{"disease":{"id":"decompensated-cirrhosis-of-liver","name":"Decompensated cirrhosis of liver","therapeutic_area":"","data":{},"enrichment_level":0,"last_enriched_at":null,"visit_count":0,"created_at":"2026-04-19T18:31:21.150Z","updated_at":"2026-04-19T18:39:44.960Z","meddra_pt":null,"meddra_code":null,"icd10_codes":null,"synonyms":[],"prevalence_global":null,"prevalence_us":null,"marketed_drug_count":1,"pipeline_drug_count":0,"trial_count":0},"drugs":{"marketed":[{"drug_id":"sovaldi","indication_name":"Decompensated cirrhosis of liver","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"Sovaldi","company_name":"Genuine Research Center, Egypt","drug_phase":"marketed","molecular_target":"Cereblon isoform 4, Genome polyprotein, NS5","drug_class":"","quality_score":16,"revenue":null,"mechanism":null}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06977685","title":"Effect of Non-Selective Beta-Blockers on Outcomes in Cirrhosis Patients After Hospitalization: A Retrospective Cohort Using Target Trial Design","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":7725,"lead_sponsor_name":"Samsung Medical Center","has_results":false},{"nct_id":"NCT03540771","title":"Introducing Palliative Care (PC) Within the Treatment of End Stage Liver Disease (ESLD)","phase":"NA","overall_status":"COMPLETED","enrollment_count":1494,"lead_sponsor_name":"Albert Einstein Healthcare Network","has_results":true},{"nct_id":"NCT06855056","title":"Validation of New Prognostic Biomarkers in Patients With Decompensated Cirrhosis","phase":"","overall_status":"RECRUITING","enrollment_count":189,"lead_sponsor_name":"European Foundation for Study of Chronic Liver Failure","has_results":false},{"nct_id":"NCT07439770","title":"Using Telemedicine to Assist in the Clinical Care of Patients With Decompensated Cirrhosis","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":120,"lead_sponsor_name":"National Taiwan University Hospital","has_results":false},{"nct_id":"NCT06937307","title":"Droxidopa to Increase Mean Arterial Pressure in Decompensated Cirrhosis Patients With Acute Kidney Injury","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":75,"lead_sponsor_name":"Giuseppe Cullaro, MD","has_results":false},{"nct_id":"NCT03911037","title":"GCSF Therapy in Decompensated Cirrhosis - A Double Blinded RCT","phase":"PHASE2, PHASE3","overall_status":"UNKNOWN","enrollment_count":70,"lead_sponsor_name":"Post Graduate Institute of Medical Education and Research, Chandigarh","has_results":false},{"nct_id":"NCT06823713","title":"RTX001 Autologous Engineered Macrophages for Liver Cirrhosis","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":30,"lead_sponsor_name":"Resolution Therapeutics Limited","has_results":false}],"total":7},"guidelines":[],"source":"Drug Landscape verified database"}