"Mobile Phone Messaging To Improve Oral Hygiene Among Primary School Children in Pakistan","phase":"NA","overall_status":"COMPLETED","enrollment_count":362,"lead_sponsor_name":"Health Services Academy, Islamabad, Pakistan","has_results":false},{"nct_id":"NCT07205588","title":"Assessment of Dental Pathologies Using Digital Tools","phase":"","overall_status":"RECRUITING","enrollment_count":350,"lead_sponsor_name":"Recherche Clinique en Odontologie (ReCOL)","has_results":false},{"nct_id":"NCT04254770","title":"At-Home Care for Subjects With Periodontitis","phase":"NA","overall_status":"COMPLETED","enrollment_count":346,"lead_sponsor_name":"Philips Clinical & Medical Affairs Global","has_results":false},{"nct_id":"NCT06760104","title":"Comparative Accuracy of AI Models and Clinical Assessment for Dental Plaque Detection in Children","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":323,"lead_sponsor_name":"Naema Ahmed","has_results":false},{"nct_id":"NCT05304247","title":"Prevalence and Risk Factors of Black Tooth Stains","phase":"","overall_status":"UNKNOWN","enrollment_count":320,"lead_sponsor_name":"Mennatallah Hesham Elsayed Mohamed Ali","has_results":false},{"nct_id":"NCT03988374","title":"Clinical Efficacy Evaluation of Three Dentifrices","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":319,"lead_sponsor_name":"Church & Dwight Company, Inc.","has_results":true},{"nct_id":"NCT06932211","title":"A Study to Measure the Effect of a Toothpaste Containing Proteins and Enzymes and a Fluoride Toothpaste on Gingival Health","phase":"NA","overall_status":"COMPLETED","enrollment_count":251,"lead_sponsor_name":"Unilever R&D","has_results":false},{"nct_id":"NCT04003493","title":"LifE Style, Nutrition and Oral Health in Care Givers (LENTO)","phase":"NA","overall_status":"COMPLETED","enrollment_count":250,"lead_sponsor_name":"University of Eastern Finland","has_results":false},{"nct_id":"NCT03576326","title":"BEhavioral EConomics for Oral Health iNnovation Trial","phase":"NA","overall_status":"COMPLETED","enrollment_count":244,"lead_sponsor_name":"University of California, San Francisco","has_results":true},{"nct_id":"NCT07029438","title":"Comparative Efficacy of Floss and Essential Oil/CPC+Zn Mouthwashes in Reducing Dental Plaque and Gingivitis","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":228,"lead_sponsor_name":"Colgate Palmolive","has_results":false},{"nct_id":"NCT06660069","title":"A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation","phase":"NA","overall_status":"COMPLETED","enrollment_count":199,"lead_sponsor_name":"HALEON","has_results":true},{"nct_id":"NCT05654662","title":"A Clinical Study Investigating the Effects of a Dentifrice Containing 67% Sodium Bicarbonate When Used Twice Daily for 12 Weeks on Gingivitis Treatment and Plaque Removal","phase":"NA","overall_status":"COMPLETED","enrollment_count":197,"lead_sponsor_name":"HALEON","has_results":true},{"nct_id":"NCT07526805","title":"Digital Manufacturing and Periodontal Performance of CAD/CAM-Customized Orthodontic Molar Bands Compared With Standard Stainless-Steel Bands","phase":"NA","overall_status":"COMPLETED","enrollment_count":180,"lead_sponsor_name":"Dimitrie Cantemir University","has_results":false},{"nct_id":"NCT07125560","title":"Effectiveness MyBRUSH Module in Improving Knowledge, Attitude, and Behaviour on Toothpaste Use and Toothbrushing Among 12-Year-Old Children","phase":"NA","overall_status":"COMPLETED","enrollment_count":176,"lead_sponsor_name":"Universiti Sains Malaysia","has_results":false},{"nct_id":"NCT06602466","title":"A Clinical Study Investigating the Effect of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival Health","phase":"NA","overall_status":"COMPLETED","enrollment_count":175,"lead_sponsor_name":"HALEON","has_results":true},{"nct_id":"NCT07169188","title":"A Clinical Study Investigating the Efficacy of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival Health","phase":"NA","overall_status":"COMPLETED","enrollment_count":154,"lead_sponsor_name":"HALEON","has_results":false},{"nct_id":"NCT06910501","title":"Comparative Effectiveness of Various Educational Approaches on Oral Hygiene","phase":"NA","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Ege University","has_results":false},{"nct_id":"NCT05782348","title":"Evaluating the Effectiveness of a Cognitive Behavioral Intervention (CBI)","phase":"NA","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Howard University","has_results":false},{"nct_id":"NCT05723133","title":"Visual Feedback on Brushing Technique and Habits on Patient Oral Hygiene","phase":"NA","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"University Ghent","has_results":false},{"nct_id":"NCT06358742","title":"Evaluation of the Effect of Zinc Citrate Trihydrate Toothpaste on the Oral Plaque Microbiome","phase":"NA","overall_status":"COMPLETED","enrollment_count":142,"lead_sponsor_name":"Unilever R&D","has_results":false},{"nct_id":"NCT02940821","title":"Assessing the Effects of Three Oral Care Regimens","phase":"NA","overall_status":"COMPLETED","enrollment_count":142,"lead_sponsor_name":"Pearl Network","has_results":false},{"nct_id":"NCT06933368","title":"A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation","phase":"NA","overall_status":"COMPLETED","enrollment_count":136,"lead_sponsor_name":"HALEON","has_results":false},{"nct_id":"NCT03101943","title":"Preventing Early Childhood Obesity, Part 1: Family Spirit Nurture, 3-9 Months","phase":"NA","overall_status":"COMPLETED","enrollment_count":136,"lead_sponsor_name":"Johns Hopkins Bloomberg School of Public Health","has_results":false},{"nct_id":"NCT05788692","title":"Effectiveness of Toothbrushing Habits of Preschool Children, With or Without a Toothbrushing Assisting Application","phase":"NA","overall_status":"COMPLETED","enrollment_count":130,"lead_sponsor_name":"National and Kapodistrian University of Athens","has_results":false},{"nct_id":"NCT05146557","title":"Associations Between Obesity, Dental Caries, Erosive Tooth Wear and Periodontal Disease in Adolescents: A Case Control-study","phase":"","overall_status":"COMPLETED","enrollment_count":125,"lead_sponsor_name":"University Ghent","has_results":false},{"nct_id":"NCT06164496","title":"Evaluation of the Effectiveness of Different Toothbrushes in Children","phase":"NA","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"Marmara University","has_results":false},{"nct_id":"NCT06286501","title":"Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases","phase":"NA","overall_status":"RECRUITING","enrollment_count":120,"lead_sponsor_name":"Wellbeing Services County of Pirkanmaa","has_results":false},{"nct_id":"NCT03154021","title":"Next Science Antimicrobial Mouth Rinse Study","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":118,"lead_sponsor_name":"University of Florida","has_results":false},{"nct_id":"NCT03624647","title":"A Clinical Comparison of an Experimental Power Brush Compared to a Manual Toothbrush","phase":"NA","overall_status":"COMPLETED","enrollment_count":110,"lead_sponsor_name":"Procter and Gamble","has_results":false},{"nct_id":"NCT06554938","title":"Efficacy of Dental Hygiene Aids in Reducing Gingival Bleeding and Plaque Among Orthodontic Patients.","phase":"NA","overall_status":"COMPLETED","enrollment_count":102,"lead_sponsor_name":"Ajman University","has_results":false},{"nct_id":"NCT06779279","title":"Adjunctive Oral Hygiene Aids in Reducing Oral Hygiene Parameters Among Orthodontic Patients","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":102,"lead_sponsor_name":"sudhir rama varma","has_results":false},{"nct_id":"NCT05304338","title":"Evaluation of the Effect of Oil Pulling","phase":"NA","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"Ataturk University","has_results":false},{"nct_id":"NCT06789835","title":"Automated Quantification of Dental Plaque","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"University of Aarhus","has_results":false},{"nct_id":"NCT06358482","title":"Electric Toothbrush Efficacy in Preventing Dental Plaque Development","phase":"NA","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"Riccardo Polosa","has_results":false},{"nct_id":"NCT03852056","title":"The Clinical Investigation of a New Toothpaste Containing Stannous Fluoride as Compared to a Commercially Available Fluoride Toothpaste in Reducing Plaque and Gingivitis","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":98,"lead_sponsor_name":"Colgate Palmolive","has_results":false},{"nct_id":"NCT06963788","title":"The Comparative Effects of Using 0.12% Chlorhexidine and Silver Nanoparticles Mouthwashes in Medical Students","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":95,"lead_sponsor_name":"Can Tho University of Medicine and Pharmacy","has_results":false},{"nct_id":"NCT07419737","title":"Dental Plaque Prevention Efficacy of a Stannous Fluoride Toothpaste","phase":"NA","overall_status":"COMPLETED","enrollment_count":91,"lead_sponsor_name":"Church & Dwight Company, Inc.","has_results":false},{"nct_id":"NCT06240481","title":"Clinical Research Study to Assess the Efficacy of Two Brushing Regimens","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Colgate Palmolive","has_results":false},{"nct_id":"NCT05439785","title":"Plaque Control Efficacy Between Interdental Brushes Versus Dental Floss","phase":"NA","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Fatima Jinnah Dental College","has_results":false},{"nct_id":"NCT03416985","title":"A Comparative Study of Electric Toothbrushes for the Efficacy Plaque Removal and the Effect on Plaque Accumulation and Gingivitis.","phase":"NA","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"University of California, Los Angeles","has_results":true},{"nct_id":"NCT01462110","title":"A Four-Week Study to Measure the Effectiveness of an Experimental Mouthwash Used After Teeth Cleaning","phase":"NA","overall_status":"COMPLETED","enrollment_count":87,"lead_sponsor_name":"Johnson & Johnson Consumer and Personal Products Worldwide","has_results":true},{"nct_id":"NCT05999175","title":"Open-label Trial Evaluating Four Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste, and Mouthwash","phase":"NA","overall_status":"COMPLETED","enrollment_count":84,"lead_sponsor_name":"Biokosmes Srl","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}