{"disease":{"id":"defects","name":"defects"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06048276","title":"Miscarriage Preventing Herbal Medicines and the Risk of Birth Defects: a Population-based Cohort Study","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":200000,"lead_sponsor_name":"West China Hospital","has_results":false},{"nct_id":"NCT07514377","title":"JiGenerations Health Cohort Study：Parental Exposure and Intergenerational Health in China","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":100000,"lead_sponsor_name":"National Research Institute for Family Planning, China","has_results":false},{"nct_id":"NCT04182503","title":"Environmental Factors and Embryonic Development Project","phase":"","overall_status":"UNKNOWN","enrollment_count":100000,"lead_sponsor_name":"Jinling Hospital, China","has_results":false},{"nct_id":"NCT05883761","title":"Birth Outcomes In Eswatini After Transition To Dolutegravir-Based Treatment","phase":"","overall_status":"COMPLETED","enrollment_count":50075,"lead_sponsor_name":"Elizabeth Glaser Pediatric AIDS Foundation","has_results":false},{"nct_id":"NCT06324682","title":"ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","phase":"","overall_status":"RECRUITING","enrollment_count":8400,"lead_sponsor_name":"University Hospital of Ferrara","has_results":false},{"nct_id":"NCT00341068","title":"Genetic Analysis of Neural Tube and Orofacial Cleft Defects in the Irish Population","phase":"","overall_status":"TERMINATED","enrollment_count":7451,"lead_sponsor_name":"National Human Genome Research Institute (NHGRI)","has_results":false},{"nct_id":"NCT07375602","title":"A Multimodal AI Prediction Model for Complications After Transcatheter Closure of Perimembranous VSD in Children","phase":"","overall_status":"RECRUITING","enrollment_count":5249,"lead_sponsor_name":"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","has_results":false},{"nct_id":"NCT03725878","title":"Effectiveness of Comprehensive Tertiary Interventions on Incidence and Clinical Outcomes of Birth Defects","phase":"NA","overall_status":"COMPLETED","enrollment_count":4808,"lead_sponsor_name":"Children's Hospital of Fudan University","has_results":false},{"nct_id":"NCT05709470","title":"Mind the Heart - Mental Health in Children and Adolescents With Congenital Heart Defects","phase":"","overall_status":"RECRUITING","enrollment_count":4800,"lead_sponsor_name":"Rigshospitalet, Denmark","has_results":false},{"nct_id":"NCT00340977","title":"Svangerskap, Arv, Og Miljo (Pregnancy, Heredity and Environment)","phase":"","overall_status":"COMPLETED","enrollment_count":4091,"lead_sponsor_name":"National Institute of Environmental Health Sciences (NIEHS)","has_results":false},{"nct_id":"NCT00001355","title":"Detection and Characterization of Host Defense Defects","phase":"","overall_status":"RECRUITING","enrollment_count":3600,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":false},{"nct_id":"NCT03215368","title":"The Ma'Anshan Birth Cohort (MABC)","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":3474,"lead_sponsor_name":"Anhui Medical University","has_results":false},{"nct_id":"NCT04141605","title":"Global Utilization And Registry Database for Improved heArt preservatioN","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":3000,"lead_sponsor_name":"Paragonix Technologies","has_results":false},{"nct_id":"NCT03957512","title":"Livet Skal Leves (A Life to Live)","phase":"","overall_status":"COMPLETED","enrollment_count":3000,"lead_sponsor_name":"Oslo University Hospital","has_results":false},{"nct_id":"NCT06442592","title":"Characterization and Support for Neurodevelopmental Disorders Associated With Congenital Heart Defects","phase":"NA","overall_status":"RECRUITING","enrollment_count":1206,"lead_sponsor_name":"Nantes University Hospital","has_results":false},{"nct_id":"NCT06034392","title":"CHAMP App Cardiac Study and Repository","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":1000,"lead_sponsor_name":"Lori Erickson","has_results":false},{"nct_id":"NCT03356574","title":"Long-term Survival After Single-ventricle Palliation","phase":"","overall_status":"UNKNOWN","enrollment_count":800,"lead_sponsor_name":"Karolinska University Hospital","has_results":false},{"nct_id":"NCT05205356","title":"VIGOR: Virtual Genome Center for Infant Health","phase":"","overall_status":"RECRUITING","enrollment_count":750,"lead_sponsor_name":"Boston Children's Hospital","has_results":false},{"nct_id":"NCT04866537","title":"Evaluation of the Diagnostic Performance of Specialized Fetal Cardiac Ultrasound in the CPDPN - Arc Alpin Network","phase":"","overall_status":"UNKNOWN","enrollment_count":679,"lead_sponsor_name":"University Hospital, Grenoble","has_results":false},{"nct_id":"NCT05330338","title":"Genetics of Ventriculo-arterial Discordance","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":600,"lead_sponsor_name":"Nantes University Hospital","has_results":false},{"nct_id":"NCT06089902","title":"European Prospective Registry on Anomalous Aortic Origin of the Coronary Arteries","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"University of Padova","has_results":false},{"nct_id":"NCT01294345","title":"Personalized Genomic Research","phase":"","overall_status":"COMPLETED","enrollment_count":353,"lead_sponsor_name":"National Human Genome Research Institute (NHGRI)","has_results":false},{"nct_id":"NCT07395180","title":"Differentiation of Human Body Balance Disorders","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":330,"lead_sponsor_name":"Military Institute od Medicine National Research Institute","has_results":false},{"nct_id":"NCT00766571","title":"Clinical and Genetic Studies of VACTERL Association","phase":"","overall_status":"COMPLETED","enrollment_count":304,"lead_sponsor_name":"National Human Genome Research Institute (NHGRI)","has_results":false},{"nct_id":"NCT04764305","title":"Liver Disease, Myocardial Fibrosis and Collaterals in the Adult Fontan Patient a Metabolomics and Proteomics Approach","phase":"","overall_status":"UNKNOWN","enrollment_count":300,"lead_sponsor_name":"Medical University Innsbruck","has_results":false},{"nct_id":"NCT07339111","title":"Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Medipost, Inc.","has_results":false},{"nct_id":"NCT04606355","title":"Autostereoscopic Dynamic Near Vision Testing","phase":"","overall_status":"SUSPENDED","enrollment_count":300,"lead_sponsor_name":"Alaska Blind Child Discovery","has_results":false},{"nct_id":"NCT04098146","title":"Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis","phase":"","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"AO Innovation Translation Center","has_results":false},{"nct_id":"NCT06135883","title":"Assessing Folic Acid in High-Risk Pregnancy for Neural Tube Defects","phase":"","overall_status":"COMPLETED","enrollment_count":267,"lead_sponsor_name":"Karabuk University","has_results":false},{"nct_id":"NCT07300358","title":"Study on the Safety and Effectiveness of a Biodegradable Patent Foramen Ovale Occluder System","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":258,"lead_sponsor_name":"Shanghai Lingsi Medical Technology Co., Ltd.","has_results":false},{"nct_id":"NCT03299959","title":"Agili-C™ Implant Performance Evaluation","phase":"NA","overall_status":"COMPLETED","enrollment_count":251,"lead_sponsor_name":"Smith & Nephew, Inc.","has_results":true},{"nct_id":"NCT06734611","title":"Folic Acid Salt Study (FISFA Zambia)","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":250,"lead_sponsor_name":"University of Alabama at Birmingham","has_results":false},{"nct_id":"NCT04825821","title":"Cesarean Scar Defects After Uterine Closure by Double-layer Barbed or Smooth Suture","phase":"","overall_status":"COMPLETED","enrollment_count":247,"lead_sponsor_name":"Ospedale Policlinico San Martino","has_results":false},{"nct_id":"NCT04437745","title":"To Evaluate the Effectiveness and Safety of YVOIRE Y-Solution 720 Injected Into the Mid-Face","phase":"NA","overall_status":"COMPLETED","enrollment_count":238,"lead_sponsor_name":"LG Chem","has_results":false},{"nct_id":"NCT07415577","title":"The Use of Cultured (Dermal) Epithelial Autografts in Severely Burned Patients","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":236,"lead_sponsor_name":"University Children's Hospital, Zurich","has_results":false},{"nct_id":"NCT02055248","title":"Study on Moebius Syndrome and Congenital Facial Weakness Disorders","phase":"","overall_status":"COMPLETED","enrollment_count":207,"lead_sponsor_name":"National Human Genome Research Institute (NHGRI)","has_results":false},{"nct_id":"NCT03651765","title":"Long Term Extension Trial of Setmelanotide","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":205,"lead_sponsor_name":"Rhythm Pharmaceuticals, Inc.","has_results":true},{"nct_id":"NCT05481580","title":"Restorations and Furcation Involvement on Molars","phase":"","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"University of Cagliari","has_results":false},{"nct_id":"NCT05318222","title":"Genetic Inclusion by Virtual Evaluation","phase":"NA","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"Baylor College of Medicine","has_results":false},{"nct_id":"NCT06904612","title":"Using Iodized Salt to Improve Serum Folate, B12 and Iron Levels","phase":"","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Hydrocephalus and Neuroscience Institute","has_results":false},{"nct_id":"NCT07085533","title":"Natural History Study of Inherited Retinal Diseases","phase":"","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"Zhongmou Therapeutics","has_results":false},{"nct_id":"NCT06270303","title":"Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects","phase":"NA","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"Göteborg University","has_results":false},{"nct_id":"NCT06533150","title":"Functionalized Bioink Delivering Biomolecules for the Treatment of Craniofacial Diseases","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":180,"lead_sponsor_name":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","has_results":false},{"nct_id":"NCT04354220","title":"Capnography Monitoring in Ventilated Children","phase":"","overall_status":"UNKNOWN","enrollment_count":178,"lead_sponsor_name":"Vincenzo Cannizzaro","has_results":false},{"nct_id":"NCT04851847","title":"A Clinical Trial to Evaluate the Safety and Effectiveness of Resorbable Collagen Membrane - MatrixflexTM","phase":"NA","overall_status":"UNKNOWN","enrollment_count":174,"lead_sponsor_name":"Collagen Matrix","has_results":false},{"nct_id":"NCT03601039","title":"Safety and Efficacy Study of Absnow Absorbable ASD Closure System For Treating ASD Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":165,"lead_sponsor_name":"Lifetech Scientific (Shenzhen) Co., Ltd.","has_results":true},{"nct_id":"NCT06822400","title":"Investigation of Tetralogy of Fallot in Neonates","phase":"NA","overall_status":"RECRUITING","enrollment_count":160,"lead_sponsor_name":"Beijing Anzhen Hospital","has_results":false},{"nct_id":"NCT03307668","title":"Study on Efficacy and Safety of CaReSR-1S to Repair Cartilage Defects of the Knee","phase":"NA","overall_status":"UNKNOWN","enrollment_count":160,"lead_sponsor_name":"Arthro-Anda Tianjin Biologic Technology Co., Ltd.","has_results":false},{"nct_id":"NCT06959459","title":"Evaluation of the Safety and Efficacy of Artificial Bone Repair Materials for Repair of Long Bone Defects in the Extremities","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":156,"lead_sponsor_name":"Chinese PLA General Hospital","has_results":false},{"nct_id":"NCT05369949","title":"DEX vs SEVO in Congenital Heart Surgery","phase":"PHASE4","overall_status":"NOT_YET_RECRUITING","enrollment_count":150,"lead_sponsor_name":"Cliniques universitaires Saint-Luc- Université Catholique de Louvain","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}