{"disease":{"id":"cryotherapy-effect","name":"cryotherapy effect"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05011084","title":"Combined Cryotherapy With Compression Versus Cryotherapy Alone After Orthopaedic Surgery","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":348,"lead_sponsor_name":"Walter Reed National Military Medical Center","has_results":false},{"nct_id":"NCT06356831","title":"National Registry of Surgical Treatment and Percutaneous Cryoablation of Parietal Endometriosis","phase":"","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Centre Hospitalier Intercommunal Creteil","has_results":false},{"nct_id":"NCT04339218","title":"Cryoablation in Combination (or Not) With Pembrolizumab and Pemetrexed-carboplatin in 1st-line Treatment for Patients With Metastatic Lung Adenocarcinoma","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":214,"lead_sponsor_name":"Institut Bergonié","has_results":false},{"nct_id":"NCT03973385","title":"Evaluation of Efficacy of Cryotherapy for Skin Anesthesia During Arterial Puncture","phase":"NA","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Versailles Hospital","has_results":false},{"nct_id":"NCT05692427","title":"Evaluation of Cryotherapy in Granuloma Pyogenicum","phase":"NA","overall_status":"RECRUITING","enrollment_count":200,"lead_sponsor_name":"Medical University of Graz","has_results":false},{"nct_id":"NCT03203733","title":"Cryoprotection of Chemotherapy-induced Oral Mucositis After Autologous Stem Cell Transplantation, a Randomized Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":182,"lead_sponsor_name":"Uppsala University","has_results":false},{"nct_id":"NCT03341533","title":"Abdominal Ice Packs for Pain Control and Reduction of Narcotic Use Following Laparoscopic Hysterectomy","phase":"NA","overall_status":"COMPLETED","enrollment_count":142,"lead_sponsor_name":"Mayo Clinic","has_results":true},{"nct_id":"NCT05091554","title":"Intraoral Cryotherapy in Root Canal Retreatment","phase":"NA","overall_status":"COMPLETED","enrollment_count":118,"lead_sponsor_name":"Izmir Katip Celebi University","has_results":false},{"nct_id":"NCT05348447","title":"Intercostal Nerve Cryotherapy in Patients Undergoing Minimally Invasive Pulmonary Resection","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":110,"lead_sponsor_name":"Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)","has_results":false},{"nct_id":"NCT03704597","title":"Cryotherapy Against Oral Mucositis After High-dose Melphalan","phase":"NA","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Sahlgrenska University Hospital","has_results":false},{"nct_id":"NCT04164511","title":"Does Ice Cream Help With Post-tonsillectomy Pain","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"University Hospital Sestre Milosrdnice","has_results":false},{"nct_id":"NCT06293209","title":"Effect of Cool Spray and Cold Packs in Reducing Preoperative Edema and Pain in Ankle Fractures in Ubonratchathani","phase":"NA","overall_status":"UNKNOWN","enrollment_count":90,"lead_sponsor_name":"Thai Traditional Medical Knowledge Fund","has_results":false},{"nct_id":"NCT07264829","title":"This Clinical Trial Aims to Compare the Effectiveness of Two Intra-pulpal Cryotherapy Techniques-Endo-ice and Ice Sticks-in Decreasing Intra-operative Pain and Enhancing the Success of Local Anesthesia During Pulpectomy of Mandibular Molars With Symptomatic Irreversible Pulpitis.","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":90,"lead_sponsor_name":"Dow University of Health Sciences","has_results":false},{"nct_id":"NCT04119297","title":"Effects of Cold Application and Heparinoid on Periorbital Edema and Ecchymosis","phase":"NA","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"Necmettin Erbakan University","has_results":false},{"nct_id":"NCT05251688","title":"Cryoanalgesia for Arterial Puncture Pain","phase":"NA","overall_status":"COMPLETED","enrollment_count":86,"lead_sponsor_name":"Mansoura University","has_results":false},{"nct_id":"NCT05884099","title":"Intercostal Cryoanalgesia for Chronic Pain After VATS Lung Resection","phase":"NA","overall_status":"COMPLETED","enrollment_count":80,"lead_sponsor_name":"Centre hospitalier de l'Université de Montréal (CHUM)","has_results":false},{"nct_id":"NCT05896150","title":"Intercostal Cryoanalgesia for Acute Pain After VATS Lung Resection","phase":"NA","overall_status":"COMPLETED","enrollment_count":80,"lead_sponsor_name":"Centre hospitalier de l'Université de Montréal (CHUM)","has_results":false},{"nct_id":"NCT05476445","title":"Effect of Cryotherapy and LLLT on Postoperative Pain After Root Canal Treatment","phase":"NA","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Ataturk University","has_results":false},{"nct_id":"NCT05355584","title":"Acute Effects of Cryotherapy Duration in Healthy Individuals","phase":"NA","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Burcu Camcıoğlu Yılmaz","has_results":false},{"nct_id":"NCT06629285","title":"Effectiveness Comparison Between Continuous Cryotherapy and Ice Pack Therapy After Anterior Cruciate Ligament Reconstruction Surgery","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":72,"lead_sponsor_name":"University Medical Center Ho Chi Minh City (UMC)","has_results":false},{"nct_id":"NCT06223490","title":"Effect of Cryolipolysis on Insulin Resistance","phase":"NA","overall_status":"UNKNOWN","enrollment_count":60,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT04512664","title":"Different Cold Application Times on Ecchmosis, Edema and Pain After Rhinoplasty","phase":"NA","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"University of Beykent","has_results":false},{"nct_id":"NCT04222933","title":"Effect of Motorized Cryotherapy on Early Effusion, Swelling, and Pain After Anterior Cruciate Ligament Reconstruction","phase":"NA","overall_status":"COMPLETED","enrollment_count":56,"lead_sponsor_name":"Hanyang University Seoul Hospital","has_results":false},{"nct_id":"NCT04710277","title":"Novel Multimodal Pain Control Protocol for Minimally Invasive Gynecologic Surgery","phase":"NA","overall_status":"COMPLETED","enrollment_count":54,"lead_sponsor_name":"Ohio State University","has_results":false},{"nct_id":"NCT06970366","title":"Cryotherapy on Muscle Function","phase":"NA","overall_status":"COMPLETED","enrollment_count":52,"lead_sponsor_name":"Okan University","has_results":false},{"nct_id":"NCT06608836","title":"Acute Effects of Cryotherapy on Muscle Properties","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":52,"lead_sponsor_name":"Istanbul University - Cerrahpasa","has_results":false},{"nct_id":"NCT06005727","title":"Cryotherapy Post-haemorrhoidectomy (CYPHER) Randomized Controlled Trial","phase":"NA","overall_status":"UNKNOWN","enrollment_count":50,"lead_sponsor_name":"Singapore General Hospital","has_results":false},{"nct_id":"NCT04201977","title":"Comparison of Different Forms of Recovery on the Functionality After Physical Exercise","phase":"NA","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"Universidade Federal de Santa Maria","has_results":false},{"nct_id":"NCT03850392","title":"Anti Inflammatory Effects of Local Cryotherapy in Knee Arthritis","phase":"NA","overall_status":"COMPLETED","enrollment_count":47,"lead_sponsor_name":"Centre Hospitalier Universitaire de Besancon","has_results":false},{"nct_id":"NCT03776734","title":"Effects of Cold Application on Exercise Performance","phase":"NA","overall_status":"UNKNOWN","enrollment_count":45,"lead_sponsor_name":"Eastern Mediterranean University","has_results":false},{"nct_id":"NCT06037824","title":"Compressive Cryotherapy Versus Conventional Cryotherapy After Total Knee Arthroplasty","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"Institut de Formation en Masso-Kinésithérapie Saint Michel","has_results":false},{"nct_id":"NCT05395273","title":"Cryocompression After Total Knee Arthroplasty","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"University of Applied Sciences and Arts of Southern Switzerland","has_results":false},{"nct_id":"NCT06531265","title":"Cryotechnique as a Diagnostic and Therapeutic Tool of Endobronchial Tumors","phase":"NA","overall_status":"COMPLETED","enrollment_count":35,"lead_sponsor_name":"Sohag University","has_results":false},{"nct_id":"NCT03185507","title":"The Effect of Cryotherapy on Cerebral Hemodynamics Within Healthy Subjects","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":34,"lead_sponsor_name":"University of Virginia","has_results":false},{"nct_id":"NCT06939374","title":"Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With Stable Angina or ACS - A Traditional Feasibility Study","phase":"NA","overall_status":"RECRUITING","enrollment_count":30,"lead_sponsor_name":"Cryotherapeutics SA","has_results":false},{"nct_id":"NCT05600088","title":"Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With (N)STEMI or Unstable Angina","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":30,"lead_sponsor_name":"Cryotherapeutics SA","has_results":false},{"nct_id":"NCT04287153","title":"Cryotherapy and Body Slimming","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Clinic Cryo Esthetic","has_results":false},{"nct_id":"NCT01177787","title":"Clinical Efficacy of Cryolipolysis on the Fat of Thigh in Korean Women","phase":"NA","overall_status":"COMPLETED","enrollment_count":28,"lead_sponsor_name":"Wonik Trade Company, Korea","has_results":true},{"nct_id":"NCT03151031","title":"Effect on Dynamic Postural Stability After Application of Cryotherapy to the Knee Joint","phase":"NA","overall_status":"COMPLETED","enrollment_count":24,"lead_sponsor_name":"Asir John Samuel","has_results":false},{"nct_id":"NCT04781244","title":"Cost-effectiveness of EndWarts® FREEZE - an Alternative Home Cryotherapy Device for Wart Treatment","phase":"NA","overall_status":"COMPLETED","enrollment_count":22,"lead_sponsor_name":"Mahidol University","has_results":false},{"nct_id":"NCT04019392","title":"Rate of Tissue Temperature Reduction Between Wetted Ice and Game Ready","phase":"NA","overall_status":"COMPLETED","enrollment_count":20,"lead_sponsor_name":"North Dakota State University","has_results":false},{"nct_id":"NCT06491771","title":"A Cryotherapy With Tranexamic Acid Versus Normal Saline in the Treatment of Melasma","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":18,"lead_sponsor_name":"Mahidol University","has_results":false},{"nct_id":"NCT03911830","title":"Aerobic Exercise Program Followed by Cold Water Immersion: Effects on Arthritis Patients Arterial Stiffness","phase":"NA","overall_status":"COMPLETED","enrollment_count":18,"lead_sponsor_name":"Centre Hospitalier Universitaire de Besancon","has_results":false},{"nct_id":"NCT04793815","title":"Lung Cancer Cryo-Activation as a Novel Approach to Augment Immunotherapy Efficacy (CRYOVATE)","phase":"NA","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"Centre hospitalier de l'Université de Montréal (CHUM)","has_results":false},{"nct_id":"NCT06079437","title":"The Effect of Brief Skin Cooling on Isometric Muscle Strength","phase":"NA","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"Istanbul Physical Medicine Rehabilitation Training and Research Hospital","has_results":false},{"nct_id":"NCT03643835","title":"Efficacy of an Investigational Thermal Rehab Machine on Body Cooling in Hyperthermic Individuals","phase":"NA","overall_status":"COMPLETED","enrollment_count":14,"lead_sponsor_name":"University of North Carolina, Greensboro","has_results":false},{"nct_id":"NCT04558034","title":"The Use of Cryotherapy to Prevent Paclitaxel-induced Peripheral Neuropathy and Nail Changes in Women With Breast Cancer","phase":"NA","overall_status":"TERMINATED","enrollment_count":14,"lead_sponsor_name":"Parkview Health","has_results":false},{"nct_id":"NCT04190264","title":"Body Cooling in Hyperthermic Males and Females","phase":"NA","overall_status":"COMPLETED","enrollment_count":12,"lead_sponsor_name":"University of North Carolina, Greensboro","has_results":false},{"nct_id":"NCT05832970","title":"Cooling Induces Motor Facilitation With Sympathetic Activation","phase":"NA","overall_status":"COMPLETED","enrollment_count":11,"lead_sponsor_name":"Istanbul Physical Medicine Rehabilitation Training and Research Hospital","has_results":false}],"total":49},"guidelines":[],"source":"Drug Landscape verified database"}