{"disease":{"id":"degeneration-of-intervertebral-disc","name":"Degeneration of intervertebral disc","therapeutic_area":"","data":{},"enrichment_level":0,"last_enriched_at":null,"visit_count":0,"created_at":"2026-04-19T18:31:21.150Z","updated_at":"2026-04-19T18:39:44.960Z","meddra_pt":null,"meddra_code":null,"icd10_codes":null,"synonyms":[],"prevalence_global":null,"prevalence_us":null,"marketed_drug_count":1,"pipeline_drug_count":0,"trial_count":0},"drugs":{"marketed":[{"drug_id":"dibotermin-alfa","indication_name":"Degeneration of intervertebral disc","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Inductos","generic_name":"DIBOTERMIN ALFA","company_name":"Medtronic BioPharma B.V.","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":20,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05101057","title":"A Retrospective Study to Examine the Effect of CMF Stimulation on Primary ACDF Patients","phase":"","overall_status":"UNKNOWN","enrollment_count":400,"lead_sponsor_name":"Encore Medical, L.P.","has_results":false},{"nct_id":"NCT01934868","title":"Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":110,"lead_sponsor_name":"Hadassah Medical Organization","has_results":false},{"nct_id":"NCT06704906","title":"Adult Patient Outcomes After Spine Surgery With Fibergraft BG Putty/Viper Prime","phase":"","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"Nitin Agarwal","has_results":false},{"nct_id":"NCT07001969","title":"Percutaneous Trans-facet Spine Fixation","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":77,"lead_sponsor_name":"Mahmoud Massoud","has_results":false}],"total":4},"guidelines":[],"source":"Drug Landscape verified database"}